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The map label for this gene is yngJ [H]

Identifier: 145294419

GI number: 145294419

Start: 409224

End: 410420

Strand: Direct

Name: yngJ [H]

Synonym: cgR_0374

Alternate gene names: 145294419

Gene position: 409224-410420 (Clockwise)

Preceding gene: 145294418

Following gene: 145294420

Centisome position: 12.35

GC content: 54.14

Gene sequence:

>1197_bases
ATGCGTGATCCCATTCAAGGTGCTGTTATTCCTTCTGATCTTTTTGGTTTCGCAGAAGTTCTCACCGAAGCCGAACGCGC
AGTTCTTCTGGAAACCCGCAGGGTGCTTGAGGAAGAGGTGAAGCCTTATATTAATGAGGCCTGGGATAAGGCAGTTTTCC
CCAATGCGATTATGCAGCCCCTCCAAGATCTGCAATTGCTTGATCCGCCTGCACTGCGGGAAGCAGGGGAGTCGGTTCGA
GACATTTTCACTGGTTTCCGCAATTTTGAACTCGCGCGCTGTGACATCAATGTTGGTACCTATTACAACGCATCTGCTGG
TCTCTTCCGAACGGCCTGCATGGTTGGTGGCTCCCCGGAGCAGGCGCAGCGATTGGATGCGCAGATCAAATCTGGTGAGG
TCAAGGGCGTTTTTGCACTGACGGAACCTGATCATGGCTCTGATATCGCAGGTGGTCTGGCAACCACGGCCACTAAGGAT
GCAGACACCGGCGAGTGGATTATCAATGGTGAAAAACGGTGGATCGGTGGTGCTTCCACTGCTGATTTGATCGCTACCTT
CGCCAGGGATACAGCCGATAACCAGGTGAAATGCTTCCTCGTGGCACCTCAGGCAGAGGGCGTGTCCATGGAGATTATTG
ATCGCAAAGCCTCACTGCGCATCATGCAAAATGCACACATTACCTATAACAATGTCCGGGTGTCTGAGGATGCGCGGCTG
CACAACATCAATTCTTTCAAGGATGTTTCGGAATGCCTGCGCCGTATGCGTTCCGATGTGGCGTGGATGGCGGTCGGCGC
GCAGGCAGGTGCCTATGAAGCAGCCGTGAAGTATGTGCGCAGCAGGGAACAGTTTGGCCGTCCGATCGCGGGGTTCCAGT
TGATTCAGGAAAAGCTCGCGCTCATGCTGGGCAATCTCACGGCGTCGCTGGGCATGATGGTCAAACTCACCGAGCAGCAG
CAGGCGGGAATTTTCAAAGAGGAAAACTCCGCGCTGGCGAAAATGTTTACCTCGCTCAAACTTCGGGAGACCGCTAGTTG
GGCGCGGGAAATCTGCGGAGGCAACGGCATCATTTTGGACAACGATGTCGCCCGGTTCCACGCCGATGCAGAAGCCGTCT
ATTCATATGAAGGCACCCACGAAATCAATGCACTCATCGTTGGTCGCGCCATCACGGGCGTCAGCGCTTTTATCTAA

Upstream 100 bases:

>100_bases
GATGAGGTTCGTCCGGGGATCCTCAAAGACAATGCGGTGAAGGTACTTGGCCTAGCCGCTAGCACTGAGCGCGGATCTCA
AGCAGAAAAGGCCGTGCAAC

Downstream 100 bases:

>100_bases
CACACTTTTAAGGAGAACATCATGACTACTTCCACCACCCCAAACACCATCATTTCTTTCGAAGACGCACCAACCCTCAC
CGGCCAGGACCTGGGCTTTT

Product: hypothetical protein

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MRDPIQGAVIPSDLFGFAEVLTEAERAVLLETRRVLEEEVKPYINEAWDKAVFPNAIMQPLQDLQLLDPPALREAGESVR
DIFTGFRNFELARCDINVGTYYNASAGLFRTACMVGGSPEQAQRLDAQIKSGEVKGVFALTEPDHGSDIAGGLATTATKD
ADTGEWIINGEKRWIGGASTADLIATFARDTADNQVKCFLVAPQAEGVSMEIIDRKASLRIMQNAHITYNNVRVSEDARL
HNINSFKDVSECLRRMRSDVAWMAVGAQAGAYEAAVKYVRSREQFGRPIAGFQLIQEKLALMLGNLTASLGMMVKLTEQQ
QAGIFKEENSALAKMFTSLKLRETASWAREICGGNGIILDNDVARFHADAEAVYSYEGTHEINALIVGRAITGVSAFI

Sequences:

>Translated_398_residues
MRDPIQGAVIPSDLFGFAEVLTEAERAVLLETRRVLEEEVKPYINEAWDKAVFPNAIMQPLQDLQLLDPPALREAGESVR
DIFTGFRNFELARCDINVGTYYNASAGLFRTACMVGGSPEQAQRLDAQIKSGEVKGVFALTEPDHGSDIAGGLATTATKD
ADTGEWIINGEKRWIGGASTADLIATFARDTADNQVKCFLVAPQAEGVSMEIIDRKASLRIMQNAHITYNNVRVSEDARL
HNINSFKDVSECLRRMRSDVAWMAVGAQAGAYEAAVKYVRSREQFGRPIAGFQLIQEKLALMLGNLTASLGMMVKLTEQQ
QAGIFKEENSALAKMFTSLKLRETASWAREICGGNGIILDNDVARFHADAEAVYSYEGTHEINALIVGRAITGVSAFI
>Mature_398_residues
MRDPIQGAVIPSDLFGFAEVLTEAERAVLLETRRVLEEEVKPYINEAWDKAVFPNAIMQPLQDLQLLDPPALREAGESVR
DIFTGFRNFELARCDINVGTYYNASAGLFRTACMVGGSPEQAQRLDAQIKSGEVKGVFALTEPDHGSDIAGGLATTATKD
ADTGEWIINGEKRWIGGASTADLIATFARDTADNQVKCFLVAPQAEGVSMEIIDRKASLRIMQNAHITYNNVRVSEDARL
HNINSFKDVSECLRRMRSDVAWMAVGAQAGAYEAAVKYVRSREQFGRPIAGFQLIQEKLALMLGNLTASLGMMVKLTEQQ
QAGIFKEENSALAKMFTSLKLRETASWAREICGGNGIILDNDVARFHADAEAVYSYEGTHEINALIVGRAITGVSAFI

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=391, Percent_Identity=34.0153452685422, Blast_Score=178, Evalue=8e-45,
Organism=Homo sapiens, GI7669494, Length=371, Percent_Identity=31.8059299191375, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4557233, Length=374, Percent_Identity=28.8770053475936, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI4557235, Length=405, Percent_Identity=28.1481481481481, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI76496475, Length=405, Percent_Identity=28.1481481481481, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI4501857, Length=373, Percent_Identity=24.9329758713137, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4501859, Length=386, Percent_Identity=25.3886010362694, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4557231, Length=383, Percent_Identity=25.3263707571802, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI187960098, Length=383, Percent_Identity=25.3263707571802, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI21361497, Length=296, Percent_Identity=26.3513513513513, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI226958412, Length=387, Percent_Identity=24.5478036175711, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI226958414, Length=315, Percent_Identity=25.7142857142857, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI7656849, Length=282, Percent_Identity=24.822695035461, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI218563752, Length=260, Percent_Identity=27.6923076923077, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786223, Length=361, Percent_Identity=28.2548476454294, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI87081958, Length=281, Percent_Identity=29.1814946619217, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=386, Percent_Identity=31.8652849740933, Blast_Score=204, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17508101, Length=389, Percent_Identity=28.0205655526992, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17538396, Length=393, Percent_Identity=27.2264631043257, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17506239, Length=377, Percent_Identity=25.4641909814324, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71990804, Length=255, Percent_Identity=28.2352941176471, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=285, Percent_Identity=28.7719298245614, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17569725, Length=286, Percent_Identity=27.972027972028, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71985184, Length=413, Percent_Identity=23.4866828087167, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71985192, Length=341, Percent_Identity=23.4604105571848, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=261, Percent_Identity=28.3524904214559, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=212, Percent_Identity=28.3018867924528, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=268, Percent_Identity=27.6119402985075, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=281, Percent_Identity=25.9786476868327, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920834, Length=387, Percent_Identity=33.8501291989664, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24660351, Length=385, Percent_Identity=29.0909090909091, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24666513, Length=385, Percent_Identity=25.974025974026, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281363737, Length=413, Percent_Identity=24.9394673123487, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21356377, Length=389, Percent_Identity=26.7352185089974, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24646207, Length=382, Percent_Identity=27.2251308900524, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355753, Length=315, Percent_Identity=26.984126984127, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221473076, Length=348, Percent_Identity=25, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI45550141, Length=348, Percent_Identity=25, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 43588; Mature: 43588

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDPIQGAVIPSDLFGFAEVLTEAERAVLLETRRVLEEEVKPYINEAWDKAVFPNAIMQP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LQDLQLLDPPALREAGESVRDIFTGFRNFELARCDINVGTYYNASAGLFRTACMVGGSPE
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCEECCCCHHHHHHHHCCCCHH
QAQRLDAQIKSGEVKGVFALTEPDHGSDIAGGLATTATKDADTGEWIINGEKRWIGGAST
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHCCCCCCCCCCEEECCCEEEECCCCH
ADLIATFARDTADNQVKCFLVAPQAEGVSMEIIDRKASLRIMQNAHITYNNVRVSEDARL
HHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCHHHEEEEECCCEEECCEEECCCCCC
HNINSFKDVSECLRRMRSDVAWMAVGAQAGAYEAAVKYVRSREQFGRPIAGFQLIQEKLA
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LMLGNLTASLGMMVKLTEQQQAGIFKEENSALAKMFTSLKLRETASWAREICGGNGIILD
HHHHHHHHHHCCEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
NDVARFHADAEAVYSYEGTHEINALIVGRAITGVSAFI
CCHHHHHCCHHHHEECCCCCCEEEEEEEHHHHHHHHCC
>Mature Secondary Structure
MRDPIQGAVIPSDLFGFAEVLTEAERAVLLETRRVLEEEVKPYINEAWDKAVFPNAIMQP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LQDLQLLDPPALREAGESVRDIFTGFRNFELARCDINVGTYYNASAGLFRTACMVGGSPE
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCEECCCCHHHHHHHHCCCCHH
QAQRLDAQIKSGEVKGVFALTEPDHGSDIAGGLATTATKDADTGEWIINGEKRWIGGAST
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHCCCCCCCCCCEEECCCEEEECCCCH
ADLIATFARDTADNQVKCFLVAPQAEGVSMEIIDRKASLRIMQNAHITYNNVRVSEDARL
HHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCHHHEEEEECCCEEECCEEECCCCCC
HNINSFKDVSECLRRMRSDVAWMAVGAQAGAYEAAVKYVRSREQFGRPIAGFQLIQEKLA
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LMLGNLTASLGMMVKLTEQQQAGIFKEENSALAKMFTSLKLRETASWAREICGGNGIILD
HHHHHHHHHHCCEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
NDVARFHADAEAVYSYEGTHEINALIVGRAITGVSAFI
CCHHHHHCCHHHHEECCCCCCEEEEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]