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The map label for this gene is iolG

Identifier: 145294287

GI number: 145294287

Start: 263327

End: 264340

Strand: Direct

Name: iolG

Synonym: cgR_0243

Alternate gene names: 145294287

Gene position: 263327-264340 (Clockwise)

Preceding gene: 145294286

Following gene: 145294288

Centisome position: 7.95

GC content: 58.88

Gene sequence:

>1014_bases
ATGAGCAAGAGCCTTCGCGTTGGAGTTGTCGGTGCAGGAGCCATGGGCGCTGACCACATCGATCGCATCAACAACCGCAC
CTCTGGCGCACACATCTCCGCCATTATTGAGCCCGATGCAGCCCGTGCTGCCGCAGCTGCAGAAAACGCGCCGGGTGCAC
AGGCCTTCACCCGCATCGAGGACGCCATCGCAGCCGACGCTGTTGACGCAGTGCTGATCGCCGTACCAGGTCAGTTCCAC
GAGCCAGTACTTGTTCCAGCACTGGAGGCAGGCCTTCCCATCCTATGTGAGAAGCCACTGACCCCGGATTCTGAATCCTC
ACTGCGCATCGTCGAGCTGGAGCAGAAGCTGGACAAGCCGCACATCCAGGTTGGTTTCATGCGCCGCTTCGACCCTGAGT
ACAACAACCTGCGCAAACTGGTGGAATCCGGCGAAGCTGGCGAACTGCTCATGCTCCGCGGCCTGCACCGCAACCCAAGC
GTTGGCGAGAACTACACCCAGTCCATGCTGATCACCGACTCCGTCGTCCACGAATTCGATGTCATCCCATGGCTCGCAGG
CTCCCGAGTTGTCTCCGTTGAAGTGAAGTACCCAAAGACCTCCTCACTGGCGCACTCCGGCCTCAAGGAACCAATCCTGG
TGATCATGGAGCTCGAAAACGGCGTGCTTGTCGACGTAGAGATGAACGTAAACATTCAATTCGGATACCAGGTAGCAACC
GAAGCGGTCTTTGAAAAGGGACTTGCCCGCATCGGCCAGCCATCCGGAATGCAGCGCTGGCGCGACGGTGAATTCCTGAT
CAATGAACACACCGATTTCACCACCCGTTTCGCTACCGCCTACGACCGCCAGATCCAGAGCTGGGTCGACGCAGTCCACG
AAGGCACCCTGGTCGCAGGCCCTAACGCATGGGATGGTTACCTGGTTGCACTGTCATGCGAAGCTGGTGTCAAGGCATTC
GACGGCGGCGTCATCCCAGTTGATGCGGCACCTCGCCCAGATTTCTACGCTTAA

Upstream 100 bases:

>100_bases
CATTCCCAATCGCTGAGCGCACCCGCAAGCACATCTTCGGCTGCACCCACTTCGCACGCGTCAACTAACCACTTAAATCA
TCTCAAGGAGTACAAAAATT

Downstream 100 bases:

>100_bases
GGAGTTTTGAACGTGGTTCGTATTGCTCTTGATCCCACCCCCTTCCACCATGATTACGATCTGTTGGATTTCCCCGACGT
CACCGCACGTTTGGGATATG

Product: hypothetical protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSKSLRVGVVGAGAMGADHIDRINNRTSGAHISAIIEPDAARAAAAAENAPGAQAFTRIEDAIAADAVDAVLIAVPGQFH
EPVLVPALEAGLPILCEKPLTPDSESSLRIVELEQKLDKPHIQVGFMRRFDPEYNNLRKLVESGEAGELLMLRGLHRNPS
VGENYTQSMLITDSVVHEFDVIPWLAGSRVVSVEVKYPKTSSLAHSGLKEPILVIMELENGVLVDVEMNVNIQFGYQVAT
EAVFEKGLARIGQPSGMQRWRDGEFLINEHTDFTTRFATAYDRQIQSWVDAVHEGTLVAGPNAWDGYLVALSCEAGVKAF
DGGVIPVDAAPRPDFYA

Sequences:

>Translated_337_residues
MSKSLRVGVVGAGAMGADHIDRINNRTSGAHISAIIEPDAARAAAAAENAPGAQAFTRIEDAIAADAVDAVLIAVPGQFH
EPVLVPALEAGLPILCEKPLTPDSESSLRIVELEQKLDKPHIQVGFMRRFDPEYNNLRKLVESGEAGELLMLRGLHRNPS
VGENYTQSMLITDSVVHEFDVIPWLAGSRVVSVEVKYPKTSSLAHSGLKEPILVIMELENGVLVDVEMNVNIQFGYQVAT
EAVFEKGLARIGQPSGMQRWRDGEFLINEHTDFTTRFATAYDRQIQSWVDAVHEGTLVAGPNAWDGYLVALSCEAGVKAF
DGGVIPVDAAPRPDFYA
>Mature_336_residues
SKSLRVGVVGAGAMGADHIDRINNRTSGAHISAIIEPDAARAAAAAENAPGAQAFTRIEDAIAADAVDAVLIAVPGQFHE
PVLVPALEAGLPILCEKPLTPDSESSLRIVELEQKLDKPHIQVGFMRRFDPEYNNLRKLVESGEAGELLMLRGLHRNPSV
GENYTQSMLITDSVVHEFDVIPWLAGSRVVSVEVKYPKTSSLAHSGLKEPILVIMELENGVLVDVEMNVNIQFGYQVATE
AVFEKGLARIGQPSGMQRWRDGEFLINEHTDFTTRFATAYDRQIQSWVDAVHEGTLVAGPNAWDGYLVALSCEAGVKAFD
GGVIPVDAAPRPDFYA

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family

Homologues:

Organism=Escherichia coli, GI1787307, Length=189, Percent_Identity=29.6296296296296, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLG_CORGB (A4QAF9)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001137108.1
- ProteinModelPortal:   A4QAF9
- STRING:   A4QAF9
- GeneID:   4992142
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_0243
- eggNOG:   COG0673
- HOGENOM:   HBG612336
- OMA:   KPVMCEK
- ProtClustDB:   CLSK632711
- GO:   GO:0005488
- HAMAP:   MF_01671
- InterPro:   IPR016040
- InterPro:   IPR000683
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF01408 GFO_IDH_MocA

EC number: =1.1.1.18

Molecular weight: Translated: 36492; Mature: 36361

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSLRVGVVGAGAMGADHIDRINNRTSGAHISAIIEPDAARAAAAAENAPGAQAFTRIE
CCCCEEEEEEECCCCCHHHHHHHCCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHH
DAIAADAVDAVLIAVPGQFHEPVLVPALEAGLPILCEKPLTPDSESSLRIVELEQKLDKP
HHHHHHHHCEEEEECCCCCCCCEEEEHHHCCCCEEECCCCCCCCCCCEEEEEEHHHCCCC
HIQVGFMRRFDPEYNNLRKLVESGEAGELLMLRGLHRNPSVGENYTQSMLITDSVVHEFD
CEEEEEHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHEEEEHHHHHHHHH
VIPWLAGSRVVSVEVKYPKTSSLAHSGLKEPILVIMELENGVLVDVEMNVNIQFGYQVAT
CCCEECCCEEEEEEEECCCCHHHHHCCCCCCEEEEEEECCCEEEEEEEEEEEEECHHHHH
EAVFEKGLARIGQPSGMQRWRDGEFLINEHTDFTTRFATAYDRQIQSWVDAVHEGTLVAG
HHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PNAWDGYLVALSCEAGVKAFDGGVIPVDAAPRPDFYA
CCCCCCEEEEEEECCCCEECCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
SKSLRVGVVGAGAMGADHIDRINNRTSGAHISAIIEPDAARAAAAAENAPGAQAFTRIE
CCCEEEEEEECCCCCHHHHHHHCCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHH
DAIAADAVDAVLIAVPGQFHEPVLVPALEAGLPILCEKPLTPDSESSLRIVELEQKLDKP
HHHHHHHHCEEEEECCCCCCCCEEEEHHHCCCCEEECCCCCCCCCCCEEEEEEHHHCCCC
HIQVGFMRRFDPEYNNLRKLVESGEAGELLMLRGLHRNPSVGENYTQSMLITDSVVHEFD
CEEEEEHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHEEEEHHHHHHHHH
VIPWLAGSRVVSVEVKYPKTSSLAHSGLKEPILVIMELENGVLVDVEMNVNIQFGYQVAT
CCCEECCCEEEEEEEECCCCHHHHHCCCCCCEEEEEEECCCEEEEEEEEEEEEECHHHHH
EAVFEKGLARIGQPSGMQRWRDGEFLINEHTDFTTRFATAYDRQIQSWVDAVHEGTLVAG
HHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PNAWDGYLVALSCEAGVKAFDGGVIPVDAAPRPDFYA
CCCCCCEEEEEEECCCCEECCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA