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The map label for this gene is yesM [H]

Identifier: 138895455

GI number: 138895455

Start: 1910700

End: 1912487

Strand: Reverse

Name: yesM [H]

Synonym: GTNG_1803

Alternate gene names: 138895455

Gene position: 1912487-1910700 (Counterclockwise)

Preceding gene: 138895456

Following gene: 138895454

Centisome position: 53.87

GC content: 43.51

Gene sequence:

>1788_bases
ATGTTGGGAGTACGAAAACGTTGGCGAGTTCGTCATTGGCCGATACGGTACAAGTTTGTTTCCTTGTTGCTGATTTCTAT
GATTGTCCCTGCTCTCGGGCTTGGAGGCCTAGTGAGCTGGGCGGTTGACCGAATCATCGAGCGGCAAGTTAACGAAAATA
CGTTACAGTTAATTAGCCAAGTCAATAGAACATTAGAGTTTTATGTTAATAATATGCAAAATATTACGTATTTAATTGCA
TTTAATCCTGAGACGAAAGCATTTTTTGACCGCTCCACCTCTAGTGATGAGTATGAGATTCGTCAGTTTTTGCAAGGGAT
TACAACGTTATATCCTGAAATTGCTGGAATCTTGGTTGTCAACCAATATGGCGATTATATTAGCAATGAAATGTACAGCC
GCTCCTCGCAACCGTTGACAGAGGAATCGTGGTATCAGGAGGCGGTTAAAAATAAAGGGATTTTTAAAATGATTGGCCAT
CCTGGTGGGCGAAATGTCCTTTCCCATGCCAATTATTCAAGCGAAGAGGTCGTATCCGCAGTACGGGCGATTTTAGAGCC
TGAGACGCAAAAGGTGAAGGGAGTCGTGCTTATTGATTTAAAGCTGCGAGTCATTGCAGAAGCGACAAAAAACGTCCGTC
TTGGGAAATGGGGACATTTGCTAGTGATAGATGAGCGAGGCGAGAGTATTTATACTCCAAGCCCATCGCCGCTTCGAACA
ATTCCGCTGCGATGGGTTCAAGGGAATAGTGGTACGTTTTCGAAAGAAATAAACGGACAACATATCCAGTTGATTTATCA
ACGCTCCCCGTTTACCAATTGGACGATTATCGGAGTATTTTCTGGCAATGAATCGGCGTTAGAAGTGATGGAAGTCCGTT
TTTATATCATCAGCTTCATCTTTTTCGTCTGTTTTATTGCGCTCGGCGCCTCGTATTACTTATCTTTTTCGTTATCGCGC
CCAATCAGCCAGCTAACAGCTTTTATGAAAAAAGCGCAAGCAGGCGATTTAACGGTCCGTTATCATGATGAACGTATGGA
TGAAATTGGGATATTAGGCCGAAGCTTCAACCATATGTTGGATCAAATGCAACGTTTTATTTCTTTGGCAGAATGGCAGG
AGCGACAGCGTTGGGAAGCGGAGTTGCGGGATATGCAGGCCCAAATTAAGCCGCATTTCCTTTACAATACGTTAGATACG
ATTCAGTGGATGGCGCGAAAAAAAGGGGCGGATGATGTAGCGGAAGTGGTGGGTGCGCTGGCAAAGCTGTTCCGCATCGG
GTTGAGCAAAGGAAGGAACATGATTCTTTTCGCTGAGGAGATCGAACATATAAAAAGTTACTTGCACATTCAGAAAGTTC
GTTATAAAGATAAGTTAAACTACACATTTGATATTCCTGAACATTTGCAACAGTTCTATGTGTTAAAATTGTTGTTGCAG
CCAATTGTGGAAAATGCTATTTATCATGGCATTAAACAGCGAAGAGGACCGGGGCATATTTCGATTCAAGCAGAAGAGCG
AGATGGAACGATGTATATTCGCGTGAAAGATGATGGGATTGGAATGTCCCGGGAGCGGCTTGAGGAGCTGCGGAAAAGTC
TAACGATTGACTTTACAGCGGGAGATCAGGAAGGCAAGATGAGAAATATAAAAGGATACGGAATGGTCAATGTACAGGCT
CGGTTGCAATTAACATTCGGTCCGTCTTATCGGTTGTATATTGACAGTGAAGAAGGGAAAGGAACGACCGTGATGATTGT
GCATCCAATGATCATGAACCTCTCCTAG

Upstream 100 bases:

>100_bases
GGATTTGCCTCTGCCGGTGTATGTCGATACAGGGATCACGGTTGTTACGAAAGAAAATGTGGATCGTTTTTATGCCAGAT
AAAGAAGAAATGAGTGATCG

Downstream 100 bases:

>100_bases
GAGGGACGAAGAAATGTGGAAAGTGCTAATTGCGGATGATGAGATGATTATTCGTGAAGGAATTCGAGAATCGATCGACT
GGGCTCAATTCAATATGGAA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MLGVRKRWRVRHWPIRYKFVSLLLISMIVPALGLGGLVSWAVDRIIERQVNENTLQLISQVNRTLEFYVNNMQNITYLIA
FNPETKAFFDRSTSSDEYEIRQFLQGITTLYPEIAGILVVNQYGDYISNEMYSRSSQPLTEESWYQEAVKNKGIFKMIGH
PGGRNVLSHANYSSEEVVSAVRAILEPETQKVKGVVLIDLKLRVIAEATKNVRLGKWGHLLVIDERGESIYTPSPSPLRT
IPLRWVQGNSGTFSKEINGQHIQLIYQRSPFTNWTIIGVFSGNESALEVMEVRFYIISFIFFVCFIALGASYYLSFSLSR
PISQLTAFMKKAQAGDLTVRYHDERMDEIGILGRSFNHMLDQMQRFISLAEWQERQRWEAELRDMQAQIKPHFLYNTLDT
IQWMARKKGADDVAEVVGALAKLFRIGLSKGRNMILFAEEIEHIKSYLHIQKVRYKDKLNYTFDIPEHLQQFYVLKLLLQ
PIVENAIYHGIKQRRGPGHISIQAEERDGTMYIRVKDDGIGMSRERLEELRKSLTIDFTAGDQEGKMRNIKGYGMVNVQA
RLQLTFGPSYRLYIDSEEGKGTTVMIVHPMIMNLS

Sequences:

>Translated_595_residues
MLGVRKRWRVRHWPIRYKFVSLLLISMIVPALGLGGLVSWAVDRIIERQVNENTLQLISQVNRTLEFYVNNMQNITYLIA
FNPETKAFFDRSTSSDEYEIRQFLQGITTLYPEIAGILVVNQYGDYISNEMYSRSSQPLTEESWYQEAVKNKGIFKMIGH
PGGRNVLSHANYSSEEVVSAVRAILEPETQKVKGVVLIDLKLRVIAEATKNVRLGKWGHLLVIDERGESIYTPSPSPLRT
IPLRWVQGNSGTFSKEINGQHIQLIYQRSPFTNWTIIGVFSGNESALEVMEVRFYIISFIFFVCFIALGASYYLSFSLSR
PISQLTAFMKKAQAGDLTVRYHDERMDEIGILGRSFNHMLDQMQRFISLAEWQERQRWEAELRDMQAQIKPHFLYNTLDT
IQWMARKKGADDVAEVVGALAKLFRIGLSKGRNMILFAEEIEHIKSYLHIQKVRYKDKLNYTFDIPEHLQQFYVLKLLLQ
PIVENAIYHGIKQRRGPGHISIQAEERDGTMYIRVKDDGIGMSRERLEELRKSLTIDFTAGDQEGKMRNIKGYGMVNVQA
RLQLTFGPSYRLYIDSEEGKGTTVMIVHPMIMNLS
>Mature_595_residues
MLGVRKRWRVRHWPIRYKFVSLLLISMIVPALGLGGLVSWAVDRIIERQVNENTLQLISQVNRTLEFYVNNMQNITYLIA
FNPETKAFFDRSTSSDEYEIRQFLQGITTLYPEIAGILVVNQYGDYISNEMYSRSSQPLTEESWYQEAVKNKGIFKMIGH
PGGRNVLSHANYSSEEVVSAVRAILEPETQKVKGVVLIDLKLRVIAEATKNVRLGKWGHLLVIDERGESIYTPSPSPLRT
IPLRWVQGNSGTFSKEINGQHIQLIYQRSPFTNWTIIGVFSGNESALEVMEVRFYIISFIFFVCFIALGASYYLSFSLSR
PISQLTAFMKKAQAGDLTVRYHDERMDEIGILGRSFNHMLDQMQRFISLAEWQERQRWEAELRDMQAQIKPHFLYNTLDT
IQWMARKKGADDVAEVVGALAKLFRIGLSKGRNMILFAEEIEHIKSYLHIQKVRYKDKLNYTFDIPEHLQQFYVLKLLLQ
PIVENAIYHGIKQRRGPGHISIQAEERDGTMYIRVKDDGIGMSRERLEELRKSLTIDFTAGDQEGKMRNIKGYGMVNVQA
RLQLTFGPSYRLYIDSEEGKGTTVMIVHPMIMNLS

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=255, Percent_Identity=28.2352941176471, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788723, Length=205, Percent_Identity=31.7073170731707, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68652; Mature: 68652

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGVRKRWRVRHWPIRYKFVSLLLISMIVPALGLGGLVSWAVDRIIERQVNENTLQLISQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHH
VNRTLEFYVNNMQNITYLIAFNPETKAFFDRSTSSDEYEIRQFLQGITTLYPEIAGILVV
HHHHHHHHHCCCCCEEEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEE
NQYGDYISNEMYSRSSQPLTEESWYQEAVKNKGIFKMIGHPGGRNVLSHANYSSEEVVSA
ECCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCHHHHHHH
VRAILEPETQKVKGVVLIDLKLRVIAEATKNVRLGKWGHLLVIDERGESIYTPSPSPLRT
HHHHHCCCCHHCCEEEEEEEHHHHHHHHHCCCEECCCCEEEEEECCCCEEECCCCCCCEE
IPLRWVQGNSGTFSKEINGQHIQLIYQRSPFTNWTIIGVFSGNESALEVMEVRFYIISFI
EEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHH
FFVCFIALGASYYLSFSLSRPISQLTAFMKKAQAGDLTVRYHDERMDEIGILGRSFNHML
HHHHHHHHCHHHEEEEECCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHH
DQMQRFISLAEWQERQRWEAELRDMQAQIKPHFLYNTLDTIQWMARKKGADDVAEVVGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AKLFRIGLSKGRNMILFAEEIEHIKSYLHIQKVRYKDKLNYTFDIPEHLQQFYVLKLLLQ
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHH
PIVENAIYHGIKQRRGPGHISIQAEERDGTMYIRVKDDGIGMSRERLEELRKSLTIDFTA
HHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHEEEEEEC
GDQEGKMRNIKGYGMVNVQARLQLTFGPSYRLYIDSEEGKGTTVMIVHPMIMNLS
CCCCCCEECCCCCEEEEEEEEEEEEECCCEEEEEECCCCCCCEEEEEEEEHHCCC
>Mature Secondary Structure
MLGVRKRWRVRHWPIRYKFVSLLLISMIVPALGLGGLVSWAVDRIIERQVNENTLQLISQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHH
VNRTLEFYVNNMQNITYLIAFNPETKAFFDRSTSSDEYEIRQFLQGITTLYPEIAGILVV
HHHHHHHHHCCCCCEEEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEE
NQYGDYISNEMYSRSSQPLTEESWYQEAVKNKGIFKMIGHPGGRNVLSHANYSSEEVVSA
ECCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCHHHHHHH
VRAILEPETQKVKGVVLIDLKLRVIAEATKNVRLGKWGHLLVIDERGESIYTPSPSPLRT
HHHHHCCCCHHCCEEEEEEEHHHHHHHHHCCCEECCCCEEEEEECCCCEEECCCCCCCEE
IPLRWVQGNSGTFSKEINGQHIQLIYQRSPFTNWTIIGVFSGNESALEVMEVRFYIISFI
EEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHH
FFVCFIALGASYYLSFSLSRPISQLTAFMKKAQAGDLTVRYHDERMDEIGILGRSFNHML
HHHHHHHHCHHHEEEEECCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHH
DQMQRFISLAEWQERQRWEAELRDMQAQIKPHFLYNTLDTIQWMARKKGADDVAEVVGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AKLFRIGLSKGRNMILFAEEIEHIKSYLHIQKVRYKDKLNYTFDIPEHLQQFYVLKLLLQ
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHH
PIVENAIYHGIKQRRGPGHISIQAEERDGTMYIRVKDDGIGMSRERLEELRKSLTIDFTA
HHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHEEEEEEC
GDQEGKMRNIKGYGMVNVQARLQLTFGPSYRLYIDSEEGKGTTVMIVHPMIMNLS
CCCCCCEECCCCCEEEEEEEEEEEEECCCEEEEEECCCCCCCEEEEEEEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]