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The map label for this gene is cat1 [H]

Identifier: 145294654

GI number: 145294654

Start: 673713

End: 675188

Strand: Direct

Name: cat1 [H]

Synonym: cgR_0604

Alternate gene names: 145294654

Gene position: 673713-675188 (Clockwise)

Preceding gene: 145294649

Following gene: 145294655

Centisome position: 20.33

GC content: 51.69

Gene sequence:

>1476_bases
ATGTCGGCGGAGGAAGCGGCCCAATTTATCAACAACGGCGCCACGGTGGGAATGTCCGGTTTCACCGGGGCGGCTTACCC
CAAAGCTTTGCCCACGGCTATCGCCAATCGCGCCAAACAGGAACATGCAGCCGGCCGTGAATATGGCATCAGAATGCTCA
CCGGTGCATCCACGGCACCGGATTGTGATGGCGTGCTTGCTGAAGCCGATGCGTTGAGCTTCCGTATGCCTTATCAATCA
GATCCTGCGATGCGTGGGAAAATCAACGCGGGGCAGCTGAACTACCAAGACATTCACCTTTCGCATTCAGGCCTGCAGGT
TGAACAAGGATTCTTTGGTGCCATTGACATTGCAATCGTTGAGGTTGCGCGCATTACAAAAGAGGGCCATCTGATTCCTT
CCTCGGGTGTGGGAAATAACGTGGAGTATCTTGATGCAGCACAACACATCATTCTTGAGGTCAATTCCTGGCAATCCCTC
GATCTTGAAGGCATGGCCGATATCTACCGTGTTCCACATTTGCCTCACCGCACGCCGATCCCGATTGAAAAAGTTGGCGA
TCGCGTGGGCACGACTTTCATAGATATTGATATAGCCAAGGTTATTGCTGTCGTGGAAACCGATGCCCCAGACCGCAACA
GTCCATTCAAGCCTTTCGATGAAGTGTCCAAACAAATCGCAGGAAACTACCTGGACTTCCTCGACGGGGAGGTGGCTGGC
GGGCGTCTTGCTTACGATCACTACATCATGCAATCCGGTGTTGGAAATGTCCCTAATGCAGTCATGGCGGGTTTGCTGGA
TTCCAAATTTGAAAACATTCAGGCATACACCGAGGTCGTTCAAGACGGAATGCTTGATTTGATCGATGCTGGAAAGATGG
CAGTGGCTTCTGCAACGTCGTTTGCGCTGTCACCAGAATATGCAGAGAAAATGAACCGGGAAGCAGAAAAGTACCGAAAG
TATCTGGTGTTGCGTCCGCTGCAAATATCTAATAGCCCGGAAGTTATTCGGCGCATGGGCCTTATTTCATCCAACGGCAT
GATCGAGGCTGATATATATGGAAATATCAACTCCACCCACGTTGCGGGTACGCGCGTGATGAATGGTATCGGCGGCTCGG
GCGATTTCACGCGTAACGCCTTTGCTTCCACATTTATCTCTCCGTCGGCAGCCAAAGGTGATGCGATTTCCGCGATTGTG
CCTTTCGCGTCCCATATCGATCACACGGAACATGATGCGATGGTTGTCATTACTGAATATGGCTACGCAGACCTGCGCGG
GCTATCGCCAAAACAACGAGTCCCCAAAATGATTGCCATCGCCCACCCGGACTATCGACCACTGCTGGAAGAGTACTTTG
ACCGGGCGTTAACCAGTGCAGACTCTTATCAGCACACCCCGCATGATCTGCGCACCGCCTTCGATTTCCATAATCGCTTG
AACTCGCAAGGAACCATGAAAATCGAAAAAGCATAG

Upstream 100 bases:

>100_bases
TATGTCATACACCACACTAAAAGTGATGTGATTCATAAGTGTGGAAAGGGTAGAAAAAATGTCGGAAAGAGTGCAAAACC
GCGAACTCAAGACAAAAATA

Downstream 100 bases:

>100_bases
CGCTTTTCGACGAGCCCCCCACCTTCGCCGCCACCAGAGTGCCGGCGGTCAATGTGGGTGGGCTATTTCACTGCGGGGCA
CTGAAAGTAAAAACGCAACT

Product: hypothetical protein

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MSAEEAAQFINNGATVGMSGFTGAAYPKALPTAIANRAKQEHAAGREYGIRMLTGASTAPDCDGVLAEADALSFRMPYQS
DPAMRGKINAGQLNYQDIHLSHSGLQVEQGFFGAIDIAIVEVARITKEGHLIPSSGVGNNVEYLDAAQHIILEVNSWQSL
DLEGMADIYRVPHLPHRTPIPIEKVGDRVGTTFIDIDIAKVIAVVETDAPDRNSPFKPFDEVSKQIAGNYLDFLDGEVAG
GRLAYDHYIMQSGVGNVPNAVMAGLLDSKFENIQAYTEVVQDGMLDLIDAGKMAVASATSFALSPEYAEKMNREAEKYRK
YLVLRPLQISNSPEVIRRMGLISSNGMIEADIYGNINSTHVAGTRVMNGIGGSGDFTRNAFASTFISPSAAKGDAISAIV
PFASHIDHTEHDAMVVITEYGYADLRGLSPKQRVPKMIAIAHPDYRPLLEEYFDRALTSADSYQHTPHDLRTAFDFHNRL
NSQGTMKIEKA

Sequences:

>Translated_491_residues
MSAEEAAQFINNGATVGMSGFTGAAYPKALPTAIANRAKQEHAAGREYGIRMLTGASTAPDCDGVLAEADALSFRMPYQS
DPAMRGKINAGQLNYQDIHLSHSGLQVEQGFFGAIDIAIVEVARITKEGHLIPSSGVGNNVEYLDAAQHIILEVNSWQSL
DLEGMADIYRVPHLPHRTPIPIEKVGDRVGTTFIDIDIAKVIAVVETDAPDRNSPFKPFDEVSKQIAGNYLDFLDGEVAG
GRLAYDHYIMQSGVGNVPNAVMAGLLDSKFENIQAYTEVVQDGMLDLIDAGKMAVASATSFALSPEYAEKMNREAEKYRK
YLVLRPLQISNSPEVIRRMGLISSNGMIEADIYGNINSTHVAGTRVMNGIGGSGDFTRNAFASTFISPSAAKGDAISAIV
PFASHIDHTEHDAMVVITEYGYADLRGLSPKQRVPKMIAIAHPDYRPLLEEYFDRALTSADSYQHTPHDLRTAFDFHNRL
NSQGTMKIEKA
>Mature_490_residues
SAEEAAQFINNGATVGMSGFTGAAYPKALPTAIANRAKQEHAAGREYGIRMLTGASTAPDCDGVLAEADALSFRMPYQSD
PAMRGKINAGQLNYQDIHLSHSGLQVEQGFFGAIDIAIVEVARITKEGHLIPSSGVGNNVEYLDAAQHIILEVNSWQSLD
LEGMADIYRVPHLPHRTPIPIEKVGDRVGTTFIDIDIAKVIAVVETDAPDRNSPFKPFDEVSKQIAGNYLDFLDGEVAGG
RLAYDHYIMQSGVGNVPNAVMAGLLDSKFENIQAYTEVVQDGMLDLIDAGKMAVASATSFALSPEYAEKMNREAEKYRKY
LVLRPLQISNSPEVIRRMGLISSNGMIEADIYGNINSTHVAGTRVMNGIGGSGDFTRNAFASTFISPSAAKGDAISAIVP
FASHIDHTEHDAMVVITEYGYADLRGLSPKQRVPKMIAIAHPDYRPLLEEYFDRALTSADSYQHTPHDLRTAFDFHNRLN
SQGTMKIEKA

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=488, Percent_Identity=44.672131147541, Blast_Score=406, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17538151, Length=396, Percent_Identity=26.5151515151515, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32563853, Length=245, Percent_Identity=29.3877551020408, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319456, Length=501, Percent_Identity=39.3213572854291, Blast_Score=350, Evalue=3e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 53368; Mature: 53237

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEEAAQFINNGATVGMSGFTGAAYPKALPTAIANRAKQEHAAGREYGIRMLTGASTAP
CCHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCEEEEECCCCCC
DCDGVLAEADALSFRMPYQSDPAMRGKINAGQLNYQDIHLSHSGLQVEQGFFGAIDIAIV
CCCCHHHCCCHHEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCHHHHHHH
EVARITKEGHLIPSSGVGNNVEYLDAAQHIILEVNSWQSLDLEGMADIYRVPHLPHRTPI
HHHHHHHCCCCCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCC
PIEKVGDRVGTTFIDIDIAKVIAVVETDAPDRNSPFKPFDEVSKQIAGNYLDFLDGEVAG
CHHHHHHHHCCEEEEEEHHHHHHEEECCCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCCC
GRLAYDHYIMQSGVGNVPNAVMAGLLDSKFENIQAYTEVVQDGMLDLIDAGKMAVASATS
CEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FALSPEYAEKMNREAEKYRKYLVLRPLQISNSPEVIRRMGLISSNGMIEADIYGNINSTH
HCCCHHHHHHHHHHHHHHHHHHEEECEECCCCHHHHHHHCCCCCCCEEEEEEECCCCCCC
VAGTRVMNGIGGSGDFTRNAFASTFISPSAAKGDAISAIVPFASHIDHTEHDAMVVITEY
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEC
GYADLRGLSPKQRVPKMIAIAHPDYRPLLEEYFDRALTSADSYQHTPHDLRTAFDFHNRL
CCHHHCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
NSQGTMKIEKA
CCCCCEEEECC
>Mature Secondary Structure 
SAEEAAQFINNGATVGMSGFTGAAYPKALPTAIANRAKQEHAAGREYGIRMLTGASTAP
CHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCEEEEECCCCCC
DCDGVLAEADALSFRMPYQSDPAMRGKINAGQLNYQDIHLSHSGLQVEQGFFGAIDIAIV
CCCCHHHCCCHHEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCHHHHHHH
EVARITKEGHLIPSSGVGNNVEYLDAAQHIILEVNSWQSLDLEGMADIYRVPHLPHRTPI
HHHHHHHCCCCCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCC
PIEKVGDRVGTTFIDIDIAKVIAVVETDAPDRNSPFKPFDEVSKQIAGNYLDFLDGEVAG
CHHHHHHHHCCEEEEEEHHHHHHEEECCCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCCC
GRLAYDHYIMQSGVGNVPNAVMAGLLDSKFENIQAYTEVVQDGMLDLIDAGKMAVASATS
CEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FALSPEYAEKMNREAEKYRKYLVLRPLQISNSPEVIRRMGLISSNGMIEADIYGNINSTH
HCCCHHHHHHHHHHHHHHHHHHEEECEECCCCHHHHHHHCCCCCCCEEEEEEECCCCCCC
VAGTRVMNGIGGSGDFTRNAFASTFISPSAAKGDAISAIVPFASHIDHTEHDAMVVITEY
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEC
GYADLRGLSPKQRVPKMIAIAHPDYRPLLEEYFDRALTSADSYQHTPHDLRTAFDFHNRL
CCHHHCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
NSQGTMKIEKA
CCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]