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The map label for this gene is prmA [H]

Identifier: 138896075

GI number: 138896075

Start: 2545084

End: 2546022

Strand: Reverse

Name: prmA [H]

Synonym: GTNG_2438

Alternate gene names: 138896075

Gene position: 2546022-2545084 (Counterclockwise)

Preceding gene: 138896076

Following gene: 229577456

Centisome position: 71.71

GC content: 49.73

Gene sequence:

>939_bases
ATGAAATGGTCAGAAATCAGCATCCATACAACGCACGAGGCGGTCGAGGCGATTTCAAACATTTTGCATGAGGCGGGCGC
CGGTGGTGTTGTTATCGAAGATCCGTACGATCTTGTCAAAGACCGCGACGACTGGTATGGCGAAATCGTCGAGCTCAATC
CGGACGATTATCCGGAAGAAGGCGTCGTCATTAAGGCGTATTTGCCGGTCAATAGTTTTCTGGGTGAAACGGTAGAACAA
ATCAAGCAGGCAATTAACAATTTATGGTTATACGATATTGATCTTGGCAAAAATAAAATTACGTTGAGCGAAGTGAATGA
GGAAGAATGGGCAACGGCGTGGAAAAAGCATTACCACCCGGTAAAAGTATCGGAAAAGTTTACAATCGTGCCGACATGGG
AAACGTATGAGCCGGCTTCCAACGATGAGCTGATCATCGAAATGGATCCGGGTATGGCGTTTGGCACCGGCACCCACCCG
ACAACGGTCATGTGCCTGCAGGCGCTCGAAAAATATGTGCATCCTGGAGACAATGTCATTGATGTTGGCACCGGCTCCGG
CATTTTAAGCATTGCTGCTGCCATGCTTGGCGCCCATTCGGTGCGGGCGCTCGACTTAGACCCAGTGGCAATCGACAGCG
CGCGGCTGAACGTCAAGCTCAATAAAGTGCAACACGTTGTCACGGTCGCGCAAAACAATTTGCTTGACCATATCGATGAG
CAAGCCGATGTGATCGTCGCCAATATTTTAGCTGAAATCATTTTGCGCTTTACGGCTGACGCCTACCGGCTATTGAAACC
GGGCGGCCGCTTTATCACGTCTGGCATCATTCAGGCGAAGAAGCAAGATGTCAAGGACGGACTGCTTGCTGCTGGATTTT
TCATTGAAGAAGTCAATGTGATGGAAGACTGGGTGGCGTTTGTCGCCATCAAACCGTAA

Upstream 100 bases:

>100_bases
GCGAGTTCGACCGACTCGGTGGGGAAACGATGCACGACGGGTCGCACGGCCGTTTTTTTGAAAAAGTAAAAAAGGCATTT
AAAGGAGAAACGTGAGCGCG

Downstream 100 bases:

>100_bases
GCAAAGAAGGGATGTTTGGTGCAGCGTTATTTCGTTTCCGACCGGGAGCGCCAAGGCGAAAACGTCGTTATCAGCGGCGA
TGACGCCCATCATATTTCCC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKWSEISIHTTHEAVEAISNILHEAGAGGVVIEDPYDLVKDRDDWYGEIVELNPDDYPEEGVVIKAYLPVNSFLGETVEQ
IKQAINNLWLYDIDLGKNKITLSEVNEEEWATAWKKHYHPVKVSEKFTIVPTWETYEPASNDELIIEMDPGMAFGTGTHP
TTVMCLQALEKYVHPGDNVIDVGTGSGILSIAAAMLGAHSVRALDLDPVAIDSARLNVKLNKVQHVVTVAQNNLLDHIDE
QADVIVANILAEIILRFTADAYRLLKPGGRFITSGIIQAKKQDVKDGLLAAGFFIEEVNVMEDWVAFVAIKP

Sequences:

>Translated_312_residues
MKWSEISIHTTHEAVEAISNILHEAGAGGVVIEDPYDLVKDRDDWYGEIVELNPDDYPEEGVVIKAYLPVNSFLGETVEQ
IKQAINNLWLYDIDLGKNKITLSEVNEEEWATAWKKHYHPVKVSEKFTIVPTWETYEPASNDELIIEMDPGMAFGTGTHP
TTVMCLQALEKYVHPGDNVIDVGTGSGILSIAAAMLGAHSVRALDLDPVAIDSARLNVKLNKVQHVVTVAQNNLLDHIDE
QADVIVANILAEIILRFTADAYRLLKPGGRFITSGIIQAKKQDVKDGLLAAGFFIEEVNVMEDWVAFVAIKP
>Mature_312_residues
MKWSEISIHTTHEAVEAISNILHEAGAGGVVIEDPYDLVKDRDDWYGEIVELNPDDYPEEGVVIKAYLPVNSFLGETVEQ
IKQAINNLWLYDIDLGKNKITLSEVNEEEWATAWKKHYHPVKVSEKFTIVPTWETYEPASNDELIIEMDPGMAFGTGTHP
TTVMCLQALEKYVHPGDNVIDVGTGSGILSIAAAMLGAHSVRALDLDPVAIDSARLNVKLNKVQHVVTVAQNNLLDHIDE
QADVIVANILAEIILRFTADAYRLLKPGGRFITSGIIQAKKQDVKDGLLAAGFFIEEVNVMEDWVAFVAIKP

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=253, Percent_Identity=33.201581027668, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34526; Mature: 34526

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWSEISIHTTHEAVEAISNILHEAGAGGVVIEDPYDLVKDRDDWYGEIVELNPDDYPEE
CCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCCCEEEECCCCCCCCC
GVVIKAYLPVNSFLGETVEQIKQAINNLWLYDIDLGKNKITLSEVNEEEWATAWKKHYHP
CEEEEEECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCHHHHHHHHHHCCCC
VKVSEKFTIVPTWETYEPASNDELIIEMDPGMAFGTGTHPTTVMCLQALEKYVHPGDNVI
EEECCEEEEEECCCCCCCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCCCCEE
DVGTGSGILSIAAAMLGAHSVRALDLDPVAIDSARLNVKLNKVQHVVTVAQNNLLDHIDE
EECCCCHHHHHHHHHHCCCCEEEECCCCEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHH
QADVIVANILAEIILRFTADAYRLLKPGGRFITSGIIQAKKQDVKDGLLAAGFFIEEVNV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEDWVAFVAIKP
HHHEEEEEEECC
>Mature Secondary Structure
MKWSEISIHTTHEAVEAISNILHEAGAGGVVIEDPYDLVKDRDDWYGEIVELNPDDYPEE
CCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCCCEEEECCCCCCCCC
GVVIKAYLPVNSFLGETVEQIKQAINNLWLYDIDLGKNKITLSEVNEEEWATAWKKHYHP
CEEEEEECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCHHHHHHHHHHCCCC
VKVSEKFTIVPTWETYEPASNDELIIEMDPGMAFGTGTHPTTVMCLQALEKYVHPGDNVI
EEECCEEEEEECCCCCCCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCCCCEE
DVGTGSGILSIAAAMLGAHSVRALDLDPVAIDSARLNVKLNKVQHVVTVAQNNLLDHIDE
EECCCCHHHHHHHHHHCCCCEEEECCCCEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHH
QADVIVANILAEIILRFTADAYRLLKPGGRFITSGIIQAKKQDVKDGLLAAGFFIEEVNV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEDWVAFVAIKP
HHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA