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The map label for this gene is atoC [C]

Identifier: 138895481

GI number: 138895481

Start: 1947607

End: 1949001

Strand: Direct

Name: atoC [C]

Synonym: GTNG_1829

Alternate gene names: 138895481

Gene position: 1947607-1949001 (Clockwise)

Preceding gene: 138895476

Following gene: 138895482

Centisome position: 54.86

GC content: 42.8

Gene sequence:

>1395_bases
ATGCAACGTGTCACCGACATCTTGGAACTAGAGTTGGATGCGATATTAAAATCATCCACAGACAATATTGTGATTACAGA
CGAAAACGGCATTGTTCTTCGCGCCAGCCCGAATTGCTTATCCATTTACGGAAAAGATGTCTCATATTTAGTGGGAAAGT
CTGTTTATCAATTGGAAAAAGAAAATATCTTTTGTCCTTCCGTTACAGCCAGAGTATTACGAGAGAAAAAAGAGGTCCAA
TTGATGCAGCAAACCACAACCGGGCGGGTTGTCATGGCGACAGGCGTACCCGTGTTTGATCAACAAAACTGCATTGTACG
TGTGATCAGCTTTTCCCATGATTTAACCGAGCTGGAACGCTTGAAAGAAGACTACGAAAAGCTGAGAAAACAGATGGAAC
ATTATCAAACCGAAATCGAGGAATTGAAACCACAAAATATTGTCATCCAAAGCAAAGCGATGGAACGAGTTTGGAAGTTA
GTGCGCCGTGTCGCCCAGTCCGATGCGACTGTTCTTTTCCTCGGTGAGTCTGGAGTCGGAAAAAACGTGTTTGCCCGTTT
CCTTCATCTTAGCAGCTCCCGTCGAAACGAACCATTTATTGAAGTGAACTGCAGCGCGATTCCCGAGTCACTGTTCGAAT
CAGAAATGTTTGGGTACGAAAAAGGCTCGTTTACTGGCGCACAAAAAACCGGAAAACCAGGATTGATCGAATTAGCTGAC
CAAGGAACGCTTTTCCTTGATGAAATTGGTGAACTTCCACTTTCCATGCAAGCCAAACTACTCAAGGTACTGCAAGAGAA
AAAAATGATACGCGTTGGCGGAGTAAAAGAACGAACCGTTGATTTCCGCTTAATCGCCTCCACCAATCGAAACTTAGAGG
AGATGGTAAAACAGGGAATTTTCCGCCAAGATTTGTTTTATCGCTTACATGTGATCCCGATTTATGTCCCTTCCCTGCGC
GAGAGAAAAGAAGATATTTTTATGTTAGCGCAATACTTTTTAGAAAAGTGTAATCAAAAGTACCATATGGATAAATACTT
CCATCCGTCCATTGTGGACCATCTCGTTCATTATCACTGGCCAGGCAATGTGCGGGAGTTGGAAAATATGATCGAACGAT
TGGTCATTACTTCCGAAACAAAAGCCATTTATCCGGAATATCTTCCTTTTTCTATCCAGAAGCATTCAAAGGTTGCGGCA
ACCCCTTCACTAGCAGAAAAAAGAAGTGAACCATCGACACTAAAAGAAGCCGTTGAACAAGTAGAACGGCAATGGCTGCT
GCGTGCAGCCCAACAATGCAAAACAACATACGAGATGGCTGATTATCTTGGCATTAGTCAACCGACGGTCGTACGAAAGT
TAAAAAAGCACCGTATTGATTCAAAAATGAATTAA

Upstream 100 bases:

>100_bases
AAAAAACTTCACGGCAAATCTACAGCCAGAAAAAAGGGTTTTTCACTTTTTTGATAAAGTTAGTAATAGAAAGGTCGATA
GACTTACGAGGAGGGAAACT

Downstream 100 bases:

>100_bases
GATTCATAGCTCCCACCCCGTTGTTTCGTTTCAAAAATCTGTAAGAGGCGGGCTCATCATTATTAAAGAAACGAAGCCGT
TTGCGGATGGTTTGTTTTTC

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF1 [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MQRVTDILELELDAILKSSTDNIVITDENGIVLRASPNCLSIYGKDVSYLVGKSVYQLEKENIFCPSVTARVLREKKEVQ
LMQQTTTGRVVMATGVPVFDQQNCIVRVISFSHDLTELERLKEDYEKLRKQMEHYQTEIEELKPQNIVIQSKAMERVWKL
VRRVAQSDATVLFLGESGVGKNVFARFLHLSSSRRNEPFIEVNCSAIPESLFESEMFGYEKGSFTGAQKTGKPGLIELAD
QGTLFLDEIGELPLSMQAKLLKVLQEKKMIRVGGVKERTVDFRLIASTNRNLEEMVKQGIFRQDLFYRLHVIPIYVPSLR
ERKEDIFMLAQYFLEKCNQKYHMDKYFHPSIVDHLVHYHWPGNVRELENMIERLVITSETKAIYPEYLPFSIQKHSKVAA
TPSLAEKRSEPSTLKEAVEQVERQWLLRAAQQCKTTYEMADYLGISQPTVVRKLKKHRIDSKMN

Sequences:

>Translated_464_residues
MQRVTDILELELDAILKSSTDNIVITDENGIVLRASPNCLSIYGKDVSYLVGKSVYQLEKENIFCPSVTARVLREKKEVQ
LMQQTTTGRVVMATGVPVFDQQNCIVRVISFSHDLTELERLKEDYEKLRKQMEHYQTEIEELKPQNIVIQSKAMERVWKL
VRRVAQSDATVLFLGESGVGKNVFARFLHLSSSRRNEPFIEVNCSAIPESLFESEMFGYEKGSFTGAQKTGKPGLIELAD
QGTLFLDEIGELPLSMQAKLLKVLQEKKMIRVGGVKERTVDFRLIASTNRNLEEMVKQGIFRQDLFYRLHVIPIYVPSLR
ERKEDIFMLAQYFLEKCNQKYHMDKYFHPSIVDHLVHYHWPGNVRELENMIERLVITSETKAIYPEYLPFSIQKHSKVAA
TPSLAEKRSEPSTLKEAVEQVERQWLLRAAQQCKTTYEMADYLGISQPTVVRKLKKHRIDSKMN
>Mature_464_residues
MQRVTDILELELDAILKSSTDNIVITDENGIVLRASPNCLSIYGKDVSYLVGKSVYQLEKENIFCPSVTARVLREKKEVQ
LMQQTTTGRVVMATGVPVFDQQNCIVRVISFSHDLTELERLKEDYEKLRKQMEHYQTEIEELKPQNIVIQSKAMERVWKL
VRRVAQSDATVLFLGESGVGKNVFARFLHLSSSRRNEPFIEVNCSAIPESLFESEMFGYEKGSFTGAQKTGKPGLIELAD
QGTLFLDEIGELPLSMQAKLLKVLQEKKMIRVGGVKERTVDFRLIASTNRNLEEMVKQGIFRQDLFYRLHVIPIYVPSLR
ERKEDIFMLAQYFLEKCNQKYHMDKYFHPSIVDHLVHYHWPGNVRELENMIERLVITSETKAIYPEYLPFSIQKHSKVAA
TPSLAEKRSEPSTLKEAVEQVERQWLLRAAQQCKTTYEMADYLGISQPTVVRKLKKHRIDSKMN

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=356, Percent_Identity=42.6966292134831, Blast_Score=268, Evalue=4e-73,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=41.4330218068536, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI87082117, Length=309, Percent_Identity=44.336569579288, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1790437, Length=313, Percent_Identity=43.7699680511182, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1790299, Length=353, Percent_Identity=38.5269121813031, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789087, Length=348, Percent_Identity=39.9425287356322, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1786524, Length=328, Percent_Identity=40.2439024390244, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI87082152, Length=305, Percent_Identity=41.3114754098361, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1788905, Length=340, Percent_Identity=35.2941176470588, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI87081872, Length=321, Percent_Identity=38.6292834890966, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1787583, Length=319, Percent_Identity=34.4827586206897, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI87081858, Length=460, Percent_Identity=26.5217391304348, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1789828, Length=272, Percent_Identity=33.0882352941176, Blast_Score=135, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR002078 [H]

Pfam domain/function: PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53588; Mature: 53588

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRVTDILELELDAILKSSTDNIVITDENGIVLRASPNCLSIYGKDVSYLVGKSVYQLEK
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCEEEEECCCHHHHHCCHHHHHHH
ENIFCPSVTARVLREKKEVQLMQQTTTGRVVMATGVPVFDQQNCIVRVISFSHDLTELER
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEHHHCCCHHHHHH
LKEDYEKLRKQMEHYQTEIEELKPQNIVIQSKAMERVWKLVRRVAQSDATVLFLGESGVG
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
KNVFARFLHLSSSRRNEPFIEVNCSAIPESLFESEMFGYEKGSFTGAQKTGKPGLIELAD
HHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECC
QGTLFLDEIGELPLSMQAKLLKVLQEKKMIRVGGVKERTVDFRLIASTNRNLEEMVKQGI
CCCEEHHHHCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEEEECCCCCHHHHHHCCH
FRQDLFYRLHVIPIYVPSLRERKEDIFMLAQYFLEKCNQKYHMDKYFHPSIVDHLVHYHW
HHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCC
PGNVRELENMIERLVITSETKAIYPEYLPFSIQKHSKVAATPSLAEKRSEPSTLKEAVEQ
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHH
VERQWLLRAAQQCKTTYEMADYLGISQPTVVRKLKKHRIDSKMN
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQRVTDILELELDAILKSSTDNIVITDENGIVLRASPNCLSIYGKDVSYLVGKSVYQLEK
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCEEEEECCCHHHHHCCHHHHHHH
ENIFCPSVTARVLREKKEVQLMQQTTTGRVVMATGVPVFDQQNCIVRVISFSHDLTELER
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEHHHCCCHHHHHH
LKEDYEKLRKQMEHYQTEIEELKPQNIVIQSKAMERVWKLVRRVAQSDATVLFLGESGVG
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
KNVFARFLHLSSSRRNEPFIEVNCSAIPESLFESEMFGYEKGSFTGAQKTGKPGLIELAD
HHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECC
QGTLFLDEIGELPLSMQAKLLKVLQEKKMIRVGGVKERTVDFRLIASTNRNLEEMVKQGI
CCCEEHHHHCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEEEECCCCCHHHHHHCCH
FRQDLFYRLHVIPIYVPSLRERKEDIFMLAQYFLEKCNQKYHMDKYFHPSIVDHLVHYHW
HHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCC
PGNVRELENMIERLVITSETKAIYPEYLPFSIQKHSKVAATPSLAEKRSEPSTLKEAVEQ
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHH
VERQWLLRAAQQCKTTYEMADYLGISQPTVVRKLKKHRIDSKMN
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]