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The map label for this gene is fabF [H]

Identifier: 138894357

GI number: 138894357

Start: 764971

End: 766209

Strand: Direct

Name: fabF [H]

Synonym: GTNG_0685

Alternate gene names: 138894357

Gene position: 764971-766209 (Clockwise)

Preceding gene: 138894356

Following gene: 138894358

Centisome position: 21.55

GC content: 53.75

Gene sequence:

>1239_bases
ATGGAAAAAAGACGAGTTGTCGTGACCGGGATGGGGGCTGTCACCCCACTCGGCAATGACGTCGAAACAACATGGAAAAA
CATCATTGCCGGTCAGTCTGGCATCGATATTGTCACTCGTGTCAATCCCGACGATTTTCCAGCGAAAGTGGCGGCGGAAG
TCAAAGATTTTGACCCGACGGTGTTTATGGATCGCCGCGAGGCACGGAAGATGGATCGTTTTACACAATACGCCGTGGCC
GCAGCGCTTATGGCGGTGAAAGACGCCAATCTGGAAATCAATGAACAAAACGCTGAACGAGTCGGTGTCTGGATCGGATC
TGGTATCGGCGGGATGGAGACGTTTGAGCAACAGTTTGAAACTTTCCAGAAACGCGGCTACCGTCGGGTGAGCCCGTTTT
TCGTGCCGATGATGATTCCGGATATGGCGGCTGGACAAGTGTCGATCATTCTCGGGGCAAAGGGAATCAATTCGTGCACA
GTCACTGCTTGCGCGACTGGAGCCAATTCGATCGGCGACGCGTTTAAAGTCATTCAGCGCGGTGATGCCGACGTGATGAT
CACTGGCGGAGCCGAAGCGCCGATTACGACAATGTCGTTTGCCGGCTTTTGTGCGAACACAGCGCTCTCGACGAATCCAG
ATCCGAAAACGGCAAGCCGCCCGTTTGATAAAAACCGTGACGGATTTGTCATGGGCGAAGGAGCAGGCATCATCGTTCTT
GAAGAGTTGGAGCACGCGTTGCGTCGCGGAGCGCCGATTTATGCCGAAATTGTTGGCTACGGCGCCACCGGAGATGCTTA
CCATATTACGGCGCCGGCGCCGGGCGGTGAAGGGGGCGTGCGGGCGATGCGCCAAGCGCTCCATGACGCTGGCTTGCAGC
CGGAGGAGATCGACTATATTAATGCCCACGGCACAAGCACAGAGTACAATGATAAGTATGAGACGTTTGCCATTAAAGAA
GTGTTCGGTGATCATGCGTATAAGCTCGCCGTCAGCTCAACGAAGTCGATGACCGGCCACTTGCTTGGGGCGACCGGTGC
GGTGGAAGCTATTTTCTCGGTGTTGACGATTCGCGATGGTATCATTCCGCCGACGATCAACTACGAAACGCCAGATCCGG
AATGCGATCTTGACTATGTGCCGAATGAAGCACGCAAGCAAGAAGTGCGCGCAGTCTTAAGCAACTCATTTGGATTTGGC
GGCCATAACGCGACATTGATTTTCAAAAAATATGTGTGA

Upstream 100 bases:

>100_bases
GTCATGGTTGGATTCGGCGGCGGGCTGACGTGGGGTGCGATCGCCTTGCGCTGGGGCCGCTAACAACTTTTAGATTATCG
GAAAAAGGAGAGACGAAGCG

Downstream 100 bases:

>100_bases
CGAACGGAAATGAGAGCCTTCGGTTGAACGAAGCTGCCCCCGTTAGGCATAACTAACGAGCGGCAGTTCGTTCAAAGCGA
GGCTCTTTTTTGATTGGCGC

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MEKRRVVVTGMGAVTPLGNDVETTWKNIIAGQSGIDIVTRVNPDDFPAKVAAEVKDFDPTVFMDRREARKMDRFTQYAVA
AALMAVKDANLEINEQNAERVGVWIGSGIGGMETFEQQFETFQKRGYRRVSPFFVPMMIPDMAAGQVSIILGAKGINSCT
VTACATGANSIGDAFKVIQRGDADVMITGGAEAPITTMSFAGFCANTALSTNPDPKTASRPFDKNRDGFVMGEGAGIIVL
EELEHALRRGAPIYAEIVGYGATGDAYHITAPAPGGEGGVRAMRQALHDAGLQPEEIDYINAHGTSTEYNDKYETFAIKE
VFGDHAYKLAVSSTKSMTGHLLGATGAVEAIFSVLTIRDGIIPPTINYETPDPECDLDYVPNEARKQEVRAVLSNSFGFG
GHNATLIFKKYV

Sequences:

>Translated_412_residues
MEKRRVVVTGMGAVTPLGNDVETTWKNIIAGQSGIDIVTRVNPDDFPAKVAAEVKDFDPTVFMDRREARKMDRFTQYAVA
AALMAVKDANLEINEQNAERVGVWIGSGIGGMETFEQQFETFQKRGYRRVSPFFVPMMIPDMAAGQVSIILGAKGINSCT
VTACATGANSIGDAFKVIQRGDADVMITGGAEAPITTMSFAGFCANTALSTNPDPKTASRPFDKNRDGFVMGEGAGIIVL
EELEHALRRGAPIYAEIVGYGATGDAYHITAPAPGGEGGVRAMRQALHDAGLQPEEIDYINAHGTSTEYNDKYETFAIKE
VFGDHAYKLAVSSTKSMTGHLLGATGAVEAIFSVLTIRDGIIPPTINYETPDPECDLDYVPNEARKQEVRAVLSNSFGFG
GHNATLIFKKYV
>Mature_412_residues
MEKRRVVVTGMGAVTPLGNDVETTWKNIIAGQSGIDIVTRVNPDDFPAKVAAEVKDFDPTVFMDRREARKMDRFTQYAVA
AALMAVKDANLEINEQNAERVGVWIGSGIGGMETFEQQFETFQKRGYRRVSPFFVPMMIPDMAAGQVSIILGAKGINSCT
VTACATGANSIGDAFKVIQRGDADVMITGGAEAPITTMSFAGFCANTALSTNPDPKTASRPFDKNRDGFVMGEGAGIIVL
EELEHALRRGAPIYAEIVGYGATGDAYHITAPAPGGEGGVRAMRQALHDAGLQPEEIDYINAHGTSTEYNDKYETFAIKE
VFGDHAYKLAVSSTKSMTGHLLGATGAVEAIFSVLTIRDGIIPPTINYETPDPECDLDYVPNEARKQEVRAVLSNSFGFG
GHNATLIFKKYV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=415, Percent_Identity=51.3253012048193, Blast_Score=394, Evalue=1e-110,
Organism=Homo sapiens, GI223972627, Length=169, Percent_Identity=56.8047337278106, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI41872631, Length=429, Percent_Identity=26.3403263403263, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1787337, Length=412, Percent_Identity=52.9126213592233, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1788663, Length=416, Percent_Identity=41.1057692307692, Blast_Score=273, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71983541, Length=414, Percent_Identity=37.1980676328502, Blast_Score=257, Evalue=9e-69,
Organism=Caenorhabditis elegans, GI71983535, Length=257, Percent_Identity=42.8015564202335, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI212642053, Length=430, Percent_Identity=26.7441860465116, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=413, Percent_Identity=24.455205811138, Blast_Score=102, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320904, Length=448, Percent_Identity=37.9464285714286, Blast_Score=290, Evalue=3e-79,
Organism=Drosophila melanogaster, GI24644341, Length=420, Percent_Identity=46.9047619047619, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI221330659, Length=428, Percent_Identity=26.6355140186916, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI19920632, Length=428, Percent_Identity=26.6355140186916, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24581345, Length=427, Percent_Identity=24.3559718969555, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44356; Mature: 44356

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRRVVVTGMGAVTPLGNDVETTWKNIIAGQSGIDIVTRVNPDDFPAKVAAEVKDFDPT
CCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCCC
VFMDRREARKMDRFTQYAVAAALMAVKDANLEINEQNAERVGVWIGSGIGGMETFEQQFE
EEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEECCCCHHHHHHHHHH
TFQKRGYRRVSPFFVPMMIPDMAAGQVSIILGAKGINSCTVTACATGANSIGDAFKVIQR
HHHHCCCEECCCEEEEEECCCCCCCEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHC
GDADVMITGGAEAPITTMSFAGFCANTALSTNPDPKTASRPFDKNRDGFVMGEGAGIIVL
CCCCEEEECCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
EELEHALRRGAPIYAEIVGYGATGDAYHITAPAPGGEGGVRAMRQALHDAGLQPEEIDYI
HHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEE
NAHGTSTEYNDKYETFAIKEVFGDHAYKLAVSSTKSMTGHLLGATGAVEAIFSVLTIRDG
ECCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHCC
IIPPTINYETPDPECDLDYVPNEARKQEVRAVLSNSFGFGGHNATLIFKKYV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MEKRRVVVTGMGAVTPLGNDVETTWKNIIAGQSGIDIVTRVNPDDFPAKVAAEVKDFDPT
CCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCCC
VFMDRREARKMDRFTQYAVAAALMAVKDANLEINEQNAERVGVWIGSGIGGMETFEQQFE
EEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEECCCCHHHHHHHHHH
TFQKRGYRRVSPFFVPMMIPDMAAGQVSIILGAKGINSCTVTACATGANSIGDAFKVIQR
HHHHCCCEECCCEEEEEECCCCCCCEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHC
GDADVMITGGAEAPITTMSFAGFCANTALSTNPDPKTASRPFDKNRDGFVMGEGAGIIVL
CCCCEEEECCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
EELEHALRRGAPIYAEIVGYGATGDAYHITAPAPGGEGGVRAMRQALHDAGLQPEEIDYI
HHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEE
NAHGTSTEYNDKYETFAIKEVFGDHAYKLAVSSTKSMTGHLLGATGAVEAIFSVLTIRDG
ECCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHCC
IIPPTINYETPDPECDLDYVPNEARKQEVRAVLSNSFGFGGHNATLIFKKYV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]