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The map label for this gene is cbiA [H]

Identifier: 138895341

GI number: 138895341

Start: 1775178

End: 1776542

Strand: Reverse

Name: cbiA [H]

Synonym: GTNG_1685

Alternate gene names: 138895341

Gene position: 1776542-1775178 (Counterclockwise)

Preceding gene: 138895342

Following gene: 138895340

Centisome position: 50.04

GC content: 61.17

Gene sequence:

>1365_bases
ATGCGACGGCTTGTCATCGCTGCGCCAGGAAGCGGTGCCGGCAAAACGACCGTGACGCTTGGATTGATGGCGGCCATGAG
GCAGCAAGGATATACGGTGCAAGGGTTTAAATGCGGCCCGGACTACATCGATCCGACTTACCATACGGCTGTGACCGGCC
GGCCGGCGCGCAACTTGGACAGTTGGATGATGGGAAGCGAAGCGGTCAAAACGGTGCTCGCCAACGGTTGTCAAGGGGCT
GATATCGCCATCATCGAGGGGGTGATGGGGCTGTTTGACGGGAAACAGCCGCTTTCTGACGAGGGGTCGACGGCTGAAAT
CGCCGTGTTGACCGAAAGCCCGGTGCTGCTTGTCGTCGATTGTTCCGGCATGGCCCGCAGCGCCGCCGCCATCGTCCATG
GGTTTCAAACGTTTCGCCCCGATGTGCGCCTCGCCGGCGTATTTGCCAACCGCGTCGGCAGCGAAGGGCATTTTCGGCTC
GTCAAAGCGGCGGTCGAGCAAACGTGCGGGGTGCCGGTCGTCGGGTTTCTCACGCAAGACGAAGCGTTGGCGCTGCCAGA
GCGCCATTTAGGGCTCGTGCCGTCGGTGGAGCGCGGCGAACTGGATTCGTTTTTTGCCGAACTGGGGAGAAAGGTGGCGC
GCACGATCGATTGGGAGACGCTCCTTTCGATTGCAGAAGCGCCAGCCCTTTGTTCTCCGGCGCCGCTCATTCGCCCTTCG
CGGCCGTATCGCGTGCGCGTGGCGGTTGCCAAAGATGCCGCCTTTCATTTTTACTATCCGGAGAATCTGGAGATGCTTTC
TGCCTGCGGCGCGGAGCTTGTCTACTTTTCTCCGCTCGCCGGCGAGCCGCTTCCGGATGGGGTGAACGGATTGTATATCG
GCGGCGGGTTTCCGGAAGAGTTTGCCGCCGAGCTCGCCAGGCAAGCCGCGGTCAAACAGTCGATCCGCGCCGCCATCGAA
CACGGGTTGCCGACGTTGGCCGAATGCGGCGGGTTTATGTTTCTCACCGAACAGCTTGTTGCGACGGACGGTGCGGCCTA
TGAGATGGCGGGCGTCATCCCGGGGAAGGTCGTGATGAAGACGAAGCTCGCGGCGCTTGGCTACCGCGAAGTGCGCGGTC
GAAATGGAAATTTTCTATTGCCGGAAGGAGAAACAGCGCGCGGGCATGAATTTCACTATTCCGTGTACGAACCGCGGGGC
GAGGCGCCGTTTGCCTACGAAACGAGCGGCCGGAAAGGAACGAAGCCTGACGGTTATTTGGCGCACCGGCTTGTCGCCGG
CTATGTCCATTTTCATTTCGCGTCCGCCCCGGCGATGGTTGAGCGGTGGCTCGCCGAATGCGAGAAGGTGACCATCAATG
GCTAA

Upstream 100 bases:

>100_bases
ACAGCGGGGCCGATCGAATGGCGCTCGTGAAAAAGAAATCGGGTAACGTGACGATTTCGGTGGCACTGATCGATCACAGA
CGCAGAAAGGAGAGCGAGCC

Downstream 100 bases:

>100_bases
GACGCTGCCGATTATGTTTCAAGGCACCCATTCTGATGCCGGCAAAAGCGTCATCGCCACCGCGTTTTGCCGCATGTTCG
CCCAAGACGGCTGGAAGACG

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MRRLVIAAPGSGAGKTTVTLGLMAAMRQQGYTVQGFKCGPDYIDPTYHTAVTGRPARNLDSWMMGSEAVKTVLANGCQGA
DIAIIEGVMGLFDGKQPLSDEGSTAEIAVLTESPVLLVVDCSGMARSAAAIVHGFQTFRPDVRLAGVFANRVGSEGHFRL
VKAAVEQTCGVPVVGFLTQDEALALPERHLGLVPSVERGELDSFFAELGRKVARTIDWETLLSIAEAPALCSPAPLIRPS
RPYRVRVAVAKDAAFHFYYPENLEMLSACGAELVYFSPLAGEPLPDGVNGLYIGGGFPEEFAAELARQAAVKQSIRAAIE
HGLPTLAECGGFMFLTEQLVATDGAAYEMAGVIPGKVVMKTKLAALGYREVRGRNGNFLLPEGETARGHEFHYSVYEPRG
EAPFAYETSGRKGTKPDGYLAHRLVAGYVHFHFASAPAMVERWLAECEKVTING

Sequences:

>Translated_454_residues
MRRLVIAAPGSGAGKTTVTLGLMAAMRQQGYTVQGFKCGPDYIDPTYHTAVTGRPARNLDSWMMGSEAVKTVLANGCQGA
DIAIIEGVMGLFDGKQPLSDEGSTAEIAVLTESPVLLVVDCSGMARSAAAIVHGFQTFRPDVRLAGVFANRVGSEGHFRL
VKAAVEQTCGVPVVGFLTQDEALALPERHLGLVPSVERGELDSFFAELGRKVARTIDWETLLSIAEAPALCSPAPLIRPS
RPYRVRVAVAKDAAFHFYYPENLEMLSACGAELVYFSPLAGEPLPDGVNGLYIGGGFPEEFAAELARQAAVKQSIRAAIE
HGLPTLAECGGFMFLTEQLVATDGAAYEMAGVIPGKVVMKTKLAALGYREVRGRNGNFLLPEGETARGHEFHYSVYEPRG
EAPFAYETSGRKGTKPDGYLAHRLVAGYVHFHFASAPAMVERWLAECEKVTING
>Mature_454_residues
MRRLVIAAPGSGAGKTTVTLGLMAAMRQQGYTVQGFKCGPDYIDPTYHTAVTGRPARNLDSWMMGSEAVKTVLANGCQGA
DIAIIEGVMGLFDGKQPLSDEGSTAEIAVLTESPVLLVVDCSGMARSAAAIVHGFQTFRPDVRLAGVFANRVGSEGHFRL
VKAAVEQTCGVPVVGFLTQDEALALPERHLGLVPSVERGELDSFFAELGRKVARTIDWETLLSIAEAPALCSPAPLIRPS
RPYRVRVAVAKDAAFHFYYPENLEMLSACGAELVYFSPLAGEPLPDGVNGLYIGGGFPEEFAAELARQAAVKQSIRAAIE
HGLPTLAECGGFMFLTEQLVATDGAAYEMAGVIPGKVVMKTKLAALGYREVRGRNGNFLLPEGETARGHEFHYSVYEPRG
EAPFAYETSGRKGTKPDGYLAHRLVAGYVHFHFASAPAMVERWLAECEKVTING

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 48640; Mature: 48640

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLVIAAPGSGAGKTTVTLGLMAAMRQQGYTVQGFKCGPDYIDPTYHTAVTGRPARNLD
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCCHH
SWMMGSEAVKTVLANGCQGADIAIIEGVMGLFDGKQPLSDEGSTAEIAVLTESPVLLVVD
HHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEE
CSGMARSAAAIVHGFQTFRPDVRLAGVFANRVGSEGHFRLVKAAVEQTCGVPVVGFLTQD
CCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECC
EALALPERHLGLVPSVERGELDSFFAELGRKVARTIDWETLLSIAEAPALCSPAPLIRPS
CHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCC
RPYRVRVAVAKDAAFHFYYPENLEMLSACGAELVYFSPLAGEPLPDGVNGLYIGGGFPEE
CCCEEEEEEECCCEEEEECCCCHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECCCCCHH
FAAELARQAAVKQSIRAAIEHGLPTLAECGGFMFLTEQLVATDGAAYEMAGVIPGKVVMK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCCEEECCCCCCHHHHH
TKLAALGYREVRGRNGNFLLPEGETARGHEFHYSVYEPRGEAPFAYETSGRKGTKPDGYL
HHHHHHCHHHHCCCCCCEECCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCHHH
AHRLVAGYVHFHFASAPAMVERWLAECEKVTING
HHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MRRLVIAAPGSGAGKTTVTLGLMAAMRQQGYTVQGFKCGPDYIDPTYHTAVTGRPARNLD
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCCHH
SWMMGSEAVKTVLANGCQGADIAIIEGVMGLFDGKQPLSDEGSTAEIAVLTESPVLLVVD
HHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEE
CSGMARSAAAIVHGFQTFRPDVRLAGVFANRVGSEGHFRLVKAAVEQTCGVPVVGFLTQD
CCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECC
EALALPERHLGLVPSVERGELDSFFAELGRKVARTIDWETLLSIAEAPALCSPAPLIRPS
CHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCC
RPYRVRVAVAKDAAFHFYYPENLEMLSACGAELVYFSPLAGEPLPDGVNGLYIGGGFPEE
CCCEEEEEEECCCEEEEECCCCHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECCCCCHH
FAAELARQAAVKQSIRAAIEHGLPTLAECGGFMFLTEQLVATDGAAYEMAGVIPGKVVMK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCCEEECCCCCCHHHHH
TKLAALGYREVRGRNGNFLLPEGETARGHEFHYSVYEPRGEAPFAYETSGRKGTKPDGYL
HHHHHHCHHHHCCCCCCEECCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCHHH
AHRLVAGYVHFHFASAPAMVERWLAECEKVTING
HHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9742225 [H]