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The map label for this gene is moaE [H]

Identifier: 138894336

GI number: 138894336

Start: 742865

End: 743332

Strand: Direct

Name: moaE [H]

Synonym: GTNG_0664

Alternate gene names: 138894336

Gene position: 742865-743332 (Clockwise)

Preceding gene: 138894335

Following gene: 138894337

Centisome position: 20.92

GC content: 53.21

Gene sequence:

>468_bases
ATGACCGAATCGTTATTTTCCATCACGTCCGAGCCGATTTCGGTCGAGGCTGTGATGAAAAAAGTGATGCGTCCGGAAGC
GGGAGCTGTTGCTGTGTTTGCCGGCACGGTGCGCGAATGGACGAACGGCAAGCGGACGCTCTTTTTACAATACGAAGCGT
ACGTGTCGATGGCAGAGAAAATGCTGGCGCAAATCGGGGCGGAAATTGCGGAAAAATGGCCGGGAACGAAAACAGCGATT
ACCCACCGGATCGGACGCCTCGAAATCGGCGACATCGCCGTCGTCATCGCGGTTTCCTCGCCGCATCGTGCGGAAGCGTA
TGAAGCGAACCGCTACGCTATCGAACGGATCAAACAAATTGTGCCGATTTGGAAAAAAGAACAATGGGAAGATGGCAGCG
CATGGATTGGCGATCAACTGGAAACAAAAGCATATCCGTCCGGAAAACCGGAGGTGAATGAACCATGA

Upstream 100 bases:

>100_bases
CTTGGGAACCGCTCTCTCGACCGTTGCCGCACCCGGTGTTTTCGATGGCTGATGATGCCCGATATATCCCATGGTTAATG
AATGAGGTGAGAATGCGGAC

Downstream 100 bases:

>100_bases
TCCGTCTCTTGTTTTTTGCCCATTTGGGTGAACAAGTTGGCGAGCGGCAAGTAACATGGCCGCACGTCCCAGAAACGGTA
GGGAAGCTGAAAGAAGAAGT

Product: molybdopterin converting factor subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MTESLFSITSEPISVEAVMKKVMRPEAGAVAVFAGTVREWTNGKRTLFLQYEAYVSMAEKMLAQIGAEIAEKWPGTKTAI
THRIGRLEIGDIAVVIAVSSPHRAEAYEANRYAIERIKQIVPIWKKEQWEDGSAWIGDQLETKAYPSGKPEVNEP

Sequences:

>Translated_155_residues
MTESLFSITSEPISVEAVMKKVMRPEAGAVAVFAGTVREWTNGKRTLFLQYEAYVSMAEKMLAQIGAEIAEKWPGTKTAI
THRIGRLEIGDIAVVIAVSSPHRAEAYEANRYAIERIKQIVPIWKKEQWEDGSAWIGDQLETKAYPSGKPEVNEP
>Mature_154_residues
TESLFSITSEPISVEAVMKKVMRPEAGAVAVFAGTVREWTNGKRTLFLQYEAYVSMAEKMLAQIGAEIAEKWPGTKTAIT
HRIGRLEIGDIAVVIAVSSPHRAEAYEANRYAIERIKQIVPIWKKEQWEDGSAWIGDQLETKAYPSGKPEVNEP

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=138, Percent_Identity=41.304347826087, Blast_Score=123, Evalue=5e-29,
Organism=Escherichia coli, GI1787003, Length=137, Percent_Identity=36.4963503649635, Blast_Score=87, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17509279, Length=126, Percent_Identity=38.0952380952381, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356259, Length=131, Percent_Identity=40.4580152671756, Blast_Score=103, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17293; Mature: 17162

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESLFSITSEPISVEAVMKKVMRPEAGAVAVFAGTVREWTNGKRTLFLQYEAYVSMAEK
CCCCHHHHCCCCEEHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCEEEEEEHHHHHHHHHH
MLAQIGAEIAEKWPGTKTAITHRIGRLEIGDIAVVIAVSSPHRAEAYEANRYAIERIKQI
HHHHHHHHHHHHCCCCHHHHHHHHCCEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
VPIWKKEQWEDGSAWIGDQLETKAYPSGKPEVNEP
HCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TESLFSITSEPISVEAVMKKVMRPEAGAVAVFAGTVREWTNGKRTLFLQYEAYVSMAEK
CCCHHHHCCCCEEHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCEEEEEEHHHHHHHHHH
MLAQIGAEIAEKWPGTKTAITHRIGRLEIGDIAVVIAVSSPHRAEAYEANRYAIERIKQI
HHHHHHHHHHHHCCCCHHHHHHHHCCEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
VPIWKKEQWEDGSAWIGDQLETKAYPSGKPEVNEP
HCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]