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The map label for this gene is ctpC [H]

Identifier: 145294634

GI number: 145294634

Start: 646142

End: 648094

Strand: Direct

Name: ctpC [H]

Synonym: cgR_0585

Alternate gene names: 145294634

Gene position: 646142-648094 (Clockwise)

Preceding gene: 145294633

Following gene: 145294635

Centisome position: 19.5

GC content: 52.33

Gene sequence:

>1953_bases
ATGCTGGTCAGTGACATTTTTATGGGTGATAATGGGGTTATGAATAAAAAACTTAATACCCCAAATCCCTGGATGTTATT
CATCCGCTCATTTGATGGCATCATCACTGTCGCAGCCCTTGTTGCCATCGCAATACATCTCATTTTATGGCTGGCTCTAG
ATCTTGATGGCCTTGCTAAAAACTGGCCTTTAATAGCCATCGTTATCCTAGGTGGCATTCCGTTGATGTGGGATGTGCTG
AAATCAGCCATTAAAACTCGCGGTGGCGCGGATACTTTAGCAGCAGTCTCCATCATTACTTCTGTGTTGTTAGGGGAGTG
GTTGGTTGCCGCGATCATCGTGCTCATGCTCTCTGGTGGTGAAGCGCTAGAAGAGGCAGCATCACGGCGAGCCAGTGGCA
CCTTGGACGCACTTGCCCGGCGCGCACCAAGTACAGCTCACCGCCTGTTGGGTGCAACCATTCTTGATGGAACCGAAGAG
ATCGCCGTGGAAGAGATCACGGTTGGTGATCTAGTGGCGGTGCTCCCGCATGAACTTTGCCCCGTGGATGGTGAAATCGT
GGCAGGCCACGGCACCATGGATGAGTCTTATCTCACGGGTGAGCCCTATGTGGTGAGTAAATCTAAAGGTTCACAAGCAA
TGTCGGGTGCAGTCAATGGTGATACTCCGCTGACGATTGTTGCCACAAAGCTTGCCCATGATTCCAGATACGCCCAAATT
GTTGGTGTACTTCATGAAGCAGAAAACAACCGCCCAGAAATGCGCAGGATGGCTGACCGTCTTGGCGCGTGGTATACGGT
GATTGCACTTGCCCTCGGTGGTCTTGGCTGGATTATCTCCGGCGACCCAGTGAGGTTCTTGGCTGTTGTCGTTGTCGCCA
CCCCATGTCCATTGCTCATTGCAGTGCCAGTGGCGATCATCGGTGCGATTTCCCTTGCGGCTCGTCGGGGCATCATCGTG
AAGAACCCTGGAATGCTGGAAAACGCTTCAGAAGTAAAGACAGTGATGTTCGATAAGACTGGAACGCTCACCTATGGCAG
GCCAGTGATTACTGATATCCACACTGCTCCCGGAGTTGAGGAAGATACAGTCCTAGCTTTGGCTGCTTCAGTAGAGCGCT
ATTCCAGGCACCCGTTGGCTGACGCGATTCGTGAGGGCGCAAAAGCCAGGGAACTTCATCTGCCTGATGTAGTGGAAGTA
TCGGAACGTCCAGGACAGGGACTAACCGGCACGGTGGGCGAGCACCTGGTTCGAATAACCAATAGGCGCAGCACACTAGA
AATTGATCCAGACAGTAAGAACTACATTCCGGTGACAAGTTCCGGCATGGAATCTGTGGTGCTTGTTGATGATAAATATG
CAGCACTCATTCGCCTCCGGGATGAACCTCGTGCATCTGCCAGTGAGTTCATCGCGCACTTGCCCAAGAAGCACAAAGTG
GACAAGCTCATGATTATCTCTGGTGATCGCGCATCTGAGGTTCGTTACCTTGCGGACAAGGTTGGCATCGATGAGGTACA
CGCAGAGGCCTCACCGGAAGACAAGCTGAACATTGTTAATCGGCATAATGAGCACGGCGCCACCATGTTCTTAGGTGATG
GAATCAACGATGCGCCAGCCATGGCCGTTGCCACCGTTGGTGTCGCGATGGGAGCAGACTCCGATGTCACGTCCGAAGCA
GCAGATGCTGTGATTTTGGATTCTTCCCTGGAACGTCTCGACGATCTGCTCCACATCAGTGCACGGATGCGTCGAATAGC
GTTGCAATCTGCGGGCGGTGGCATGGCGTTGAGTGTCGTAGGAATGATCCTCGCGGTATTTGGATTCTTGACGCCACTGA
TGGGTGCGATCTTCCAAGAGGTCATTGACGTGCTGGCTATCCTCAATTCCGCTCGGGTCGCAGTGCCACGCGGAGCGATT
AGTGATTTTGATACGCAAGAAAAAGTTTCTTAG

Upstream 100 bases:

>100_bases
GCAGCCAAATACGGCCAACGGCTCCTTGGAAATTTAAGGGGTCGTTGGCCTTATTATTTTAGGGAAAGCCCATCCTTGCC
TTGCCAAGGGAAGCCTGTAC

Downstream 100 bases:

>100_bases
CAGGGTAACCTAAATGTCGTGACATTTCGAGGCGGAAACACTGGCGCAAAGCACGCGGTCGTTGTTGGTTCTGGCCCCAA
TGGGTTGACCACGGCGGCGG

Product: hypothetical protein

Products: ADP; Orthophosphate. [C]

Alternate protein names: Metal-transporting ATPase Mta72 [H]

Number of amino acids: Translated: 650; Mature: 650

Protein sequence:

>650_residues
MLVSDIFMGDNGVMNKKLNTPNPWMLFIRSFDGIITVAALVAIAIHLILWLALDLDGLAKNWPLIAIVILGGIPLMWDVL
KSAIKTRGGADTLAAVSIITSVLLGEWLVAAIIVLMLSGGEALEEAASRRASGTLDALARRAPSTAHRLLGATILDGTEE
IAVEEITVGDLVAVLPHELCPVDGEIVAGHGTMDESYLTGEPYVVSKSKGSQAMSGAVNGDTPLTIVATKLAHDSRYAQI
VGVLHEAENNRPEMRRMADRLGAWYTVIALALGGLGWIISGDPVRFLAVVVVATPCPLLIAVPVAIIGAISLAARRGIIV
KNPGMLENASEVKTVMFDKTGTLTYGRPVITDIHTAPGVEEDTVLALAASVERYSRHPLADAIREGAKARELHLPDVVEV
SERPGQGLTGTVGEHLVRITNRRSTLEIDPDSKNYIPVTSSGMESVVLVDDKYAALIRLRDEPRASASEFIAHLPKKHKV
DKLMIISGDRASEVRYLADKVGIDEVHAEASPEDKLNIVNRHNEHGATMFLGDGINDAPAMAVATVGVAMGADSDVTSEA
ADAVILDSSLERLDDLLHISARMRRIALQSAGGGMALSVVGMILAVFGFLTPLMGAIFQEVIDVLAILNSARVAVPRGAI
SDFDTQEKVS

Sequences:

>Translated_650_residues
MLVSDIFMGDNGVMNKKLNTPNPWMLFIRSFDGIITVAALVAIAIHLILWLALDLDGLAKNWPLIAIVILGGIPLMWDVL
KSAIKTRGGADTLAAVSIITSVLLGEWLVAAIIVLMLSGGEALEEAASRRASGTLDALARRAPSTAHRLLGATILDGTEE
IAVEEITVGDLVAVLPHELCPVDGEIVAGHGTMDESYLTGEPYVVSKSKGSQAMSGAVNGDTPLTIVATKLAHDSRYAQI
VGVLHEAENNRPEMRRMADRLGAWYTVIALALGGLGWIISGDPVRFLAVVVVATPCPLLIAVPVAIIGAISLAARRGIIV
KNPGMLENASEVKTVMFDKTGTLTYGRPVITDIHTAPGVEEDTVLALAASVERYSRHPLADAIREGAKARELHLPDVVEV
SERPGQGLTGTVGEHLVRITNRRSTLEIDPDSKNYIPVTSSGMESVVLVDDKYAALIRLRDEPRASASEFIAHLPKKHKV
DKLMIISGDRASEVRYLADKVGIDEVHAEASPEDKLNIVNRHNEHGATMFLGDGINDAPAMAVATVGVAMGADSDVTSEA
ADAVILDSSLERLDDLLHISARMRRIALQSAGGGMALSVVGMILAVFGFLTPLMGAIFQEVIDVLAILNSARVAVPRGAI
SDFDTQEKVS
>Mature_650_residues
MLVSDIFMGDNGVMNKKLNTPNPWMLFIRSFDGIITVAALVAIAIHLILWLALDLDGLAKNWPLIAIVILGGIPLMWDVL
KSAIKTRGGADTLAAVSIITSVLLGEWLVAAIIVLMLSGGEALEEAASRRASGTLDALARRAPSTAHRLLGATILDGTEE
IAVEEITVGDLVAVLPHELCPVDGEIVAGHGTMDESYLTGEPYVVSKSKGSQAMSGAVNGDTPLTIVATKLAHDSRYAQI
VGVLHEAENNRPEMRRMADRLGAWYTVIALALGGLGWIISGDPVRFLAVVVVATPCPLLIAVPVAIIGAISLAARRGIIV
KNPGMLENASEVKTVMFDKTGTLTYGRPVITDIHTAPGVEEDTVLALAASVERYSRHPLADAIREGAKARELHLPDVVEV
SERPGQGLTGTVGEHLVRITNRRSTLEIDPDSKNYIPVTSSGMESVVLVDDKYAALIRLRDEPRASASEFIAHLPKKHKV
DKLMIISGDRASEVRYLADKVGIDEVHAEASPEDKLNIVNRHNEHGATMFLGDGINDAPAMAVATVGVAMGADSDVTSEA
ADAVILDSSLERLDDLLHISARMRRIALQSAGGGMALSVVGMILAVFGFLTPLMGAIFQEVIDVLAILNSARVAVPRGAI
SDFDTQEKVS

Specific function: Involved In Copper Efflux. [C]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=556, Percent_Identity=28.2374100719424, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI55743071, Length=510, Percent_Identity=30.1960784313725, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI55743073, Length=485, Percent_Identity=30.7216494845361, Blast_Score=171, Evalue=3e-42,
Organism=Escherichia coli, GI1786691, Length=608, Percent_Identity=30.4276315789474, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1789879, Length=565, Percent_Identity=32.3893805309734, Blast_Score=210, Evalue=3e-55,
Organism=Escherichia coli, GI1786914, Length=514, Percent_Identity=27.8210116731518, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17556548, Length=597, Percent_Identity=26.9681742043551, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320475, Length=519, Percent_Identity=28.7090558766859, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6319772, Length=580, Percent_Identity=27.4137931034483, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6321430, Length=557, Percent_Identity=22.9802513464991, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI221329854, Length=374, Percent_Identity=30.2139037433155, Blast_Score=136, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 69086; Mature: 69086

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSDIFMGDNGVMNKKLNTPNPWMLFIRSFDGIITVAALVAIAIHLILWLALDLDGLAK
CEECEEEECCCCCCCCCCCCCCCCEEEEHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHCC
NWPLIAIVILGGIPLMWDVLKSAIKTRGGADTLAAVSIITSVLLGEWLVAAIIVLMLSGG
CCCEEEEHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EALEEAASRRASGTLDALARRAPSTAHRLLGATILDGTEEIAVEEITVGDLVAVLPHELC
HHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHC
PVDGEIVAGHGTMDESYLTGEPYVVSKSKGSQAMSGAVNGDTPLTIVATKLAHDSRYAQI
CCCCEEEECCCCCCCCEECCCCEEEECCCCCHHHCCCCCCCCCEEEEEEHHHCCHHHHHH
VGVLHEAENNRPEMRRMADRLGAWYTVIALALGGLGWIISGDPVRFLAVVVVATPCPLLI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCHHHH
AVPVAIIGAISLAARRGIIVKNPGMLENASEVKTVMFDKTGTLTYGRPVITDIHTAPGVE
HHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHEEECCCCCEECCCCCEEECCCCCCCC
EDTVLALAASVERYSRHPLADAIREGAKARELHLPDVVEVSERPGQGLTGTVGEHLVRIT
CCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHH
NRRSTLEIDPDSKNYIPVTSSGMESVVLVDDKYAALIRLRDEPRASASEFIAHLPKKHKV
CCCCEEEECCCCCCEEEEECCCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHCCCCCCC
DKLMIISGDRASEVRYLADKVGIDEVHAEASPEDKLNIVNRHNEHGATMFLGDGINDAPA
CEEEEEECCCHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCHH
MAVATVGVAMGADSDVTSEAADAVILDSSLERLDDLLHISARMRRIALQSAGGGMALSVV
HHHHHHHHHCCCCCCCHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GMILAVFGFLTPLMGAIFQEVIDVLAILNSARVAVPRGAISDFDTQEKVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHCCC
>Mature Secondary Structure
MLVSDIFMGDNGVMNKKLNTPNPWMLFIRSFDGIITVAALVAIAIHLILWLALDLDGLAK
CEECEEEECCCCCCCCCCCCCCCCEEEEHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHCC
NWPLIAIVILGGIPLMWDVLKSAIKTRGGADTLAAVSIITSVLLGEWLVAAIIVLMLSGG
CCCEEEEHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EALEEAASRRASGTLDALARRAPSTAHRLLGATILDGTEEIAVEEITVGDLVAVLPHELC
HHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHC
PVDGEIVAGHGTMDESYLTGEPYVVSKSKGSQAMSGAVNGDTPLTIVATKLAHDSRYAQI
CCCCEEEECCCCCCCCEECCCCEEEECCCCCHHHCCCCCCCCCEEEEEEHHHCCHHHHHH
VGVLHEAENNRPEMRRMADRLGAWYTVIALALGGLGWIISGDPVRFLAVVVVATPCPLLI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCHHHH
AVPVAIIGAISLAARRGIIVKNPGMLENASEVKTVMFDKTGTLTYGRPVITDIHTAPGVE
HHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHEEECCCCCEECCCCCEEECCCCCCCC
EDTVLALAASVERYSRHPLADAIREGAKARELHLPDVVEVSERPGQGLTGTVGEHLVRIT
CCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHH
NRRSTLEIDPDSKNYIPVTSSGMESVVLVDDKYAALIRLRDEPRASASEFIAHLPKKHKV
CCCCEEEECCCCCCEEEEECCCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHCCCCCCC
DKLMIISGDRASEVRYLADKVGIDEVHAEASPEDKLNIVNRHNEHGATMFLGDGINDAPA
CEEEEEECCCHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCHH
MAVATVGVAMGADSDVTSEAADAVILDSSLERLDDLLHISARMRRIALQSAGGGMALSVV
HHHHHHHHHCCCCCCCHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GMILAVFGFLTPLMGAIFQEVIDVLAILNSARVAVPRGAISDFDTQEKVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]