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The map label for this gene is lytE [H]

Identifier: 138894049

GI number: 138894049

Start: 427570

End: 428022

Strand: Reverse

Name: lytE [H]

Synonym: GTNG_0375

Alternate gene names: 138894049

Gene position: 428022-427570 (Counterclockwise)

Preceding gene: 138894054

Following gene: 138894047

Centisome position: 12.06

GC content: 40.18

Gene sequence:

>453_bases
ATGAAAAAATGGCTTACTCTTTTGTCTCTGTCAATGATTGTCCTATTTTCCTCCTTGTTTGTAAACGTTTCTGACACCAG
TGCAGCAGCTAATAAAACACGCCTGATCGCTGAAGCCAAAAAGCTTATCGGCACTCCTTATCGGTATGGCGGCACAACAC
CAAAAGGATTCGATTGCTCCGGGTTTGTTTATTACACACATAAAAAAGTGGGCGTTACTTTGCCCCGTTCTTCCAAAGAA
ATGTATAAAAAAGGTAAGTATGTACATAAGTCGAATTTAAAACCGGGAGATTTAGTGTTCTTTAACACTTCGAAACGAAC
AAAAGGCGTTTCCCATGTTGCGATTTACATTGGAAACAACCGAGTCATCCATGCCGTTTCGCGCGGTGTTAAAATTGATA
ATTTAAACAGCTCCTACTGGAAAACGAAATATGTCGGAGCTAAACGGTTGTAA

Upstream 100 bases:

>100_bases
ATTATTTAATTCAACTGTAAAAAACAAGACTGTTTTCCTCTGTTATACTATAGTCAAATGATGTCGAATCGAAAGAGATC
TTGTCGGGGGTTTAGGGAAA

Downstream 100 bases:

>100_bases
TGGTTTCAGTGAACGAAGAGCTCTCTGTCCTATTAGGCTCGCCTAATAGGCAGGGAGTTTTATTATGGCCGATGGTGTTG
CAAAACTAGAGTAAAAACTC

Product: cell wall lytic activity

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP33; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytE; Phosphatase-associated protein papQ [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKKWLTLLSLSMIVLFSSLFVNVSDTSAAANKTRLIAEAKKLIGTPYRYGGTTPKGFDCSGFVYYTHKKVGVTLPRSSKE
MYKKGKYVHKSNLKPGDLVFFNTSKRTKGVSHVAIYIGNNRVIHAVSRGVKIDNLNSSYWKTKYVGAKRL

Sequences:

>Translated_150_residues
MKKWLTLLSLSMIVLFSSLFVNVSDTSAAANKTRLIAEAKKLIGTPYRYGGTTPKGFDCSGFVYYTHKKVGVTLPRSSKE
MYKKGKYVHKSNLKPGDLVFFNTSKRTKGVSHVAIYIGNNRVIHAVSRGVKIDNLNSSYWKTKYVGAKRL
>Mature_150_residues
MKKWLTLLSLSMIVLFSSLFVNVSDTSAAANKTRLIAEAKKLIGTPYRYGGTTPKGFDCSGFVYYTHKKVGVTLPRSSKE
MYKKGKYVHKSNLKPGDLVFFNTSKRTKGVSHVAIYIGNNRVIHAVSRGVKIDNLNSSYWKTKYVGAKRL

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1788501, Length=121, Percent_Identity=45.4545454545455, Blast_Score=104, Evalue=2e-24,
Organism=Escherichia coli, GI1787944, Length=116, Percent_Identity=43.9655172413793, Blast_Score=103, Evalue=5e-24,
Organism=Escherichia coli, GI1788001, Length=109, Percent_Identity=45.8715596330275, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1786421, Length=121, Percent_Identity=35.5371900826446, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 16787; Mature: 16787

Theoretical pI: Translated: 10.89; Mature: 10.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKWLTLLSLSMIVLFSSLFVNVSDTSAAANKTRLIAEAKKLIGTPYRYGGTTPKGFDCS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GFVYYTHKKVGVTLPRSSKEMYKKGKYVHKSNLKPGDLVFFNTSKRTKGVSHVAIYIGNN
CEEEEEECEEEEECCCCCHHHHHCCCEEECCCCCCCCEEEEECCCCCCCCEEEEEEECCC
RVIHAVSRGVKIDNLNSSYWKTKYVGAKRL
EEEEEECCCEEEECCCCCCEEEECCCCCCC
>Mature Secondary Structure
MKKWLTLLSLSMIVLFSSLFVNVSDTSAAANKTRLIAEAKKLIGTPYRYGGTTPKGFDCS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GFVYYTHKKVGVTLPRSSKEMYKKGKYVHKSNLKPGDLVFFNTSKRTKGVSHVAIYIGNN
CEEEEEECEEEEECCCCCHHHHHCCCEEECCCCCCCCEEEEECCCCCCCCEEEEEEECCC
RVIHAVSRGVKIDNLNSSYWKTKYVGAKRL
EEEEEECCCEEEECCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457885; 9579061; 9384377; 8045898 [H]