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The map label for this gene is etfA [H]

Identifier: 138895926

GI number: 138895926

Start: 2402595

End: 2403575

Strand: Direct

Name: etfA [H]

Synonym: GTNG_2285

Alternate gene names: 138895926

Gene position: 2402595-2403575 (Clockwise)

Preceding gene: 138895925

Following gene: 138895927

Centisome position: 67.67

GC content: 42.71

Gene sequence:

>981_bases
ATGACGAGAATCCTTGTACTTGCTGAAATCAAAAATGGAAAGCTCCGCAATGTCTCTTTTGAAGTGTTAACAGTTGCTAG
ACGAATCGCAGGCGATGGAGAGATTGTTGCTTGCTTATTTGGAAGCGATGCAGAAAAATATAGCAACGAACTGGCCAGAT
ATGGCGCACAAAAAGTTTATGTTGTGGAGAATGAGGCCTTAAACCGATACACCCCAGATGGCTATAAACAAGCATTGTTG
CAAGTCATTGACAAAATACAGCCACAAATCTTATTAACAGGACACACCTCCATTGGAAGAGATTTGTTCCCGCGTGTAGC
AGCACGACTAAAGGCTGGATTAGTTTCAGATTGTACGAGTATCGACTTGGACCATGACATCATCTTCACAAGACCGATCT
ATTCCGGAAAAGCGTTTCAGAAAAAACGAATCATAGACGGACTCTTTATGGCCACGATTCGCCCAAACAATATCGAAGCG
GTGGAAAACCCTGTTGTCAGTGAAACGATCAAATTACAAGCAGAAATAAAAGAACTACGAACAGTAGTAAAAGAGATTGT
AAAGAAAACGTCTGGAAAAGTAGATCTTTCAGAAGCAAAAATCATTGTTTCGGGAGGGCGCGGAGTACAAGGACCAGAAG
GATTTCAATTGCTGCAAGAGTTAGCGGATGTACTTGGCGGGGCTGTCGGTGCGTCCCGTGCTGCTTGCGATGCCGGTTAT
TGCGATTATTCTATGCAAATTGGGCAAACCGGCAAAGTAGTCACTCCAGATTTATATATCGCATGCGGCATTTCAGGCGC
GATTCAACATCTAGCGGGAATGTCCAATTCCAAAGTGATCGTGGCGATCAACAAAGACCCCGAAGCAAATATATTCCATG
TCGCAGATTATGGAATTGTCGGGGATTTGTTTGAAGTCGTCCCTCTATTAACTGAGGAGTTTAAGAAATTGCTTTCTAAA
AATAACACTGTAATGAACTAA

Upstream 100 bases:

>100_bases
CGAATTCTTACCGGAGAATTGTCAGATCAGGTGAAAGAATTGGTGCACTTGCTGCGTAATGAAGCGAAGGTCGTTTCACA
TTGAAAAGGGGGAGAGAGAG

Downstream 100 bases:

>100_bases
ATCATGTATTTCATCTTAACCGGGTGATATTTTTCACCCGGTTAAAACGTAATATTCGGACAAAAAGGATGATGGAAAAA
TGATTAAAAACTCTCATCAG

Product: electron transfer flavor protein subunit alpha-like protein

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTRILVLAEIKNGKLRNVSFEVLTVARRIAGDGEIVACLFGSDAEKYSNELARYGAQKVYVVENEALNRYTPDGYKQALL
QVIDKIQPQILLTGHTSIGRDLFPRVAARLKAGLVSDCTSIDLDHDIIFTRPIYSGKAFQKKRIIDGLFMATIRPNNIEA
VENPVVSETIKLQAEIKELRTVVKEIVKKTSGKVDLSEAKIIVSGGRGVQGPEGFQLLQELADVLGGAVGASRAACDAGY
CDYSMQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEANIFHVADYGIVGDLFEVVPLLTEEFKKLLSK
NNTVMN

Sequences:

>Translated_326_residues
MTRILVLAEIKNGKLRNVSFEVLTVARRIAGDGEIVACLFGSDAEKYSNELARYGAQKVYVVENEALNRYTPDGYKQALL
QVIDKIQPQILLTGHTSIGRDLFPRVAARLKAGLVSDCTSIDLDHDIIFTRPIYSGKAFQKKRIIDGLFMATIRPNNIEA
VENPVVSETIKLQAEIKELRTVVKEIVKKTSGKVDLSEAKIIVSGGRGVQGPEGFQLLQELADVLGGAVGASRAACDAGY
CDYSMQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEANIFHVADYGIVGDLFEVVPLLTEEFKKLLSK
NNTVMN
>Mature_325_residues
TRILVLAEIKNGKLRNVSFEVLTVARRIAGDGEIVACLFGSDAEKYSNELARYGAQKVYVVENEALNRYTPDGYKQALLQ
VIDKIQPQILLTGHTSIGRDLFPRVAARLKAGLVSDCTSIDLDHDIIFTRPIYSGKAFQKKRIIDGLFMATIRPNNIEAV
ENPVVSETIKLQAEIKELRTVVKEIVKKTSGKVDLSEAKIIVSGGRGVQGPEGFQLLQELADVLGGAVGASRAACDAGYC
DYSMQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEANIFHVADYGIVGDLFEVVPLLTEEFKKLLSKN
NTVMN

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=317, Percent_Identity=41.0094637223975, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI189181759, Length=265, Percent_Identity=43.0188679245283, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1787990, Length=274, Percent_Identity=35.7664233576642, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786226, Length=235, Percent_Identity=32.3404255319149, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082157, Length=234, Percent_Identity=27.3504273504274, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=320, Percent_Identity=40, Blast_Score=215, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6325261, Length=291, Percent_Identity=40.893470790378, Blast_Score=187, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17136898, Length=311, Percent_Identity=42.7652733118971, Blast_Score=224, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24652801, Length=311, Percent_Identity=42.7652733118971, Blast_Score=224, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 35426; Mature: 35295

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRILVLAEIKNGKLRNVSFEVLTVARRIAGDGEIVACLFGSDAEKYSNELARYGAQKVY
CCEEEEEEEECCCCEECCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCEEE
VVENEALNRYTPDGYKQALLQVIDKIQPQILLTGHTSIGRDLFPRVAARLKAGLVSDCTS
EEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
IDLDHDIIFTRPIYSGKAFQKKRIIDGLFMATIRPNNIEAVENPVVSETIKLQAEIKELR
CCCCCCEEEECCCCCCCHHHHHHHHHHHEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHH
TVVKEIVKKTSGKVDLSEAKIIVSGGRGVQGPEGFQLLQELADVLGGAVGASRAACDAGY
HHHHHHHHHCCCCEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCC
CDYSMQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEANIFHVADYGIV
CCCEEEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHH
GDLFEVVPLLTEEFKKLLSKNNTVMN
HHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TRILVLAEIKNGKLRNVSFEVLTVARRIAGDGEIVACLFGSDAEKYSNELARYGAQKVY
CEEEEEEEECCCCEECCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCEEE
VVENEALNRYTPDGYKQALLQVIDKIQPQILLTGHTSIGRDLFPRVAARLKAGLVSDCTS
EEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
IDLDHDIIFTRPIYSGKAFQKKRIIDGLFMATIRPNNIEAVENPVVSETIKLQAEIKELR
CCCCCCEEEECCCCCCCHHHHHHHHHHHEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHH
TVVKEIVKKTSGKVDLSEAKIIVSGGRGVQGPEGFQLLQELADVLGGAVGASRAACDAGY
HHHHHHHHHCCCCEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCC
CDYSMQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEANIFHVADYGIV
CCCEEEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHH
GDLFEVVPLLTEEFKKLLSKNNTVMN
HHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]