Click here to switch to the map view.

The map label for this gene is fruA [H]

Identifier: 138895382

GI number: 138895382

Start: 1825200

End: 1827071

Strand: Reverse

Name: fruA [H]

Synonym: GTNG_1726

Alternate gene names: 138895382

Gene position: 1827071-1825200 (Counterclockwise)

Preceding gene: 138895383

Following gene: 138895380

Centisome position: 51.46

GC content: 53.95

Gene sequence:

>1872_bases
ATGAACATCACCGATTTGTTGACAAAAGAAACAATCATTCTTGCACTTCGAGCGCAGACAAAGAGCGAAGTGATTGATGA
ATTGGCCGCCAAGCTCGCTGAGGTGGGAGCAGTCAGCGATGTCGAGGCGTTCAAACAAGTTATCTGGGCGCGTGAAAAGC
AAAGCACGACCGGCGTCGGAGAGGGCATTGCCATTCCGCATGCCAAAACGGCGGCGGTCAAGCGCCCGGCCGTGGCATTC
GGCCGTTCAGCGGAAGGCATTGATTACGAATCGCTCGATGGCAAGCCGAGCCATTTGTTTTTCATGATTGCCGCCCCCGA
AGGTGGGGAGCAAACGCATTTGCAGGCGTTGGCTCGGTTGTCTTCGATGTTGATGGACGCGTCGTTCCGCGCTGCTCTTG
AAAACGCTTCAAATGAAGAGGAAATCGTCCGTTTGTTGGCGGCAAAAGAGAGCGAAGAGGAAGAGCCATCGCTAGGGACA
GCGTCAGCTGACAACGGACGGAAAGTGCTCGCCGTTACCGCCTGCCCGACCGGGATTGCCCATACGTATATGGCTGCTGA
TGCACTGAAAGCAAAAGCAGCGGAAATGGGTGTGATGATAAAAGTAGAAACCAATGGATCTGATGGGGTGAAAAATGCTC
TCACCGCACAGGAGATTGAAGATGCTGCGGCGATTATTGTCGCGGCTGATAAACAAGTCGAAATGGATCGCTTCGATGGC
AAACATGTGATCCAAGTACCGGTCGCCCAAGCGATTCGCCAGCCGGAAACGCTCATTGAGCAAGCGCTGCGCCAAGATGC
GCCAATTTACCGAGCGAGCGGTGCTCCGCAGGGCGGCGCGGGGGCGGCAAAACCGCGCACTGGCTTTTATAAACATTTGA
TGAACGGCGTTTCGAATATGCTTCCATTCGTCGTCGGTGGCGGGATTTTGATCGCGCTCTCCTTCACTTTCGGCATTAAG
GCGTTTGACCCGAACGACCCGTCGTACCATCCATTTGCTAAAGCATTGATGGACATCGGCGGCGGCAATGCATTTGCCTT
AATGATTCCTGTGCTTGCTGCGTTTATCGCGATGAGCATTGCCGATCGGCCAGGATTTGCGCCAGGGATGGTCGGCGGCT
TTATGGCAGCCAACGGCGGCGCTGGTTTTCTCGGCGGATTGATCGCTGGCTTTTTGGCCGGGTATTTGGTCGTCGGGCTG
CGGAAATTATTCAGCCGCTTGCCGCAATCGTTAGAAGGAATTAAACCGGTGTTATTGTATCCGTTGTTCGGCATTTTCTT
GACCGGTATCATTATGATGTATATTGTCATCGATCCAGTGAAAGCGTTGAATGAAGGGTTGAAACATTGGCTTTCCGGCA
TGGGGACGGCGAACTTATTGCTGCTTGGCGCGGTGTTAGGCGGCATGATGGCGGTTGATATGGGCGGCCCGATTAACAAA
GCGGCGTTTACGTTCGGAATCGCCATGATCGATGCTGGCAACTATGCGCCGCATGCGGCCATTATGGCTGGCGGGATGGT
GCCGCCGCTCGGGTTGGCGCTGGCGACGACGTTCTTTAAAAAGAAATTTACGAAAGCCGAACGCGAGGCTGGCAAAACGT
GCTATATTATGGGCGCTTCGTTCATTACGGAAGGAGCGATTCCATTTGCGGCAGCTGATCCGATGCGGGTGATTCCGTCG
ATTATCGTCGGCTCGGCTGTAGCTGGGGCGTTGACGATGTTGTTTGGCATCGGCCTTCCGGCGCCGCACGGCGGCATTTT
CGTCATTCCAATTGTCAAAGGAAGCGCATGGCTGTACATCCTCGCTATTTTGATCGGCTCGGCCGTGACAGCCCTGATGG
TAGGGTTGTGGAAAAAAGAAGTGAAAGAATAA

Upstream 100 bases:

>100_bases
GCGTTTTCCGAAGATTTATGCACGAAAGAAGAAGTGGAAGCACTCGTCGACCGCATTCGCGTCATACGTTTATAAACGGA
AATAAAGGGGGATCGCCAAA

Downstream 100 bases:

>100_bases
GAGAAAAAGCGTTCCGCGGGCAGCGGAGCGCTTTTTTCTTTGCCTCAGTTGCGGACGTTCATTGCTCGTTTCCGTCGGAT
TCAGCATGCCCATATTCACG

Product: PTS system fructose-specific transporter subunit IIBC

Products: NA

Alternate protein names: EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MNITDLLTKETIILALRAQTKSEVIDELAAKLAEVGAVSDVEAFKQVIWAREKQSTTGVGEGIAIPHAKTAAVKRPAVAF
GRSAEGIDYESLDGKPSHLFFMIAAPEGGEQTHLQALARLSSMLMDASFRAALENASNEEEIVRLLAAKESEEEEPSLGT
ASADNGRKVLAVTACPTGIAHTYMAADALKAKAAEMGVMIKVETNGSDGVKNALTAQEIEDAAAIIVAADKQVEMDRFDG
KHVIQVPVAQAIRQPETLIEQALRQDAPIYRASGAPQGGAGAAKPRTGFYKHLMNGVSNMLPFVVGGGILIALSFTFGIK
AFDPNDPSYHPFAKALMDIGGGNAFALMIPVLAAFIAMSIADRPGFAPGMVGGFMAANGGAGFLGGLIAGFLAGYLVVGL
RKLFSRLPQSLEGIKPVLLYPLFGIFLTGIIMMYIVIDPVKALNEGLKHWLSGMGTANLLLLGAVLGGMMAVDMGGPINK
AAFTFGIAMIDAGNYAPHAAIMAGGMVPPLGLALATTFFKKKFTKAEREAGKTCYIMGASFITEGAIPFAAADPMRVIPS
IIVGSAVAGALTMLFGIGLPAPHGGIFVIPIVKGSAWLYILAILIGSAVTALMVGLWKKEVKE

Sequences:

>Translated_623_residues
MNITDLLTKETIILALRAQTKSEVIDELAAKLAEVGAVSDVEAFKQVIWAREKQSTTGVGEGIAIPHAKTAAVKRPAVAF
GRSAEGIDYESLDGKPSHLFFMIAAPEGGEQTHLQALARLSSMLMDASFRAALENASNEEEIVRLLAAKESEEEEPSLGT
ASADNGRKVLAVTACPTGIAHTYMAADALKAKAAEMGVMIKVETNGSDGVKNALTAQEIEDAAAIIVAADKQVEMDRFDG
KHVIQVPVAQAIRQPETLIEQALRQDAPIYRASGAPQGGAGAAKPRTGFYKHLMNGVSNMLPFVVGGGILIALSFTFGIK
AFDPNDPSYHPFAKALMDIGGGNAFALMIPVLAAFIAMSIADRPGFAPGMVGGFMAANGGAGFLGGLIAGFLAGYLVVGL
RKLFSRLPQSLEGIKPVLLYPLFGIFLTGIIMMYIVIDPVKALNEGLKHWLSGMGTANLLLLGAVLGGMMAVDMGGPINK
AAFTFGIAMIDAGNYAPHAAIMAGGMVPPLGLALATTFFKKKFTKAEREAGKTCYIMGASFITEGAIPFAAADPMRVIPS
IIVGSAVAGALTMLFGIGLPAPHGGIFVIPIVKGSAWLYILAILIGSAVTALMVGLWKKEVKE
>Mature_623_residues
MNITDLLTKETIILALRAQTKSEVIDELAAKLAEVGAVSDVEAFKQVIWAREKQSTTGVGEGIAIPHAKTAAVKRPAVAF
GRSAEGIDYESLDGKPSHLFFMIAAPEGGEQTHLQALARLSSMLMDASFRAALENASNEEEIVRLLAAKESEEEEPSLGT
ASADNGRKVLAVTACPTGIAHTYMAADALKAKAAEMGVMIKVETNGSDGVKNALTAQEIEDAAAIIVAADKQVEMDRFDG
KHVIQVPVAQAIRQPETLIEQALRQDAPIYRASGAPQGGAGAAKPRTGFYKHLMNGVSNMLPFVVGGGILIALSFTFGIK
AFDPNDPSYHPFAKALMDIGGGNAFALMIPVLAAFIAMSIADRPGFAPGMVGGFMAANGGAGFLGGLIAGFLAGYLVVGL
RKLFSRLPQSLEGIKPVLLYPLFGIFLTGIIMMYIVIDPVKALNEGLKHWLSGMGTANLLLLGAVLGGMMAVDMGGPINK
AAFTFGIAMIDAGNYAPHAAIMAGGMVPPLGLALATTFFKKKFTKAEREAGKTCYIMGASFITEGAIPFAAADPMRVIPS
IIVGSAVAGALTMLFGIGLPAPHGGIFVIPIVKGSAWLYILAILIGSAVTALMVGLWKKEVKE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788492, Length=458, Percent_Identity=49.7816593886463, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1786951, Length=638, Percent_Identity=35.8934169278997, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI87082348, Length=479, Percent_Identity=34.446764091858, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1790386, Length=304, Percent_Identity=43.75, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1788729, Length=393, Percent_Identity=29.5165394402036, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI2367327, Length=139, Percent_Identity=29.4964028776978, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790387, Length=104, Percent_Identity=42.3076923076923, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788730, Length=90, Percent_Identity=43.3333333333333, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789597, Length=159, Percent_Identity=30.188679245283, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788726, Length=149, Percent_Identity=27.5167785234899, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 65141; Mature: 65141

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2 ; PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITDLLTKETIILALRAQTKSEVIDELAAKLAEVGAVSDVEAFKQVIWAREKQSTTGVG
CCHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCC
EGIAIPHAKTAAVKRPAVAFGRSAEGIDYESLDGKPSHLFFMIAAPEGGEQTHLQALARL
CCCCCCCCHHHHHCCCHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
SSMLMDASFRAALENASNEEEIVRLLAAKESEEEEPSLGTASADNGRKVLAVTACPTGIA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHH
HTYMAADALKAKAAEMGVMIKVETNGSDGVKNALTAQEIEDAAAIIVAADKQVEMDRFDG
HHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEEECCCCCCHHHCCC
KHVIQVPVAQAIRQPETLIEQALRQDAPIYRASGAPQGGAGAAKPRTGFYKHLMNGVSNM
CEEEEEHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LPFVVGGGILIALSFTFGIKAFDPNDPSYHPFAKALMDIGGGNAFALMIPVLAAFIAMSI
HHHHHCCHHHEEEEHHHCEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ADRPGFAPGMVGGFMAANGGAGFLGGLIAGFLAGYLVVGLRKLFSRLPQSLEGIKPVLLY
HCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
PLFGIFLTGIIMMYIVIDPVKALNEGLKHWLSGMGTANLLLLGAVLGGMMAVDMGGPINK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECCCCCCH
AAFTFGIAMIDAGNYAPHAAIMAGGMVPPLGLALATTFFKKKFTKAEREAGKTCYIMGAS
HHHHHEEHEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHH
FITEGAIPFAAADPMRVIPSIIVGSAVAGALTMLFGIGLPAPHGGIFVIPIVKGSAWLYI
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHH
LAILIGSAVTALMVGLWKKEVKE
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNITDLLTKETIILALRAQTKSEVIDELAAKLAEVGAVSDVEAFKQVIWAREKQSTTGVG
CCHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCC
EGIAIPHAKTAAVKRPAVAFGRSAEGIDYESLDGKPSHLFFMIAAPEGGEQTHLQALARL
CCCCCCCCHHHHHCCCHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
SSMLMDASFRAALENASNEEEIVRLLAAKESEEEEPSLGTASADNGRKVLAVTACPTGIA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHH
HTYMAADALKAKAAEMGVMIKVETNGSDGVKNALTAQEIEDAAAIIVAADKQVEMDRFDG
HHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEEECCCCCCHHHCCC
KHVIQVPVAQAIRQPETLIEQALRQDAPIYRASGAPQGGAGAAKPRTGFYKHLMNGVSNM
CEEEEEHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LPFVVGGGILIALSFTFGIKAFDPNDPSYHPFAKALMDIGGGNAFALMIPVLAAFIAMSI
HHHHHCCHHHEEEEHHHCEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ADRPGFAPGMVGGFMAANGGAGFLGGLIAGFLAGYLVVGLRKLFSRLPQSLEGIKPVLLY
HCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
PLFGIFLTGIIMMYIVIDPVKALNEGLKHWLSGMGTANLLLLGAVLGGMMAVDMGGPINK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECCCCCCH
AAFTFGIAMIDAGNYAPHAAIMAGGMVPPLGLALATTFFKKKFTKAEREAGKTCYIMGAS
HHHHHEEHEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHH
FITEGAIPFAAADPMRVIPSIIVGSAVAGALTMLFGIGLPAPHGGIFVIPIVKGSAWLYI
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHH
LAILIGSAVTALMVGLWKKEVKE
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]