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The map label for this gene is ntdC [H]

Identifier: 145294294

GI number: 145294294

Start: 269842

End: 271071

Strand: Direct

Name: ntdC [H]

Synonym: cgR_0250

Alternate gene names: 145294294

Gene position: 269842-271071 (Clockwise)

Preceding gene: 145294292

Following gene: 145294295

Centisome position: 8.14

GC content: 58.13

Gene sequence:

>1230_bases
GTGACTCAGCAAGAACTTCGCGTAGCTGTCATTGGTGCAGGCATGGCAGGCAAAGCACACGCAGCGGGCTACCGCACCGC
ATCCAGCATCTACTCCACCACTCTGCCCAACATCCGTTTGGTTTCCATCGCGGATGCCAACGTGCAGCTAGCTGAAGAAA
CCGCAGCACGCTTCGGCTTTGAGCGCTTTGATACCTCTTGGCAGGCGATCGTTGAGGCCGATGACATCGATGTCGTCAGC
GTCGTGGTGGCTAACTTCCTGCACCGCGAAATCGTGGAAGCACTTCTGGCGTCCGGCAAGCATGTGCTGTGCGAGAAGCC
ACTGTCAGACACCATCGAAGATGCAGAAGCCATGATTGAGGCAGCCGGCCGTGCAGCAACAAATGGCACCATCGCCCGCA
TCGGACTGACCTACCGCCGTTCCCCAGGCGTGGCACACATCCGTGATCTCGTGCAGTCCGGCGAGCTTGGCAAGGTTCTA
CACGTCACCGGCCACTACTGGACCGACTACGGATCCAACGCACAGGCACCAATCAGCTGGCGTTACAAGGGGCCAAACGG
CTCCGGCGCACTGGCAGATGTGGGAAGCCACCTCACCTACCTGGCAGAATTCGTTGCAGGATCTGACTTCGCCGACGTCC
GTGGTGGCCAGTTGTCCACCGTGATCACCGAGCGTCCCAAGCCACTCGGCGCGATTGTCGGCCACGAAGGCGGCGCAGTT
TCCGATGAATACGAAGCAGTGGAAAATGATGACATTGCATCATTCTCCGGATCCTTCATCAGTGGCGGAACCGCAACCCT
CCAGGTCGGCCGCATTTCCCAGGGACACCCAAACACCCTAGGTTTTGAAGTGTTCTGCGAAAAGGGCTCCGTGCTCTTTG
ATTTCCGCAACTCAGGCGAATTCAAAATCTTCACCCCAGCAACCTCCGGTGACATCAGCCAAGAAGCCGGCTACCGCACC
ATCACCATCGGACCAAAGCACCCATACTGGCGCGGCGGCCTTGCAATGGATGCACCAGGCGTGGGAATTGGCCAAAACGA
AGGCTTCGTTTTCCAGGCACGTGCATTCCTCGAAGAAATCGCCGGAATTCCTGAAGAGGAAAGCCTGCCACGCTGCGCAA
CTCTGGAAGAAGGACTGCACAACATGCAGCTCATTGACGCCGTAGCTCAGTCCGCAGCAGCCGATGGCGCAACCGTTGCA
GTCCCCGTCCTGGCACCAGTTCAAAACTAA

Upstream 100 bases:

>100_bases
ACAAATATAGCTTGTGTTGGAGCGCTCCAATTGCGTAGTGGATCACAATACCGGATCCACATGGTCTAACAACACATCAT
CTTTTCTCGAGGAGGTCATA

Downstream 100 bases:

>100_bases
CAAGAAAGCCTCACCATGAAACTCGGTCTCTACAACGCGATCTTCCACGATCGCACCCTGCCAGAAGCGCTCGCAGCCAT
CAAAGCTGCAGGTCTCACCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTQQELRVAVIGAGMAGKAHAAGYRTASSIYSTTLPNIRLVSIADANVQLAEETAARFGFERFDTSWQAIVEADDIDVVS
VVVANFLHREIVEALLASGKHVLCEKPLSDTIEDAEAMIEAAGRAATNGTIARIGLTYRRSPGVAHIRDLVQSGELGKVL
HVTGHYWTDYGSNAQAPISWRYKGPNGSGALADVGSHLTYLAEFVAGSDFADVRGGQLSTVITERPKPLGAIVGHEGGAV
SDEYEAVENDDIASFSGSFISGGTATLQVGRISQGHPNTLGFEVFCEKGSVLFDFRNSGEFKIFTPATSGDISQEAGYRT
ITIGPKHPYWRGGLAMDAPGVGIGQNEGFVFQARAFLEEIAGIPEEESLPRCATLEEGLHNMQLIDAVAQSAAADGATVA
VPVLAPVQN

Sequences:

>Translated_409_residues
MTQQELRVAVIGAGMAGKAHAAGYRTASSIYSTTLPNIRLVSIADANVQLAEETAARFGFERFDTSWQAIVEADDIDVVS
VVVANFLHREIVEALLASGKHVLCEKPLSDTIEDAEAMIEAAGRAATNGTIARIGLTYRRSPGVAHIRDLVQSGELGKVL
HVTGHYWTDYGSNAQAPISWRYKGPNGSGALADVGSHLTYLAEFVAGSDFADVRGGQLSTVITERPKPLGAIVGHEGGAV
SDEYEAVENDDIASFSGSFISGGTATLQVGRISQGHPNTLGFEVFCEKGSVLFDFRNSGEFKIFTPATSGDISQEAGYRT
ITIGPKHPYWRGGLAMDAPGVGIGQNEGFVFQARAFLEEIAGIPEEESLPRCATLEEGLHNMQLIDAVAQSAAADGATVA
VPVLAPVQN
>Mature_408_residues
TQQELRVAVIGAGMAGKAHAAGYRTASSIYSTTLPNIRLVSIADANVQLAEETAARFGFERFDTSWQAIVEADDIDVVSV
VVANFLHREIVEALLASGKHVLCEKPLSDTIEDAEAMIEAAGRAATNGTIARIGLTYRRSPGVAHIRDLVQSGELGKVLH
VTGHYWTDYGSNAQAPISWRYKGPNGSGALADVGSHLTYLAEFVAGSDFADVRGGQLSTVITERPKPLGAIVGHEGGAVS
DEYEAVENDDIASFSGSFISGGTATLQVGRISQGHPNTLGFEVFCEKGSVLFDFRNSGEFKIFTPATSGDISQEAGYRTI
TIGPKHPYWRGGLAMDAPGVGIGQNEGFVFQARAFLEEIAGIPEEESLPRCATLEEGLHNMQLIDAVAQSAAADGATVAV
PVLAPVQN

Specific function: Part of the ntdABC operon that biosynthesizes the NTD (3,3'-neotrehalosadiamine) antibiotic [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=208, Percent_Identity=31.25, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082405, Length=208, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581117, Length=136, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 43250; Mature: 43119

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQELRVAVIGAGMAGKAHAAGYRTASSIYSTTLPNIRLVSIADANVQLAEETAARFGF
CCHHHEEEEEEECCCCCCCHHCCCHHHHHHHHHCCCCEEEEEEECCCEEHHHHHHHHHCH
ERFDTSWQAIVEADDIDVVSVVVANFLHREIVEALLASGKHVLCEKPLSDTIEDAEAMIE
HHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHH
AAGRAATNGTIARIGLTYRRSPGVAHIRDLVQSGELGKVLHVTGHYWTDYGSNAQAPISW
HHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCCCEEE
RYKGPNGSGALADVGSHLTYLAEFVAGSDFADVRGGQLSTVITERPKPLGAIVGHEGGAV
EEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCC
SDEYEAVENDDIASFSGSFISGGTATLQVGRISQGHPNTLGFEVFCEKGSVLFDFRNSGE
CCHHHHCCCCCCCCCCCCEECCCEEEEEECCCCCCCCCCCCEEEEECCCCEEEEECCCCC
FKIFTPATSGDISQEAGYRTITIGPKHPYWRGGLAMDAPGVGIGQNEGFVFQARAFLEEI
EEEECCCCCCCCHHHCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEHHHHHHHHH
AGIPEEESLPRCATLEEGLHNMQLIDAVAQSAAADGATVAVPVLAPVQN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCC
>Mature Secondary Structure 
TQQELRVAVIGAGMAGKAHAAGYRTASSIYSTTLPNIRLVSIADANVQLAEETAARFGF
CHHHEEEEEEECCCCCCCHHCCCHHHHHHHHHCCCCEEEEEEECCCEEHHHHHHHHHCH
ERFDTSWQAIVEADDIDVVSVVVANFLHREIVEALLASGKHVLCEKPLSDTIEDAEAMIE
HHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHH
AAGRAATNGTIARIGLTYRRSPGVAHIRDLVQSGELGKVLHVTGHYWTDYGSNAQAPISW
HHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCCCEEE
RYKGPNGSGALADVGSHLTYLAEFVAGSDFADVRGGQLSTVITERPKPLGAIVGHEGGAV
EEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCC
SDEYEAVENDDIASFSGSFISGGTATLQVGRISQGHPNTLGFEVFCEKGSVLFDFRNSGE
CCHHHHCCCCCCCCCCCCEECCCEEEEEECCCCCCCCCCCCEEEEECCCCEEEEECCCCC
FKIFTPATSGDISQEAGYRTITIGPKHPYWRGGLAMDAPGVGIGQNEGFVFQARAFLEEI
EEEECCCCCCCCHHHCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEHHHHHHHHH
AGIPEEESLPRCATLEEGLHNMQLIDAVAQSAAADGATVAVPVLAPVQN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]