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The map label for this gene is yvrH [H]

Identifier: 138895605

GI number: 138895605

Start: 2082721

End: 2083389

Strand: Direct

Name: yvrH [H]

Synonym: GTNG_1958

Alternate gene names: 138895605

Gene position: 2082721-2083389 (Clockwise)

Preceding gene: 138895602

Following gene: 138895606

Centisome position: 58.66

GC content: 45.59

Gene sequence:

>669_bases
TTGGCACGAGTTTTATACATAGAAGATGAACAGGAAATCGGCCGTTGGGTGACGATGAACCTTACGGAACGTGGGCATCA
TGTGACTTGGCTTCAATCCGGAGAAGAGATCGAAGAACACTTGGCCCATTGCGACCTTGTCATTTTGGATGTGATGCTGC
CGGGGCTGGACGGCTTTTCCATCGGCAAACGGATAAAAAAGGAGCAGCCAGATCTGCCGATTTTGATGCTTTCGGCGCGG
ACTGCCATTGAGGACAAAGTGGAAGGATTGAGTTTCGCCGATGATTATCTGACCAAGCCGTTCCACCCCGATGAGTTGGC
CGCCCGCGTGGAGGTTTTGCTCCGGCGCTTCAACAAAAACGATGAAATCCTGAAACTGAAGCATTTGACCATCCATACAA
AAGATATGCGCATCGTCAATCATGAAACGGGAGAAGAAATTCTACTGACAGGAAAACAATATCAAATTTTCCAATACTTC
CTTCGCCATCTCAATCAAATTTTGACAAAGGAGCAGTTATATGAGGGTGTTTGGGGTGAGCCTTATATTGAAGGAGATAA
AACATTGATGGTGCACATCCGTTATCTTCGTGAAAAACTGGAAAAAGATCCAAAAAATCCAGAAATCATTGAAACGATCC
GGGGAATCGGTTATCGGGTGAGAAAATGA

Upstream 100 bases:

>100_bases
CATTTTCCCGCCAGGAATTGCGCAGTACATGAAGGGATTGACCAAGTCAAACAAGTATTGATTAATATAGAGTGAAGACT
AGAAGAAATGAGGGAGAACG

Downstream 100 bases:

>100_bases
AAAGCGTAAAACGATTGCGGTCGCTGACGGCAAAATATATGGCCATTATTTTAACCGCTCTGTTTCTCATCTATCTTCTT
ATCATCGGAACTAGCCTTTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MARVLYIEDEQEIGRWVTMNLTERGHHVTWLQSGEEIEEHLAHCDLVILDVMLPGLDGFSIGKRIKKEQPDLPILMLSAR
TAIEDKVEGLSFADDYLTKPFHPDELAARVEVLLRRFNKNDEILKLKHLTIHTKDMRIVNHETGEEILLTGKQYQIFQYF
LRHLNQILTKEQLYEGVWGEPYIEGDKTLMVHIRYLREKLEKDPKNPEIIETIRGIGYRVRK

Sequences:

>Translated_222_residues
MARVLYIEDEQEIGRWVTMNLTERGHHVTWLQSGEEIEEHLAHCDLVILDVMLPGLDGFSIGKRIKKEQPDLPILMLSAR
TAIEDKVEGLSFADDYLTKPFHPDELAARVEVLLRRFNKNDEILKLKHLTIHTKDMRIVNHETGEEILLTGKQYQIFQYF
LRHLNQILTKEQLYEGVWGEPYIEGDKTLMVHIRYLREKLEKDPKNPEIIETIRGIGYRVRK
>Mature_221_residues
ARVLYIEDEQEIGRWVTMNLTERGHHVTWLQSGEEIEEHLAHCDLVILDVMLPGLDGFSIGKRIKKEQPDLPILMLSART
AIEDKVEGLSFADDYLTKPFHPDELAARVEVLLRRFNKNDEILKLKHLTIHTKDMRIVNHETGEEILLTGKQYQIFQYFL
RHLNQILTKEQLYEGVWGEPYIEGDKTLMVHIRYLREKLEKDPKNPEIIETIRGIGYRVRK

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=35.5555555555556, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=34.6846846846847, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.5291479820628, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=35.4260089686099, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=36.283185840708, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=29.2576419213974, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=31.6964285714286, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=28.9592760180996, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=33.1818181818182, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=31.8385650224215, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=29.8245614035088, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=29.6943231441048, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=26.4957264957265, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=30.8943089430894, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26111; Mature: 25979

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVLYIEDEQEIGRWVTMNLTERGHHVTWLQSGEEIEEHLAHCDLVILDVMLPGLDGFS
CCEEEEEECHHHCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHH
IGKRIKKEQPDLPILMLSARTAIEDKVEGLSFADDYLTKPFHPDELAARVEVLLRRFNKN
HHHHHHHCCCCCCEEEEECHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCC
DEILKLKHLTIHTKDMRIVNHETGEEILLTGKQYQIFQYFLRHLNQILTKEQLYEGVWGE
CCEEEEEEEEEEECCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PYIEGDKTLMVHIRYLREKLEKDPKNPEIIETIRGIGYRVRK
CEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ARVLYIEDEQEIGRWVTMNLTERGHHVTWLQSGEEIEEHLAHCDLVILDVMLPGLDGFS
CEEEEEECHHHCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHH
IGKRIKKEQPDLPILMLSARTAIEDKVEGLSFADDYLTKPFHPDELAARVEVLLRRFNKN
HHHHHHHCCCCCCEEEEECHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCC
DEILKLKHLTIHTKDMRIVNHETGEEILLTGKQYQIFQYFLRHLNQILTKEQLYEGVWGE
CCEEEEEEEEEEECCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PYIEGDKTLMVHIRYLREKLEKDPKNPEIIETIRGIGYRVRK
CEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]