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The map label for this gene is tkt [H]

Identifier: 138894851

GI number: 138894851

Start: 1256327

End: 1258375

Strand: Direct

Name: tkt [H]

Synonym: GTNG_1187

Alternate gene names: 138894851

Gene position: 1256327-1258375 (Clockwise)

Preceding gene: 138894850

Following gene: 138894852

Centisome position: 35.39

GC content: 55.69

Gene sequence:

>2049_bases
ATGATAGTAAATGACACCATATTGACGAAGGGGAGGAAAATGATGGCGCATTCGATTGAACAACTAGCGATTACGACGAT
TCGAACGCTGTCGATTGACGCGATCGAAAAGGCGAAATCCGGGCATCCGGGCATGCCGATGGGCGCGGCACCGATGGCGT
ACACCCTTTGGACGAAATTCATGAATCATAATCCGGCGAATCCAAACTGGTTCAACCGCGACCGGTTTGTCTTGTCAGCT
GGGCACGGGTCGATGCTGCTTTACAGCCTGCTTCATTTAAGCGGCTACGACGTATCGATGGACGACTTGAAACAGTTCCG
CCAATGGGGAAGCAAAACGCCAGGGCATCCGGAATACGGCCATACGCCGGGAGTGGAAGCGACGACCGGCCCGCTCGGCC
AAGGAATTGCGATGGCAGTCGGTATGGCGATGGCTGAGCGGCATTTGGCGGCTACATACAATCGTGACGGGTTTGACATG
ATCGACCATTATACGTACGCGATTTGCGGCGATGGTGATTTAATGGAAGGAGTGGCGAGCGAAGCTGCATCACTCGCTGG
TCATTTGCAGTTGGGCCGCTTGATCGTTCTGTATGATTCGAACGACATTTCCCTGGACGGAGAGCTTAACCTATCGTTCT
CGGAAAACGTCGCTCAACGGTTCCAAGCGTACGGTTGGCAATATTTGCGCGTCGAAGATGGCAACAACATCGAGGAAATC
GCCAAAGCGCTTGAAGAGGCGCGGGCTGACCTCAACCGGCCGACGCTCATTGAAGTGAAAACGACGATCGGCTACGGCTC
GCCGACGAAAGCAGGCACATCGAGTGTTCACGGCGCTCCGCTCGGTGCAGAAGAGGCGAAATTGACAAAAGAAGCGTATC
GCTGGACGTTTGCCGAAGATTTCTATGTGCCGGAAGAAGTGTATGCCCATTTCCGGGAAACGGTACAAGAAGTCGGGGCG
AAAAAAGAAGCCGAATGGAATGAACGATTGGCCGCTTACGAGCAGGCGTATCCAGAATTGGCCGCCCAGCTGAAGCAGGC
GATCGAAGGGAAACTTCCAGACGGTTGGGAAGCTGCGCTGCCGGTGTACGAAGCTGGAAAAAGTTTGGCGACCCGGTCGT
CGTCCGGGGAAGTCATCAACGCCATTGCCAAAGCGGTGCCGCAGTTGTTGGGCGGTTCAGCGGACTTGGCAAGCTCGAAC
AAAACGCTTATTAAAGAAGGCGGCAATTTCTTGCCGGGCAGCTATGAAGGGCGCAACATTTGGTTTGGTGTGCGCGAATT
TGCCATGGGAGCGGCGTTAAACGGCATGGCGCTCCATGGCGGGGTGAAAGTATTTGGTGGCACGTTCTTCGTGTTCTCCG
ACTATTTGCGTCCGGCGATTCGATTAGCAGCGCTCATGGGGCTGCCGGTTACCTATGTTTTGACGCATGACAGCGTTGCT
GTCGGTGAAGACGGCCCGACGCACGAGCCGATTGAACAGCTCGCTTCCTTAAGAGCGATGCCGAATTTGTCAGTCATCCG
ACCGGCTGACGCGAACGAAACGGCGGCGGCATGGCGTCTGGCGGTTGAATCGACGGACAAGCCGACCGCGCTCGTTCTGA
CGCGTCAAAACATACCGACGTTGCCGACAACGGCTGATTTGGCATATGAAGGCGTGAAAAAAGGTGCGTACGTCGTCTCG
CCGGCGAAAAACGGTGCTCCGGAGGCGCTGCTTTTGGCAACCGGTTCGGAAGTCAGCTTGGCGGTGCAAGCACAAGAAGC
GCTCGCTGCCGAAGGGATTCACGTCTCGGTCGTCAGCATGCCATCGTGGGATCGCTTTGAAGCGCAGCCAAAAGCGTACC
GTGATGAAGTGATTCCGCCGGCGGTGACGAAGCGGCTGGCCATTGAAATGGGCGCCTCGCTCGGTTGGGAGCGCTATGTT
GGTGCGGATGGCGACATTTTAGCCATCGATCGGTTTGGCGCCTCCGCTCCGGGAGAAAAAATTATGGCGGAATACGGCTT
TACCGTCGATAACGTCGTTCATCGCGTGAAAGCGTTGCTTGGCAAGTAA

Upstream 100 bases:

>100_bases
GCCAGCGCCATCGCCTCCATTAACCGGCAGTTAAGAAAGGCGAAGGCTCCTTGTTTTTTGACAGCGAAAATAACGTTGTA
CAAAGAAGTCAATTTTCTAT

Downstream 100 bases:

>100_bases
TTCAATGACCGTGAGAACAGGTTGCCCTTGTGCTGTTGCAAGGGCAACTTTTTTGCCCTATTTGCGGCCGCTGGTCACTA
TAAACAAAAATCGACAATGT

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MIVNDTILTKGRKMMAHSIEQLAITTIRTLSIDAIEKAKSGHPGMPMGAAPMAYTLWTKFMNHNPANPNWFNRDRFVLSA
GHGSMLLYSLLHLSGYDVSMDDLKQFRQWGSKTPGHPEYGHTPGVEATTGPLGQGIAMAVGMAMAERHLAATYNRDGFDM
IDHYTYAICGDGDLMEGVASEAASLAGHLQLGRLIVLYDSNDISLDGELNLSFSENVAQRFQAYGWQYLRVEDGNNIEEI
AKALEEARADLNRPTLIEVKTTIGYGSPTKAGTSSVHGAPLGAEEAKLTKEAYRWTFAEDFYVPEEVYAHFRETVQEVGA
KKEAEWNERLAAYEQAYPELAAQLKQAIEGKLPDGWEAALPVYEAGKSLATRSSSGEVINAIAKAVPQLLGGSADLASSN
KTLIKEGGNFLPGSYEGRNIWFGVREFAMGAALNGMALHGGVKVFGGTFFVFSDYLRPAIRLAALMGLPVTYVLTHDSVA
VGEDGPTHEPIEQLASLRAMPNLSVIRPADANETAAAWRLAVESTDKPTALVLTRQNIPTLPTTADLAYEGVKKGAYVVS
PAKNGAPEALLLATGSEVSLAVQAQEALAAEGIHVSVVSMPSWDRFEAQPKAYRDEVIPPAVTKRLAIEMGASLGWERYV
GADGDILAIDRFGASAPGEKIMAEYGFTVDNVVHRVKALLGK

Sequences:

>Translated_682_residues
MIVNDTILTKGRKMMAHSIEQLAITTIRTLSIDAIEKAKSGHPGMPMGAAPMAYTLWTKFMNHNPANPNWFNRDRFVLSA
GHGSMLLYSLLHLSGYDVSMDDLKQFRQWGSKTPGHPEYGHTPGVEATTGPLGQGIAMAVGMAMAERHLAATYNRDGFDM
IDHYTYAICGDGDLMEGVASEAASLAGHLQLGRLIVLYDSNDISLDGELNLSFSENVAQRFQAYGWQYLRVEDGNNIEEI
AKALEEARADLNRPTLIEVKTTIGYGSPTKAGTSSVHGAPLGAEEAKLTKEAYRWTFAEDFYVPEEVYAHFRETVQEVGA
KKEAEWNERLAAYEQAYPELAAQLKQAIEGKLPDGWEAALPVYEAGKSLATRSSSGEVINAIAKAVPQLLGGSADLASSN
KTLIKEGGNFLPGSYEGRNIWFGVREFAMGAALNGMALHGGVKVFGGTFFVFSDYLRPAIRLAALMGLPVTYVLTHDSVA
VGEDGPTHEPIEQLASLRAMPNLSVIRPADANETAAAWRLAVESTDKPTALVLTRQNIPTLPTTADLAYEGVKKGAYVVS
PAKNGAPEALLLATGSEVSLAVQAQEALAAEGIHVSVVSMPSWDRFEAQPKAYRDEVIPPAVTKRLAIEMGASLGWERYV
GADGDILAIDRFGASAPGEKIMAEYGFTVDNVVHRVKALLGK
>Mature_682_residues
MIVNDTILTKGRKMMAHSIEQLAITTIRTLSIDAIEKAKSGHPGMPMGAAPMAYTLWTKFMNHNPANPNWFNRDRFVLSA
GHGSMLLYSLLHLSGYDVSMDDLKQFRQWGSKTPGHPEYGHTPGVEATTGPLGQGIAMAVGMAMAERHLAATYNRDGFDM
IDHYTYAICGDGDLMEGVASEAASLAGHLQLGRLIVLYDSNDISLDGELNLSFSENVAQRFQAYGWQYLRVEDGNNIEEI
AKALEEARADLNRPTLIEVKTTIGYGSPTKAGTSSVHGAPLGAEEAKLTKEAYRWTFAEDFYVPEEVYAHFRETVQEVGA
KKEAEWNERLAAYEQAYPELAAQLKQAIEGKLPDGWEAALPVYEAGKSLATRSSSGEVINAIAKAVPQLLGGSADLASSN
KTLIKEGGNFLPGSYEGRNIWFGVREFAMGAALNGMALHGGVKVFGGTFFVFSDYLRPAIRLAALMGLPVTYVLTHDSVA
VGEDGPTHEPIEQLASLRAMPNLSVIRPADANETAAAWRLAVESTDKPTALVLTRQNIPTLPTTADLAYEGVKKGAYVVS
PAKNGAPEALLLATGSEVSLAVQAQEALAAEGIHVSVVSMPSWDRFEAQPKAYRDEVIPPAVTKRLAIEMGASLGWERYV
GADGDILAIDRFGASAPGEKIMAEYGFTVDNVVHRVKALLGK

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=593, Percent_Identity=26.8128161888702, Blast_Score=159, Evalue=8e-39,
Organism=Homo sapiens, GI4507521, Length=593, Percent_Identity=26.8128161888702, Blast_Score=159, Evalue=8e-39,
Organism=Homo sapiens, GI133778974, Length=588, Percent_Identity=26.1904761904762, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI225637459, Length=519, Percent_Identity=23.121387283237, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI225637463, Length=419, Percent_Identity=24.1050119331742, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI225637461, Length=419, Percent_Identity=24.1050119331742, Blast_Score=105, Evalue=2e-22,
Organism=Escherichia coli, GI48994911, Length=659, Percent_Identity=51.7450682852807, Blast_Score=673, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=660, Percent_Identity=48.3333333333333, Blast_Score=625, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17539652, Length=597, Percent_Identity=28.643216080402, Blast_Score=171, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6325331, Length=670, Percent_Identity=49.2537313432836, Blast_Score=649, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319593, Length=673, Percent_Identity=46.9539375928678, Blast_Score=603, Evalue=1e-173,
Organism=Drosophila melanogaster, GI45551847, Length=595, Percent_Identity=27.3949579831933, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI45550715, Length=595, Percent_Identity=27.3949579831933, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24666278, Length=587, Percent_Identity=27.5979557069847, Blast_Score=165, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24645119, Length=567, Percent_Identity=26.984126984127, Blast_Score=155, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 73621; Mature: 73621

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00037 MYB_1 ; PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVNDTILTKGRKMMAHSIEQLAITTIRTLSIDAIEKAKSGHPGMPMGAAPMAYTLWTKF
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
MNHNPANPNWFNRDRFVLSAGHGSMLLYSLLHLSGYDVSMDDLKQFRQWGSKTPGHPEYG
HCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCC
HTPGVEATTGPLGQGIAMAVGMAMAERHLAATYNRDGFDMIDHYTYAICGDGDLMEGVAS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCEEEEEECCCHHHHHHHH
EAASLAGHLQLGRLIVLYDSNDISLDGELNLSFSENVAQRFQAYGWQYLRVEDGNNIEEI
HHHHHHHHHEECCEEEEECCCCEEECCEEECCHHHHHHHHHHHCCEEEEEEECCCCHHHH
AKALEEARADLNRPTLIEVKTTIGYGSPTKAGTSSVHGAPLGAEEAKLTKEAYRWTFAED
HHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEECHHC
FYVPEEVYAHFRETVQEVGAKKEAEWNERLAAYEQAYPELAAQLKQAIEGKLPDGWEAAL
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCC
PVYEAGKSLATRSSSGEVINAIAKAVPQLLGGSADLASSNKTLIKEGGNFLPGSYEGRNI
CHHHCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCEE
WFGVREFAMGAALNGMALHGGVKVFGGTFFVFSDYLRPAIRLAALMGLPVTYVLTHDSVA
EEEHHHHHHHHHCCCEEEECCEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEE
VGEDGPTHEPIEQLASLRAMPNLSVIRPADANETAAAWRLAVESTDKPTALVLTRQNIPT
ECCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCHHHEEEEECCCCCCEEEEEECCCCCC
LPTTADLAYEGVKKGAYVVSPAKNGAPEALLLATGSEVSLAVQAQEALAAEGIHVSVVSM
CCCHHHHHHHHHHCCEEEECCCCCCCCCEEEEECCCCEEEEEEHHHHHHHCCCEEEEEEC
PSWDRFEAQPKAYRDEVIPPAVTKRLAIEMGASLGWERYVGADGDILAIDRFGASAPGEK
CCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEECCCCCCCCHH
IMAEYGFTVDNVVHRVKALLGK
HHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIVNDTILTKGRKMMAHSIEQLAITTIRTLSIDAIEKAKSGHPGMPMGAAPMAYTLWTKF
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
MNHNPANPNWFNRDRFVLSAGHGSMLLYSLLHLSGYDVSMDDLKQFRQWGSKTPGHPEYG
HCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCC
HTPGVEATTGPLGQGIAMAVGMAMAERHLAATYNRDGFDMIDHYTYAICGDGDLMEGVAS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCEEEEEECCCHHHHHHHH
EAASLAGHLQLGRLIVLYDSNDISLDGELNLSFSENVAQRFQAYGWQYLRVEDGNNIEEI
HHHHHHHHHEECCEEEEECCCCEEECCEEECCHHHHHHHHHHHCCEEEEEEECCCCHHHH
AKALEEARADLNRPTLIEVKTTIGYGSPTKAGTSSVHGAPLGAEEAKLTKEAYRWTFAED
HHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEECHHC
FYVPEEVYAHFRETVQEVGAKKEAEWNERLAAYEQAYPELAAQLKQAIEGKLPDGWEAAL
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCC
PVYEAGKSLATRSSSGEVINAIAKAVPQLLGGSADLASSNKTLIKEGGNFLPGSYEGRNI
CHHHCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCEE
WFGVREFAMGAALNGMALHGGVKVFGGTFFVFSDYLRPAIRLAALMGLPVTYVLTHDSVA
EEEHHHHHHHHHCCCEEEECCEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEE
VGEDGPTHEPIEQLASLRAMPNLSVIRPADANETAAAWRLAVESTDKPTALVLTRQNIPT
ECCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCHHHEEEEECCCCCCEEEEEECCCCCC
LPTTADLAYEGVKKGAYVVSPAKNGAPEALLLATGSEVSLAVQAQEALAAEGIHVSVVSM
CCCHHHHHHHHHHCCEEEECCCCCCCCCEEEEECCCCEEEEEEHHHHHHHCCCEEEEEEC
PSWDRFEAQPKAYRDEVIPPAVTKRLAIEMGASLGWERYVGADGDILAIDRFGASAPGEK
CCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEECCCCCCCCHH
IMAEYGFTVDNVVHRVKALLGK
HHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]