Click here to switch to the map view.

The map label for this gene is tdk [H]

Identifier: 138896956

GI number: 138896956

Start: 3430888

End: 3431511

Strand: Reverse

Name: tdk [H]

Synonym: GTNG_3325

Alternate gene names: 138896956

Gene position: 3431511-3430888 (Counterclockwise)

Preceding gene: 138896957

Following gene: 138896955

Centisome position: 96.65

GC content: 56.09

Gene sequence:

>624_bases
ATGTATGTGATGACGCAGTCCGGTTGGCTGGAAGTCATTTGCGGCAGCATGTTTTCCGGCAAATCGGAAGAACTGATCCG
CCGCATCCGCCGCGCCCAGTTTGCCAAACAGGAAGTGAAAGTGTTCAAACCGACGATTGACAACCGCTACAGTGAAGATG
CGGTCGTGTCGCACAACGGGAATTCAGTGATCGCCATCCCGGTCGCAACGCCGGCAGAACTGTTTCGTTATATTTCCGCT
ACCACCGATGTTGTTGCCATTGATGAAGTACAGTTTTTTTCTGATGACATTATTGATGTCGTGCAAACGCTCGCGGATCG
TGGCTATCGCGTCATCGCCGCCGGGTTGGATCAAGACTTCCGCGGCGAACCGTTCGGGCCGGTACCAGCGCTCATGGCCC
TCGCCGAATCGGTGACGAAACTGCAAGCAGTCTGCACCGTTTGCGGCTCCCCGGCTAGCCGGACGCAACGGCTCATTAAC
GGTGCACCCGCCTCTTATGACGATCCGATCATTCTTGTCGGCGCGAGTGAAGCGTACGAACCGCGTTGCCGCCATCACCA
CGAGGTGCCGGGCAAACCAAAAAAGCAGCATGATCATCCGTTTGCTGAACGCGCCAGTGAGTGA

Upstream 100 bases:

>100_bases
ACTGCCGCTCATAGGGGCTATCCTGCTGGCCGCTTCAGTCCCAGTCGGCAGGATTGGCCCGTTTTTCGACGACAGTGTTG
AGCGAAAGGAGAGGCCCCCG

Downstream 100 bases:

>100_bases
AGGGATTCGGTTGGAAATACAGGAAATTAACGCGCTGCACCAGCATGTGCTCGAAGCCTTCATGGCTGGCCAAAAGTGCT
GATAAGTAATGGAAAAAGAT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MYVMTQSGWLEVICGSMFSGKSEELIRRIRRAQFAKQEVKVFKPTIDNRYSEDAVVSHNGNSVIAIPVATPAELFRYISA
TTDVVAIDEVQFFSDDIIDVVQTLADRGYRVIAAGLDQDFRGEPFGPVPALMALAESVTKLQAVCTVCGSPASRTQRLIN
GAPASYDDPIILVGASEAYEPRCRHHHEVPGKPKKQHDHPFAERASE

Sequences:

>Translated_207_residues
MYVMTQSGWLEVICGSMFSGKSEELIRRIRRAQFAKQEVKVFKPTIDNRYSEDAVVSHNGNSVIAIPVATPAELFRYISA
TTDVVAIDEVQFFSDDIIDVVQTLADRGYRVIAAGLDQDFRGEPFGPVPALMALAESVTKLQAVCTVCGSPASRTQRLIN
GAPASYDDPIILVGASEAYEPRCRHHHEVPGKPKKQHDHPFAERASE
>Mature_207_residues
MYVMTQSGWLEVICGSMFSGKSEELIRRIRRAQFAKQEVKVFKPTIDNRYSEDAVVSHNGNSVIAIPVATPAELFRYISA
TTDVVAIDEVQFFSDDIIDVVQTLADRGYRVIAAGLDQDFRGEPFGPVPALMALAESVTKLQAVCTVCGSPASRTQRLIN
GAPASYDDPIILVGASEAYEPRCRHHHEVPGKPKKQHDHPFAERASE

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=191, Percent_Identity=38.2198952879581, Blast_Score=114, Evalue=5e-26,
Organism=Escherichia coli, GI1787490, Length=186, Percent_Identity=26.3440860215054, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17543396, Length=186, Percent_Identity=32.7956989247312, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22819; Mature: 22819

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVMTQSGWLEVICGSMFSGKSEELIRRIRRAQFAKQEVKVFKPTIDNRYSEDAVVSHNG
CEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
NSVIAIPVATPAELFRYISATTDVVAIDEVQFFSDDIIDVVQTLADRGYRVIAAGLDQDF
CEEEEEECCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
RGEPFGPVPALMALAESVTKLQAVCTVCGSPASRTQRLINGAPASYDDPIILVGASEAYE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCC
PRCRHHHEVPGKPKKQHDHPFAERASE
CHHHCCCCCCCCCCCCCCCCHHHHCCC
>Mature Secondary Structure
MYVMTQSGWLEVICGSMFSGKSEELIRRIRRAQFAKQEVKVFKPTIDNRYSEDAVVSHNG
CEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
NSVIAIPVATPAELFRYISATTDVVAIDEVQFFSDDIIDVVQTLADRGYRVIAAGLDQDF
CEEEEEECCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
RGEPFGPVPALMALAESVTKLQAVCTVCGSPASRTQRLINGAPASYDDPIILVGASEAYE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCC
PRCRHHHEVPGKPKKQHDHPFAERASE
CHHHCCCCCCCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA