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The map label for this gene is yybE [H]

Identifier: 145294396

GI number: 145294396

Start: 387519

End: 388280

Strand: Direct

Name: yybE [H]

Synonym: cgR_0351

Alternate gene names: 145294396

Gene position: 387519-388280 (Clockwise)

Preceding gene: 145294393

Following gene: 145294403

Centisome position: 11.69

GC content: 53.02

Gene sequence:

>762_bases
GTGCGCTTAGTTGAACGCCGGGGTCGGGGAATAGAACTTACTGCTGAAGGCGCAGCTTTAGCCGATGCAGCAATTGAAGC
ACTATCAGTGTTTCAACCTGCATTAGAAAATCTTTTGGGAGATAGGAATTTAAGGCCAGTTCGGCTGGGCACGCTGCGTT
CCATCGCCGGAGAGCTTGGTCCATTAATTGGCAGAAGTAGTTTGCCCACCAATGTCAGCATCACAGAAGGCTCGTCGGAT
GATTTGCTTCGGCTGATTGAGCGCGGGGAGATCGACGCAGCAATAATTGGCCCGAAGCCGACAGATACCCGATTCACGTG
GCAGTTTATCCGCGACCAGGAGATTGTGTTGGTGGTGCCTAAAGATCACAGGCTCAGCCACCATGATGCGGTTGAATTGA
AAGAAGTGGAAGGCGAACACTTTGTCGCCATGACTAATAAATACACCACGCGGGATCTTGCCGATCAGCTGTGTGCAGAG
GCCGGAATCTCCCCAACGATTTCCGTGGAATCAGATTCTTCCTACACGTTGCGCACCTACGTGGCATCCGGATTAGGTCT
GTGCATTTTGCCGGAAATTATGGCAGATTTAGATCCTAATATTGCAACGGTGCAGGTTAGGCGACCCAACGGGGAGTTAG
CCACCAGAGAGATCGGCTTGGTTAAGATGGCAGGGCGCCCGCTGCCGACGCAGGTCAACGCGACCTTGCGCATGCTGCTC
GCACGCCCCATTAAAGCTTTTCGACGCCCACCTTCGCAATAG

Upstream 100 bases:

>100_bases
GCTACGCAGGGGAGAAACCATCACGCAAACAGCAAAACGTTTAGGTATGTCTCAGCCCGCATTGTCGCGCACCATTTCAA
GGTGGGAGTCTGAACTATCG

Downstream 100 bases:

>100_bases
TTTCCTCCACGCCGACATTATCTACGCACCATCCGGTGTAGTCGGTGTCCAACCCCCGAAGTAGCCCAATCAAAGTGTTG
CCGGGGGAGACCTGTATCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MRLVERRGRGIELTAEGAALADAAIEALSVFQPALENLLGDRNLRPVRLGTLRSIAGELGPLIGRSSLPTNVSITEGSSD
DLLRLIERGEIDAAIIGPKPTDTRFTWQFIRDQEIVLVVPKDHRLSHHDAVELKEVEGEHFVAMTNKYTTRDLADQLCAE
AGISPTISVESDSSYTLRTYVASGLGLCILPEIMADLDPNIATVQVRRPNGELATREIGLVKMAGRPLPTQVNATLRMLL
ARPIKAFRRPPSQ

Sequences:

>Translated_253_residues
MRLVERRGRGIELTAEGAALADAAIEALSVFQPALENLLGDRNLRPVRLGTLRSIAGELGPLIGRSSLPTNVSITEGSSD
DLLRLIERGEIDAAIIGPKPTDTRFTWQFIRDQEIVLVVPKDHRLSHHDAVELKEVEGEHFVAMTNKYTTRDLADQLCAE
AGISPTISVESDSSYTLRTYVASGLGLCILPEIMADLDPNIATVQVRRPNGELATREIGLVKMAGRPLPTQVNATLRMLL
ARPIKAFRRPPSQ
>Mature_253_residues
MRLVERRGRGIELTAEGAALADAAIEALSVFQPALENLLGDRNLRPVRLGTLRSIAGELGPLIGRSSLPTNVSITEGSSD
DLLRLIERGEIDAAIIGPKPTDTRFTWQFIRDQEIVLVVPKDHRLSHHDAVELKEVEGEHFVAMTNKYTTRDLADQLCAE
AGISPTISVESDSSYTLRTYVASGLGLCILPEIMADLDPNIATVQVRRPNGELATREIGLVKMAGRPLPTQVNATLRMLL
ARPIKAFRRPPSQ

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=249, Percent_Identity=22.8915662650602, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI2367136, Length=116, Percent_Identity=29.3103448275862, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 27674; Mature: 27674

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVERRGRGIELTAEGAALADAAIEALSVFQPALENLLGDRNLRPVRLGTLRSIAGELG
CCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHH
PLIGRSSLPTNVSITEGSSDDLLRLIERGEIDAAIIGPKPTDTRFTWQFIRDQEIVLVVP
HHCCCCCCCCEEEEECCCHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCEEEEEEC
KDHRLSHHDAVELKEVEGEHFVAMTNKYTTRDLADQLCAEAGISPTISVESDSSYTLRTY
CCCCCCCCCCCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCEEHHHH
VASGLGLCILPEIMADLDPNIATVQVRRPNGELATREIGLVKMAGRPLPTQVNATLRMLL
HHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEHHEECEEEECCCCCCHHHHHHHHHHH
ARPIKAFRRPPSQ
HHHHHHHCCCCCC
>Mature Secondary Structure
MRLVERRGRGIELTAEGAALADAAIEALSVFQPALENLLGDRNLRPVRLGTLRSIAGELG
CCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHH
PLIGRSSLPTNVSITEGSSDDLLRLIERGEIDAAIIGPKPTDTRFTWQFIRDQEIVLVVP
HHCCCCCCCCEEEEECCCHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCEEEEEEC
KDHRLSHHDAVELKEVEGEHFVAMTNKYTTRDLADQLCAEAGISPTISVESDSSYTLRTY
CCCCCCCCCCCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCEEHHHH
VASGLGLCILPEIMADLDPNIATVQVRRPNGELATREIGLVKMAGRPLPTQVNATLRMLL
HHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEHHEECEEEECCCCCCHHHHHHHHHHH
ARPIKAFRRPPSQ
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]