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The map label for this gene is alr [H]

Identifier: 138893881

GI number: 138893881

Start: 219008

End: 220162

Strand: Direct

Name: alr [H]

Synonym: GTNG_0205

Alternate gene names: 138893881

Gene position: 219008-220162 (Clockwise)

Preceding gene: 138893880

Following gene: 138893882

Centisome position: 6.17

GC content: 51.95

Gene sequence:

>1155_bases
ATGGACAACTTTCACCGCGATACGTGGGCAGAAATCGACTTGGATGCTATTTACGACAACGTCGCGAATTTGCGACGCTT
TTTACCGGATGGAACACAGGTTATGGCCGTTGTAAAAGCGAACGCCTACGGGCATGGTGACGCCCAAGTGGCGACAACGG
CGCTAGAAGCCGGTGCTTCCTACTTAGCCGTCGCCATTTTGGACGAGGCGCTCGCTTTAAGACAAAAAGGCATCAATGCG
CCCATTTTAGTGCTTGGGGCGTCCCGCCCGGCCGATGTGGAGCTAGCCGCTCGACATCGCATTACTTTAACCGTGTTTCG
CGCCGATTGGTTAGAGGAGGCGGCATCGATTTATAACGGCTCGACTCCCGTTCATCTGCATTTAAAAATGGATACTGGAA
TGGGACGGCTCGGGGTAAAAGACGAGGAGGAGACGAAGCGTATTACGACGCTGATTGACCGCCACCCATCCTTTATCCTT
GAAGGGGTATATACGCATTTTGCGACGGCTGATGAAGTGAATACAGACTATCTTTCTTATCAATATCGCCGCTTTTTGCA
TATGCTCGAATGGCTGCCATCGCGGCCGCCGATCGTTCATTGTGCCAACAGTGCGACGGTACTCCGCTTTCCCGAGCGAG
CGTTCAATATGGCCCGCTTCGGCATTTCCATGTACGGACTCGCTCCATCGCCAAGCATCAAGCCGTTGCTTCCATACGAA
CTAAAGGAGGCGTTTTCGCTTCATAGCCGCCTCGTGCATGTGAAAAGATTGCAACCGGGTGAAAAGGTGAGTTACGGAGC
GACGTATACCGCACAAGAGGAAGAGTGGATCGGTACGCTCCCGATCGGCTATGCGGACGGATGGCTCCGTCGCCTGCAAC
ATTTTCATGTGCTCGTGAACGGGCAAAAGGCGCCAATTGTCGGCCGGATTTGCATGGATCAATGCATGATTCGCCTGCCT
GAACCGTTGCCAGTCGGTACGAAGGTAACATTGATCGGTCGCCAAGGAGATGAGTTCATTTCTGTTGATGATGTCGCCCG
CTATTTGGAAACGATTAATTACGAAGTGCCTTGTACAATCAGTTATCGGGTGCCCCGTATTTTTTTCCGAAATAAGCGTA
TAATGGAAGTGAGAAATGCTGTTTGCCACGGGTGA

Upstream 100 bases:

>100_bases
ACCTATTCCGTCTTCACTACAGACGTGGTAAACTAAGAAAGAATGAAAACAAATTTAAACGCTTTCAAAACTTACGTGAT
TAGAAAGGCAGCGAGAGAGG

Downstream 100 bases:

>100_bases
AGCGATGCATACTTTGCTTCAGAAGGCAAAGGATAGAAAAGGGAGAAATGACTTTGCAGCGCCGTTGTTTAATGGTATCA
TGAAATGGAAGCAATGAATG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MDNFHRDTWAEIDLDAIYDNVANLRRFLPDGTQVMAVVKANAYGHGDAQVATTALEAGASYLAVAILDEALALRQKGINA
PILVLGASRPADVELAARHRITLTVFRADWLEEAASIYNGSTPVHLHLKMDTGMGRLGVKDEEETKRITTLIDRHPSFIL
EGVYTHFATADEVNTDYLSYQYRRFLHMLEWLPSRPPIVHCANSATVLRFPERAFNMARFGISMYGLAPSPSIKPLLPYE
LKEAFSLHSRLVHVKRLQPGEKVSYGATYTAQEEEWIGTLPIGYADGWLRRLQHFHVLVNGQKAPIVGRICMDQCMIRLP
EPLPVGTKVTLIGRQGDEFISVDDVARYLETINYEVPCTISYRVPRIFFRNKRIMEVRNAVCHG

Sequences:

>Translated_384_residues
MDNFHRDTWAEIDLDAIYDNVANLRRFLPDGTQVMAVVKANAYGHGDAQVATTALEAGASYLAVAILDEALALRQKGINA
PILVLGASRPADVELAARHRITLTVFRADWLEEAASIYNGSTPVHLHLKMDTGMGRLGVKDEEETKRITTLIDRHPSFIL
EGVYTHFATADEVNTDYLSYQYRRFLHMLEWLPSRPPIVHCANSATVLRFPERAFNMARFGISMYGLAPSPSIKPLLPYE
LKEAFSLHSRLVHVKRLQPGEKVSYGATYTAQEEEWIGTLPIGYADGWLRRLQHFHVLVNGQKAPIVGRICMDQCMIRLP
EPLPVGTKVTLIGRQGDEFISVDDVARYLETINYEVPCTISYRVPRIFFRNKRIMEVRNAVCHG
>Mature_384_residues
MDNFHRDTWAEIDLDAIYDNVANLRRFLPDGTQVMAVVKANAYGHGDAQVATTALEAGASYLAVAILDEALALRQKGINA
PILVLGASRPADVELAARHRITLTVFRADWLEEAASIYNGSTPVHLHLKMDTGMGRLGVKDEEETKRITTLIDRHPSFIL
EGVYTHFATADEVNTDYLSYQYRRFLHMLEWLPSRPPIVHCANSATVLRFPERAFNMARFGISMYGLAPSPSIKPLLPYE
LKEAFSLHSRLVHVKRLQPGEKVSYGATYTAQEEEWIGTLPIGYADGWLRRLQHFHVLVNGQKAPIVGRICMDQCMIRLP
EPLPVGTKVTLIGRQGDEFISVDDVARYLETINYEVPCTISYRVPRIFFRNKRIMEVRNAVCHG

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=366, Percent_Identity=33.879781420765, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1790487, Length=363, Percent_Identity=33.6088154269972, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43304; Mature: 43304

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00395 ALANINE_RACEMASE ; PS00923 ASP_GLU_RACEMASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNFHRDTWAEIDLDAIYDNVANLRRFLPDGTQVMAVVKANAYGHGDAQVATTALEAGAS
CCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCH
YLAVAILDEALALRQKGINAPILVLGASRPADVELAARHRITLTVFRADWLEEAASIYNG
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCEEEEEEEEHHHHHHHHHHHCC
STPVHLHLKMDTGMGRLGVKDEEETKRITTLIDRHPSFILEGVYTHFATADEVNTDYLSY
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHH
QYRRFLHMLEWLPSRPPIVHCANSATVLRFPERAFNMARFGISMYGLAPSPSIKPLLPYE
HHHHHHHHHHHCCCCCCEEEECCCCEEEECCHHHHHHHHHCEEEEECCCCCCCCCCCCHH
LKEAFSLHSRLVHVKRLQPGEKVSYGATYTAQEEEWIGTLPIGYADGWLRRLQHFHVLVN
HHHHHHHHHHHHHHHHCCCCCCEECCEEEECCCCCCEECCCCCCHHHHHHHHHHEEEEEC
GQKAPIVGRICMDQCMIRLPEPLPVGTKVTLIGRQGDEFISVDDVARYLETINYEVPCTI
CCCCCEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEECHHHHHHHHHHCCCCCCEEE
SYRVPRIFFRNKRIMEVRNAVCHG
EECCCEEEECCCHHHHHHHHHCCC
>Mature Secondary Structure
MDNFHRDTWAEIDLDAIYDNVANLRRFLPDGTQVMAVVKANAYGHGDAQVATTALEAGAS
CCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCH
YLAVAILDEALALRQKGINAPILVLGASRPADVELAARHRITLTVFRADWLEEAASIYNG
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCEEEEEEEEHHHHHHHHHHHCC
STPVHLHLKMDTGMGRLGVKDEEETKRITTLIDRHPSFILEGVYTHFATADEVNTDYLSY
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHH
QYRRFLHMLEWLPSRPPIVHCANSATVLRFPERAFNMARFGISMYGLAPSPSIKPLLPYE
HHHHHHHHHHHCCCCCCEEEECCCCEEEECCHHHHHHHHHCEEEEECCCCCCCCCCCCHH
LKEAFSLHSRLVHVKRLQPGEKVSYGATYTAQEEEWIGTLPIGYADGWLRRLQHFHVLVN
HHHHHHHHHHHHHHHHCCCCCCEECCEEEECCCCCCEECCCCCCHHHHHHHHHHEEEEEC
GQKAPIVGRICMDQCMIRLPEPLPVGTKVTLIGRQGDEFISVDDVARYLETINYEVPCTI
CCCCCEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEECHHHHHHHHHHCCCCCCEEE
SYRVPRIFFRNKRIMEVRNAVCHG
EECCCEEEECCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA