Click here to switch to the map view.

The map label for this gene is argS [H]

Identifier: 138896975

GI number: 138896975

Start: 3454777

End: 3456450

Strand: Reverse

Name: argS [H]

Synonym: GTNG_3346

Alternate gene names: 138896975

Gene position: 3456450-3454777 (Counterclockwise)

Preceding gene: 138896976

Following gene: 138896974

Centisome position: 97.36

GC content: 52.81

Gene sequence:

>1674_bases
ATGAACATTGTCGGACAAATGAAAGAACAGCTGAAAGAGGAAATTCGCCAGGCGGTGGGAAAAGCCGGGCTGGTGGCGGC
TGAGGAGCTGCCAGAAGTATTGCTTGAGGTGCCGCGCGAAAAGGCTCATGGCGATTATTCGACGAATATCGCCATGCAGC
TCGCCCGCATCGCGAAAAAGCCACCGCGGGCAATCGCCGAAGCCATCGTTGAAAAGTTTGACGCCGAGCGTGTTTCGGTG
GCGCGCATCGAGGTAGCCGGCCCAGGGTTTATTAACTTTTACATGGACAATCGCTATTTGACAGCGGTTGTGCCGGCGAT
TTTGCAAGCGGGCCAAGCGTATGGCGAGTCGAATGTCGGCAAAGGGGAAAAAGTGCAAGTCGAGTTCGTCTCGGCTAACC
CGACCGGCAACTTGCACTTAGGTCATGCTCGCGGTGCGGCGGTCGGCGATTCACTTAGCAATATTTTGGCGAAAGCCGGA
TTCGATGTGACGCGTGAATATTACATTAATGATGCCGGCAAACAAATTTATAACTTGGCGAAATCAGTCGAAGCCCGCTA
TTTCCAAGCGCTCGGTACCGATATGCCGCTGCCGGAAGACGGCTATTACGGTGACGACATCGTGGAAATCGGCAAAAAGC
TCGCCGATGAATATGGCGATCGGTTCGTCCATGTGGACGAAGAAGAACGGCTCGCCTTTTTCCGCGAATACGGCCTCCGT
TATGAGCTCGACAAAATTAAAAACGATTTGGCTGCCTTCCGCGTTCCGTTTGACGTTTGGTATTCGGAAACATCGCTTTA
TGAGAGCGGCAAAATCGATGAGGCGCTCTCAACGCTGCGTGAGCGCGGTTACATTTACGAACAGGACGGAGCCACATGGT
TTCGTTCGACGGCGTTTGGCGATGACAAAGACCGTGTGTTAATCAAGCAAGACGGAACGTATACGTATTTGCTTCCGGAC
ATCGCTTACCATCAAGATAAGCTGCGGCGCGGGTTCACGAAGCTAATCAACGTCTGGGGAGCGGATCATCATGGCTACAT
CCCGCGCATGAAAGCAGCGATCGCTGCGCTCGGCTACGATCCAGAAGCGCTCGAGGTCGAGATTATCCAAATGGTGAACT
TATACCAAAACGGCGAGCGCGTCAAAATGAGCAAACGTACTGGCAAAGCGGTGACGATGCGCGAGCTGATGGAAGAAGTC
GGCGTCGATGCTGTCCGCTACTTCTTCGCTATGCGTTCGGGCGATACGCATCTCGATTTTGATATGGACTTGGCTGTTGC
CCAGTCGAATGAAAACCCGGTCTACTATGTCCAATATGCACATGCCCGCGTCTCAAGCATTCTCCGTCAAGCAAAAGAGC
ATCAACTGTCGTATGAAGGCGACGTCGATCTTCATCATCTCGTGGAAACAGAAAAAGAAATCGAGCTGCTCAAAGCGCTT
GGCGACTTCCCGGACGTTGTCGCTGAGGCGGCCTTGAAACGGATGCCACATCGCGTCACCGCCTATGCGTTTGATTTGGC
GTCGGCGCTCCACAGCTTTTACAATGCGGAAAAAGTGCTTGACCTAGACCAGATCGAAAAAACGAAAGCTCGTCTCGCGC
TTGTCAAGGCGGTGCAAATCACGCTGCAAAACGCTCTAGCGTTAATCGGCGTCTCAGCGCCGGAACAAATGTAA

Upstream 100 bases:

>100_bases
CGGAAACAAGGACAGCTCTTTCTCTCGTATGAACTGATGCTAGAGCATGAGCGGAGCGGGCGCCGTACGTTGACGTTAAC
ATTTAAGGGGGTATAAGCCG

Downstream 100 bases:

>100_bases
ACGAATGAGGGAGCGATTGCTCCCTCTTTTGTTTGGGCATGCTAAAGGAAAACAACGGTGGAGGATCAACAAGTGAAAGA
AGTCGTACTCGCACTTATCA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MNIVGQMKEQLKEEIRQAVGKAGLVAAEELPEVLLEVPREKAHGDYSTNIAMQLARIAKKPPRAIAEAIVEKFDAERVSV
ARIEVAGPGFINFYMDNRYLTAVVPAILQAGQAYGESNVGKGEKVQVEFVSANPTGNLHLGHARGAAVGDSLSNILAKAG
FDVTREYYINDAGKQIYNLAKSVEARYFQALGTDMPLPEDGYYGDDIVEIGKKLADEYGDRFVHVDEEERLAFFREYGLR
YELDKIKNDLAAFRVPFDVWYSETSLYESGKIDEALSTLRERGYIYEQDGATWFRSTAFGDDKDRVLIKQDGTYTYLLPD
IAYHQDKLRRGFTKLINVWGADHHGYIPRMKAAIAALGYDPEALEVEIIQMVNLYQNGERVKMSKRTGKAVTMRELMEEV
GVDAVRYFFAMRSGDTHLDFDMDLAVAQSNENPVYYVQYAHARVSSILRQAKEHQLSYEGDVDLHHLVETEKEIELLKAL
GDFPDVVAEAALKRMPHRVTAYAFDLASALHSFYNAEKVLDLDQIEKTKARLALVKAVQITLQNALALIGVSAPEQM

Sequences:

>Translated_557_residues
MNIVGQMKEQLKEEIRQAVGKAGLVAAEELPEVLLEVPREKAHGDYSTNIAMQLARIAKKPPRAIAEAIVEKFDAERVSV
ARIEVAGPGFINFYMDNRYLTAVVPAILQAGQAYGESNVGKGEKVQVEFVSANPTGNLHLGHARGAAVGDSLSNILAKAG
FDVTREYYINDAGKQIYNLAKSVEARYFQALGTDMPLPEDGYYGDDIVEIGKKLADEYGDRFVHVDEEERLAFFREYGLR
YELDKIKNDLAAFRVPFDVWYSETSLYESGKIDEALSTLRERGYIYEQDGATWFRSTAFGDDKDRVLIKQDGTYTYLLPD
IAYHQDKLRRGFTKLINVWGADHHGYIPRMKAAIAALGYDPEALEVEIIQMVNLYQNGERVKMSKRTGKAVTMRELMEEV
GVDAVRYFFAMRSGDTHLDFDMDLAVAQSNENPVYYVQYAHARVSSILRQAKEHQLSYEGDVDLHHLVETEKEIELLKAL
GDFPDVVAEAALKRMPHRVTAYAFDLASALHSFYNAEKVLDLDQIEKTKARLALVKAVQITLQNALALIGVSAPEQM
>Mature_557_residues
MNIVGQMKEQLKEEIRQAVGKAGLVAAEELPEVLLEVPREKAHGDYSTNIAMQLARIAKKPPRAIAEAIVEKFDAERVSV
ARIEVAGPGFINFYMDNRYLTAVVPAILQAGQAYGESNVGKGEKVQVEFVSANPTGNLHLGHARGAAVGDSLSNILAKAG
FDVTREYYINDAGKQIYNLAKSVEARYFQALGTDMPLPEDGYYGDDIVEIGKKLADEYGDRFVHVDEEERLAFFREYGLR
YELDKIKNDLAAFRVPFDVWYSETSLYESGKIDEALSTLRERGYIYEQDGATWFRSTAFGDDKDRVLIKQDGTYTYLLPD
IAYHQDKLRRGFTKLINVWGADHHGYIPRMKAAIAALGYDPEALEVEIIQMVNLYQNGERVKMSKRTGKAVTMRELMEEV
GVDAVRYFFAMRSGDTHLDFDMDLAVAQSNENPVYYVQYAHARVSSILRQAKEHQLSYEGDVDLHHLVETEKEIELLKAL
GDFPDVVAEAALKRMPHRVTAYAFDLASALHSFYNAEKVLDLDQIEKTKARLALVKAVQITLQNALALIGVSAPEQM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=618, Percent_Identity=23.9482200647249, Blast_Score=125, Evalue=8e-29,
Organism=Escherichia coli, GI1788184, Length=609, Percent_Identity=25.944170771757, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71985061, Length=614, Percent_Identity=23.7785016286645, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71985068, Length=575, Percent_Identity=24, Blast_Score=89, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6320548, Length=609, Percent_Identity=26.1083743842365, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321883, Length=562, Percent_Identity=23.8434163701068, Blast_Score=116, Evalue=7e-27,
Organism=Drosophila melanogaster, GI18859963, Length=624, Percent_Identity=22.7564102564103, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62547; Mature: 62547

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVGQMKEQLKEEIRQAVGKAGLVAAEELPEVLLEVPREKAHGDYSTNIAMQLARIAKK
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHCC
PPRAIAEAIVEKFDAERVSVARIEVAGPGFINFYMDNRYLTAVVPAILQAGQAYGESNVG
CHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCC
KGEKVQVEFVSANPTGNLHLGHARGAAVGDSLSNILAKAGFDVTREYYINDAGKQIYNLA
CCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHH
KSVEARYFQALGTDMPLPEDGYYGDDIVEIGKKLADEYGDRFVHVDEEERLAFFREYGLR
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCC
YELDKIKNDLAAFRVPFDVWYSETSLYESGKIDEALSTLRERGYIYEQDGATWFRSTAFG
EEHHHHHHHHHHHCCCHHHHCCHHHHCCCCCHHHHHHHHHHCCCEEECCCCCEEHHCCCC
DDKDRVLIKQDGTYTYLLPDIAYHQDKLRRGFTKLINVWGADHHGYIPRMKAAIAALGYD
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
PEALEVEIIQMVNLYQNGERVKMSKRTGKAVTMRELMEEVGVDAVRYFFAMRSGDTHLDF
CCHHHHHHHHHHHHHCCCCEEEEHHHCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCEECC
DMDLAVAQSNENPVYYVQYAHARVSSILRQAKEHQLSYEGDVDLHHLVETEKEIELLKAL
CCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
GDFPDVVAEAALKRMPHRVTAYAFDLASALHSFYNAEKVLDLDQIEKTKARLALVKAVQI
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TLQNALALIGVSAPEQM
HHHHHHHHEECCCCCCC
>Mature Secondary Structure
MNIVGQMKEQLKEEIRQAVGKAGLVAAEELPEVLLEVPREKAHGDYSTNIAMQLARIAKK
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHCC
PPRAIAEAIVEKFDAERVSVARIEVAGPGFINFYMDNRYLTAVVPAILQAGQAYGESNVG
CHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCC
KGEKVQVEFVSANPTGNLHLGHARGAAVGDSLSNILAKAGFDVTREYYINDAGKQIYNLA
CCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHH
KSVEARYFQALGTDMPLPEDGYYGDDIVEIGKKLADEYGDRFVHVDEEERLAFFREYGLR
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCC
YELDKIKNDLAAFRVPFDVWYSETSLYESGKIDEALSTLRERGYIYEQDGATWFRSTAFG
EEHHHHHHHHHHHCCCHHHHCCHHHHCCCCCHHHHHHHHHHCCCEEECCCCCEEHHCCCC
DDKDRVLIKQDGTYTYLLPDIAYHQDKLRRGFTKLINVWGADHHGYIPRMKAAIAALGYD
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
PEALEVEIIQMVNLYQNGERVKMSKRTGKAVTMRELMEEVGVDAVRYFFAMRSGDTHLDF
CCHHHHHHHHHHHHHCCCCEEEEHHHCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCEECC
DMDLAVAQSNENPVYYVQYAHARVSSILRQAKEHQLSYEGDVDLHHLVETEKEIELLKAL
CCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
GDFPDVVAEAALKRMPHRVTAYAFDLASALHSFYNAEKVLDLDQIEKTKARLALVKAVQI
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TLQNALALIGVSAPEQM
HHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA