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The map label for this gene is pucA [H]

Identifier: 138894031

GI number: 138894031

Start: 407824

End: 408852

Strand: Reverse

Name: pucA [H]

Synonym: GTNG_0357

Alternate gene names: 138894031

Gene position: 408852-407824 (Counterclockwise)

Preceding gene: 138894032

Following gene: 138894030

Centisome position: 11.52

GC content: 57.05

Gene sequence:

>1029_bases
ATGGAAAGCTACTATGCCGTGCTCGATGCCATGGCCGCTGCGCCGGGCGATGGTGTATTCGCCATCATTATTGACGTCGA
AGGTTCAGCCTATCAAAAGGAAGGCACATGGATGTGGATCGAAGCAAGTGGAAAGACAACTGGCTTATTAAGCGGAGGCT
GCTTTGAGGAAGCGGTGGCCGCGCACGCCCTCGACGTGCTGTCAAACCGTCAGGCGACGTCCATATCGTTTGACTTGCGC
GCCGAAGATGATTGGTCTTGGGGACAAGGGGCTGGTTGCAACGGCCTTGTCCGCATTTGGCTTGAACCGGTGACAAGCAA
CACCAAACCTGATTGGCTGGCATTGAAACGCTGCCTTGACCGCGGTGAACATGTGTTTATGGCTCGAAGCATTACCGATC
CGAGGGAGCAGCCGTTTTTCCAAAGCGAAACGGGGGAGCGCTTCGGCGGCTATTCTTCGCCGCCGAGGCCGGAATGGCTG
AAAGAGTTGCATGGCACACCGTTTTTCCGTGGACGGAACGGTGTGTATGAAACGGAAGAGGACACGTTTTTCATTCAGCA
TTTTTGGCCAAAACCGCGTCTTACGATTTTCGGCGCCGGTCCCGACGCTCCGCCACTCGTCTCGGCAGCTAAAGCCGCTG
GGTTTTCCGTCACGGTCAGCGACTGGCGCCCGGCGTTTTGTCAACCGTCGCACGTGCCGGACGCGGACGCTTGGGTCGTC
GGCTTTCCGCATGAAACCATTCCGAAACTTCACCTTACCGAGCGCGACTTTGTCGTTATTATGACTCACCAGTTTGAGCG
CGACCGGGAACTTATGAGATGGTTAGCCGACATACCGCTCGCCTACCTCGGCGTGCTTGGACCGCGGCGGCGCACAGACC
GACTCTTTCCTTCTGGAACGGCCCCGCCGTTTGTCCGTTCACCAATTGGACTGCCAATTGGAGCGCGCAGCCCGCATGAA
ATTGCTATAAGCATCACCGCCGAACTAATTAACGTGCTGCGCGGAGGGCCGATGGAGACTGCACGATGA

Upstream 100 bases:

>100_bases
CTTGTGCCAAAGACAGCTACCATTACGAACGTTTATTGATCGTCACGCTTTACTTTCATCAGCTTAGCCGCCTTTGGTGC
AACGCGGAAGGAGGATAAGC

Downstream 100 bases:

>100_bases
GTGAACTCACGATTGCAGGCATTTACTTAGCCGCTGGACAGAGTCGGCGGATGGGAACGGATAAACGCGCCTTGCCTTGG
GGGGATGGGACGCTTGGGAC

Product: xanthine dehydrogenase

Products: NA

Alternate protein names: XDHase subunit A [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MESYYAVLDAMAAAPGDGVFAIIIDVEGSAYQKEGTWMWIEASGKTTGLLSGGCFEEAVAAHALDVLSNRQATSISFDLR
AEDDWSWGQGAGCNGLVRIWLEPVTSNTKPDWLALKRCLDRGEHVFMARSITDPREQPFFQSETGERFGGYSSPPRPEWL
KELHGTPFFRGRNGVYETEEDTFFIQHFWPKPRLTIFGAGPDAPPLVSAAKAAGFSVTVSDWRPAFCQPSHVPDADAWVV
GFPHETIPKLHLTERDFVVIMTHQFERDRELMRWLADIPLAYLGVLGPRRRTDRLFPSGTAPPFVRSPIGLPIGARSPHE
IAISITAELINVLRGGPMETAR

Sequences:

>Translated_342_residues
MESYYAVLDAMAAAPGDGVFAIIIDVEGSAYQKEGTWMWIEASGKTTGLLSGGCFEEAVAAHALDVLSNRQATSISFDLR
AEDDWSWGQGAGCNGLVRIWLEPVTSNTKPDWLALKRCLDRGEHVFMARSITDPREQPFFQSETGERFGGYSSPPRPEWL
KELHGTPFFRGRNGVYETEEDTFFIQHFWPKPRLTIFGAGPDAPPLVSAAKAAGFSVTVSDWRPAFCQPSHVPDADAWVV
GFPHETIPKLHLTERDFVVIMTHQFERDRELMRWLADIPLAYLGVLGPRRRTDRLFPSGTAPPFVRSPIGLPIGARSPHE
IAISITAELINVLRGGPMETAR
>Mature_342_residues
MESYYAVLDAMAAAPGDGVFAIIIDVEGSAYQKEGTWMWIEASGKTTGLLSGGCFEEAVAAHALDVLSNRQATSISFDLR
AEDDWSWGQGAGCNGLVRIWLEPVTSNTKPDWLALKRCLDRGEHVFMARSITDPREQPFFQSETGERFGGYSSPPRPEWL
KELHGTPFFRGRNGVYETEEDTFFIQHFWPKPRLTIFGAGPDAPPLVSAAKAAGFSVTVSDWRPAFCQPSHVPDADAWVV
GFPHETIPKLHLTERDFVVIMTHQFERDRELMRWLADIPLAYLGVLGPRRRTDRLFPSGTAPPFVRSPIGLPIGARSPHE
IAISITAELINVLRGGPMETAR

Specific function: Oxidizes hypoxanthine and xanthine to uric acid. PucA subunit could exert a molybdenum cofactor recruiting function [H]

COG id: COG1975

COG function: function code O; Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789240, Length=179, Percent_Identity=29.608938547486, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003777 [H]

Pfam domain/function: PF02625 XdhC_CoxI [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 37954; Mature: 37954

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESYYAVLDAMAAAPGDGVFAIIIDVEGSAYQKEGTWMWIEASGKTTGLLSGGCFEEAVA
CCHHHHHHHHHHCCCCCCEEEEEEECCCCCEECCCCEEEEEECCCEEEEECCCCHHHHHH
AHALDVLSNRQATSISFDLRAEDDWSWGQGAGCNGLVRIWLEPVTSNTKPDWLALKRCLD
HHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHC
RGEHVFMARSITDPREQPFFQSETGERFGGYSSPPRPEWLKELHGTPFFRGRNGVYETEE
CCCEEEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEECCCCCCCCCCC
DTFFIQHFWPKPRLTIFGAGPDAPPLVSAAKAAGFSVTVSDWRPAFCQPSHVPDADAWVV
CEEEEEEECCCCCEEEEECCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEE
GFPHETIPKLHLTERDFVVIMTHQFERDRELMRWLADIPLAYLGVLGPRRRTDRLFPSGT
ECCHHHCCCEEECCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCC
APPFVRSPIGLPIGARSPHEIAISITAELINVLRGGPMETAR
CCCHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MESYYAVLDAMAAAPGDGVFAIIIDVEGSAYQKEGTWMWIEASGKTTGLLSGGCFEEAVA
CCHHHHHHHHHHCCCCCCEEEEEEECCCCCEECCCCEEEEEECCCEEEEECCCCHHHHHH
AHALDVLSNRQATSISFDLRAEDDWSWGQGAGCNGLVRIWLEPVTSNTKPDWLALKRCLD
HHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHC
RGEHVFMARSITDPREQPFFQSETGERFGGYSSPPRPEWLKELHGTPFFRGRNGVYETEE
CCCEEEEEECCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEECCCCCCCCCCC
DTFFIQHFWPKPRLTIFGAGPDAPPLVSAAKAAGFSVTVSDWRPAFCQPSHVPDADAWVV
CEEEEEEECCCCCEEEEECCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEE
GFPHETIPKLHLTERDFVVIMTHQFERDRELMRWLADIPLAYLGVLGPRRRTDRLFPSGT
ECCHHHCCCEEECCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCC
APPFVRSPIGLPIGARSPHEIAISITAELINVLRGGPMETAR
CCCHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]