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The map label for this gene is comK [H]

Identifier: 138894259

GI number: 138894259

Start: 647409

End: 647957

Strand: Direct

Name: comK [H]

Synonym: GTNG_0585

Alternate gene names: 138894259

Gene position: 647409-647957 (Clockwise)

Preceding gene: 138894258

Following gene: 138894260

Centisome position: 18.24

GC content: 42.81

Gene sequence:

>549_bases
ATGAAAGTGAATGAATTTATCGTGCTAGAACATTTTGTCGTAAGCCGTTATACAATGGCAATTCTTCCGTACTTGTTGAA
CAGCGACATCTATGCAAAAGTCATTGAGGAAGATGGCGAATATATTGTCAAAAAAACGCCAACCGACATCATTAAACAGA
GCTGTGATTATTATGGATGCAGCTTCCAAGGTAGAAAAGAAGGAACAAAGGCGTTGATCGGCATCACTCATAAGGCACCG
ATCGCCGTCGAACCGTCCAATGGAATTTATGTCTTCCCGACTTCTTCCCCGAGAGATTCCGGCTGCGTTTGGTTGTCCCA
TATGCATGTCTATAGGTATGAACCTGCTAAATATGAGCGAACCGTCGTCTATTTCCGCAACGGAAAAAGCGTATTCCTCG
ATGTATCCTACAAATCCTTTATCAATCAATTATATCGAACGGCTCAATTGCGGACGAAACTGTCAGACCGAATGGAAGCA
AGAGAGCGCAAGCTACAATACATATTCCGCATGCAGCAGAAAAAAGAAAAAGATGTGCCAGAGCATTGA

Upstream 100 bases:

>100_bases
TGATAAAAAGACTAATAATTTTTTTCAAAATATAGAAAAATATAACTTTTGATGGTATGATAGAAGTAGTTATCAGTTGA
TTAGGAAAGGGGATGAATCG

Downstream 100 bases:

>100_bases
TGGTAAAAATGGGCTTTCACAAAGATGAGTTCAAATTGCACGACCGAGCGTGTAAAATAAAAATATAAACGGCATTTGAA
TGGAGAAAGATGCATGAATA

Product: competence transcription factor CTF

Products: NA

Alternate protein names: CTF; Competence protein K [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKVNEFIVLEHFVVSRYTMAILPYLLNSDIYAKVIEEDGEYIVKKTPTDIIKQSCDYYGCSFQGRKEGTKALIGITHKAP
IAVEPSNGIYVFPTSSPRDSGCVWLSHMHVYRYEPAKYERTVVYFRNGKSVFLDVSYKSFINQLYRTAQLRTKLSDRMEA
RERKLQYIFRMQQKKEKDVPEH

Sequences:

>Translated_182_residues
MKVNEFIVLEHFVVSRYTMAILPYLLNSDIYAKVIEEDGEYIVKKTPTDIIKQSCDYYGCSFQGRKEGTKALIGITHKAP
IAVEPSNGIYVFPTSSPRDSGCVWLSHMHVYRYEPAKYERTVVYFRNGKSVFLDVSYKSFINQLYRTAQLRTKLSDRMEA
RERKLQYIFRMQQKKEKDVPEH
>Mature_182_residues
MKVNEFIVLEHFVVSRYTMAILPYLLNSDIYAKVIEEDGEYIVKKTPTDIIKQSCDYYGCSFQGRKEGTKALIGITHKAP
IAVEPSNGIYVFPTSSPRDSGCVWLSHMHVYRYEPAKYERTVVYFRNGKSVFLDVSYKSFINQLYRTAQLRTKLSDRMEA
RERKLQYIFRMQQKKEKDVPEH

Specific function: Intermediate regulatory gene required for the expression of the late competence genes comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes [H]

COG id: COG4903

COG function: function code K; Genetic competence transcription factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010461 [H]

Pfam domain/function: PF06338 ComK [H]

EC number: NA

Molecular weight: Translated: 21356; Mature: 21356

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVNEFIVLEHFVVSRYTMAILPYLLNSDIYAKVIEEDGEYIVKKTPTDIIKQSCDYYGC
CCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCHHHHHHCCCCCCC
SFQGRKEGTKALIGITHKAPIAVEPSNGIYVFPTSSPRDSGCVWLSHMHVYRYEPAKYER
CCCCCCCCCEEEEEEECCCCEEEECCCCEEEEECCCCCCCCEEEEEEEEEEEECCCCCCE
TVVYFRNGKSVFLDVSYKSFINQLYRTAQLRTKLSDRMEARERKLQYIFRMQQKKEKDVP
EEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EH
CC
>Mature Secondary Structure
MKVNEFIVLEHFVVSRYTMAILPYLLNSDIYAKVIEEDGEYIVKKTPTDIIKQSCDYYGC
CCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCHHHHHHCCCCCCC
SFQGRKEGTKALIGITHKAPIAVEPSNGIYVFPTSSPRDSGCVWLSHMHVYRYEPAKYER
CCCCCCCCCEEEEEEECCCCEEEECCCCEEEEECCCCCCCCEEEEEEEEEEEECCCCCCE
TVVYFRNGKSVFLDVSYKSFINQLYRTAQLRTKLSDRMEARERKLQYIFRMQQKKEKDVP
EEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EH
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196543; 9579061; 9384377; 7783616; 11744713 [H]