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The map label for this gene is ycgM [C]

Identifier: 138895048

GI number: 138895048

Start: 1473076

End: 1473855

Strand: Direct

Name: ycgM [C]

Synonym: GTNG_1386

Alternate gene names: 138895048

Gene position: 1473076-1473855 (Clockwise)

Preceding gene: 138895047

Following gene: 138895049

Centisome position: 41.49

GC content: 52.56

Gene sequence:

>780_bases
ATGAAGTTTGCCCGTTTTATCGCCGCTGGCGAGATTCGCACCGGTGTAGTGAGCGGCGAAGTCATCCGTGAAATTGAAGG
AGACATGTTTACGGCTTGGGATTATACCGGCAACGTATTTCACTGCAATGACGTTTCGTTTGTGGCACCGCTTGTGCCGC
GCCATGTGATCGGCATTGGCGCTAACTACGTGGCAGCGCGTGAACAACTGCCGGCTCAACTGCCGGACATTCCTGTCTTT
TTCTTTAAACCGTCTTCATCGGTCATCGGTCCGGAAGCGGACATTGTCATTCCAAACGGAATCGACGAAGTGAAGTTTGA
ATCTGAGCTGGCTGTTGTCATCGGCAAAGAGGCAAAACAAGTGAGCGAGGAGAACGTATGGGCGTACATTTTTGGTTATA
CGGTCGCCAACGATGTCACTGCGCCACAATTTTTCCATCCAGATGGGCATTGGACGGTTGGAAAATCGTTCGATACGTTC
ACACCGCTAGGGCCGGTTATTGAAACGGAACTCGAGCCACGGTCGGTGTCGGTTAAAGCGCGGGTCAATGGCGAGGAAAA
ACAAAACAGTCCGACCGAGCTGATGATTATCTCGATCAGCAAAATGATTTCGTATTTGTCTTCTGTGATGACGCTGCAGC
CGGGTGATGTCATTTTAACGGGAAGCCCAGTTGGCGCTGAGCTTGTCGGTCCGGGAACTGTCATTGAGTGCGAAGTGGAC
GGCATCGGCACGCTCCGCAATACGTTCGTCGCCGCCAAAGCGCCGGCCGTCTCTTCCTAG

Upstream 100 bases:

>100_bases
CGGTCGCTTCTGCTGTTGCCCGTGCTGCCATCGAGACCGGGGTGGCTCGGAACAAGGAGAAATATGAGGGAAAAACCTTG
TTAGAGAGGGGTAACCACCA

Downstream 100 bases:

>100_bases
CAAGGATCACACGCTATGTTCCGCTGTTTAGGAGAGGCGCTTATCGGCGTAGTGCCCGACGTGACACGGCGTCGCCTTCT
GTGCCCGCCGCTGCCGAGGC

Product: 2-keto-4-pentenoatehydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase (catechol pathway)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKFARFIAAGEIRTGVVSGEVIREIEGDMFTAWDYTGNVFHCNDVSFVAPLVPRHVIGIGANYVAAREQLPAQLPDIPVF
FFKPSSSVIGPEADIVIPNGIDEVKFESELAVVIGKEAKQVSEENVWAYIFGYTVANDVTAPQFFHPDGHWTVGKSFDTF
TPLGPVIETELEPRSVSVKARVNGEEKQNSPTELMIISISKMISYLSSVMTLQPGDVILTGSPVGAELVGPGTVIECEVD
GIGTLRNTFVAAKAPAVSS

Sequences:

>Translated_259_residues
MKFARFIAAGEIRTGVVSGEVIREIEGDMFTAWDYTGNVFHCNDVSFVAPLVPRHVIGIGANYVAAREQLPAQLPDIPVF
FFKPSSSVIGPEADIVIPNGIDEVKFESELAVVIGKEAKQVSEENVWAYIFGYTVANDVTAPQFFHPDGHWTVGKSFDTF
TPLGPVIETELEPRSVSVKARVNGEEKQNSPTELMIISISKMISYLSSVMTLQPGDVILTGSPVGAELVGPGTVIECEVD
GIGTLRNTFVAAKAPAVSS
>Mature_259_residues
MKFARFIAAGEIRTGVVSGEVIREIEGDMFTAWDYTGNVFHCNDVSFVAPLVPRHVIGIGANYVAAREQLPAQLPDIPVF
FFKPSSSVIGPEADIVIPNGIDEVKFESELAVVIGKEAKQVSEENVWAYIFGYTVANDVTAPQFFHPDGHWTVGKSFDTF
TPLGPVIETELEPRSVSVKARVNGEEKQNSPTELMIISISKMISYLSSVMTLQPGDVILTGSPVGAELVGPGTVIECEVD
GIGTLRNTFVAAKAPAVSS

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=225, Percent_Identity=36.4444444444444, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI156231349, Length=221, Percent_Identity=36.6515837104072, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI66348062, Length=195, Percent_Identity=31.7948717948718, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI13654274, Length=198, Percent_Identity=31.3131313131313, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI215422413, Length=195, Percent_Identity=31.7948717948718, Blast_Score=101, Evalue=5e-22,
Organism=Escherichia coli, GI1787428, Length=193, Percent_Identity=33.6787564766839, Blast_Score=108, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17557057, Length=188, Percent_Identity=35.6382978723404, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324161, Length=225, Percent_Identity=31.5555555555556, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28572127, Length=222, Percent_Identity=37.8378378378378, Blast_Score=140, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28571789, Length=198, Percent_Identity=37.8787878787879, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24663695, Length=220, Percent_Identity=33.1818181818182, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 27889; Mature: 27889

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFARFIAAGEIRTGVVSGEVIREIEGDMFTAWDYTGNVFHCNDVSFVAPLVPRHVIGIG
CCHHHEEECCCCEECEECHHHHHHHCCCEEEEEECCCCEEEECCCHHHHHHHHHHEEECC
ANYVAAREQLPAQLPDIPVFFFKPSSSVIGPEADIVIPNGIDEVKFESELAVVIGKEAKQ
CCHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCEEECCCCCCCEECCCEEEEECCCHHH
VSEENVWAYIFGYTVANDVTAPQFFHPDGHWTVGKSFDTFTPLGPVIETELEPRSVSVKA
HCCCCEEEEEEEEEEECCCCCCEEECCCCCEEECCCCCCCCCCCCCEECCCCCCEEEEEE
RVNGEEKQNSPTELMIISISKMISYLSSVMTLQPGDVILTGSPVGAELVGPGTVIECEVD
EECCCCCCCCCCEEEEEEHHHHHHHHHHHHEECCCCEEEECCCCCCEEECCCEEEEEEEC
GIGTLRNTFVAAKAPAVSS
CCCCHHHHEEEECCCCCCC
>Mature Secondary Structure
MKFARFIAAGEIRTGVVSGEVIREIEGDMFTAWDYTGNVFHCNDVSFVAPLVPRHVIGIG
CCHHHEEECCCCEECEECHHHHHHHCCCEEEEEECCCCEEEECCCHHHHHHHHHHEEECC
ANYVAAREQLPAQLPDIPVFFFKPSSSVIGPEADIVIPNGIDEVKFESELAVVIGKEAKQ
CCHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCEEECCCCCCCEECCCEEEEECCCHHH
VSEENVWAYIFGYTVANDVTAPQFFHPDGHWTVGKSFDTFTPLGPVIETELEPRSVSVKA
HCCCCEEEEEEEEEEECCCCCCEEECCCCCEEECCCCCCCCCCCCCEECCCCCCEEEEEE
RVNGEEKQNSPTELMIISISKMISYLSSVMTLQPGDVILTGSPVGAELVGPGTVIECEVD
EECCCCCCCCCCEEEEEEHHHHHHHHHHHHEECCCCEEEECCCCCCEEECCCEEEEEEEC
GIGTLRNTFVAAKAPAVSS
CCCCHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]