Click here to switch to the map view.

The map label for this gene is ywlF [H]

Identifier: 138896947

GI number: 138896947

Start: 3422647

End: 3423021

Strand: Reverse

Name: ywlF [H]

Synonym: GTNG_3316

Alternate gene names: 138896947

Gene position: 3423021-3422647 (Counterclockwise)

Preceding gene: 138896948

Following gene: 138896946

Centisome position: 96.41

GC content: 54.93

Gene sequence:

>375_bases
ATGGGCATCGAATATACAGACTTTGGCTGCGACTGTGAAACGTCGGTCGATTACCCGGATTACGCGCTCCCGGTCGCTGA
AAAAGTGGCGCGCGGCGAGTTTGATCGCGGCATTTTAATTTGTGGCACCGGCATTGGCATGACGATCGCAGCGAATAAAG
TAAAAGGGGTGCGCTGCGCCCTTTGTCATGATGTTTACAGCGCGAAACTGACACGCATGCATAACGACAGCAACATCCTC
GCGATGGGCGAGCGCGTGATCGGCCCTGGCTTGGCGCGTGAAATCGCGAAAGCGTGGTTGGAGACGGAATTCGAAGGTGG
CCGCCATGCGCGGCGGATCGGCAAAATTGCCGATTACGAAAACGAACATTTGTAA

Upstream 100 bases:

>100_bases
GAGGCGAGCAGAAAGGAGACGAACGAACTTGAAAGTAGCAATTGCTTCCGACCACGGTGGAATTCGCATTCGTGAAGAAA
TTAAAGCACTTCTTGATGAA

Downstream 100 bases:

>100_bases
AAGACGCATCGTTTCATAAAAATCGCGGCGTATTAATGAGGGGGAGGGCCATGGACGCACTATTGACCGAATGGAGGCAG
CAATGGCAAACCATCTTGCA

Product: ribose 5-phosphate epimerase

Products: D-Ribulose 5-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MGIEYTDFGCDCETSVDYPDYALPVAEKVARGEFDRGILICGTGIGMTIAANKVKGVRCALCHDVYSAKLTRMHNDSNIL
AMGERVIGPGLAREIAKAWLETEFEGGRHARRIGKIADYENEHL

Sequences:

>Translated_124_residues
MGIEYTDFGCDCETSVDYPDYALPVAEKVARGEFDRGILICGTGIGMTIAANKVKGVRCALCHDVYSAKLTRMHNDSNIL
AMGERVIGPGLAREIAKAWLETEFEGGRHARRIGKIADYENEHL
>Mature_123_residues
GIEYTDFGCDCETSVDYPDYALPVAEKVARGEFDRGILICGTGIGMTIAANKVKGVRCALCHDVYSAKLTRMHNDSNILA
MGERVIGPGLAREIAKAWLETEFEGGRHARRIGKIADYENEHL

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=120, Percent_Identity=51.6666666666667, Blast_Score=129, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003500
- InterPro:   IPR004785 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: 5.3.1.6 [C]

Molecular weight: Translated: 13636; Mature: 13505

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIEYTDFGCDCETSVDYPDYALPVAEKVARGEFDRGILICGTGIGMTIAANKVKGVRCA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCHHHH
LCHDVYSAKLTRMHNDSNILAMGERVIGPGLAREIAKAWLETEFEGGRHARRIGKIADYE
HHHHHHHHHHHHCCCCCCEEEECCHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
NEHL
CCCC
>Mature Secondary Structure 
GIEYTDFGCDCETSVDYPDYALPVAEKVARGEFDRGILICGTGIGMTIAANKVKGVRCA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCHHHH
LCHDVYSAKLTRMHNDSNILAMGERVIGPGLAREIAKAWLETEFEGGRHARRIGKIADYE
HHHHHHHHHHHHCCCCCCEEEECCHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
NEHL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 4.4 {D-ribose} 0.83 {D-ribose} [C]

Substrates: alpha-D-Ribose 5-phosphate [C]

Specific reaction: alpha-D-Ribose 5-phosphate <==> D-Ribulose 5-phosphate [C]

General reaction: Intramolecular oxidoreduction; Isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]