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The map label for this gene is thrC [H]

Identifier: 138895314

GI number: 138895314

Start: 1750485

End: 1751696

Strand: Reverse

Name: thrC [H]

Synonym: GTNG_1658

Alternate gene names: 138895314

Gene position: 1751696-1750485 (Counterclockwise)

Preceding gene: 138895317

Following gene: 138895313

Centisome position: 49.34

GC content: 53.88

Gene sequence:

>1212_bases
ATGTCATTTAGTTACGCATCCCATCTCTACTGCTCGAAATGCGAACGTACATATGATGTCGATCACGTGCACCAGCTTTG
CGAATGCGGTTCTCCACTTCTAGTCGCCTATGATTTGGAAGCGATGCGCCAAGAAGTGGCACGGGAAGCGCTCAAGGAAC
GTGAACCGAGCTTATGGCGGTATCATGAGCTATTGCCGGTGAAACATCCCAAACATATCGTCTCTTTAGGTGAAGGGATG
ACCCCGCTTGTACGAATGGCGCGCCTTGGCCGGAACATCGGGATTGATTCACTTTATATGAAAGACGAAGGGGTCATTCC
AACGGGGACGTTTAAAGCTCGCGGGGCGGCGGTCGGCGTTTCCAAAGCGAAAGAATTGGGGGTCGAACAGCTTGCTATGC
CGACAAACGGCAACGCAGGGGCGGCGTGGTCGCTTTATGCTTCTCGAGCCGGCATTCGTGCGACGGTGGTTATGCCGGTG
GATGCACCGGAGTTGACGCGCAAGGAATGTGCCATCGCAGGGGCGGAATTATATTTAGTCAACGGCTTGATCAGCGATGC
TGGACAAATCGTGGCGAAAGCGATCCGTGAATACGGTTGGTACGATGCTTCTACATTGAAAGAACCGTATCGGATTGAAG
GAAAGAAAACGATGGGACTTGAGATTGCCGAGCAGCTCTCTTGGCAGCTTCCGGATGTCATCTTGTATCCGACCGGGGGC
GGCGTTGGGCTCATTGGCATTTACAAGGCAATCAAAGAACTGCAGGCGCTTGGTTGGGTAAGCGGCAAGATGCCGCGGCT
TGTCGCTGTGCAAGCCGAGCATTGCGCACCGATTGTGAAGGCATGGAACGAGAAAAAGCGTGAGTCGGAATTTTGGCCGA
ACTCTCATACGGTGGCGTTTGGCATTAACGTGCCAAAAGCGTTTGGCGACTTTCTTGTGCTTGAGGCGGTGTATGAGACG
GATGGCTGTGCGATTGCTATCGACGATGAGGCGATTTTGGCACAACAGCAGATGGTGGCAAAAGCGGAAGGGGCGTTCAT
TTGCCCGGAAGGAGCGGCGGCGTTTGCGGCGGCTCGCCAGCTGCGCGAAAGCGGTTGGATTCGTGACGGGGAGACCGTCG
TTGTGCTAAATACTGGAACCGGATTGAAATACGCTGATATGGTCAATGTCAATCCGCCGGTACTCGAGCTGGGGGAGGAG
CTGATTAGATAA

Upstream 100 bases:

>100_bases
TAATGAAAAGGACGGGTGTGTCGTCAAGCCTCTACATAATAAGCTCACACCTGCTTAGCCGTCCAGTACAGACAAAGTAG
ACGGAAGGAGAGGACAACCG

Downstream 100 bases:

>100_bases
AGTTGACAACTAGTCGCGGCAAGTCGACTGTGCGGGAAACGAAAGCACAGCATGTTCGGTCAACTTGTCATCAAGCTGTT
AATCGTAGACAAAATGATAT

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSFSYASHLYCSKCERTYDVDHVHQLCECGSPLLVAYDLEAMRQEVAREALKEREPSLWRYHELLPVKHPKHIVSLGEGM
TPLVRMARLGRNIGIDSLYMKDEGVIPTGTFKARGAAVGVSKAKELGVEQLAMPTNGNAGAAWSLYASRAGIRATVVMPV
DAPELTRKECAIAGAELYLVNGLISDAGQIVAKAIREYGWYDASTLKEPYRIEGKKTMGLEIAEQLSWQLPDVILYPTGG
GVGLIGIYKAIKELQALGWVSGKMPRLVAVQAEHCAPIVKAWNEKKRESEFWPNSHTVAFGINVPKAFGDFLVLEAVYET
DGCAIAIDDEAILAQQQMVAKAEGAFICPEGAAAFAAARQLRESGWIRDGETVVVLNTGTGLKYADMVNVNPPVLELGEE
LIR

Sequences:

>Translated_403_residues
MSFSYASHLYCSKCERTYDVDHVHQLCECGSPLLVAYDLEAMRQEVAREALKEREPSLWRYHELLPVKHPKHIVSLGEGM
TPLVRMARLGRNIGIDSLYMKDEGVIPTGTFKARGAAVGVSKAKELGVEQLAMPTNGNAGAAWSLYASRAGIRATVVMPV
DAPELTRKECAIAGAELYLVNGLISDAGQIVAKAIREYGWYDASTLKEPYRIEGKKTMGLEIAEQLSWQLPDVILYPTGG
GVGLIGIYKAIKELQALGWVSGKMPRLVAVQAEHCAPIVKAWNEKKRESEFWPNSHTVAFGINVPKAFGDFLVLEAVYET
DGCAIAIDDEAILAQQQMVAKAEGAFICPEGAAAFAAARQLRESGWIRDGETVVVLNTGTGLKYADMVNVNPPVLELGEE
LIR
>Mature_402_residues
SFSYASHLYCSKCERTYDVDHVHQLCECGSPLLVAYDLEAMRQEVAREALKEREPSLWRYHELLPVKHPKHIVSLGEGMT
PLVRMARLGRNIGIDSLYMKDEGVIPTGTFKARGAAVGVSKAKELGVEQLAMPTNGNAGAAWSLYASRAGIRATVVMPVD
APELTRKECAIAGAELYLVNGLISDAGQIVAKAIREYGWYDASTLKEPYRIEGKKTMGLEIAEQLSWQLPDVILYPTGGG
VGLIGIYKAIKELQALGWVSGKMPRLVAVQAEHCAPIVKAWNEKKRESEFWPNSHTVAFGINVPKAFGDFLVLEAVYETD
GCAIAIDDEAILAQQQMVAKAEGAFICPEGAAAFAAARQLRESGWIRDGETVVVLNTGTGLKYADMVNVNPPVLELGEEL
IR

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71991565, Length=292, Percent_Identity=30.1369863013699, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 44006; Mature: 43875

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSYASHLYCSKCERTYDVDHVHQLCECGSPLLVAYDLEAMRQEVAREALKEREPSLWR
CCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHH
YHELLPVKHPKHIVSLGEGMTPLVRMARLGRNIGIDSLYMKDEGVIPTGTFKARGAAVGV
HHHHCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCEECH
SKAKELGVEQLAMPTNGNAGAAWSLYASRAGIRATVVMPVDAPELTRKECAIAGAELYLV
HHHHHCCHHHEECCCCCCCCCEEEEHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEE
NGLISDAGQIVAKAIREYGWYDASTLKEPYRIEGKKTMGLEIAEQLSWQLPDVILYPTGG
HHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEECCCCCCCHHHHHHHCCCCCCEEEEECCC
GVGLIGIYKAIKELQALGWVSGKMPRLVAVQAEHCAPIVKAWNEKKRESEFWPNSHTVAF
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
GINVPKAFGDFLVLEAVYETDGCAIAIDDEAILAQQQMVAKAEGAFICPEGAAAFAAARQ
ECCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHH
LRESGWIRDGETVVVLNTGTGLKYADMVNVNPPVLELGEELIR
HHHHCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
SFSYASHLYCSKCERTYDVDHVHQLCECGSPLLVAYDLEAMRQEVAREALKEREPSLWR
CCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHH
YHELLPVKHPKHIVSLGEGMTPLVRMARLGRNIGIDSLYMKDEGVIPTGTFKARGAAVGV
HHHHCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCEECH
SKAKELGVEQLAMPTNGNAGAAWSLYASRAGIRATVVMPVDAPELTRKECAIAGAELYLV
HHHHHCCHHHEECCCCCCCCCEEEEHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEE
NGLISDAGQIVAKAIREYGWYDASTLKEPYRIEGKKTMGLEIAEQLSWQLPDVILYPTGG
HHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEECCCCCCCHHHHHHHCCCCCCEEEEECCC
GVGLIGIYKAIKELQALGWVSGKMPRLVAVQAEHCAPIVKAWNEKKRESEFWPNSHTVAF
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
GINVPKAFGDFLVLEAVYETDGCAIAIDDEAILAQQQMVAKAEGAFICPEGAAAFAAARQ
ECCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHH
LRESGWIRDGETVVVLNTGTGLKYADMVNVNPPVLELGEELIR
HHHHCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]