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The map label for this gene is ythA [H]

Identifier: 138894192

GI number: 138894192

Start: 580693

End: 582039

Strand: Direct

Name: ythA [H]

Synonym: GTNG_0518

Alternate gene names: 138894192

Gene position: 580693-582039 (Clockwise)

Preceding gene: 138894191

Following gene: 138894193

Centisome position: 16.36

GC content: 48.63

Gene sequence:

>1347_bases
ATGAACGGCTATGATCCAGTGTTGCTTAGCCGTATTTTGACAGAATTGACGTTAACGGTCCATATTATTTACGCCACGAT
TGGTGTCGGGGTCCCGCTTATGATCGCTATTGCTCAGTGGGTTGGGATTCGCAAAAACGACATGCATTACATCTTGCTCG
CCCGACGTTGGACGCGCGGCTTTGTCATCACTGTAGCGGTCGGGGTGGTGACTGGAACGGCGATCGGCTTGCAGCTATCG
CTTTTATGGCCGAACTTTATGCAGCTGGCTGGTCAGGTGATCAGCTTGCCGCTATTCATGGAAACATTTGCTTTCTTTTT
TGAAGCCATTTTCTTGGGCATTTATTTGTACACATGGGATCGGTTCAAAAATCAAAAAAAACATTTGCTTTTGCTCATTC
CGGTGGCCATCGGCTCTTCGGCATCAGCCATGTTTATTACGATGGTGAACGCGTTTATGAATACGCCGCAAGGGTTTGAG
TTGAAAAACGGAGAGCTTGTCAACATTGATCCTATCGTGGCTATGTTCAACCCAGCGATGCCGACAAAGGTCGCTCATGT
GTTGGCAACGTCATATATGACGTCGGCATTCGTGCTCGCCTCGATCGCTGCTTGGCATTTATGGAAAGGCAACCGCCACA
TTTACCATCGTAAAGCACTTCATTTAACGATGAAAACAGCTTTTATTTTTTCCGTAGCTAGTGCGTTGGTCGGTGACTTA
TCCGGAAAATTTTTAGCCGAATACCAGCCAGAAAAGCTGGCAGCCGCTGAATGGCATTTTGAAACGAGTTCCCACGCGCC
GCTTATCTTGTTCGGCACGCTTGAAGAAGACAACGAAGTGAAATATGCCTTGGAAATCCCATATGCTCTGAGTATTTTGG
CCCATAACCATCCCGCTGCAGTTGTGACTGGACTGAATGATATTCCGGAAGATGAGCGTCCGCCGCTGTACATTCATTAC
TTATTTGATGTGATGGTTACGATCGGTGTGTTTTTAATGGTTGTCGCAGCCGTATATTGGCTTGGGTCAATTTTCCGATG
GAAATGGACGGCGAAAAATTGGTTTTTTGGGCTGTTAGTGGCAGGAGGGCCGTTGGCGATGATCGCGATTGAGGCTGGAT
GGTACTTAGCGGAAGTCGGGCGGCAACCGTGGATTTTGCGCGGCTATATGAAAACCGCAGAAGGGGCGACAACGTCCGCG
CATGTTGATACGATGCTTGTTTTGTTTTGCCTTTTGTATATAGTGTTGGTCATTGCAAGTGCAACAGTGCTCATTCGCAT
GTTCCGCCGCAACCCGGTCGAACGGGAGCTGGAAGAACGCGCGAATAGGGGGGAGGTGGCGCCATGA

Upstream 100 bases:

>100_bases
GAGCGGCATGAAAAAACGCTTGTATTTATTAGCTTTGCTGTTGCGGCAGTGGCGTTGCTTTCCTTGATTGGCCGCTTGTT
TTCATAAGGGGGGATGAATC

Downstream 100 bases:

>100_bases
CGCTCGAAGTCATCGGCATCTCGGTACTATGGCTGTTTTTGTTTGGCTACATTATTGTTGCCTCGATTGATTTCGGAGCC
GGGTTTTTCAGCGTTTATAG

Product: bd-type quinol oxidase subunit I

Products: ubiquinone-8; H2O [C]

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MNGYDPVLLSRILTELTLTVHIIYATIGVGVPLMIAIAQWVGIRKNDMHYILLARRWTRGFVITVAVGVVTGTAIGLQLS
LLWPNFMQLAGQVISLPLFMETFAFFFEAIFLGIYLYTWDRFKNQKKHLLLLIPVAIGSSASAMFITMVNAFMNTPQGFE
LKNGELVNIDPIVAMFNPAMPTKVAHVLATSYMTSAFVLASIAAWHLWKGNRHIYHRKALHLTMKTAFIFSVASALVGDL
SGKFLAEYQPEKLAAAEWHFETSSHAPLILFGTLEEDNEVKYALEIPYALSILAHNHPAAVVTGLNDIPEDERPPLYIHY
LFDVMVTIGVFLMVVAAVYWLGSIFRWKWTAKNWFFGLLVAGGPLAMIAIEAGWYLAEVGRQPWILRGYMKTAEGATTSA
HVDTMLVLFCLLYIVLVIASATVLIRMFRRNPVERELEERANRGEVAP

Sequences:

>Translated_448_residues
MNGYDPVLLSRILTELTLTVHIIYATIGVGVPLMIAIAQWVGIRKNDMHYILLARRWTRGFVITVAVGVVTGTAIGLQLS
LLWPNFMQLAGQVISLPLFMETFAFFFEAIFLGIYLYTWDRFKNQKKHLLLLIPVAIGSSASAMFITMVNAFMNTPQGFE
LKNGELVNIDPIVAMFNPAMPTKVAHVLATSYMTSAFVLASIAAWHLWKGNRHIYHRKALHLTMKTAFIFSVASALVGDL
SGKFLAEYQPEKLAAAEWHFETSSHAPLILFGTLEEDNEVKYALEIPYALSILAHNHPAAVVTGLNDIPEDERPPLYIHY
LFDVMVTIGVFLMVVAAVYWLGSIFRWKWTAKNWFFGLLVAGGPLAMIAIEAGWYLAEVGRQPWILRGYMKTAEGATTSA
HVDTMLVLFCLLYIVLVIASATVLIRMFRRNPVERELEERANRGEVAP
>Mature_448_residues
MNGYDPVLLSRILTELTLTVHIIYATIGVGVPLMIAIAQWVGIRKNDMHYILLARRWTRGFVITVAVGVVTGTAIGLQLS
LLWPNFMQLAGQVISLPLFMETFAFFFEAIFLGIYLYTWDRFKNQKKHLLLLIPVAIGSSASAMFITMVNAFMNTPQGFE
LKNGELVNIDPIVAMFNPAMPTKVAHVLATSYMTSAFVLASIAAWHLWKGNRHIYHRKALHLTMKTAFIFSVASALVGDL
SGKFLAEYQPEKLAAAEWHFETSSHAPLILFGTLEEDNEVKYALEIPYALSILAHNHPAAVVTGLNDIPEDERPPLYIHY
LFDVMVTIGVFLMVVAAVYWLGSIFRWKWTAKNWFFGLLVAGGPLAMIAIEAGWYLAEVGRQPWILRGYMKTAEGATTSA
HVDTMLVLFCLLYIVLVIASATVLIRMFRRNPVERELEERANRGEVAP

Specific function: Probable cytochrome [H]

COG id: COG1271

COG function: function code C; Cytochrome bd-type quinol oxidase, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome ubiquinol oxidase subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1787212, Length=514, Percent_Identity=26.0700389105058, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI87081779, Length=318, Percent_Identity=30.188679245283, Blast_Score=148, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002585 [H]

Pfam domain/function: PF01654 Bac_Ubq_Cox [H]

EC number: 1.10.3.- [C]

Molecular weight: Translated: 50196; Mature: 50196

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGYDPVLLSRILTELTLTVHIIYATIGVGVPLMIAIAQWVGIRKNDMHYILLARRWTRG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
FVITVAVGVVTGTAIGLQLSLLWPNFMQLAGQVISLPLFMETFAFFFEAIFLGIYLYTWD
EEEEEEHHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFKNQKKHLLLLIPVAIGSSASAMFITMVNAFMNTPQGFELKNGELVNIDPIVAMFNPAM
HHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEECCCEEEEECHHHHHCCCCC
PTKVAHVLATSYMTSAFVLASIAAWHLWKGNRHIYHRKALHLTMKTAFIFSVASALVGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHC
SGKFLAEYQPEKLAAAEWHFETSSHAPLILFGTLEEDNEVKYALEIPYALSILAHNHPAA
CCCHHHCCCCCHHHHHEEECCCCCCCCEEEEEECCCCCCEEEEEECCCEEEEEECCCCCE
VVTGLNDIPEDERPPLYIHYLFDVMVTIGVFLMVVAAVYWLGSIFRWKWTAKNWFFGLLV
EEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEE
AGGPLAMIAIEAGWYLAEVGRQPWILRGYMKTAEGATTSAHVDTMLVLFCLLYIVLVIAS
CCCCEEEEEEECCHHHHHHCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ATVLIRMFRRNPVERELEERANRGEVAP
HHHHHHHHHCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNGYDPVLLSRILTELTLTVHIIYATIGVGVPLMIAIAQWVGIRKNDMHYILLARRWTRG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
FVITVAVGVVTGTAIGLQLSLLWPNFMQLAGQVISLPLFMETFAFFFEAIFLGIYLYTWD
EEEEEEHHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFKNQKKHLLLLIPVAIGSSASAMFITMVNAFMNTPQGFELKNGELVNIDPIVAMFNPAM
HHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEECCCEEEEECHHHHHCCCCC
PTKVAHVLATSYMTSAFVLASIAAWHLWKGNRHIYHRKALHLTMKTAFIFSVASALVGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHC
SGKFLAEYQPEKLAAAEWHFETSSHAPLILFGTLEEDNEVKYALEIPYALSILAHNHPAA
CCCHHHCCCCCHHHHHEEECCCCCCCCEEEEEECCCCCCEEEEEECCCEEEEEECCCCCE
VVTGLNDIPEDERPPLYIHYLFDVMVTIGVFLMVVAAVYWLGSIFRWKWTAKNWFFGLLV
EEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEE
AGGPLAMIAIEAGWYLAEVGRQPWILRGYMKTAEGATTSAHVDTMLVLFCLLYIVLVIAS
CCCCEEEEEEECCHHHHHHCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ATVLIRMFRRNPVERELEERANRGEVAP
HHHHHHHHHCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ubiquinol-8; O2 [C]

Specific reaction: ubiquinol-8 + O2 = ubiquinone-8 + H2O [C]

General reaction: Oxidoreductases; Acting on diphenols and related substances as donors; With oxygen as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]