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The map label for this gene is gbh [H]

Identifier: 138895482

GI number: 138895482

Start: 1949168

End: 1950142

Strand: Direct

Name: gbh [H]

Synonym: GTNG_1830

Alternate gene names: 138895482

Gene position: 1949168-1950142 (Clockwise)

Preceding gene: 138895481

Following gene: 138895483

Centisome position: 54.9

GC content: 49.33

Gene sequence:

>975_bases
ATGTACAAACCAAAAGATTCTTCCCAGTCGCCCCGTTTTTGCGGGGTTCGTACCTTTATGCGATTAGAACAGGTCAAAAC
AACCGACCATGTGGATTTTGTTGTGCTCGGTGTGCCGTTTGATACCGCGGCCTCAAACCGCACTGGTCAACGATACGGCC
CGCAGCATATTCGAAATTTTTCCGTCCTGCTTCGCCCTTACAATCCCGACATGGATATTGATATTTTTGCTTATTGTTCG
GGTGTCGATTACGGGGATGTGGATGTCGTTCCCGGCAATGTGCTGCGCACATACGATCGTATCGTTGAAGAGCTGCGCCC
ATTGTTGAAGAAAGATATCATCCCGATTCTCATGGGCGGTGACCACTCTATTACATTGGGACACTTGCGCGCTTTTTACG
AACGCTTTGGGCCTGTCGCACTCGTTCATTTTGACTCGCATAGCGATACGTGGGATCATTACTATGGAGAAAAATATATG
CACGGTACGCCGTTCCGCCGCGCTGTTGAGGAAGGATTGCTCGATGTAGATCATTCCATTCAAGTCGGTATGCGCGGACC
GCTTTACAGCGCCGATGATATCGAAGACGCACGGCGGCTTGGTTTTGAAGTCATTCCGATGAAAGAAGTCCGCCAAATTG
GTTTTACAGAAGTGATGCGTCGCATTCATCAACGCGTTGGGAACAAACCCGTTTTCGTTTCCTACGATATAGACTTTGTT
GATCCTGCGTTTGCGCCAGGTACCGGCACACCAGAAGTGGGCGGGCCGACGAGCTACGAGGCGCTTGAATACGTAAGAGG
ACTCGATGGGCTAAACATCGTCGGATTTGATCTCGTCGAAGTATTGCCTGCTTACGACAGCGGAGAAATTACAGCAGCAT
TGGCCTCTGCAATTATGTACGAGATGATTACGCTTGTGGCATTAAAGAAAAAGCGGTCACAGGCCAACAATTTGTCAGCA
GCGACAACACCATAA

Upstream 100 bases:

>100_bases
AGAAACGAAGCCGTTTGCGGATGGTTTGTTTTTCCCTTCTTGGCACGTGTTTTGCTTAAACGAATTTGAGAGCATTTTCA
CTTCCTAAGGAGGTTGGGAC

Downstream 100 bases:

>100_bases
AAACCATTTGGTTGAAAAGGAGTGGCCTTCCCTGGCGTACATCAGTGAAGAATAGGACAAAGGAAGAGGATTCGCCGCTT
TTCCTGAAACAAAATATGTT

Product: guanidinobutyrase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MYKPKDSSQSPRFCGVRTFMRLEQVKTTDHVDFVVLGVPFDTAASNRTGQRYGPQHIRNFSVLLRPYNPDMDIDIFAYCS
GVDYGDVDVVPGNVLRTYDRIVEELRPLLKKDIIPILMGGDHSITLGHLRAFYERFGPVALVHFDSHSDTWDHYYGEKYM
HGTPFRRAVEEGLLDVDHSIQVGMRGPLYSADDIEDARRLGFEVIPMKEVRQIGFTEVMRRIHQRVGNKPVFVSYDIDFV
DPAFAPGTGTPEVGGPTSYEALEYVRGLDGLNIVGFDLVEVLPAYDSGEITAALASAIMYEMITLVALKKKRSQANNLSA
ATTP

Sequences:

>Translated_324_residues
MYKPKDSSQSPRFCGVRTFMRLEQVKTTDHVDFVVLGVPFDTAASNRTGQRYGPQHIRNFSVLLRPYNPDMDIDIFAYCS
GVDYGDVDVVPGNVLRTYDRIVEELRPLLKKDIIPILMGGDHSITLGHLRAFYERFGPVALVHFDSHSDTWDHYYGEKYM
HGTPFRRAVEEGLLDVDHSIQVGMRGPLYSADDIEDARRLGFEVIPMKEVRQIGFTEVMRRIHQRVGNKPVFVSYDIDFV
DPAFAPGTGTPEVGGPTSYEALEYVRGLDGLNIVGFDLVEVLPAYDSGEITAALASAIMYEMITLVALKKKRSQANNLSA
ATTP
>Mature_324_residues
MYKPKDSSQSPRFCGVRTFMRLEQVKTTDHVDFVVLGVPFDTAASNRTGQRYGPQHIRNFSVLLRPYNPDMDIDIFAYCS
GVDYGDVDVVPGNVLRTYDRIVEELRPLLKKDIIPILMGGDHSITLGHLRAFYERFGPVALVHFDSHSDTWDHYYGEKYM
HGTPFRRAVEEGLLDVDHSIQVGMRGPLYSADDIEDARRLGFEVIPMKEVRQIGFTEVMRRIHQRVGNKPVFVSYDIDFV
DPAFAPGTGTPEVGGPTSYEALEYVRGLDGLNIVGFDLVEVLPAYDSGEITAALASAIMYEMITLVALKKKRSQANNLSA
ATTP

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=311, Percent_Identity=42.443729903537, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI10947139, Length=315, Percent_Identity=25.3968253968254, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1789306, Length=286, Percent_Identity=42.3076923076923, Blast_Score=197, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6325146, Length=205, Percent_Identity=26.8292682926829, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 36345; Mature: 36345

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKPKDSSQSPRFCGVRTFMRLEQVKTTDHVDFVVLGVPFDTAASNRTGQRYGPQHIRNF
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCE
SVLLRPYNPDMDIDIFAYCSGVDYGDVDVVPGNVLRTYDRIVEELRPLLKKDIIPILMGG
EEEEECCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECC
DHSITLGHLRAFYERFGPVALVHFDSHSDTWDHYYGEKYMHGTPFRRAVEEGLLDVDHSI
CCEEHHHHHHHHHHHHCCEEEEEECCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCCE
QVGMRGPLYSADDIEDARRLGFEVIPMKEVRQIGFTEVMRRIHQRVGNKPVFVSYDIDFV
EECCCCCCCCCCCHHHHHHCCEEEECHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCC
DPAFAPGTGTPEVGGPTSYEALEYVRGLDGLNIVGFDLVEVLPAYDSGEITAALASAIMY
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHH
EMITLVALKKKRSQANNLSAATTP
HHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MYKPKDSSQSPRFCGVRTFMRLEQVKTTDHVDFVVLGVPFDTAASNRTGQRYGPQHIRNF
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCE
SVLLRPYNPDMDIDIFAYCSGVDYGDVDVVPGNVLRTYDRIVEELRPLLKKDIIPILMGG
EEEEECCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECC
DHSITLGHLRAFYERFGPVALVHFDSHSDTWDHYYGEKYMHGTPFRRAVEEGLLDVDHSI
CCEEHHHHHHHHHHHHCCEEEEEECCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCCE
QVGMRGPLYSADDIEDARRLGFEVIPMKEVRQIGFTEVMRRIHQRVGNKPVFVSYDIDFV
EECCCCCCCCCCCHHHHHHCCEEEECHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCC
DPAFAPGTGTPEVGGPTSYEALEYVRGLDGLNIVGFDLVEVLPAYDSGEITAALASAIMY
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHH
EMITLVALKKKRSQANNLSAATTP
HHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA