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The map label for this gene is dapL [H]

Identifier: 138895330

GI number: 138895330

Start: 1764444

End: 1765628

Strand: Reverse

Name: dapL [H]

Synonym: GTNG_1674

Alternate gene names: 138895330

Gene position: 1765628-1764444 (Counterclockwise)

Preceding gene: 138895331

Following gene: 138895329

Centisome position: 49.73

GC content: 53.5

Gene sequence:

>1185_bases
ATGAAAAAAGCGAAACGGATGAATGCGTTTTCTTCGTCTATTTTTGCTGAATTGTCGGCATATTGCCAAAAGCGGCGCCA
TCTTCATGACGAATGGATCGACTTAAGCGTCGGCAGCCCGGATTTGCCGCCGGCGCCGTTTGTGCGTGAGGCGATTGCCC
GCTACGCCGAGGAGCCGAACGCCTACGGATATACATTAAAAGGCATTCGTGAATTTCATGAAGCGGTCGCTGATTATTAC
CGGACGACGCACGGTGTCGTGTTGAATCCGGAGACGGAAGTGACGTATGTCATCGGGTCACAAGATGGTCTTGTCCATTT
GCCGATGGTGTTTGCTGATCCGGGTGATGTCATTTTAGTGCCGGATCCTGGATATCCAGCGTATGCCACCGGCGTAGCGA
TGGCCGAAGCGGAGCCATACTTTATGCCCTTAAAGGAAGAAAACGGCTTTTTGCCCGATTTGCGTGCGATTCCAGAGGAG
ATCGCCAAACGGGCGGCGATTATGTTTCTTAACTTTCCGGGCAATCCAGTGCCCGCCCTCGCGACTGAATCGTTTTATCG
TGAAGTCGTCGAGTTTGCGAAGCGGTACGACGTGCTTGTCGTCTCTGATTTTGCCTATGGTGAGCTGTATTATGATGGAA
ACAAACCAGTGAGCTTCCTTTCCGTTCCCGGGGCGAAAGACGTCGGGGTGGAAATGAACTCGCTGTCAAAAAGCTATAAC
ATGGCTGGTTGTCGAATCGGCTATTTGTGCGGCAACGCTGACGTGATTCGCGAGTTTGCCGCGTTTAAATCGAATTTAGA
TTACGGCATTTTTTGGCCAATTCAAAAAGCAGCCGCGGAAGTGCTTCGCTATGGAGGGGACTTTTGCGCCGAAAGCCGCG
CCATTTACCAATCGCGCCGCAACGCGCTTGTCAGTGGGTTGGCCGACATCGGCTGGACGGTCGACTGTCCGCCGGCTGGC
ATGTTCGTATGGGCGAAGATTCCCGTTGGGTTTACATCGCTCTCGTTCACAAAGGAACTCATCGACCGTGCTGGAGTCGT
TGTGACGCCTGGGCATGCGTTTGGACCGAGCGGTGAAGGTTATGTGCGCATCGCTCTCGTTCAGCCGGAAGATACGTTGC
GCCGTGCCGTTGAGAAACTGCGGGCGAGCGGTTTGTTCGAGCGGTTGGCTGCTGACCAACGATAA

Upstream 100 bases:

>100_bases
CTCCTTGAACATATGGTACACTATTCATATAACCATAGTATATACCAAGAAAAACAAAAAGGAAAAGCGGTTTTTGTCTT
GGCAAGGGAGAGGAAGAATA

Downstream 100 bases:

>100_bases
CGGAGGTGGGACGCGATGAAGCTACCGGCATGGCTTCGAAAAACGCTTGTTGCCGCGATTACTGTCTGCACATTTGGCCT
TGTGACACCACCTGCCTCGC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKKAKRMNAFSSSIFAELSAYCQKRRHLHDEWIDLSVGSPDLPPAPFVREAIARYAEEPNAYGYTLKGIREFHEAVADYY
RTTHGVVLNPETEVTYVIGSQDGLVHLPMVFADPGDVILVPDPGYPAYATGVAMAEAEPYFMPLKEENGFLPDLRAIPEE
IAKRAAIMFLNFPGNPVPALATESFYREVVEFAKRYDVLVVSDFAYGELYYDGNKPVSFLSVPGAKDVGVEMNSLSKSYN
MAGCRIGYLCGNADVIREFAAFKSNLDYGIFWPIQKAAAEVLRYGGDFCAESRAIYQSRRNALVSGLADIGWTVDCPPAG
MFVWAKIPVGFTSLSFTKELIDRAGVVVTPGHAFGPSGEGYVRIALVQPEDTLRRAVEKLRASGLFERLAADQR

Sequences:

>Translated_394_residues
MKKAKRMNAFSSSIFAELSAYCQKRRHLHDEWIDLSVGSPDLPPAPFVREAIARYAEEPNAYGYTLKGIREFHEAVADYY
RTTHGVVLNPETEVTYVIGSQDGLVHLPMVFADPGDVILVPDPGYPAYATGVAMAEAEPYFMPLKEENGFLPDLRAIPEE
IAKRAAIMFLNFPGNPVPALATESFYREVVEFAKRYDVLVVSDFAYGELYYDGNKPVSFLSVPGAKDVGVEMNSLSKSYN
MAGCRIGYLCGNADVIREFAAFKSNLDYGIFWPIQKAAAEVLRYGGDFCAESRAIYQSRRNALVSGLADIGWTVDCPPAG
MFVWAKIPVGFTSLSFTKELIDRAGVVVTPGHAFGPSGEGYVRIALVQPEDTLRRAVEKLRASGLFERLAADQR
>Mature_394_residues
MKKAKRMNAFSSSIFAELSAYCQKRRHLHDEWIDLSVGSPDLPPAPFVREAIARYAEEPNAYGYTLKGIREFHEAVADYY
RTTHGVVLNPETEVTYVIGSQDGLVHLPMVFADPGDVILVPDPGYPAYATGVAMAEAEPYFMPLKEENGFLPDLRAIPEE
IAKRAAIMFLNFPGNPVPALATESFYREVVEFAKRYDVLVVSDFAYGELYYDGNKPVSFLSVPGAKDVGVEMNSLSKSYN
MAGCRIGYLCGNADVIREFAAFKSNLDYGIFWPIQKAAAEVLRYGGDFCAESRAIYQSRRNALVSGLADIGWTVDCPPAG
MFVWAKIPVGFTSLSFTKELIDRAGVVVTPGHAFGPSGEGYVRIALVQPEDTLRRAVEKLRASGLFERLAADQR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=412, Percent_Identity=22.0873786407767, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI56713254, Length=412, Percent_Identity=22.0873786407767, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI95147551, Length=417, Percent_Identity=22.5419664268585, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI169881279, Length=417, Percent_Identity=22.5419664268585, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI169881281, Length=299, Percent_Identity=22.4080267558528, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI4507369, Length=370, Percent_Identity=23.7837837837838, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1788722, Length=385, Percent_Identity=40.2597402597403, Blast_Score=281, Evalue=6e-77,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=23.3160621761658, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788627, Length=229, Percent_Identity=26.6375545851528, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71994476, Length=420, Percent_Identity=23.3333333333333, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994472, Length=420, Percent_Identity=23.3333333333333, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=392, Percent_Identity=22.7040816326531, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17567663, Length=384, Percent_Identity=25.5208333333333, Blast_Score=96, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=388, Percent_Identity=21.6494845360825, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573069, Length=412, Percent_Identity=24.7572815533981, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24646114, Length=412, Percent_Identity=24.7572815533981, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28573067, Length=412, Percent_Identity=24.7572815533981, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28573065, Length=412, Percent_Identity=24.7572815533981, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI18859735, Length=372, Percent_Identity=23.1182795698925, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43508; Mature: 43508

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAKRMNAFSSSIFAELSAYCQKRRHLHDEWIDLSVGSPDLPPAPFVREAIARYAEEPN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCHHHHHHHHHHHCCCC
AYGYTLKGIREFHEAVADYYRTTHGVVLNPETEVTYVIGSQDGLVHLPMVFADPGDVILV
CCCEEHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEECCCCEEEEEEEEECCCCEEEE
PDPGYPAYATGVAMAEAEPYFMPLKEENGFLPDLRAIPEEIAKRAAIMFLNFPGNPVPAL
CCCCCCHHHHCEEEECCCCCEEEECCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCHH
ATESFYREVVEFAKRYDVLVVSDFAYGELYYDGNKPVSFLSVPGAKDVGVEMNSLSKSYN
HHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHCCCC
MAGCRIGYLCGNADVIREFAAFKSNLDYGIFWPIQKAAAEVLRYGGDFCAESRAIYQSRR
CCCCEEEEEECCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHH
NALVSGLADIGWTVDCPPAGMFVWAKIPVGFTSLSFTKELIDRAGVVVTPGHAFGPSGEG
HHHHHHHHHCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCC
YVRIALVQPEDTLRRAVEKLRASGLFERLAADQR
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKAKRMNAFSSSIFAELSAYCQKRRHLHDEWIDLSVGSPDLPPAPFVREAIARYAEEPN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCHHHHHHHHHHHCCCC
AYGYTLKGIREFHEAVADYYRTTHGVVLNPETEVTYVIGSQDGLVHLPMVFADPGDVILV
CCCEEHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEECCCCEEEEEEEEECCCCEEEE
PDPGYPAYATGVAMAEAEPYFMPLKEENGFLPDLRAIPEEIAKRAAIMFLNFPGNPVPAL
CCCCCCHHHHCEEEECCCCCEEEECCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCHH
ATESFYREVVEFAKRYDVLVVSDFAYGELYYDGNKPVSFLSVPGAKDVGVEMNSLSKSYN
HHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHCCCC
MAGCRIGYLCGNADVIREFAAFKSNLDYGIFWPIQKAAAEVLRYGGDFCAESRAIYQSRR
CCCCEEEEEECCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHH
NALVSGLADIGWTVDCPPAGMFVWAKIPVGFTSLSFTKELIDRAGVVVTPGHAFGPSGEG
HHHHHHHHHCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCC
YVRIALVQPEDTLRRAVEKLRASGLFERLAADQR
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA