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The map label for this gene is argC

Identifier: 138894342

GI number: 138894342

Start: 746796

End: 747830

Strand: Direct

Name: argC

Synonym: GTNG_0670

Alternate gene names: 138894342

Gene position: 746796-747830 (Clockwise)

Preceding gene: 138894341

Following gene: 138894343

Centisome position: 21.03

GC content: 52.46

Gene sequence:

>1035_bases
ATGAAGGTGGCGATTATTGGGGCGACAGGATACAGCGGTGCAGAGCTGTTCCGCCTGTTGCAAGCTCACCCGCACGTTGA
TCGCTGTGACGTCTACTTGTCGTCACAAGATGGGGTGCATTTATCGGAAAGCTTCCCGCACGTCGGGGCGGTTGACGGGG
CGGTATTGCATAAACTTGATATCGAAGCGCTTGCCAAGTATGACGCGGTTTTTTTCGCTACGCCGCCCGGAGTATCGGGA
GAGTGGGCGCCAGCGCTTGTTGACCGCGGAGTGAAAGTGATTGATTTGTCGGGAGATTTTCGCTTGAAGGATGGAGCGGT
ATACGAGCGATGGTACGGGCGTGAGGCGGCGCCGGCTGCGTATTTAAAGCGGGCGGTGTACGGATTGACAGAGTGGAACC
GGGATGCGGTGCGCGAGGCCGAGCTTCTATCGAATCCAGGCTGTTATCCGACGGCGACGTTGCTTGGTTTAGCACCGCTT
GTAAAAGAAAGACTCATTGAAGAGGACTCGATTATCGTTGACGCCAAGTCGGGTGTATCCGGTGCGGGGCGAAAAGCCGG
GCTTGGGACGCATTTTTCGGAAGTAAACGAAAACGTGAAAATTTATAAAGTGAATGCCCACCAACATATTCCAGAAATTG
AGCAAATGCTTGGAACGTGGAACGGAGCGATGAAGCCGATTACGTTCAGCACCCACTTGATTCCAATGACAAGGGGCATT
ATGTCGACGATATACGCGAAGGTGAAGCAGCCGTTTTCGCTGAACGACTTAATAGATTTATATAAAACAAGTTATGAAGA
TGCATCGTTTGTCCGCATTCGCCAGCCAGGACAGTTCCCGGCGACGAAAGAAGTGTACGGCTCCAACTATTGCGATATTG
GCCTCGCTTATGATGAGCGGACAGGACGGGTGACGGTCGTGTCAGTGATCGATAACTTAATGAAAGGCGCTGCTGGGCAG
GCAGTGCAAAATTTCAATCTGATGATGGGATGGGATGAGGTCGAGGGCCTATGCTTCCTGCCGACTTATCCGTGA

Upstream 100 bases:

>100_bases
GAGAGAAAAAATCTTCAAAAATTATTAAATATACATTTGATTTTATTTTTATGCAGTATTATAATGAGAACTACATGAAG
CATATAGGTAGGTGGACGGG

Downstream 100 bases:

>100_bases
GCGTGAGGGAAGGGGGAACGAAACGATGACGGTAACGAAACAAACGGCGCAAGTGACGGCGCTTGCTGGTGGAACGGTCG
TCACGCCGAAAGGGTTTCAG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKVAIIGATGYSGAELFRLLQAHPHVDRCDVYLSSQDGVHLSESFPHVGAVDGAVLHKLDIEALAKYDAVFFATPPGVSG
EWAPALVDRGVKVIDLSGDFRLKDGAVYERWYGREAAPAAYLKRAVYGLTEWNRDAVREAELLSNPGCYPTATLLGLAPL
VKERLIEEDSIIVDAKSGVSGAGRKAGLGTHFSEVNENVKIYKVNAHQHIPEIEQMLGTWNGAMKPITFSTHLIPMTRGI
MSTIYAKVKQPFSLNDLIDLYKTSYEDASFVRIRQPGQFPATKEVYGSNYCDIGLAYDERTGRVTVVSVIDNLMKGAAGQ
AVQNFNLMMGWDEVEGLCFLPTYP

Sequences:

>Translated_344_residues
MKVAIIGATGYSGAELFRLLQAHPHVDRCDVYLSSQDGVHLSESFPHVGAVDGAVLHKLDIEALAKYDAVFFATPPGVSG
EWAPALVDRGVKVIDLSGDFRLKDGAVYERWYGREAAPAAYLKRAVYGLTEWNRDAVREAELLSNPGCYPTATLLGLAPL
VKERLIEEDSIIVDAKSGVSGAGRKAGLGTHFSEVNENVKIYKVNAHQHIPEIEQMLGTWNGAMKPITFSTHLIPMTRGI
MSTIYAKVKQPFSLNDLIDLYKTSYEDASFVRIRQPGQFPATKEVYGSNYCDIGLAYDERTGRVTVVSVIDNLMKGAAGQ
AVQNFNLMMGWDEVEGLCFLPTYP
>Mature_344_residues
MKVAIIGATGYSGAELFRLLQAHPHVDRCDVYLSSQDGVHLSESFPHVGAVDGAVLHKLDIEALAKYDAVFFATPPGVSG
EWAPALVDRGVKVIDLSGDFRLKDGAVYERWYGREAAPAAYLKRAVYGLTEWNRDAVREAELLSNPGCYPTATLLGLAPL
VKERLIEEDSIIVDAKSGVSGAGRKAGLGTHFSEVNENVKIYKVNAHQHIPEIEQMLGTWNGAMKPITFSTHLIPMTRGI
MSTIYAKVKQPFSLNDLIDLYKTSYEDASFVRIRQPGQFPATKEVYGSNYCDIGLAYDERTGRVTVVSVIDNLMKGAAGQ
AVQNFNLMMGWDEVEGLCFLPTYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=343, Percent_Identity=37.3177842565598, Blast_Score=205, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6320913, Length=344, Percent_Identity=30.5232558139535, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_GEOTN (A4IL46)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001124795.1
- ProteinModelPortal:   A4IL46
- SMR:   A4IL46
- STRING:   A4IL46
- GeneID:   4965613
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_0670
- NMPDR:   fig|420246.5.peg.650
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   GCFPTAS
- PhylomeDB:   A4IL46
- ProtClustDB:   PRK00436
- BioCyc:   GTHE420246:GTNG_0670-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37749; Mature: 37749

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 148-148

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAIIGATGYSGAELFRLLQAHPHVDRCDVYLSSQDGVHLSESFPHVGAVDGAVLHKLD
CEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEHHCCCCCCCCCCCHHHHHHH
IEALAKYDAVFFATPPGVSGEWAPALVDRGVKVIDLSGDFRLKDGAVYERWYGREAAPAA
HHHHHHHCEEEEECCCCCCCCCCHHHHHCCCEEEECCCCEEECCCCHHHHHCCCCCCHHH
YLKRAVYGLTEWNRDAVREAELLSNPGCYPTATLLGLAPLVKERLIEEDSIIVDAKSGVS
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
GAGRKAGLGTHFSEVNENVKIYKVNAHQHIPEIEQMLGTWNGAMKPITFSTHLIPMTRGI
CCCCCCCCCCCHHHHCCCEEEEEECCHHCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHHH
MSTIYAKVKQPFSLNDLIDLYKTSYEDASFVRIRQPGQFPATKEVYGSNYCDIGLAYDER
HHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHCCCCEEEEEEEECC
TGRVTVVSVIDNLMKGAAGQAVQNFNLMMGWDEVEGLCFLPTYP
CCCEEHHHHHHHHHHCCCCHHHHCCEEEECHHHHCCEEEECCCC
>Mature Secondary Structure
MKVAIIGATGYSGAELFRLLQAHPHVDRCDVYLSSQDGVHLSESFPHVGAVDGAVLHKLD
CEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEHHCCCCCCCCCCCHHHHHHH
IEALAKYDAVFFATPPGVSGEWAPALVDRGVKVIDLSGDFRLKDGAVYERWYGREAAPAA
HHHHHHHCEEEEECCCCCCCCCCHHHHHCCCEEEECCCCEEECCCCHHHHHCCCCCCHHH
YLKRAVYGLTEWNRDAVREAELLSNPGCYPTATLLGLAPLVKERLIEEDSIIVDAKSGVS
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
GAGRKAGLGTHFSEVNENVKIYKVNAHQHIPEIEQMLGTWNGAMKPITFSTHLIPMTRGI
CCCCCCCCCCCHHHHCCCEEEEEECCHHCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHHH
MSTIYAKVKQPFSLNDLIDLYKTSYEDASFVRIRQPGQFPATKEVYGSNYCDIGLAYDER
HHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHCCCCEEEEEEEECC
TGRVTVVSVIDNLMKGAAGQAVQNFNLMMGWDEVEGLCFLPTYP
CCCEEHHHHHHHHHHCCCCHHHHCCEEEECHHHHCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA