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The map label for this gene is sdhB [H]

Identifier: 145294490

GI number: 145294490

Start: 498757

End: 499506

Strand: Direct

Name: sdhB [H]

Synonym: cgR_0445

Alternate gene names: 145294490

Gene position: 498757-499506 (Clockwise)

Preceding gene: 145294489

Following gene: 145294491

Centisome position: 15.05

GC content: 58.93

Gene sequence:

>750_bases
ATGAAACTTACACTTGAGATCTGGCGTCAGGCAGGCCCAACTGCAGAAGGCAAGTTCGAAACCGTACGGGTTGACGACGC
CGTCGCGCAGATGTCTATCCTGGAACTGCTAGACCACGTAAACAACAAGTTCATCGAAGAAGGCAAGGAACCATTCGCGT
TCGCCTCTGACTGCCGCGAAGGCATCTGTGGTACCTGTGGTCTCCTCGTGAACGGTCGCCCTCACGGCGCCGACCAGAAC
AAGCCTGCCTGTGCGCAGCGCCTGGTCAGCTACAAGGAAGGCGACACCCTTAAGATTGAGCCACTGCGCTCCGCCGCATA
CCCAGTGATCAAGGACATGGTCGTCGACCGCTCCGCACTGGACCGCGTCATGGAACAGGGTGGCTACGTGACCATCAACG
CAGGTACCGCACCTGACGCTGATACCCTCCACGTCAACCACGAAACCGCAGAACTCGCACTTGACCACGCAGCCTGCATC
GGCTGTGGTGCATGTGTCGCTGCCTGCCCTAACGGCGCAGCACACCTGTTCACCGGCGCAAAGCTTGTTCACCTCTCCCT
CCTCCCACTAGGTAAGGAAGAGCGCGGACTGCGTGCACGTAAGATGGTTGATGAAATGGAAACCAACTTCGGACACTGCT
CCCTCTACGGCGAGTGCGCAGACGTTTGCCCCGCAGGCATCCCACTGACCGCTGTGGCAGCTGTCACCAAAGAACGTGCG
CGTGCAGCTTTCCGAGGCAAAGACGACTAG

Upstream 100 bases:

>100_bases
TCGTCTCCGCATGGGAACCAGGCAAGAACGGAACCTTCGTCCGCCACGCAGAACCACTGTTCTTCGAATCCGTCCCACTG
CAGACAAGGAACTACAAGTA

Downstream 100 bases:

>100_bases
TCTTTAATCCAAGTAAGTACCGGTTCAGACAGTTAAACCAGAAAGACGAGTGAACACCATGTCCTCCGCGAAAAAGAAAC
CCGCACCGGAGCGTATGCAC

Product: succinate dehydrogenase/fumarate reductase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKLTLEIWRQAGPTAEGKFETVRVDDAVAQMSILELLDHVNNKFIEEGKEPFAFASDCREGICGTCGLLVNGRPHGADQN
KPACAQRLVSYKEGDTLKIEPLRSAAYPVIKDMVVDRSALDRVMEQGGYVTINAGTAPDADTLHVNHETAELALDHAACI
GCGACVAACPNGAAHLFTGAKLVHLSLLPLGKEERGLRARKMVDEMETNFGHCSLYGECADVCPAGIPLTAVAAVTKERA
RAAFRGKDD

Sequences:

>Translated_249_residues
MKLTLEIWRQAGPTAEGKFETVRVDDAVAQMSILELLDHVNNKFIEEGKEPFAFASDCREGICGTCGLLVNGRPHGADQN
KPACAQRLVSYKEGDTLKIEPLRSAAYPVIKDMVVDRSALDRVMEQGGYVTINAGTAPDADTLHVNHETAELALDHAACI
GCGACVAACPNGAAHLFTGAKLVHLSLLPLGKEERGLRARKMVDEMETNFGHCSLYGECADVCPAGIPLTAVAAVTKERA
RAAFRGKDD
>Mature_249_residues
MKLTLEIWRQAGPTAEGKFETVRVDDAVAQMSILELLDHVNNKFIEEGKEPFAFASDCREGICGTCGLLVNGRPHGADQN
KPACAQRLVSYKEGDTLKIEPLRSAAYPVIKDMVVDRSALDRVMEQGGYVTINAGTAPDADTLHVNHETAELALDHAACI
GCGACVAACPNGAAHLFTGAKLVHLSLLPLGKEERGLRARKMVDEMETNFGHCSLYGECADVCPAGIPLTAVAAVTKERA
RAAFRGKDD

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790596, Length=202, Percent_Identity=27.7227722772277, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 26677; Mature: 26677

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00197 2FE2S_FER_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTLEIWRQAGPTAEGKFETVRVDDAVAQMSILELLDHVNNKFIEEGKEPFAFASDCRE
CEEEHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
GICGTCGLLVNGRPHGADQNKPACAQRLVSYKEGDTLKIEPLRSAAYPVIKDMVVDRSAL
CCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCHHHH
DRVMEQGGYVTINAGTAPDADTLHVNHETAELALDHAACIGCGACVAACPNGAAHLFTGA
HHHHHCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
KLVHLSLLPLGKEERGLRARKMVDEMETNFGHCSLYGECADVCPAGIPLTAVAAVTKERA
EEEEEEECCCCCHHHCHHHHHHHHHHHCCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHH
RAAFRGKDD
HHHCCCCCC
>Mature Secondary Structure
MKLTLEIWRQAGPTAEGKFETVRVDDAVAQMSILELLDHVNNKFIEEGKEPFAFASDCRE
CEEEHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
GICGTCGLLVNGRPHGADQNKPACAQRLVSYKEGDTLKIEPLRSAAYPVIKDMVVDRSAL
CCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCHHHH
DRVMEQGGYVTINAGTAPDADTLHVNHETAELALDHAACIGCGACVAACPNGAAHLFTGA
HHHHHCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
KLVHLSLLPLGKEERGLRARKMVDEMETNFGHCSLYGECADVCPAGIPLTAVAAVTKERA
EEEEEEECCCCCHHHCHHHHHHHHHHHCCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHH
RAAFRGKDD
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]