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The map label for this gene is speB [H]

Identifier: 138896978

GI number: 138896978

Start: 3457522

End: 3458397

Strand: Reverse

Name: speB [H]

Synonym: GTNG_3349

Alternate gene names: 138896978

Gene position: 3458397-3457522 (Counterclockwise)

Preceding gene: 138896979

Following gene: 138896977

Centisome position: 97.41

GC content: 54.68

Gene sequence:

>876_bases
ATGCGGTTTGATGAGGCCTATTCTGGCAACGTGTTTATTGGTAGCCACCCGAACTTTGAAGAAAGCGAGGCAGTCATTTA
CGGGATGCCGATGGATTGGACGGTTAGCTACCGGCCCGGTTCGCGATTCGGCCCGGCTCGCATCCGTGAAGTGTCGATCG
GGCTTGAAGAATATAGCCCGTATTTAGATCGGGAGCTCGGTGACATTCGTTATTTTGACGCCGGTGATATTCCGCTGCCG
TTCGGCAACGCTGCTCGCAGCTTGGAGCTGATTGAACAGTTTGTGAAAAAAGTACTGGACGCCGGTAAGTTTCCGCTAGG
CCTTGGCGGCGAACATCTCGTCTCTTGGCCGGTCATTAAAGCGGTGCACGAATATTATCCGGACTTGGCCGTCATTCATA
TGGATGCCCATACCGACTTGCGTGAACATTATGAAGGTGAGCCGTTGTCGCATGCGACGCCGATTCGCAAAGTTGCCGAT
CTCATCGGCCCGACAAACGTCTTTTCATTCGGCATCCGTTCCGGCATGAAAGAAGAGTTCGAATGGGCGAAACAAAACGG
CATGTACATCGCCAAGTTTGACGTACTTGAGCCGCTTCGCTCCGTGCTGCCGAAGCTCGCTGGTCGTCCAGTGTATGTGA
CTATTGACATCGATGTGCTTGACCCGGCTCATGCCCCTGGTACGGGGACGGTCGACGCCGGCGGCATTACGTCGAAAGAG
TTGTTAGCGGCGATCCATGAAATCGCCCGTTCCGATGTCCGCGTCGTTGGTGCCGATCTGGTCGAAGTCGCGCCGGTTTA
CGACCATTCGGAACAGACCGCGAACACAGCGAGCAAGCTTGTTCGCGAAATGTTGCTTGGCTGGGTGGCAAAGTGA

Upstream 100 bases:

>100_bases
GACATCGATACAAAATATTACACAAAAGAACTGCATAAAGCATGCTTCGTATTACCGAAATTTGTCGCGGACTTGGTGAA
ATAAGGGGAGGGGCAAATTG

Downstream 100 bases:

>100_bases
ACATAGGGAAAAGCGCCTAAATCGCGAACGTGCGAGGGCGCTTTTTTTATGTAGTAGGAGAAAGGTTGCGGGAATATATA
CACACCTTATGGAATAATAT

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MRFDEAYSGNVFIGSHPNFEESEAVIYGMPMDWTVSYRPGSRFGPARIREVSIGLEEYSPYLDRELGDIRYFDAGDIPLP
FGNAARSLELIEQFVKKVLDAGKFPLGLGGEHLVSWPVIKAVHEYYPDLAVIHMDAHTDLREHYEGEPLSHATPIRKVAD
LIGPTNVFSFGIRSGMKEEFEWAKQNGMYIAKFDVLEPLRSVLPKLAGRPVYVTIDIDVLDPAHAPGTGTVDAGGITSKE
LLAAIHEIARSDVRVVGADLVEVAPVYDHSEQTANTASKLVREMLLGWVAK

Sequences:

>Translated_291_residues
MRFDEAYSGNVFIGSHPNFEESEAVIYGMPMDWTVSYRPGSRFGPARIREVSIGLEEYSPYLDRELGDIRYFDAGDIPLP
FGNAARSLELIEQFVKKVLDAGKFPLGLGGEHLVSWPVIKAVHEYYPDLAVIHMDAHTDLREHYEGEPLSHATPIRKVAD
LIGPTNVFSFGIRSGMKEEFEWAKQNGMYIAKFDVLEPLRSVLPKLAGRPVYVTIDIDVLDPAHAPGTGTVDAGGITSKE
LLAAIHEIARSDVRVVGADLVEVAPVYDHSEQTANTASKLVREMLLGWVAK
>Mature_291_residues
MRFDEAYSGNVFIGSHPNFEESEAVIYGMPMDWTVSYRPGSRFGPARIREVSIGLEEYSPYLDRELGDIRYFDAGDIPLP
FGNAARSLELIEQFVKKVLDAGKFPLGLGGEHLVSWPVIKAVHEYYPDLAVIHMDAHTDLREHYEGEPLSHATPIRKVAD
LIGPTNVFSFGIRSGMKEEFEWAKQNGMYIAKFDVLEPLRSVLPKLAGRPVYVTIDIDVLDPAHAPGTGTVDAGGITSKE
LLAAIHEIARSDVRVVGADLVEVAPVYDHSEQTANTASKLVREMLLGWVAK

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=278, Percent_Identity=35.6115107913669, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI4502215, Length=288, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI10947139, Length=280, Percent_Identity=27.8571428571429, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789306, Length=301, Percent_Identity=33.8870431893688, Blast_Score=147, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6325146, Length=234, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 32223; Mature: 32223

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDEAYSGNVFIGSHPNFEESEAVIYGMPMDWTVSYRPGSRFGPARIREVSIGLEEYSP
CCCCCCCCCCEEECCCCCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHCCCHHHHCH
YLDRELGDIRYFDAGDIPLPFGNAARSLELIEQFVKKVLDAGKFPLGLGGEHLVSWPVIK
HHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AVHEYYPDLAVIHMDAHTDLREHYEGEPLSHATPIRKVADLIGPTNVFSFGIRSGMKEEF
HHHHHCCCEEEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHH
EWAKQNGMYIAKFDVLEPLRSVLPKLAGRPVYVTIDIDVLDPAHAPGTGTVDAGGITSKE
HHHHHCCCEEEEHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHH
LLAAIHEIARSDVRVVGADLVEVAPVYDHSEQTANTASKLVREMLLGWVAK
HHHHHHHHHHHHHEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFDEAYSGNVFIGSHPNFEESEAVIYGMPMDWTVSYRPGSRFGPARIREVSIGLEEYSP
CCCCCCCCCCEEECCCCCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHCCCHHHHCH
YLDRELGDIRYFDAGDIPLPFGNAARSLELIEQFVKKVLDAGKFPLGLGGEHLVSWPVIK
HHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AVHEYYPDLAVIHMDAHTDLREHYEGEPLSHATPIRKVADLIGPTNVFSFGIRSGMKEEF
HHHHHCCCEEEEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHH
EWAKQNGMYIAKFDVLEPLRSVLPKLAGRPVYVTIDIDVLDPAHAPGTGTVDAGGITSKE
HHHHHCCCEEEEHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHH
LLAAIHEIARSDVRVVGADLVEVAPVYDHSEQTANTASKLVREMLLGWVAK
HHHHHHHHHHHHHEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]