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The map label for this gene is mqo

Identifier: 138894912

GI number: 138894912

Start: 1321846

End: 1323351

Strand: Direct

Name: mqo

Synonym: GTNG_1250

Alternate gene names: 138894912

Gene position: 1321846-1323351 (Clockwise)

Preceding gene: 138894911

Following gene: 138894913

Centisome position: 37.23

GC content: 48.8

Gene sequence:

>1506_bases
ATGGGCAACAAACAAACCAAAACTGATGTGATCTTAATCGGCGCCGGCATTATGAGCGCCACGTTGGGAACGTTGTTAAA
AGAGTTGGCACCGGAGTGGGACATCACTGTATTTGAAAGACTGGAAGAAGCAGGAGTGGAAAGCTCCAACGAGTGGAACA
ATGCCGGAACAGGGCATGCGGCTCTTTGCGAGCTGAACTATACCGTTGAGAAGCCCGATGGGTCCATTGACATCAGCAAA
GCCATCAAAATCAATGAGCAATTTTACGTTTCCTTGCAGTTTTGGGCTTATTTAGTGAACAGCGGGGTGCTTCGTGATCC
AAAAGAGTTCATTCGTCCGTTGCCTCATATGAGCTTCGTGCAAGGGGAAGACAATGTCGCATTTTTGAAAAAGCGGTATG
AAACAATGGTGAATAACCCGCTGTTTAAAGGCATGGAATTTTCTGATGATCCGAAAAAGTTGGCCGAATGGATACCGCTC
ATGATGGAAAATCGCGTTGTGAACGAGCCGATCGCAGCTACGCGGATCGAATCAGGAACAGATGTGAACTTTGGGGCACT
GACGCGCAAACTGTTTGAGCATTTAAAACGGAAAAATGTCGAGATTCATTACCGTCATCATGTTGATGACATCAAGCGGA
CAAGCGACGGTCTATGGGAGTTAAAAGTGCGCGATTTAGATAGCGGCGCTGTTGAACGTCATGTGGCCAAATTTGTCTTC
ATTGGTGCTGGGGGAGGAAGCCTCCATCTGTTGCAAAAATCCGGTATTCCGGAAGGAAGAGGGATTGGCGGATTCCCGGT
CAGTGGATTGTTTATGGTGTGCAACAATCCGGATGTGGTTGAGCAGCACCATGCGAAAGTGTACGGCAAAGCGAAAGTCG
GCGCGCCGCCGATGTCGGTTCCGCATTTGGATACGCGGTTTATCAACAATCAAAAAATGTTGTTGTTTGGACCGTTTGCC
GGCTTCTCGCCGAAGTTTTTGAAAAACGGGTCGATGCTCGATTTATTTACATCGGTCAAACCGCATAACCTTTTGACGAT
GTTGGCGGCAGGCGTGAAAAATATGGCGCTTACCAATTACTTAATCCAGCAAGTGATGTTGTCGAAAGAACAACGCATGG
AAGAGTTGCGCGAGTTTGTTCCGACAGCCAAAAGCGAGGAATGGGATGTCATTGTTGCTGGCCAGCGCGTGCAAGTGATC
AAAGATACGGAAGCTGGCGGCAAAGGAACGTTGCAATTCGGTACAGAAGTCGTCCATGCGGCTGATGGTTCGATTGCGGC
GTTGCTTGGCGCCTCGCCAGGCGCTTCGACCGCGGTTCATGTCATGCTAGAAGTAATCACGAAATGTTTCCCGGAACGAA
TGAAAGAGTGGGAGCCGAAGGTGAGAGAAATGATTCCTTCCTACGGTGTATCGCTCATGAAAAACGAACGACTTTTGCAC
GACGTTCAAGCCGCAACAGCGGAGATGCTCGGTTTAAGAGAAGGACTGGCATTGCAGCTCGTTTGA

Upstream 100 bases:

>100_bases
TGTGTAACCGCCCTCAACAAGGTAAACGGGGGTATCAGTGGAATCATTTCGAGCGGTCGCTCACCGCTTTTGTAAATATT
AGTAGATAGGGATGGTAAAC

Downstream 100 bases:

>100_bases
ATGTGTGTGATTCAGTAGATTGCCGGCCTGTGGCGCTCAGCGCCCATAAACAACAAGCTGCCCGAAGACGAAGGGCAGCT
TTTTTTTAGCAGAACTTTCC

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MGNKQTKTDVILIGAGIMSATLGTLLKELAPEWDITVFERLEEAGVESSNEWNNAGTGHAALCELNYTVEKPDGSIDISK
AIKINEQFYVSLQFWAYLVNSGVLRDPKEFIRPLPHMSFVQGEDNVAFLKKRYETMVNNPLFKGMEFSDDPKKLAEWIPL
MMENRVVNEPIAATRIESGTDVNFGALTRKLFEHLKRKNVEIHYRHHVDDIKRTSDGLWELKVRDLDSGAVERHVAKFVF
IGAGGGSLHLLQKSGIPEGRGIGGFPVSGLFMVCNNPDVVEQHHAKVYGKAKVGAPPMSVPHLDTRFINNQKMLLFGPFA
GFSPKFLKNGSMLDLFTSVKPHNLLTMLAAGVKNMALTNYLIQQVMLSKEQRMEELREFVPTAKSEEWDVIVAGQRVQVI
KDTEAGGKGTLQFGTEVVHAADGSIAALLGASPGASTAVHVMLEVITKCFPERMKEWEPKVREMIPSYGVSLMKNERLLH
DVQAATAEMLGLREGLALQLV

Sequences:

>Translated_501_residues
MGNKQTKTDVILIGAGIMSATLGTLLKELAPEWDITVFERLEEAGVESSNEWNNAGTGHAALCELNYTVEKPDGSIDISK
AIKINEQFYVSLQFWAYLVNSGVLRDPKEFIRPLPHMSFVQGEDNVAFLKKRYETMVNNPLFKGMEFSDDPKKLAEWIPL
MMENRVVNEPIAATRIESGTDVNFGALTRKLFEHLKRKNVEIHYRHHVDDIKRTSDGLWELKVRDLDSGAVERHVAKFVF
IGAGGGSLHLLQKSGIPEGRGIGGFPVSGLFMVCNNPDVVEQHHAKVYGKAKVGAPPMSVPHLDTRFINNQKMLLFGPFA
GFSPKFLKNGSMLDLFTSVKPHNLLTMLAAGVKNMALTNYLIQQVMLSKEQRMEELREFVPTAKSEEWDVIVAGQRVQVI
KDTEAGGKGTLQFGTEVVHAADGSIAALLGASPGASTAVHVMLEVITKCFPERMKEWEPKVREMIPSYGVSLMKNERLLH
DVQAATAEMLGLREGLALQLV
>Mature_500_residues
GNKQTKTDVILIGAGIMSATLGTLLKELAPEWDITVFERLEEAGVESSNEWNNAGTGHAALCELNYTVEKPDGSIDISKA
IKINEQFYVSLQFWAYLVNSGVLRDPKEFIRPLPHMSFVQGEDNVAFLKKRYETMVNNPLFKGMEFSDDPKKLAEWIPLM
MENRVVNEPIAATRIESGTDVNFGALTRKLFEHLKRKNVEIHYRHHVDDIKRTSDGLWELKVRDLDSGAVERHVAKFVFI
GAGGGSLHLLQKSGIPEGRGIGGFPVSGLFMVCNNPDVVEQHHAKVYGKAKVGAPPMSVPHLDTRFINNQKMLLFGPFAG
FSPKFLKNGSMLDLFTSVKPHNLLTMLAAGVKNMALTNYLIQQVMLSKEQRMEELREFVPTAKSEEWDVIVAGQRVQVIK
DTEAGGKGTLQFGTEVVHAADGSIAALLGASPGASTAVHVMLEVITKCFPERMKEWEPKVREMIPSYGVSLMKNERLLHD
VQAATAEMLGLREGLALQLV

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family

Homologues:

