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The map label for this gene is yhjB [H]

Identifier: 138896820

GI number: 138896820

Start: 3285161

End: 3286633

Strand: Reverse

Name: yhjB [H]

Synonym: GTNG_3183

Alternate gene names: 138896820

Gene position: 3286633-3285161 (Counterclockwise)

Preceding gene: 138896821

Following gene: 138896817

Centisome position: 92.57

GC content: 48.81

Gene sequence:

>1473_bases
ATGAACGCGGCGTTAATCATTATTTTTGCTTTCTTGTTGTTTTCTCTTTATCTGGGGCTGCAGGCGCGCAGGGGGAAAGA
CATGAACTTGGAGCAATGGACGGTCGGCGGCCGCGGGTTTGGTACGATCTTTGTGTTTCTCTTGATGGCTGGTGAGATTT
ATACGACATTTACATTCCTTGGTGGAAGTGGTTGGGCGTATGGCAAAGGCGGGCCAACGTTTTACATCATCGCTTACGGC
TGCCTAGCTTATGTGTTATCGTATTGGATGCTGCCGAAAGTATGGAAGTACGCGAAAGAGCATCGGTTGATGTCCCAATC
AGATTTCTTCGCTCGCAAGTACGACAGCCCGATGCTCGGTGTTCTCGTAGCGCTGGTAGGGGTTGTGGCGCTCATTCCGT
ATTTAGTGCTGCAACTGAAAGGGCTGGGTATCATCGTTTCCGAAGCTTCCTACGGCACGATTTCCCCGACTGCTGCGATT
TGGATCGGTGTATTGGCGGTCACGATTTACGTAATGATTTCAGGCATTCACGGTTCAGCATGGACGGCAGTTGTGAAAGA
TATCATGATTTTAGTCGTCGCCGTCTTTTTAGGGATCTATCTTCCGTTCCACTATTACGGCGGAATTCAACCGATGTTTG
AGGCCGTTGAGCAGGCGAAACCCGGATTTTTAGCGTTGCCGGACAAAGGGATGAGCGCTTCATGGTTCATTTCAACCGTG
TTGTTGACAGCGCTTGGTTTTTACATGTGGCCTCATACGTTTGGCTCGATTTATTCGGCAAAAAGTGCCAACGTCTTTCG
GAAAAATGCCATTATTTTGCCGATTTATCAGTTAGTGTTGTTATTTGTCTTTTTTGTTGGCTTCACGGCTATTTTGCAAG
TGCCAGGGCTTGAAGGTTCGGATGCAGACTTGGCATTATTAAAATTGTCCATTCAAACGTTTGACCCGTGGGTTGTTGGG
GTCATTGGCGCCGCTGGGCTGCTCACCGCGATGGTGCCAGGGTCGATGATTTTGATGAGCGCATCGACGTTACTTGTGAA
AAATGTGTATCAAGTGTTTGTGCCATCCGCAACGGACGAGCAAGTCGCCAAGTTGGCGAAATATCTCGTCCCGGTCATCG
CTCTTGTTTCATTGTACTTTACGTTCCGGGGCGGTGATACGATCGTGGCGTTGCTTCTTATGGGATACAGCCTTGTGACG
CAATTGTTCCCCGCATTTGTCTTAAGCTTGCAGAAGCAAAATTTTGTCACGAAGCAAGGAGCGTTTGCTGGCATTTTAGC
TGGTGTCGCTACGGTCGCGTACATTACGTTATCCGATAGCAGCGTCGGTACTTTGTTTCCATCACTGCCGCAAGTCGTAC
AAGATTTAAACGTCGGCATTGTCGCGTTGATCGTCAACACTGCGGTGACCATCACAGTCAGCTTGATTCCGTTTCGTTCG
GTTCGTGCTGATGCCGAAAAACGGGTGGTGTAA

Upstream 100 bases:

>100_bases
CGTTTCTGCTATTTTGGCTGGTTGCTTGGGTAATCGTGACTTCGGTCATTATGGCGATTGTTTATCGCTTTGATCCCGCG
GTGAAGGAGGATGAGCAAGC

Downstream 100 bases:

>100_bases
GGAAGAAGGATTGGTTGTCCGTCATTGGTTGGAGAGACACATTCAGGTTATAAGGAAAAAACCGTTCTTTTTTGGTTACG
TTGTCGCAACCGAAAAAGAA

Product: Sodium/proline symporter

Products: Na (I) [Cytoplasm]; pantothenate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MNAALIIIFAFLLFSLYLGLQARRGKDMNLEQWTVGGRGFGTIFVFLLMAGEIYTTFTFLGGSGWAYGKGGPTFYIIAYG
CLAYVLSYWMLPKVWKYAKEHRLMSQSDFFARKYDSPMLGVLVALVGVVALIPYLVLQLKGLGIIVSEASYGTISPTAAI
WIGVLAVTIYVMISGIHGSAWTAVVKDIMILVVAVFLGIYLPFHYYGGIQPMFEAVEQAKPGFLALPDKGMSASWFISTV
LLTALGFYMWPHTFGSIYSAKSANVFRKNAIILPIYQLVLLFVFFVGFTAILQVPGLEGSDADLALLKLSIQTFDPWVVG
VIGAAGLLTAMVPGSMILMSASTLLVKNVYQVFVPSATDEQVAKLAKYLVPVIALVSLYFTFRGGDTIVALLLMGYSLVT
QLFPAFVLSLQKQNFVTKQGAFAGILAGVATVAYITLSDSSVGTLFPSLPQVVQDLNVGIVALIVNTAVTITVSLIPFRS
VRADAEKRVV

Sequences:

>Translated_490_residues
MNAALIIIFAFLLFSLYLGLQARRGKDMNLEQWTVGGRGFGTIFVFLLMAGEIYTTFTFLGGSGWAYGKGGPTFYIIAYG
CLAYVLSYWMLPKVWKYAKEHRLMSQSDFFARKYDSPMLGVLVALVGVVALIPYLVLQLKGLGIIVSEASYGTISPTAAI
WIGVLAVTIYVMISGIHGSAWTAVVKDIMILVVAVFLGIYLPFHYYGGIQPMFEAVEQAKPGFLALPDKGMSASWFISTV
LLTALGFYMWPHTFGSIYSAKSANVFRKNAIILPIYQLVLLFVFFVGFTAILQVPGLEGSDADLALLKLSIQTFDPWVVG
VIGAAGLLTAMVPGSMILMSASTLLVKNVYQVFVPSATDEQVAKLAKYLVPVIALVSLYFTFRGGDTIVALLLMGYSLVT
QLFPAFVLSLQKQNFVTKQGAFAGILAGVATVAYITLSDSSVGTLFPSLPQVVQDLNVGIVALIVNTAVTITVSLIPFRS
VRADAEKRVV
>Mature_490_residues
MNAALIIIFAFLLFSLYLGLQARRGKDMNLEQWTVGGRGFGTIFVFLLMAGEIYTTFTFLGGSGWAYGKGGPTFYIIAYG
CLAYVLSYWMLPKVWKYAKEHRLMSQSDFFARKYDSPMLGVLVALVGVVALIPYLVLQLKGLGIIVSEASYGTISPTAAI
WIGVLAVTIYVMISGIHGSAWTAVVKDIMILVVAVFLGIYLPFHYYGGIQPMFEAVEQAKPGFLALPDKGMSASWFISTV
LLTALGFYMWPHTFGSIYSAKSANVFRKNAIILPIYQLVLLFVFFVGFTAILQVPGLEGSDADLALLKLSIQTFDPWVVG
VIGAAGLLTAMVPGSMILMSASTLLVKNVYQVFVPSATDEQVAKLAKYLVPVIALVSLYFTFRGGDTIVALLLMGYSLVT
QLFPAFVLSLQKQNFVTKQGAFAGILAGVATVAYITLSDSSVGTLFPSLPQVVQDLNVGIVALIVNTAVTITVSLIPFRS
VRADAEKRVV

Specific function: Catalyzes The Sodium-Dependent Uptake Of Extracellular Pantothenate. [C]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Escherichia coli, GI87082237, Length=374, Percent_Identity=22.192513368984, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 53105; Mature: 53105

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAALIIIFAFLLFSLYLGLQARRGKDMNLEQWTVGGRGFGTIFVFLLMAGEIYTTFTFL
CCHHHHHHHHHHHHHHHHCCHHCCCCCCCCCEEECCCCHHHHHHHHHHHHCHHHHHHEEE
GGSGWAYGKGGPTFYIIAYGCLAYVLSYWMLPKVWKYAKEHRLMSQSDFFARKYDSPMLG
CCCCEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
VLVALVGVVALIPYLVLQLKGLGIIVSEASYGTISPTAAIWIGVLAVTIYVMISGIHGSA
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
WTAVVKDIMILVVAVFLGIYLPFHYYGGIQPMFEAVEQAKPGFLALPDKGMSASWFISTV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHH
LLTALGFYMWPHTFGSIYSAKSANVFRKNAIILPIYQLVLLFVFFVGFTAILQVPGLEGS
HHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DADLALLKLSIQTFDPWVVGVIGAAGLLTAMVPGSMILMSASTLLVKNVYQVFVPSATDE
CCCEEEEEEEHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
QVAKLAKYLVPVIALVSLYFTFRGGDTIVALLLMGYSLVTQLFPAFVLSLQKQNFVTKQG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFAGILAGVATVAYITLSDSSVGTLFPSLPQVVQDLNVGIVALIVNTAVTITVSLIPFRS
HHHHHHHHHHHHHEEEECCCCCHHHCHHHHHHHHHCCCHHHHHHHHHHHEEEEEEECCHH
VRADAEKRVV
HHCCHHCCCC
>Mature Secondary Structure
MNAALIIIFAFLLFSLYLGLQARRGKDMNLEQWTVGGRGFGTIFVFLLMAGEIYTTFTFL
CCHHHHHHHHHHHHHHHHCCHHCCCCCCCCCEEECCCCHHHHHHHHHHHHCHHHHHHEEE
GGSGWAYGKGGPTFYIIAYGCLAYVLSYWMLPKVWKYAKEHRLMSQSDFFARKYDSPMLG
CCCCEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
VLVALVGVVALIPYLVLQLKGLGIIVSEASYGTISPTAAIWIGVLAVTIYVMISGIHGSA
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
WTAVVKDIMILVVAVFLGIYLPFHYYGGIQPMFEAVEQAKPGFLALPDKGMSASWFISTV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHH
LLTALGFYMWPHTFGSIYSAKSANVFRKNAIILPIYQLVLLFVFFVGFTAILQVPGLEGS
HHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DADLALLKLSIQTFDPWVVGVIGAAGLLTAMVPGSMILMSASTLLVKNVYQVFVPSATDE
CCCEEEEEEEHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
QVAKLAKYLVPVIALVSLYFTFRGGDTIVALLLMGYSLVTQLFPAFVLSLQKQNFVTKQG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFAGILAGVATVAYITLSDSSVGTLFPSLPQVVQDLNVGIVALIVNTAVTITVSLIPFRS
HHHHHHHHHHHHHEEEECCCCCHHHCHHHHHHHHHCCCHHHHHHHHHHHEEEEEEECCHH
VRADAEKRVV
HHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; pantothenate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + pantothenate [Periplasm] = Na (I) [Cytoplasm] + pantothenate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]