Click here to switch to the map view.

The map label for this gene is atoS [H]

Identifier: 138895099

GI number: 138895099

Start: 1523451

End: 1524743

Strand: Reverse

Name: atoS [H]

Synonym: GTNG_1437

Alternate gene names: 138895099

Gene position: 1524743-1523451 (Counterclockwise)

Preceding gene: 138895100

Following gene: 138895098

Centisome position: 42.95

GC content: 48.8

Gene sequence:

>1293_bases
ATGAGATGTGTAGTTAAGGAGTTTGGAAGGATGAACGATCGATTGGTACAACAGCAAACTGAAGAGCTTGAACGAAAACT
GCGCGCTTATGAGCGGCTCATCGAAAAACTCCCGTTCCCATTCATGTTTACCGATTACTATTCCGGAACCACCATCGAAA
AAAGGCGCGGTGATGTCCAACCGCGCCTTTCGCCGGCTCGGATCGCCCCTGGAAAGGAAACAGAATGGCAGTGGGACATT
GACTTATATCGTGATGTGCCGTTTGAAAAAGTCGAAGCGTTTTTAACACCGCTGCTTGACCTTGTTCCGCACCATATCGT
CTTCGTCGACGATCATGGAATCATTACGCTTTGCAATTTACAAGCGGCCATGGATACCGGCGTCGACCGCGATGCCATCA
TCGGCAAACATATTCGCGAGCTGCTGAAACTTCCCGATGAGCTAATCGCAACACTAGAATCGTTGGAAAAGCGCGAGCCT
CTTTACAATCGCGAAGTGCTCGATCGCTTTTACGGCATCGTCAACACCCGCTTTATTTATAATGATGACGGATCGGTCAA
ACGGGTCATTAGCATATTCCAATCGCTCAACATGATGAAAGAGACGGAAAAATTGGCTGCCGCAGGTCGCATTGCGGCCG
GCATCGCTCATGAAATCCGCAATCCGCTGACGACAGTACGCGGCTATTTGCAGTTGTTGAAAAACGATTTGCCAGATCGC
ATTACATCGCTCGTTGAGCGGCTGCTCATCCCCGAACTCGACCGGGCGAATGACATCATTACCGACTTTTTAAATATCGC
CAAACCACGGGACGTGAAAATGGAGACGTTCAACTTGCACCGCTTTTTGCGTGATGACGTCGGTGTTCTGCTGCAAAGTG
AGGCGCTGCTTCACAACGTCAACGTCCATTTTGATCTTGATGAACAGCTTGACGATTATGAAATGAATGGCGACCGCAGC
CAACTGCTGCAAGTGTTTTTAAACTTATTCCGCAACGCCATCGAGGCGAAAGTCGCAAAGACAATGAATGTGAAAGTCAG
CAGCCGGAAAGTAAACCATATCGTCCAGCTTCGCTTCTGCGACGACGGGCCCGGCATTCCGTCACCGGTCATCGACCATA
TTTTTGAGCCATTTTTCTCGACGAAAGAAACGGGAACAGGGCTCGGTCTTTCGCTGTCGAAAAAAATTGTCGAACTGCAT
CGAGGAACGATAAAAGTGCAAAGTGACGCATGTGGCACTTGTTTTCTTATGGAATTTCCGCTTCGTAGCCAGCCGCCTTA
TTTTTCGTCATAA

Upstream 100 bases:

>100_bases
GAAACAGTTATCAACGGTGCCAACCGTCATCGGCCGTCTTAGTGCCCGACATAGGGACGTTCGTCATAGCCAAAGGCGAT
TCACTTTTGTAAAATAGGAA

Downstream 100 bases:

>100_bases
GCGGCTTCTACAGGGGGATCGCTCCCCCTGGCTCGGGGGAGACGGAAAGATTGATGATTTAGCACAATGTGTTGTTTTTA
GACAAAGGAGGAGCCATGAT

Product: sporulation kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MRCVVKEFGRMNDRLVQQQTEELERKLRAYERLIEKLPFPFMFTDYYSGTTIEKRRGDVQPRLSPARIAPGKETEWQWDI
DLYRDVPFEKVEAFLTPLLDLVPHHIVFVDDHGIITLCNLQAAMDTGVDRDAIIGKHIRELLKLPDELIATLESLEKREP
LYNREVLDRFYGIVNTRFIYNDDGSVKRVISIFQSLNMMKETEKLAAAGRIAAGIAHEIRNPLTTVRGYLQLLKNDLPDR
ITSLVERLLIPELDRANDIITDFLNIAKPRDVKMETFNLHRFLRDDVGVLLQSEALLHNVNVHFDLDEQLDDYEMNGDRS
QLLQVFLNLFRNAIEAKVAKTMNVKVSSRKVNHIVQLRFCDDGPGIPSPVIDHIFEPFFSTKETGTGLGLSLSKKIVELH
RGTIKVQSDACGTCFLMEFPLRSQPPYFSS

Sequences:

>Translated_430_residues
MRCVVKEFGRMNDRLVQQQTEELERKLRAYERLIEKLPFPFMFTDYYSGTTIEKRRGDVQPRLSPARIAPGKETEWQWDI
DLYRDVPFEKVEAFLTPLLDLVPHHIVFVDDHGIITLCNLQAAMDTGVDRDAIIGKHIRELLKLPDELIATLESLEKREP
LYNREVLDRFYGIVNTRFIYNDDGSVKRVISIFQSLNMMKETEKLAAAGRIAAGIAHEIRNPLTTVRGYLQLLKNDLPDR
ITSLVERLLIPELDRANDIITDFLNIAKPRDVKMETFNLHRFLRDDVGVLLQSEALLHNVNVHFDLDEQLDDYEMNGDRS
QLLQVFLNLFRNAIEAKVAKTMNVKVSSRKVNHIVQLRFCDDGPGIPSPVIDHIFEPFFSTKETGTGLGLSLSKKIVELH
RGTIKVQSDACGTCFLMEFPLRSQPPYFSS
>Mature_430_residues
MRCVVKEFGRMNDRLVQQQTEELERKLRAYERLIEKLPFPFMFTDYYSGTTIEKRRGDVQPRLSPARIAPGKETEWQWDI
DLYRDVPFEKVEAFLTPLLDLVPHHIVFVDDHGIITLCNLQAAMDTGVDRDAIIGKHIRELLKLPDELIATLESLEKREP
LYNREVLDRFYGIVNTRFIYNDDGSVKRVISIFQSLNMMKETEKLAAAGRIAAGIAHEIRNPLTTVRGYLQLLKNDLPDR
ITSLVERLLIPELDRANDIITDFLNIAKPRDVKMETFNLHRFLRDDVGVLLQSEALLHNVNVHFDLDEQLDDYEMNGDRS
QLLQVFLNLFRNAIEAKVAKTMNVKVSSRKVNHIVQLRFCDDGPGIPSPVIDHIFEPFFSTKETGTGLGLSLSKKIVELH
RGTIKVQSDACGTCFLMEFPLRSQPPYFSS

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=333, Percent_Identity=31.5315315315315, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790300, Length=348, Percent_Identity=29.3103448275862, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786600, Length=345, Percent_Identity=25.2173913043478, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786783, Length=223, Percent_Identity=29.1479820627803, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=26.4227642276423, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI145693157, Length=279, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788393, Length=223, Percent_Identity=25.1121076233184, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49485; Mature: 49485

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCVVKEFGRMNDRLVQQQTEELERKLRAYERLIEKLPFPFMFTDYYSGTTIEKRRGDVQ
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHCCCCC
PRLSPARIAPGKETEWQWDIDLYRDVPFEKVEAFLTPLLDLVPHHIVFVDDHGIITLCNL
CCCCCCCCCCCCCCCEEECHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEH
QAAMDTGVDRDAIIGKHIRELLKLPDELIATLESLEKREPLYNREVLDRFYGIVNTRFIY
HHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCEEEE
NDDGSVKRVISIFQSLNMMKETEKLAAAGRIAAGIAHEIRNPLTTVRGYLQLLKNDLPDR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ITSLVERLLIPELDRANDIITDFLNIAKPRDVKMETFNLHRFLRDDVGVLLQSEALLHNV
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
NVHFDLDEQLDDYEMNGDRSQLLQVFLNLFRNAIEAKVAKTMNVKVSSRKVNHIVQLRFC
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEHHHHHCEEEEEEEE
DDGPGIPSPVIDHIFEPFFSTKETGTGLGLSLSKKIVELHRGTIKVQSDACGTCFLMEFP
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCEEEEEECC
LRSQPPYFSS
CCCCCCCCCC
>Mature Secondary Structure
MRCVVKEFGRMNDRLVQQQTEELERKLRAYERLIEKLPFPFMFTDYYSGTTIEKRRGDVQ
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHCCCCC
PRLSPARIAPGKETEWQWDIDLYRDVPFEKVEAFLTPLLDLVPHHIVFVDDHGIITLCNL
CCCCCCCCCCCCCCCEEECHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEH
QAAMDTGVDRDAIIGKHIRELLKLPDELIATLESLEKREPLYNREVLDRFYGIVNTRFIY
HHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCEEEE
NDDGSVKRVISIFQSLNMMKETEKLAAAGRIAAGIAHEIRNPLTTVRGYLQLLKNDLPDR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ITSLVERLLIPELDRANDIITDFLNIAKPRDVKMETFNLHRFLRDDVGVLLQSEALLHNV
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
NVHFDLDEQLDDYEMNGDRSQLLQVFLNLFRNAIEAKVAKTMNVKVSSRKVNHIVQLRFC
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEHHHHHCEEEEEEEE
DDGPGIPSPVIDHIFEPFFSTKETGTGLGLSLSKKIVELHRGTIKVQSDACGTCFLMEFP
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCEEEEEECC
LRSQPPYFSS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]