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The map label for this gene is sbcD [H]

Identifier: 138894264

GI number: 138894264

Start: 656734

End: 657912

Strand: Direct

Name: sbcD [H]

Synonym: GTNG_0590

Alternate gene names: 138894264

Gene position: 656734-657912 (Clockwise)

Preceding gene: 138894263

Following gene: 138894265

Centisome position: 18.5

GC content: 56.57

Gene sequence:

>1179_bases
ATGCGCATTTTGCATACGGCGGACTGGCATCTCGGGCGAACACTCGAGGGTCGAAGCCGGTTGGCTGAGCAGGAGGCGTT
TATCGATGAGCTCATCGAAATTGTCGAGAAAGAACAAATTGACGCCATTTTAATGGCCGGTGATGTATTTGATTCCGTCA
ATCCGCCGGCGGCGGCGGAACAATTGTTTTACGAAAGTTTAGCCCGCCTGTCCGACAAGGGACGGCGGCCAGTCGCCGTC
ATCAGTGGAAATCATGACCATCCGGACCGCATCAGCGCCGCCCGGACGTTGCTTTCCGATTATCATATTTTTCTGTTCGG
CCGTCCGGAAGCTTCCGTTTGCCGAATTGATGTCCCCTCATGCGGGGAGACGATGATGCTTGCTCCGTTGGCCTATCCGT
CCGAATCGCGCCTTGCTGAGCTGCTGTCGTCTGATCATCGGGAAGCGGTGCTTCGTGACCGTTATGATGACCGCATCCGT
GCACTGTTAGAGATGATGGCCGCTTCATTCACTGAAAAGACGGTCAATATAGTGATGAGCCATCTTTATGTCGCCGGCGG
CCGTACGTCCGATTCTGAGCGGCCGATTGAAGTAGGTGGCGCCTATACAGTGGCGGCGACGAGTTTGCCGAAAGCCGCCC
AATATGTGGCGCTCGGTCATCTACACCGGCCGCAGGACGTCAAACGGGCGGAGACGGCAGCACGCTATTCCGGTTCACCG
CTCGCTTATAGCTTTTCCGAAGCTGGGCATGCCAAATCGGTCACGGTCGTTGATGTGCACCCGGGCGGGGCGGCTAGCGT
GACGGAAATTCCGCTTGCCGCCGGCAAGCCGCTCGTCCGTTGGAAGGCGACAGAAGGGCTCGCCCAAGTGTACCGTTGGT
GCGAGGAAGGAAAAGACCAGTCGTGCTGGGTTGATTTGGAGCTCCATGTGACTGAGCCGTTAACAATGGAAGAAATTTAC
CGGTTGCGCAAGCTTCATCCAGGTTTTGTTTATATCCGTCCGGTGTTTCCCCAACGGGTGGAAGAAGAGGCTGAAGTGAG
CCGCGAGGCGCTCTCGCTTGAAGAGATGTTCTGCCGTTTTTACAAACGGCAAACAGGGGGACAGACGCCGGATGAAGAGC
TCGTCCGCCTTTTTTTAGAGCTGGCGGCGGAAGAAGAGCAGGAGGGGGGAGAGGAGTGA

Upstream 100 bases:

>100_bases
CCATTGAACAAATTTGGCGCGTGCCGGTGGCGGAATGTTACTTATATTCGTTTGACGGTGAATATTTTCTTGCAGTGGAG
TGAAGCGGAGGGGGAGAGAC

Downstream 100 bases:

>100_bases
AGCCGATTTCACTGACGATTGCCGGGCTTCATAGTTTCCGCGAAAAACAGACGATCGATTTCACTGTGCTGTGCGATGGT
GGCGTGTTTGGTATTTTCGG

Product: exonuclease SbcD-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MRILHTADWHLGRTLEGRSRLAEQEAFIDELIEIVEKEQIDAILMAGDVFDSVNPPAAAEQLFYESLARLSDKGRRPVAV
ISGNHDHPDRISAARTLLSDYHIFLFGRPEASVCRIDVPSCGETMMLAPLAYPSESRLAELLSSDHREAVLRDRYDDRIR
ALLEMMAASFTEKTVNIVMSHLYVAGGRTSDSERPIEVGGAYTVAATSLPKAAQYVALGHLHRPQDVKRAETAARYSGSP
LAYSFSEAGHAKSVTVVDVHPGGAASVTEIPLAAGKPLVRWKATEGLAQVYRWCEEGKDQSCWVDLELHVTEPLTMEEIY
RLRKLHPGFVYIRPVFPQRVEEEAEVSREALSLEEMFCRFYKRQTGGQTPDEELVRLFLELAAEEEQEGGEE

Sequences:

>Translated_392_residues
MRILHTADWHLGRTLEGRSRLAEQEAFIDELIEIVEKEQIDAILMAGDVFDSVNPPAAAEQLFYESLARLSDKGRRPVAV
ISGNHDHPDRISAARTLLSDYHIFLFGRPEASVCRIDVPSCGETMMLAPLAYPSESRLAELLSSDHREAVLRDRYDDRIR
ALLEMMAASFTEKTVNIVMSHLYVAGGRTSDSERPIEVGGAYTVAATSLPKAAQYVALGHLHRPQDVKRAETAARYSGSP
LAYSFSEAGHAKSVTVVDVHPGGAASVTEIPLAAGKPLVRWKATEGLAQVYRWCEEGKDQSCWVDLELHVTEPLTMEEIY
RLRKLHPGFVYIRPVFPQRVEEEAEVSREALSLEEMFCRFYKRQTGGQTPDEELVRLFLELAAEEEQEGGEE
>Mature_392_residues
MRILHTADWHLGRTLEGRSRLAEQEAFIDELIEIVEKEQIDAILMAGDVFDSVNPPAAAEQLFYESLARLSDKGRRPVAV
ISGNHDHPDRISAARTLLSDYHIFLFGRPEASVCRIDVPSCGETMMLAPLAYPSESRLAELLSSDHREAVLRDRYDDRIR
ALLEMMAASFTEKTVNIVMSHLYVAGGRTSDSERPIEVGGAYTVAATSLPKAAQYVALGHLHRPQDVKRAETAARYSGSP
LAYSFSEAGHAKSVTVVDVHPGGAASVTEIPLAAGKPLVRWKATEGLAQVYRWCEEGKDQSCWVDLELHVTEPLTMEEIY
RLRKLHPGFVYIRPVFPQRVEEEAEVSREALSLEEMFCRFYKRQTGGQTPDEELVRLFLELAAEEEQEGGEE

Specific function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sbcD family [H]

Homologues:

Organism=Escherichia coli, GI1786598, Length=407, Percent_Identity=30.2211302211302, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR004593 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 43809; Mature: 43809

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILHTADWHLGRTLEGRSRLAEQEAFIDELIEIVEKEQIDAILMAGDVFDSVNPPAAAE
CCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHCCCCCHHHH
QLFYESLARLSDKGRRPVAVISGNHDHPDRISAARTLLSDYHIFLFGRPEASVCRIDVPS
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCC
CGETMMLAPLAYPSESRLAELLSSDHREAVLRDRYDDRIRALLEMMAASFTEKTVNIVMS
CCCCEEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLYVAGGRTSDSERPIEVGGAYTVAATSLPKAAQYVALGHLHRPQDVKRAETAARYSGSP
HHHHCCCCCCCCCCCEECCCCEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
LAYSFSEAGHAKSVTVVDVHPGGAASVTEIPLAAGKPLVRWKATEGLAQVYRWCEEGKDQ
CEEECCCCCCCCEEEEEEECCCCCCCHHHCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCC
SCWVDLELHVTEPLTMEEIYRLRKLHPGFVYIRPVFPQRVEEEAEVSREALSLEEMFCRF
CEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
YKRQTGGQTPDEELVRLFLELAAEEEQEGGEE
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRILHTADWHLGRTLEGRSRLAEQEAFIDELIEIVEKEQIDAILMAGDVFDSVNPPAAAE
CCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHCCCCCHHHH
QLFYESLARLSDKGRRPVAVISGNHDHPDRISAARTLLSDYHIFLFGRPEASVCRIDVPS
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCC
CGETMMLAPLAYPSESRLAELLSSDHREAVLRDRYDDRIRALLEMMAASFTEKTVNIVMS
CCCCEEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLYVAGGRTSDSERPIEVGGAYTVAATSLPKAAQYVALGHLHRPQDVKRAETAARYSGSP
HHHHCCCCCCCCCCCEECCCCEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
LAYSFSEAGHAKSVTVVDVHPGGAASVTEIPLAAGKPLVRWKATEGLAQVYRWCEEGKDQ
CEEECCCCCCCCEEEEEEECCCCCCCHHHCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCC
SCWVDLELHVTEPLTMEEIYRLRKLHPGFVYIRPVFPQRVEEEAEVSREALSLEEMFCRF
CEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
YKRQTGGQTPDEELVRLFLELAAEEEQEGGEE
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 10568751; 1646786; 8493111 [H]