Organism=Escherichia coli, GI1788539, Length=495, Percent_Identity=53.3333333333333, Blast_Score=534, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MQO_GEOTN (A4IMR6)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001125365.1
- ProteinModelPortal:   A4IMR6
- STRING:   A4IMR6
- GeneID:   4966189
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_1250
- NMPDR:   fig|420246.5.peg.1212
- eggNOG:   COG0579
- HOGENOM:   HBG289663
- OMA:   DINYGAL
- PhylomeDB:   A4IMR6
- ProtClustDB:   PRK05257
- BioCyc:   GTHE420246:GTNG_1250-MONOMER
- HAMAP:   MF_00212
- InterPro:   IPR006231
- TIGRFAMs:   TIGR01320

Pfam domain/function: PF06039 Mqo

EC number: =1.1.5.4

Molecular weight: Translated: 55567; Mature: 55436

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNKQTKTDVILIGAGIMSATLGTLLKELAPEWDITVFERLEEAGVESSNEWNNAGTGHA
CCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCE
ALCELNYTVEKPDGSIDISKAIKINEQFYVSLQFWAYLVNSGVLRDPKEFIRPLPHMSFV
EEEEEEEEEECCCCCEEHHHEEEECCEEEEEHHHHHHHHCCCCCCCHHHHHCCCCCCEEE
QGEDNVAFLKKRYETMVNNPLFKGMEFSDDPKKLAEWIPLMMENRVVNEPIAATRIESGT
CCCCCHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCC
DVNFGALTRKLFEHLKRKNVEIHYRHHVDDIKRTSDGLWELKVRDLDSGAVERHVAKFVF
CCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCEEEEEEEECCCHHHHHHHEEEEE
IGAGGGSLHLLQKSGIPEGRGIGGFPVSGLFMVCNNPDVVEQHHAKVYGKAKVGAPPMSV
EECCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHEEECEECCCCCCCC
PHLDTRFINNQKMLLFGPFAGFSPKFLKNGSMLDLFTSVKPHNLLTMLAAGVKNMALTNY
CCCCHHEECCCEEEEEECCCCCCHHHHCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHH
LIQQVMLSKEQRMEELREFVPTAKSEEWDVIVAGQRVQVIKDTEAGGKGTLQFGTEVVHA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEECCCCCCCEEECCCCEEEC
ADGSIAALLGASPGASTAVHVMLEVITKCFPERMKEWEPKVREMIPSYGVSLMKNERLLH
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHCHHHHH
DVQAATAEMLGLREGLALQLV
HHHHHHHHHHHHHCCCEEEEC
>Mature Secondary Structure 
GNKQTKTDVILIGAGIMSATLGTLLKELAPEWDITVFERLEEAGVESSNEWNNAGTGHA
CCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCE
ALCELNYTVEKPDGSIDISKAIKINEQFYVSLQFWAYLVNSGVLRDPKEFIRPLPHMSFV
EEEEEEEEEECCCCCEEHHHEEEECCEEEEEHHHHHHHHCCCCCCCHHHHHCCCCCCEEE
QGEDNVAFLKKRYETMVNNPLFKGMEFSDDPKKLAEWIPLMMENRVVNEPIAATRIESGT
CCCCCHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCC
DVNFGALTRKLFEHLKRKNVEIHYRHHVDDIKRTSDGLWELKVRDLDSGAVERHVAKFVF
CCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCEEEEEEEECCCHHHHHHHEEEEE
IGAGGGSLHLLQKSGIPEGRGIGGFPVSGLFMVCNNPDVVEQHHAKVYGKAKVGAPPMSV
EECCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHEEECEECCCCCCCC
PHLDTRFINNQKMLLFGPFAGFSPKFLKNGSMLDLFTSVKPHNLLTMLAAGVKNMALTNY
CCCCHHEECCCEEEEEECCCCCCHHHHCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHH
LIQQVMLSKEQRMEELREFVPTAKSEEWDVIVAGQRVQVIKDTEAGGKGTLQFGTEVVHA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEECCCCCCCEEECCCCEEEC
ADGSIAALLGASPGASTAVHVMLEVITKCFPERMKEWEPKVREMIPSYGVSLMKNERLLH
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHCHHHHH
DVQAATAEMLGLREGLALQLV
HHHHHHHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA