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The map label for this gene is katA [H]

Identifier: 145294377

GI number: 145294377

Start: 372428

End: 373978

Strand: Direct

Name: katA [H]

Synonym: cgR_0332

Alternate gene names: 145294377

Gene position: 372428-373978 (Clockwise)

Preceding gene: 145294375

Following gene: 145294378

Centisome position: 11.24

GC content: 56.93

Gene sequence:

>1551_bases
ATGTCTGAGAAGTCAGCAGCAGACCAGATCGTAGATCGCGGAATGCGTCCAAAGCTTTCTGGAAACACCACCCGCCACAA
CGGAGCACCAGTTCCATCTGAGAACATCTCCGCAACCGCAGGCCCACAGGGCCCAAACGTTCTCAATGACATTCACCTCA
TTGAAAAGCTCGCACACTTTAACCGCGAGAACGTTCCAGAGCGTATCCCTCACGCAAAGGGCCACGGCGCTTTCGGTGAG
CTGCACATCACCGAGGACGTATCCGAATACACCAAGGCAGACCTGTTCCAGCCTGGTAAGGTCACCCCGCTGGCTGTTCG
CTTCTCCACTGTTGCTGGTGAGCAGGGCTCCCCAGATACCTGGCGCGACGTCCACGGCTTCGCTCTTCGCTTCTACACCG
AAGAGGGCAACTACGACATCGTGGGTAACAACACCCCAACCTTCTTCCTTCGTGACGGCATGAAGTTCCCGGACTTCATC
CACTCACAGAAGCGTCTCAACAAGAACGGTCTGCGCGATGCAGACATGCAGTGGGATTTCTGGACCCGCGCACCTGAATC
TGCACACCAGGTGACCTACCTGATGGGTGACCGCGGTACCCCTAAGACCTCCCGCCACCAGGACGGCTTCGGCTCCCACA
CCTTCCAGTGGATCAACGCTGAAGGTAAGCCAGTTTGGGTTAAGTACCACTTCAAGACCCGCCAGGGCTGGGATTGCTTC
ACCGATGCAGAAGCAGCAAAGGTTGCAGGCGAGAACGCTGACTACCAGCGCGAAGACCTCTACAACGCTATTGAAAACGG
CGACTTCCCAATCTGGGACGTCAAGGTTCAGATCATGCCTTTCGAGGATGCAGAGAACTACCGCTGGAACCCATTCGATC
TGACCAAGACCTGGTCTCAGAAGGATTACCCACTGATCCCAGTCGGTTACTTCATCCTGAACCGCAACCCACGCAACTTC
TTCGCTCAGATCGAGCAGCTTGCACTGGATCCAGGCAACATCGTTCCTGGCGTCGGCCTGTCCCCAGACCGCATGCTCCA
GGCACGTGTCTTCGCATACGCGGACCAGCAGCGTTACCGCATCGGCGCTAACTACCGCGACCTGCCAGTGAACCGTCCAA
TCAACGAGGTCAACACCTACAGCCGCGAAGGTTCCATGCAGTACATCTTCGACGCTGAGGGCGAGCCTTCCTACAGCCCT
AACCGCTACGACAAGGGCGCAGGCTACCTGGACAACGGTACGGATTCCTCCTCCAACCACACCTCCTACGGCCAGGCTGA
TGACATCTACGTCAACCCAGACCCACACGGCACCGACTTGGTTCGTGCTGCTTACGTCAAGCACCAGGATGATGACGACT
TCATCCAGCCAGGCATCCTATACCGCGAGGTCCTGGATGAGGGCGAGAAGGAGCGATTGGCAGACAACATCTCCAACGCA
ATGCAGGGCATCTCTGAGGCAACCGAGCCACGCGTCTACGACTACTGGAACAACGTTGATGAGAACCTCGGCGCTCGCGT
CAAGGAGCTTTACCTCCAGAAGAAGGCTTAA

Upstream 100 bases:

>100_bases
ACGTAAGGGCTGATTATTTGGTGGCGCGAAGCGACATTCTGATGTAGACTATCAATCAGACTTAATCCATAGGTAACCCT
CATAAAAGGAAGGAATGCTA

Downstream 100 bases:

>100_bases
GTCCTTCTGATTTAAAATGAGGGCCTATCCACCAATGGTGGATAGGCCCTCATTCGACTTTGAAGCTATTGAGAGGAAAT
TAGCTAGACAGCAGATCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MSEKSAADQIVDRGMRPKLSGNTTRHNGAPVPSENISATAGPQGPNVLNDIHLIEKLAHFNRENVPERIPHAKGHGAFGE
LHITEDVSEYTKADLFQPGKVTPLAVRFSTVAGEQGSPDTWRDVHGFALRFYTEEGNYDIVGNNTPTFFLRDGMKFPDFI
HSQKRLNKNGLRDADMQWDFWTRAPESAHQVTYLMGDRGTPKTSRHQDGFGSHTFQWINAEGKPVWVKYHFKTRQGWDCF
TDAEAAKVAGENADYQREDLYNAIENGDFPIWDVKVQIMPFEDAENYRWNPFDLTKTWSQKDYPLIPVGYFILNRNPRNF
FAQIEQLALDPGNIVPGVGLSPDRMLQARVFAYADQQRYRIGANYRDLPVNRPINEVNTYSREGSMQYIFDAEGEPSYSP
NRYDKGAGYLDNGTDSSSNHTSYGQADDIYVNPDPHGTDLVRAAYVKHQDDDDFIQPGILYREVLDEGEKERLADNISNA
MQGISEATEPRVYDYWNNVDENLGARVKELYLQKKA

Sequences:

>Translated_516_residues
MSEKSAADQIVDRGMRPKLSGNTTRHNGAPVPSENISATAGPQGPNVLNDIHLIEKLAHFNRENVPERIPHAKGHGAFGE
LHITEDVSEYTKADLFQPGKVTPLAVRFSTVAGEQGSPDTWRDVHGFALRFYTEEGNYDIVGNNTPTFFLRDGMKFPDFI
HSQKRLNKNGLRDADMQWDFWTRAPESAHQVTYLMGDRGTPKTSRHQDGFGSHTFQWINAEGKPVWVKYHFKTRQGWDCF
TDAEAAKVAGENADYQREDLYNAIENGDFPIWDVKVQIMPFEDAENYRWNPFDLTKTWSQKDYPLIPVGYFILNRNPRNF
FAQIEQLALDPGNIVPGVGLSPDRMLQARVFAYADQQRYRIGANYRDLPVNRPINEVNTYSREGSMQYIFDAEGEPSYSP
NRYDKGAGYLDNGTDSSSNHTSYGQADDIYVNPDPHGTDLVRAAYVKHQDDDDFIQPGILYREVLDEGEKERLADNISNA
MQGISEATEPRVYDYWNNVDENLGARVKELYLQKKA
>Mature_515_residues
SEKSAADQIVDRGMRPKLSGNTTRHNGAPVPSENISATAGPQGPNVLNDIHLIEKLAHFNRENVPERIPHAKGHGAFGEL
HITEDVSEYTKADLFQPGKVTPLAVRFSTVAGEQGSPDTWRDVHGFALRFYTEEGNYDIVGNNTPTFFLRDGMKFPDFIH
SQKRLNKNGLRDADMQWDFWTRAPESAHQVTYLMGDRGTPKTSRHQDGFGSHTFQWINAEGKPVWVKYHFKTRQGWDCFT
DAEAAKVAGENADYQREDLYNAIENGDFPIWDVKVQIMPFEDAENYRWNPFDLTKTWSQKDYPLIPVGYFILNRNPRNFF
AQIEQLALDPGNIVPGVGLSPDRMLQARVFAYADQQRYRIGANYRDLPVNRPINEVNTYSREGSMQYIFDAEGEPSYSPN
RYDKGAGYLDNGTDSSSNHTSYGQADDIYVNPDPHGTDLVRAAYVKHQDDDDFIQPGILYREVLDEGEKERLADNISNAM
QGISEATEPRVYDYWNNVDENLGARVKELYLQKKA

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=488, Percent_Identity=44.0573770491803, Blast_Score=433, Evalue=1e-121,
Organism=Escherichia coli, GI48994891, Length=384, Percent_Identity=42.96875, Blast_Score=317, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI71998444, Length=495, Percent_Identity=44.8484848484849, Blast_Score=443, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI25151141, Length=516, Percent_Identity=43.2170542635659, Blast_Score=426, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI25147792, Length=495, Percent_Identity=43.4343434343434, Blast_Score=423, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6320462, Length=501, Percent_Identity=42.315369261477, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321525, Length=511, Percent_Identity=37.7690802348337, Blast_Score=328, Evalue=1e-90,
Organism=Drosophila melanogaster, GI17981717, Length=516, Percent_Identity=43.2170542635659, Blast_Score=442, Evalue=1e-124,
Organism=Drosophila melanogaster, GI19920968, Length=512, Percent_Identity=38.0859375, Blast_Score=384, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 58695; Mature: 58564

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKSAADQIVDRGMRPKLSGNTTRHNGAPVPSENISATAGPQGPNVLNDIHLIEKLAHF
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
NRENVPERIPHAKGHGAFGELHITEDVSEYTKADLFQPGKVTPLAVRFSTVAGEQGSPDT
CCCCCHHHCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCH
WRDVHGFALRFYTEEGNYDIVGNNTPTFFLRDGMKFPDFIHSQKRLNKNGLRDADMQWDF
HHHHCCEEEEEEEECCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHH
WTRAPESAHQVTYLMGDRGTPKTSRHQDGFGSHTFQWINAEGKPVWVKYHFKTRQGWDCF
HCCCCCCHHEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCC
TDAEAAKVAGENADYQREDLYNAIENGDFPIWDVKVQIMPFEDAENYRWNPFDLTKTWSQ
CCCHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCC
KDYPLIPVGYFILNRNPRNFFAQIEQLALDPGNIVPGVGLSPDRMLQARVFAYADQQRYR
CCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEE
IGANYRDLPVNRPINEVNTYSREGSMQYIFDAEGEPSYSPNRYDKGAGYLDNGTDSSSNH
ECCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TSYGQADDIYVNPDPHGTDLVRAAYVKHQDDDDFIQPGILYREVLDEGEKERLADNISNA
CCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHH
MQGISEATEPRVYDYWNNVDENLGARVKELYLQKKA
HHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEKSAADQIVDRGMRPKLSGNTTRHNGAPVPSENISATAGPQGPNVLNDIHLIEKLAHF
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
NRENVPERIPHAKGHGAFGELHITEDVSEYTKADLFQPGKVTPLAVRFSTVAGEQGSPDT
CCCCCHHHCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCH
WRDVHGFALRFYTEEGNYDIVGNNTPTFFLRDGMKFPDFIHSQKRLNKNGLRDADMQWDF
HHHHCCEEEEEEEECCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHH
WTRAPESAHQVTYLMGDRGTPKTSRHQDGFGSHTFQWINAEGKPVWVKYHFKTRQGWDCF
HCCCCCCHHEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCC
TDAEAAKVAGENADYQREDLYNAIENGDFPIWDVKVQIMPFEDAENYRWNPFDLTKTWSQ
CCCHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCC
KDYPLIPVGYFILNRNPRNFFAQIEQLALDPGNIVPGVGLSPDRMLQARVFAYADQQRYR
CCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEE
IGANYRDLPVNRPINEVNTYSREGSMQYIFDAEGEPSYSPNRYDKGAGYLDNGTDSSSNH
ECCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TSYGQADDIYVNPDPHGTDLVRAAYVKHQDDDDFIQPGILYREVLDEGEKERLADNISNA
CCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHH
MQGISEATEPRVYDYWNNVDENLGARVKELYLQKKA
HHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1426241; 12454454 [H]