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The map label for this gene is ispH [H]

Identifier: 138896051

GI number: 138896051

Start: 2522831

End: 2523781

Strand: Direct

Name: ispH [H]

Synonym: GTNG_2414

Alternate gene names: 138896051

Gene position: 2522831-2523781 (Clockwise)

Preceding gene: 138896050

Following gene: 138896071

Centisome position: 71.06

GC content: 49.42

Gene sequence:

>951_bases
ATGGAAGTGATTAAAATTACCCCTCGCGGGTATTGCTACGGAGTTGTCGATGCGATGGTCATCGCCCGCAATGCGGCATT
AGACCCATCATTGCCGCGGCCGATTTACATCCTCGGCATGATCGTCCATAATAAACACGTCACGGACGCGTTTGCCGAAG
AGGGTATCATTACGCTGGATGGAGAAAATCGGCTGGAAATTTTAGAAAAAATTGAGCGAGGTACAGTGATTTTCACCGCC
CACGGCGTGTCTCCAGAAGTGAAAAAACGCGCGCTCGAAAAAGGGCTAGTGACGATCGATGCAACATGCCCGGACGTCAC
GAAAACGCATCGGCTCATCGAGCAAAAGCTCGCTGATGGTTACGATATTATCTACATCGGCAAAAAAGGACATCCGGAAC
CGGAAGGAGCGGTCGGCATCAATCCGGAGCGCATTCATCTCGTCGAAACGCCAGACGATGTTGAGCGGCTTTCTCTTAAA
AACGAACGTCTCATGGTTACAAACCAAACGACGATGAGCCAATGGGATGTAGCCGATATTATGGCGAAAGTGAAAGAAAA
ATACCCGCATGTCGAAATGCATAAAGAAATTTGCCTCGCGACCCAGCTTCGTCAAGAAGCGGTTGCCGAGCAAGCGAAGG
AAGCGGATGTGACGATCGTTGTCGGCGATCCGCGCAGCAACAACTCAAACCGCCTTGCTCAAGTATCGGAAGAAATTGCC
GGCACGAAAGCATACCGTATCGCTGATGTAACGGAAATTGATATCAACTGGATTAAAAACGCGAAAAAGGTGGCTGTCAC
AGCTGGCGCTTCCACTCCGACGCCGATTACGAAAGAAGTAATCGACTTTTTAGAGCAATTCGACCCGAACGATCCGGCAA
CATGGGAGCGGGAACGGAAAGTGCCGCTGCAAAAAATCTTGCCGAAGGTAAAAACAAAGAAAGAAGAATAA

Upstream 100 bases:

>100_bases
CTCCCGCCCTCTTAGGGCGGTTATTCTTTGTCTTATCCTGTTCTCTCAGATATAATGAAAAAGGAAAACCGCCACGGATC
GGCGGCAGGGAGGGAAAACA

Downstream 100 bases:

>100_bases
CAGCCGTTCGTCCATAAACAAAGGCTATCCTGAACAAGCGGTTGAACCGCTTGCAGGACAGCCTTTTTTCATCTCCGCTC
ACACGAACTGAAACGGATCG

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MEVIKITPRGYCYGVVDAMVIARNAALDPSLPRPIYILGMIVHNKHVTDAFAEEGIITLDGENRLEILEKIERGTVIFTA
HGVSPEVKKRALEKGLVTIDATCPDVTKTHRLIEQKLADGYDIIYIGKKGHPEPEGAVGINPERIHLVETPDDVERLSLK
NERLMVTNQTTMSQWDVADIMAKVKEKYPHVEMHKEICLATQLRQEAVAEQAKEADVTIVVGDPRSNNSNRLAQVSEEIA
GTKAYRIADVTEIDINWIKNAKKVAVTAGASTPTPITKEVIDFLEQFDPNDPATWERERKVPLQKILPKVKTKKEE

Sequences:

>Translated_316_residues
MEVIKITPRGYCYGVVDAMVIARNAALDPSLPRPIYILGMIVHNKHVTDAFAEEGIITLDGENRLEILEKIERGTVIFTA
HGVSPEVKKRALEKGLVTIDATCPDVTKTHRLIEQKLADGYDIIYIGKKGHPEPEGAVGINPERIHLVETPDDVERLSLK
NERLMVTNQTTMSQWDVADIMAKVKEKYPHVEMHKEICLATQLRQEAVAEQAKEADVTIVVGDPRSNNSNRLAQVSEEIA
GTKAYRIADVTEIDINWIKNAKKVAVTAGASTPTPITKEVIDFLEQFDPNDPATWERERKVPLQKILPKVKTKKEE
>Mature_316_residues
MEVIKITPRGYCYGVVDAMVIARNAALDPSLPRPIYILGMIVHNKHVTDAFAEEGIITLDGENRLEILEKIERGTVIFTA
HGVSPEVKKRALEKGLVTIDATCPDVTKTHRLIEQKLADGYDIIYIGKKGHPEPEGAVGINPERIHLVETPDDVERLSLK
NERLMVTNQTTMSQWDVADIMAKVKEKYPHVEMHKEICLATQLRQEAVAEQAKEADVTIVVGDPRSNNSNRLAQVSEEIA
GTKAYRIADVTEIDINWIKNAKKVAVTAGASTPTPITKEVIDFLEQFDPNDPATWERERKVPLQKILPKVKTKKEE

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=293, Percent_Identity=39.9317406143345, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 35326; Mature: 35326

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVIKITPRGYCYGVVDAMVIARNAALDPSLPRPIYILGMIVHNKHVTDAFAEEGIITLD
CCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCHHHHHHHCCEEEEC
GENRLEILEKIERGTVIFTAHGVSPEVKKRALEKGLVTIDATCPDVTKTHRLIEQKLADG
CCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCC
YDIIYIGKKGHPEPEGAVGINPERIHLVETPDDVERLSLKNERLMVTNQTTMSQWDVADI
CEEEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEEECCCCCCCCCHHHH
MAKVKEKYPHVEMHKEICLATQLRQEAVAEQAKEADVTIVVGDPRSNNSNRLAQVSEEIA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHH
GTKAYRIADVTEIDINWIKNAKKVAVTAGASTPTPITKEVIDFLEQFDPNDPATWERERK
CCCEEEEECEEEECHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHCC
VPLQKILPKVKTKKEE
CCHHHHHHHHHCCCCC
>Mature Secondary Structure
MEVIKITPRGYCYGVVDAMVIARNAALDPSLPRPIYILGMIVHNKHVTDAFAEEGIITLD
CCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCHHHHHHHCCEEEEC
GENRLEILEKIERGTVIFTAHGVSPEVKKRALEKGLVTIDATCPDVTKTHRLIEQKLADG
CCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCC
YDIIYIGKKGHPEPEGAVGINPERIHLVETPDDVERLSLKNERLMVTNQTTMSQWDVADI
CEEEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEEECCCCCCCCCHHHH
MAKVKEKYPHVEMHKEICLATQLRQEAVAEQAKEADVTIVVGDPRSNNSNRLAQVSEEIA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHH
GTKAYRIADVTEIDINWIKNAKKVAVTAGASTPTPITKEVIDFLEQFDPNDPATWERERK
CCCEEEEECEEEECHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHCC
VPLQKILPKVKTKKEE
CCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA