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The map label for this gene is sdcS [H]

Identifier: 145294344

GI number: 145294344

Start: 325415

End: 326998

Strand: Direct

Name: sdcS [H]

Synonym: cgR_0299

Alternate gene names: 145294344

Gene position: 325415-326998 (Clockwise)

Preceding gene: 145294343

Following gene: 145294346

Centisome position: 9.82

GC content: 52.27

Gene sequence:

>1584_bases
ATGAGCACACCTGACATTAAAGAAGGCTCGGCAGAATCACCGGGCGAAGTAATGGTCGTTGGAGACAGGCGAGAGTGGCG
TCGACAAGCAACCGGTATCATTGCCGGCCTCGTCCTAGCCGCCCTGGTCTATCTTCTCTTCCCCTCGAACTCCGTGGAAA
CCGTCATGCAATCCAGTGGCGTCGATCCAGAAACTGAATACACCAACAACGCGATGCGTCTTACTGCTGCAGTCACAATC
TTGATGGCAGTATGGTGGATGACAGAAGCAATCCCACTAGCAGCAACCGCACTTATCCCGTTGGTTGCATTCCCCGCTTT
CCAGGTTGTGGACTTTGGGAAGGCAGCAGCTCCGTATGCCAACCCTACGATCTTCCTCTTCTTGGGCGGCTTTCTCATGG
CACTTGGCCTGCAGAAATGGAACCTACACCGACGCATGGCTCTAGCGGTCGTGCTAGCTGTTGGTACTAAGCCAAAGCAA
TTGGTCTTGGGTTTTATGGTTGCAACTGGATTTTTGTCCATGTGGGTGTCTAACACTGCAACGGCCGTGGTTATGTTACC
GATCGGTATGTCGGTACTAGCACTGACCGCTGAGACTGTGGGCGGAATGAAAAACCAAAAGAAATTCGCCACTGGACTCA
TGCTGTCCATTGCTTATTCTGCTTCCATCGGTTCACTCGGCACCTTAATTGGCACGCCACCCAATGCCTTGCTTGCTGCG
TATATGTCTGAATCGCATGATATCCACATCGGATTTGGTCAGTGGATGATTCTGGGTGTACCAATTGCTGTCGTCTTCAC
CATCATCGCGTGGCTTGTGTTGACCACCGTGTTCAAGCCAGAAATGAAAGAAATCCCTGGCGGACGTGAACTGATCAAAC
GTGAAATCGCTGAAATGGGGCCGTGGACTGCACCTCAGGTCACAGTGGGTGTTATTTTTGCGGCAGCTGCACTGGCTTGG
GTCTTCATTCCATTAACTCTAGATTGGACCGGTTCCCAGCTCTCTATCAATGACTCCCTCATTGGCATCGCTGCCGGCCT
GCTGATGTTTATCGTTCCCGCTAACTTTAAAACCGGCGAACGCATTCTTGATTGGCGTACTGCAGGCGAACTTCCATGGG
ATGTTCTCTTGCTTTTTGGTGGCGGACTTTCACTTTCTGCGATGTTTACCAGCACGGGACTTTCCCTATGGATCGGTGAA
CTAGCGAAGGGACTTGATGCCCTTCCAATCTTCATTCTCATCTTCGCCATTGCTGTCCTGGTGTTGTTCCTGACCGAGTT
CACCTCCAACACCGCAACAGCGGCAACCTTCCTGCCAATCATGGGTGGCGTCGCCGTAGGTATCGGACTGACCGCAGGTG
GCGAGCAGAATGTTCTGCTGCTGACCATCCCAGTCGCACTGTCCGCAACCTGTGCGTTCATGCTTCCAGTGGCAACGCCT
CCAAACGCGATTGCATTCGGCTCCGGCTACATTAAGATCGGCGAAATGGTCAAGGGTGGTCTGTGGCTGAACATCATCGC
AGTCATCCTCATTTCGATCTCCACCTACTTCGTAGCGATCCCACTCTTTGGCATCATGCTTTAA

Upstream 100 bases:

>100_bases
TCGTTGGCTTACATGGTCATTGATGACCGGGCTGAATATGTGAGAAAATCCATCCCTTCTTTAAGCAAGGGAGTGAATTA
CAGAAAAGGATTGTTCAGCA

Downstream 100 bases:

>100_bases
AAGTTAACAGGCCCGCAGTCAATGTAAATGGCGTTGAACTGCGGGTTTGTTGTTCTTTCTGAAGCTGTGTAAAGTAATCG
TCGTTGCAGAGAACGCCACA

Product: hypothetical protein

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MSTPDIKEGSAESPGEVMVVGDRREWRRQATGIIAGLVLAALVYLLFPSNSVETVMQSSGVDPETEYTNNAMRLTAAVTI
LMAVWWMTEAIPLAATALIPLVAFPAFQVVDFGKAAAPYANPTIFLFLGGFLMALGLQKWNLHRRMALAVVLAVGTKPKQ
LVLGFMVATGFLSMWVSNTATAVVMLPIGMSVLALTAETVGGMKNQKKFATGLMLSIAYSASIGSLGTLIGTPPNALLAA
YMSESHDIHIGFGQWMILGVPIAVVFTIIAWLVLTTVFKPEMKEIPGGRELIKREIAEMGPWTAPQVTVGVIFAAAALAW
VFIPLTLDWTGSQLSINDSLIGIAAGLLMFIVPANFKTGERILDWRTAGELPWDVLLLFGGGLSLSAMFTSTGLSLWIGE
LAKGLDALPIFILIFAIAVLVLFLTEFTSNTATAATFLPIMGGVAVGIGLTAGGEQNVLLLTIPVALSATCAFMLPVATP
PNAIAFGSGYIKIGEMVKGGLWLNIIAVILISISTYFVAIPLFGIML

Sequences:

>Translated_527_residues
MSTPDIKEGSAESPGEVMVVGDRREWRRQATGIIAGLVLAALVYLLFPSNSVETVMQSSGVDPETEYTNNAMRLTAAVTI
LMAVWWMTEAIPLAATALIPLVAFPAFQVVDFGKAAAPYANPTIFLFLGGFLMALGLQKWNLHRRMALAVVLAVGTKPKQ
LVLGFMVATGFLSMWVSNTATAVVMLPIGMSVLALTAETVGGMKNQKKFATGLMLSIAYSASIGSLGTLIGTPPNALLAA
YMSESHDIHIGFGQWMILGVPIAVVFTIIAWLVLTTVFKPEMKEIPGGRELIKREIAEMGPWTAPQVTVGVIFAAAALAW
VFIPLTLDWTGSQLSINDSLIGIAAGLLMFIVPANFKTGERILDWRTAGELPWDVLLLFGGGLSLSAMFTSTGLSLWIGE
LAKGLDALPIFILIFAIAVLVLFLTEFTSNTATAATFLPIMGGVAVGIGLTAGGEQNVLLLTIPVALSATCAFMLPVATP
PNAIAFGSGYIKIGEMVKGGLWLNIIAVILISISTYFVAIPLFGIML
>Mature_526_residues
STPDIKEGSAESPGEVMVVGDRREWRRQATGIIAGLVLAALVYLLFPSNSVETVMQSSGVDPETEYTNNAMRLTAAVTIL
MAVWWMTEAIPLAATALIPLVAFPAFQVVDFGKAAAPYANPTIFLFLGGFLMALGLQKWNLHRRMALAVVLAVGTKPKQL
VLGFMVATGFLSMWVSNTATAVVMLPIGMSVLALTAETVGGMKNQKKFATGLMLSIAYSASIGSLGTLIGTPPNALLAAY
MSESHDIHIGFGQWMILGVPIAVVFTIIAWLVLTTVFKPEMKEIPGGRELIKREIAEMGPWTAPQVTVGVIFAAAALAWV
FIPLTLDWTGSQLSINDSLIGIAAGLLMFIVPANFKTGERILDWRTAGELPWDVLLLFGGGLSLSAMFTSTGLSLWIGEL
AKGLDALPIFILIFAIAVLVLFLTEFTSNTATAATFLPIMGGVAVGIGLTAGGEQNVLLLTIPVALSATCAFMLPVATPP
NAIAFGSGYIKIGEMVKGGLWLNIIAVILISISTYFVAIPLFGIML

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=521, Percent_Identity=35.5086372360845, Blast_Score=271, Evalue=1e-72,
Organism=Homo sapiens, GI31377715, Length=529, Percent_Identity=32.1361058601134, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI58761541, Length=525, Percent_Identity=32, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI301069349, Length=518, Percent_Identity=31.2741312741313, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI4506979, Length=534, Percent_Identity=32.3970037453184, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI301069346, Length=484, Percent_Identity=31.8181818181818, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI219802232, Length=443, Percent_Identity=33.6343115124154, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI225637549, Length=583, Percent_Identity=29.6740994854202, Blast_Score=209, Evalue=7e-54,
Organism=Homo sapiens, GI301069353, Length=474, Percent_Identity=30.379746835443, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI225637552, Length=496, Percent_Identity=30.8467741935484, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI31795546, Length=355, Percent_Identity=28.169014084507, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI19923838, Length=372, Percent_Identity=32.258064516129, Blast_Score=148, Evalue=2e-35,
Organism=Escherichia coli, GI1786829, Length=424, Percent_Identity=26.4150943396226, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71988385, Length=453, Percent_Identity=34.878587196468, Blast_Score=239, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI32565804, Length=441, Percent_Identity=34.9206349206349, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI71989118, Length=494, Percent_Identity=31.9838056680162, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17551790, Length=523, Percent_Identity=26.9598470363289, Blast_Score=202, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI32564681, Length=501, Percent_Identity=26.7465069860279, Blast_Score=183, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6324340, Length=459, Percent_Identity=25.4901960784314, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322263, Length=464, Percent_Identity=24.3534482758621, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319885, Length=454, Percent_Identity=24.8898678414097, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45551633, Length=481, Percent_Identity=29.9376299376299, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281366409, Length=481, Percent_Identity=29.9376299376299, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17737623, Length=481, Percent_Identity=29.9376299376299, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24666468, Length=481, Percent_Identity=29.9376299376299, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281362116, Length=533, Percent_Identity=29.0806754221388, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI281362114, Length=533, Percent_Identity=28.8930581613508, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI281362112, Length=533, Percent_Identity=28.8930581613508, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI78706796, Length=490, Percent_Identity=29.3877551020408, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI78706798, Length=490, Percent_Identity=29.3877551020408, Blast_Score=141, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 55870; Mature: 55739

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPDIKEGSAESPGEVMVVGDRREWRRQATGIIAGLVLAALVYLLFPSNSVETVMQSSG
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
VDPETEYTNNAMRLTAAVTILMAVWWMTEAIPLAATALIPLVAFPAFQVVDFGKAAAPYA
CCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCC
NPTIFLFLGGFLMALGLQKWNLHRRMALAVVLAVGTKPKQLVLGFMVATGFLSMWVSNTA
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
TAVVMLPIGMSVLALTAETVGGMKNQKKFATGLMLSIAYSASIGSLGTLIGTPPNALLAA
CEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHH
YMSESHDIHIGFGQWMILGVPIAVVFTIIAWLVLTTVFKPEMKEIPGGRELIKREIAEMG
HHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCC
PWTAPQVTVGVIFAAAALAWVFIPLTLDWTGSQLSINDSLIGIAAGLLMFIVPANFKTGE
CCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCEEEECCHHHHHHHHHHHHHCCCCCCCCC
RILDWRTAGELPWDVLLLFGGGLSLSAMFTSTGLSLWIGELAKGLDALPIFILIFAIAVL
HHEEECCCCCCCHHHHEEECCCCEEEHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
VLFLTEFTSNTATAATFLPIMGGVAVGIGLTAGGEQNVLLLTIPVALSATCAFMLPVATP
HHHHHHHCCCCHHHHHHHHHHCCHHHHEEEECCCCCCEEEEEECHHHHHHHHHEEECCCC
PNAIAFGSGYIKIGEMVKGGLWLNIIAVILISISTYFVAIPLFGIML
CCCEEECCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STPDIKEGSAESPGEVMVVGDRREWRRQATGIIAGLVLAALVYLLFPSNSVETVMQSSG
CCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
VDPETEYTNNAMRLTAAVTILMAVWWMTEAIPLAATALIPLVAFPAFQVVDFGKAAAPYA
CCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCC
NPTIFLFLGGFLMALGLQKWNLHRRMALAVVLAVGTKPKQLVLGFMVATGFLSMWVSNTA
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
TAVVMLPIGMSVLALTAETVGGMKNQKKFATGLMLSIAYSASIGSLGTLIGTPPNALLAA
CEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHH
YMSESHDIHIGFGQWMILGVPIAVVFTIIAWLVLTTVFKPEMKEIPGGRELIKREIAEMG
HHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCC
PWTAPQVTVGVIFAAAALAWVFIPLTLDWTGSQLSINDSLIGIAAGLLMFIVPANFKTGE
CCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCEEEECCHHHHHHHHHHHHHCCCCCCCCC
RILDWRTAGELPWDVLLLFGGGLSLSAMFTSTGLSLWIGELAKGLDALPIFILIFAIAVL
HHEEECCCCCCCHHHHEEECCCCEEEHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
VLFLTEFTSNTATAATFLPIMGGVAVGIGLTAGGEQNVLLLTIPVALSATCAFMLPVATP
HHHHHHHCCCCHHHHHHHHHHCCHHHHEEEECCCCCCEEEEEECHHHHHHHHHEEECCCC
PNAIAFGSGYIKIGEMVKGGLWLNIIAVILISISTYFVAIPLFGIML
CCCEEECCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA