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The map label for this gene is aroE [H]

Identifier: 138896097

GI number: 138896097

Start: 2566112

End: 2566942

Strand: Reverse

Name: aroE [H]

Synonym: GTNG_2460

Alternate gene names: 138896097

Gene position: 2566942-2566112 (Counterclockwise)

Preceding gene: 138896098

Following gene: 138896096

Centisome position: 72.3

GC content: 54.51

Gene sequence:

>831_bases
ATGGAAAACGTATACGGGCTGCTCGGTTTTCCGGTTGAGCACTCGCTGTCACCGCTCATGCATAATGACGCGTTTGCCTA
TTTCGGCATTTCGGCGCGCTATCACTTGTTTTCCGTCAACCCGGAGCAAGTCGGTGAAGCCATCGCCGGGGTGCGGGCGC
TCGGTATCGCCGGGGTGAATGTGACAATTCCGCATAAAATGGCAGTCATTCCGTTTTTGGACGAAGTGGACGAGCATGCG
CGCCGCATTGGGGCGGTCAACACGATTGTCAATGACAGCGGCCGGCTTATCGGCTATAATACGGACGGACCTGGATACGT
TAAGGCGCTCGAAGAGGAAATGGATATCCATCTTGATGGCAAGCGGATTTTGCTCATCGGTGCCGGCGGAGGGGCGCGCG
GTATTTATTTTTCGCTGCTGTCGACCGCAGCCGAGCGCATTGATATCGCTAACCGAACGGCGGAAAAAGCGGCGCGGCTT
ATCGGTGAAGGGGACGAGCGCCGCTCCACTTTTTTCCCGCTTGCTGAGGCCGAGAGACGGCTGGCTGAATATGATATTAT
TATCAATACGACTTCGGTCGGCATGCATCCGCATGTTGATGAACAACCGCTTTCCCTTCAACAGATGCGGCCGGGAACGG
TTGTATCGGATATTATTTACAATCCATTGGAAACGAAATGGCTGAAGGAAGCGAAAGCGCGCGGCGCCCGCGTGCAAAAC
GGCGTCGGTATGCTCGTGTACCAAGGGGCGCTCGCTTTTGAAAAATGGACTGGCCAATGGCCGGATGTCAATCGGATGAA
ACAGCTTGTCATCAATCAGTTGAGGAGGTAA

Upstream 100 bases:

>100_bases
GTGCAACGATCCGGGCGCCCAACTCGTCGTCCATGCTCCTAAAGGAGTCGATGTGTTTATTCGCCAGTCGTTGATTTAAC
GAGTACGGGAGGGGAGAAAA

Downstream 100 bases:

>100_bases
CATATGTTAACGGGAAAACAAAAACGATTTTTACGGGCGCAAGCCCACCATTTAAAGCCGATTTTTCAAGTTGGCAAAGG
TGGCGTGACGGAGGCGATGA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MENVYGLLGFPVEHSLSPLMHNDAFAYFGISARYHLFSVNPEQVGEAIAGVRALGIAGVNVTIPHKMAVIPFLDEVDEHA
RRIGAVNTIVNDSGRLIGYNTDGPGYVKALEEEMDIHLDGKRILLIGAGGGARGIYFSLLSTAAERIDIANRTAEKAARL
IGEGDERRSTFFPLAEAERRLAEYDIIINTTSVGMHPHVDEQPLSLQQMRPGTVVSDIIYNPLETKWLKEAKARGARVQN
GVGMLVYQGALAFEKWTGQWPDVNRMKQLVINQLRR

Sequences:

>Translated_276_residues
MENVYGLLGFPVEHSLSPLMHNDAFAYFGISARYHLFSVNPEQVGEAIAGVRALGIAGVNVTIPHKMAVIPFLDEVDEHA
RRIGAVNTIVNDSGRLIGYNTDGPGYVKALEEEMDIHLDGKRILLIGAGGGARGIYFSLLSTAAERIDIANRTAEKAARL
IGEGDERRSTFFPLAEAERRLAEYDIIINTTSVGMHPHVDEQPLSLQQMRPGTVVSDIIYNPLETKWLKEAKARGARVQN
GVGMLVYQGALAFEKWTGQWPDVNRMKQLVINQLRR
>Mature_276_residues
MENVYGLLGFPVEHSLSPLMHNDAFAYFGISARYHLFSVNPEQVGEAIAGVRALGIAGVNVTIPHKMAVIPFLDEVDEHA
RRIGAVNTIVNDSGRLIGYNTDGPGYVKALEEEMDIHLDGKRILLIGAGGGARGIYFSLLSTAAERIDIANRTAEKAARL
IGEGDERRSTFFPLAEAERRLAEYDIIINTTSVGMHPHVDEQPLSLQQMRPGTVVSDIIYNPLETKWLKEAKARGARVQN
GVGMLVYQGALAFEKWTGQWPDVNRMKQLVINQLRR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=275, Percent_Identity=36.3636363636364, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789675, Length=277, Percent_Identity=36.4620938628159, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320332, Length=272, Percent_Identity=29.7794117647059, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30491; Mature: 30491

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENVYGLLGFPVEHSLSPLMHNDAFAYFGISARYHLFSVNPEQVGEAIAGVRALGIAGVN
CCCCCEEECCCHHHCCCHHHCCCCEEEEEECEEEEEEECCHHHHHHHHHHHHHHEEECCE
VTIPHKMAVIPFLDEVDEHARRIGAVNTIVNDSGRLIGYNTDGPGYVKALEEEMDIHLDG
EECCCCEEEEHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCCCHHHHHHHHHCCEEECC
KRILLIGAGGGARGIYFSLLSTAAERIDIANRTAEKAARLIGEGDERRSTFFPLAEAERR
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LAEYDIIINTTSVGMHPHVDEQPLSLQQMRPGTVVSDIIYNPLETKWLKEAKARGARVQN
HHHEEEEEEEECCCCCCCCCCCCCCHHHCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCC
GVGMLVYQGALAFEKWTGQWPDVNRMKQLVINQLRR
CCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MENVYGLLGFPVEHSLSPLMHNDAFAYFGISARYHLFSVNPEQVGEAIAGVRALGIAGVN
CCCCCEEECCCHHHCCCHHHCCCCEEEEEECEEEEEEECCHHHHHHHHHHHHHHEEECCE
VTIPHKMAVIPFLDEVDEHARRIGAVNTIVNDSGRLIGYNTDGPGYVKALEEEMDIHLDG
EECCCCEEEEHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCCCHHHHHHHHHCCEEECC
KRILLIGAGGGARGIYFSLLSTAAERIDIANRTAEKAARLIGEGDERRSTFFPLAEAERR
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LAEYDIIINTTSVGMHPHVDEQPLSLQQMRPGTVVSDIIYNPLETKWLKEAKARGARVQN
HHHEEEEEEEECCCCCCCCCCCCCCHHHCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCC
GVGMLVYQGALAFEKWTGQWPDVNRMKQLVINQLRR
CCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA