Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 138894356

GI number: 138894356

Start: 763992

End: 764933

Strand: Direct

Name: fabH [H]

Synonym: GTNG_0684

Alternate gene names: 138894356

Gene position: 763992-764933 (Clockwise)

Preceding gene: 138894354

Following gene: 138894357

Centisome position: 21.52

GC content: 51.7

Gene sequence:

>942_bases
ATGAGTAGCATGGGAGCAGGAATTATCGGCGTTGGTTACTATGCACCGGAAAAGGTGTTGACAAACGCTGACTTGGAAAA
AATGATGGACACATCAGATGAATGGATTCGAACGCGCACGGGGATTGAAGAACGGCGCATCGCTCCAGATGAGATGGATA
CATCTGACATGGCGTATTTTGCTGCTGAGAAGGCGCTCGCTCACGCGGGCATTTCCGCGAAAGACATTGATTTGATTTTG
GTAGCTACCGTTACTCCGGACCGCCCGTTCCCGTCTGTTGCGTGCATGTTGCAAGAGCGCCTCGGTGCTGTCAACGCTGC
AGCGTTGGACATTAGCGCTGCCTGCGCCGGGTTTATGTATGGGGTCGTGACGGCGAGCCAATTCATTGACAATGGTGCAT
ACAAGTATATATTGGTAGTAGGCGCGGAAAAACTATCAAAAATTATTGATTGGACCGACCGGAATACGGCAGTGCTGTTT
GGCGATGGCGCCGGGGCGGTCGTCATGGGGCCGGTGTCACCCGGACGCGGCATTTTATCCTTTGAATTAGGCGCTGACGG
AACGGGAGGAAAACATTTATATCAAGACGAATATATCATCATGAACGGCCGTGAAGTGTTTAAGTTCGCTGTCCGGCAAA
TGGGAGAGTCAAGCTTGAATGTGCTCGAAAAAGCTGGCCTATCGAAAAATGATGTTGACTTTCTGATTCCCCACCAGGCG
AACATTCGCATTATGGAGGCAGCCAGACAGAGGCTCGAGCTGCCGGAAGAGAAAATGTCAACAACGATTCGCCGATACGG
CAATACGTCAGCCGCGTCCATTCCAATTTCACTCGCTGAGGAATTTGAAGCGGGGAAAATTAAAGATGATGATGTCATCG
TCATGGTTGGATTCGGCGGCGGGCTGACGTGGGGTGCGATCGCCTTGCGCTGGGGCCGCTAA

Upstream 100 bases:

>100_bases
TTAGTACCAAGTAATAATAATTGGTTATGTGGATTGATTGTATATTGGGAATTACGCTGTATTCAAAAGGATTTTCGGTT
ATTTTGCAAGGAAAAAGGAG

Downstream 100 bases:

>100_bases
CAACTTTTAGATTATCGGAAAAAGGAGAGACGAAGCGATGGAAAAAAGACGAGTTGTCGTGACCGGGATGGGGGCTGTCA
CCCCACTCGGCAATGACGTC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSSMGAGIIGVGYYAPEKVLTNADLEKMMDTSDEWIRTRTGIEERRIAPDEMDTSDMAYFAAEKALAHAGISAKDIDLIL
VATVTPDRPFPSVACMLQERLGAVNAAALDISAACAGFMYGVVTASQFIDNGAYKYILVVGAEKLSKIIDWTDRNTAVLF
GDGAGAVVMGPVSPGRGILSFELGADGTGGKHLYQDEYIIMNGREVFKFAVRQMGESSLNVLEKAGLSKNDVDFLIPHQA
NIRIMEAARQRLELPEEKMSTTIRRYGNTSAASIPISLAEEFEAGKIKDDDVIVMVGFGGGLTWGAIALRWGR

Sequences:

>Translated_313_residues
MSSMGAGIIGVGYYAPEKVLTNADLEKMMDTSDEWIRTRTGIEERRIAPDEMDTSDMAYFAAEKALAHAGISAKDIDLIL
VATVTPDRPFPSVACMLQERLGAVNAAALDISAACAGFMYGVVTASQFIDNGAYKYILVVGAEKLSKIIDWTDRNTAVLF
GDGAGAVVMGPVSPGRGILSFELGADGTGGKHLYQDEYIIMNGREVFKFAVRQMGESSLNVLEKAGLSKNDVDFLIPHQA
NIRIMEAARQRLELPEEKMSTTIRRYGNTSAASIPISLAEEFEAGKIKDDDVIVMVGFGGGLTWGAIALRWGR
>Mature_312_residues
SSMGAGIIGVGYYAPEKVLTNADLEKMMDTSDEWIRTRTGIEERRIAPDEMDTSDMAYFAAEKALAHAGISAKDIDLILV
ATVTPDRPFPSVACMLQERLGAVNAAALDISAACAGFMYGVVTASQFIDNGAYKYILVVGAEKLSKIIDWTDRNTAVLFG
DGAGAVVMGPVSPGRGILSFELGADGTGGKHLYQDEYIIMNGREVFKFAVRQMGESSLNVLEKAGLSKNDVDFLIPHQAN
IRIMEAARQRLELPEEKMSTTIRRYGNTSAASIPISLAEEFEAGKIKDDDVIVMVGFGGGLTWGAIALRWGR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=318, Percent_Identity=44.6540880503145, Blast_Score=267, Evalue=6e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 33774; Mature: 33643

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSMGAGIIGVGYYAPEKVLTNADLEKMMDTSDEWIRTRTGIEERRIAPDEMDTSDMAYF
CCCCCCCEEEECCCCCHHHHCCCHHHHHHCCCHHHHHHHCCCHHHCCCCCCCCCHHHHHH
AAEKALAHAGISAKDIDLILVATVTPDRPFPSVACMLQERLGAVNAAALDISAACAGFMY
HHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GVVTASQFIDNGAYKYILVVGAEKLSKIIDWTDRNTAVLFGDGAGAVVMGPVSPGRGILS
HHHHHHHHHCCCCEEEEEEECHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCCEEE
FELGADGTGGKHLYQDEYIIMNGREVFKFAVRQMGESSLNVLEKAGLSKNDVDFLIPHQA
EECCCCCCCCCCEECCCEEEECCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCEEEECCCC
NIRIMEAARQRLELPEEKMSTTIRRYGNTSAASIPISLAEEFEAGKIKDDDVIVMVGFGG
CEEHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEECHHHHHCCCCCCCCCCCEEEEEECCC
GLTWGAIALRWGR
CCCEEHEEEECCC
>Mature Secondary Structure 
SSMGAGIIGVGYYAPEKVLTNADLEKMMDTSDEWIRTRTGIEERRIAPDEMDTSDMAYF
CCCCCCEEEECCCCCHHHHCCCHHHHHHCCCHHHHHHHCCCHHHCCCCCCCCCHHHHHH
AAEKALAHAGISAKDIDLILVATVTPDRPFPSVACMLQERLGAVNAAALDISAACAGFMY
HHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GVVTASQFIDNGAYKYILVVGAEKLSKIIDWTDRNTAVLFGDGAGAVVMGPVSPGRGILS
HHHHHHHHHCCCCEEEEEEECHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCCEEE
FELGADGTGGKHLYQDEYIIMNGREVFKFAVRQMGESSLNVLEKAGLSKNDVDFLIPHQA
EECCCCCCCCCCEECCCEEEECCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCEEEECCCC
NIRIMEAARQRLELPEEKMSTTIRRYGNTSAASIPISLAEEFEAGKIKDDDVIVMVGFGG
CEEHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEECHHHHHCCCCCCCCCCCEEEEEECCC
GLTWGAIALRWGR
CCCEEHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA