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The map label for this gene is obgE

Identifier: 138896173

GI number: 138896173

Start: 2640910

End: 2642211

Strand: Reverse

Name: obgE

Synonym: GTNG_2536

Alternate gene names: 138896173

Gene position: 2642211-2640910 (Counterclockwise)

Preceding gene: 138896174

Following gene: 138896172

Centisome position: 74.42

GC content: 55.15

Gene sequence:

>1302_bases
ATGTTTGTCGATCAAGTGAAAATTTACGTCAAAGGTGGGGACGGCGGCAACGGTATGGTCGCGTTTCGCCGTGAAAAATA
TGTCCCAAAAGGCGGGCCGGCTGGCGGAGACGGCGGTAAAGGCGGCGACGTTGTGTTCGTCGTCGACGAAGGGCTGCGGA
CGTTAATGGATTTCCGCTACCAACGCCATTTTAAAGCGCCGCGCGGCGAAAACGGCATGTCGAAAAATCAGCACGGCAAA
AATGCTGAAGACTTGCTTGTCAAAGTGCCGCCGGGGACGGTTGTCATCGATGCCGATACAAACGAAGTGCTCGCCGATTT
GACCGAACAAGGACAGCGGTTTGTCGTCGCCAAAGGAGGGCGAGGCGGGCGAGGAAACACCCGGTTTGCGACCGCGGCTA
ATCCGGCGCCAGAGATCGCGGAAAACGGCGAGCCAGGCGAGGAGCGGAACGTCATTTTGGAATTAAAACTGCTCGCTGAT
GTTGGCCTTGTCGGGTTCCCAAGTGTCGGCAAATCGACGTTATTGTCCGTCGTTTCAGCAGCAAGACCGAAAATTGCTGA
GTACCACTTTACGACACTCGTGCCGAATTTGGGCGTCGTCGAAACGGAAGACGGCCGCAGCTTTGTCATGGCTGACTTGC
CGGGGCTCATCGAAGGCGCCCATGAGGGGGTCGGCTTAGGACATCAGTTTTTGCGGCATATTGAACGGACTCGCGTGATC
GTCCATGTCATCGATATGGCCGCGGTGGAAGGGCGCGATCCGTATGACGACTATGTCGTCATCAACGAGGAGTTGAAGCA
ATACAATTTGCGCTTGACTGAACGGCCGCAAATTGTCGCAGCTAATAAAATGGACATGCCAAACGCCGAAGAAAATTTGC
GCCGCTTTAAAGAGAAAGTCGGCGAGGCAGTGCCCGTCTTTCCGATTTCAGCAGCGACAAGGCAAGGGGTGCGCGAGTTG
CTGTTTGCCATTGCTGATTTGCTCGAAACAACGCCGGAGTTTCCGCTCCATGAACTGGAAGAGCCGGCAGTGCAGCGCGT
CGTGTACAAATACGAAAAAGAGGAGCTGCCGTTTACCATTACCCGCGGCAGCGATGGGGCGTTCATTTTGTCGGGTGAAA
AAATTGAGAAACTGTTTAAAATGACCGACTTCTCGCGTGAAGAATCGGTGCGCCGCTTCGCCCGCCAACTGCGTGCCATG
GGAGTCGACGACGCGTTGCGCGAGCGCGGAGCGAAAGACGGCGACACCGTCCGGCTGCTCGATTACGAATTTGAGTTTGT
CGATGACTGGGATGAACGATAA

Upstream 100 bases:

>100_bases
TCTTGAGCACATATTGACAGCATTGAATTGGCTCTGTATACAATAATAAGTATTAGTTACACTAATTTCGCCATGATGGA
AGCGAATCGGAGGAACAGCT

Downstream 100 bases:

>100_bases
AAGCGGAGGAAGGTGCGGTGGAGAAAAAATTTTATTTAGTGCGCGAAGACATCTTGCCGGAAGCGATGAAAAAAGTCGTG
CTGGCGAAACAGCTGCTTGA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFVVDEGLRTLMDFRYQRHFKAPRGENGMSKNQHGK
NAEDLLVKVPPGTVVIDADTNEVLADLTEQGQRFVVAKGGRGGRGNTRFATAANPAPEIAENGEPGEERNVILELKLLAD
VGLVGFPSVGKSTLLSVVSAARPKIAEYHFTTLVPNLGVVETEDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
VHVIDMAAVEGRDPYDDYVVINEELKQYNLRLTERPQIVAANKMDMPNAEENLRRFKEKVGEAVPVFPISAATRQGVREL
LFAIADLLETTPEFPLHELEEPAVQRVVYKYEKEELPFTITRGSDGAFILSGEKIEKLFKMTDFSREESVRRFARQLRAM
GVDDALRERGAKDGDTVRLLDYEFEFVDDWDER

Sequences:

>Translated_433_residues
MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFVVDEGLRTLMDFRYQRHFKAPRGENGMSKNQHGK
NAEDLLVKVPPGTVVIDADTNEVLADLTEQGQRFVVAKGGRGGRGNTRFATAANPAPEIAENGEPGEERNVILELKLLAD
VGLVGFPSVGKSTLLSVVSAARPKIAEYHFTTLVPNLGVVETEDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
VHVIDMAAVEGRDPYDDYVVINEELKQYNLRLTERPQIVAANKMDMPNAEENLRRFKEKVGEAVPVFPISAATRQGVREL
LFAIADLLETTPEFPLHELEEPAVQRVVYKYEKEELPFTITRGSDGAFILSGEKIEKLFKMTDFSREESVRRFARQLRAM
GVDDALRERGAKDGDTVRLLDYEFEFVDDWDER
>Mature_433_residues
MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFVVDEGLRTLMDFRYQRHFKAPRGENGMSKNQHGK
NAEDLLVKVPPGTVVIDADTNEVLADLTEQGQRFVVAKGGRGGRGNTRFATAANPAPEIAENGEPGEERNVILELKLLAD
VGLVGFPSVGKSTLLSVVSAARPKIAEYHFTTLVPNLGVVETEDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
VHVIDMAAVEGRDPYDDYVVINEELKQYNLRLTERPQIVAANKMDMPNAEENLRRFKEKVGEAVPVFPISAATRQGVREL
LFAIADLLETTPEFPLHELEEPAVQRVVYKYEKEELPFTITRGSDGAFILSGEKIEKLFKMTDFSREESVRRFARQLRAM
GVDDALRERGAKDGDTVRLLDYEFEFVDDWDER

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=343, Percent_Identity=40.8163265306122, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI111955139, Length=356, Percent_Identity=35.1123595505618, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI111955063, Length=239, Percent_Identity=34.3096234309623, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=37.7952755905512, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4557537, Length=121, Percent_Identity=38.0165289256198, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI58761500, Length=129, Percent_Identity=34.8837209302326, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789574, Length=359, Percent_Identity=47.9108635097493, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=36.9565217391304, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508313, Length=321, Percent_Identity=40.809968847352, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17552324, Length=309, Percent_Identity=31.0679611650485, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17555344, Length=153, Percent_Identity=32.6797385620915, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=36.4406779661017, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=31.6546762589928, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=162, Percent_Identity=37.6543209876543, Blast_Score=116, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6319281, Length=119, Percent_Identity=41.1764705882353, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321612, Length=126, Percent_Identity=34.9206349206349, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129375, Length=324, Percent_Identity=41.9753086419753, Blast_Score=201, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24585318, Length=309, Percent_Identity=39.1585760517799, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI21356473, Length=150, Percent_Identity=36, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=36.2204724409449, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=36.4341085271318, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=36.4341085271318, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=36.4341085271318, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_GEOTN (A4IRC7)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001126626.1
- ProteinModelPortal:   A4IRC7
- SMR:   A4IRC7
- STRING:   A4IRC7
- GeneID:   4967462
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_2536
- NMPDR:   fig|420246.5.peg.2443
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- PhylomeDB:   A4IRC7
- ProtClustDB:   PRK12297
- BioCyc:   GTHE420246:GTNG_2536-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 48000; Mature: 48000

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFVVDEGLRTLMDFRY
CCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHH
QRHFKAPRGENGMSKNQHGKNAEDLLVKVPPGTVVIDADTNEVLADLTEQGQRFVVAKGG
HHHCCCCCCCCCCCCCCCCCCHHHEEEECCCCEEEEECCCHHHHHHHHHCCCEEEEEECC
RGGRGNTRFATAANPAPEIAENGEPGEERNVILELKLLADVGLVGFPSVGKSTLLSVVSA
CCCCCCCEEEECCCCCCHHHCCCCCCCCCCEEEEEEEEHHCCCCCCCCCCHHHHHHHHHH
ARPKIAEYHFTTLVPNLGVVETEDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
CCCCHHHEEHHHHCCCCCEEECCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHH
VHVIDMAAVEGRDPYDDYVVINEELKQYNLRLTERPQIVAANKMDMPNAEENLRRFKEKV
HHHHHHHHHCCCCCCCCEEEECCHHHHCCCEECCCCCEEEECCCCCCCHHHHHHHHHHHH
GEAVPVFPISAATRQGVRELLFAIADLLETTPEFPLHELEEPAVQRVVYKYEKEELPFTI
CCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHCCCCEEE
TRGSDGAFILSGEKIEKLFKMTDFSREESVRRFARQLRAMGVDDALRERGAKDGDTVRLL
EECCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEE
DYEFEFVDDWDER
EEEEEECCCCCCC
>Mature Secondary Structure
MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFVVDEGLRTLMDFRY
CCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHH
QRHFKAPRGENGMSKNQHGKNAEDLLVKVPPGTVVIDADTNEVLADLTEQGQRFVVAKGG
HHHCCCCCCCCCCCCCCCCCCHHHEEEECCCCEEEEECCCHHHHHHHHHCCCEEEEEECC
RGGRGNTRFATAANPAPEIAENGEPGEERNVILELKLLADVGLVGFPSVGKSTLLSVVSA
CCCCCCCEEEECCCCCCHHHCCCCCCCCCCEEEEEEEEHHCCCCCCCCCCHHHHHHHHHH
ARPKIAEYHFTTLVPNLGVVETEDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
CCCCHHHEEHHHHCCCCCEEECCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHH
VHVIDMAAVEGRDPYDDYVVINEELKQYNLRLTERPQIVAANKMDMPNAEENLRRFKEKV
HHHHHHHHHCCCCCCCCEEEECCHHHHCCCEECCCCCEEEECCCCCCCHHHHHHHHHHHH
GEAVPVFPISAATRQGVRELLFAIADLLETTPEFPLHELEEPAVQRVVYKYEKEELPFTI
CCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHCCCCEEE
TRGSDGAFILSGEKIEKLFKMTDFSREESVRRFARQLRAMGVDDALRERGAKDGDTVRLL
EECCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEE
DYEFEFVDDWDER
EEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA