Click here to switch to the map view.

The map label for this gene is acpS

Identifier: 138893879

GI number: 138893879

Start: 217231

End: 217620

Strand: Direct

Name: acpS

Synonym: GTNG_0203

Alternate gene names: 138893879

Gene position: 217231-217620 (Clockwise)

Preceding gene: 138893877

Following gene: 138893880

Centisome position: 6.12

GC content: 53.08

Gene sequence:

>390_bases
ATGATCGTTGGTATCGGCATTGATATTGTAGAGCTGGAGCGGATTCAATCACTCCTTGAGCGCAACCGCAAATTCCTTGA
CCGGATTTTAACGCCACGAGAGAGGGAGCAGTTTGATCAGCTAGCGCCTGCTAGACAAGTGGAATTTCTCGCTGGACGGT
TTGCGGCGAAGGAAGCGTACGCCAAAGCGCTTGGGACGGGGATCGGGCGACACGTATCGTTTCAGGACATTGAGATTGTT
TCCGATGAGTATGGAAAACCGAGCATTGCTGCCCGTCGCGACGGAGAAGTTATTCATCTATCCATTTCCCATAGCCGTGA
CTATGCGATCGCCCAAGTCATCATTGAGCGCTTCGGGCCGGCCAAGCCATCAGATGCTTGCCACGGCTAG

Upstream 100 bases:

>100_bases
GCAAGTGGGGAAGGTCATGTCCGTTTTTTATAAGCCATCTTATGCACAAAGAGTGTAAAAAATTTGTCGGATCACATAGC
ACGGATAGGTGGAGAAAGTG

Downstream 100 bases:

>100_bases
TCTGCATATTCTAGACAGTTGTCTCATATATTGTAGTGCATAGACAGAAATCGATATATGAGGCAAAGGGGTTGAAGCGA
TGGGTAGAAAGGTGCTTTGG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MIVGIGIDIVELERIQSLLERNRKFLDRILTPREREQFDQLAPARQVEFLAGRFAAKEAYAKALGTGIGRHVSFQDIEIV
SDEYGKPSIAARRDGEVIHLSISHSRDYAIAQVIIERFGPAKPSDACHG

Sequences:

>Translated_129_residues
MIVGIGIDIVELERIQSLLERNRKFLDRILTPREREQFDQLAPARQVEFLAGRFAAKEAYAKALGTGIGRHVSFQDIEIV
SDEYGKPSIAARRDGEVIHLSISHSRDYAIAQVIIERFGPAKPSDACHG
>Mature_129_residues
MIVGIGIDIVELERIQSLLERNRKFLDRILTPREREQFDQLAPARQVEFLAGRFAAKEAYAKALGTGIGRHVSFQDIEIV
SDEYGKPSIAARRDGEVIHLSISHSRDYAIAQVIIERFGPAKPSDACHG

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=127, Percent_Identity=38.5826771653543, Blast_Score=76, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_GEOTN (A4IJT3)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001124332.1
- ProteinModelPortal:   A4IJT3
- SMR:   A4IJT3
- STRING:   A4IJT3
- GeneID:   4965056
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_0203
- NMPDR:   fig|420246.5.peg.202
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   VHVSITH
- PhylomeDB:   A4IJT3
- ProtClustDB:   PRK00070
- BioCyc:   GTHE420246:GTNG_0203-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14429; Mature: 14429

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGIGIDIVELERIQSLLERNRKFLDRILTPREREQFDQLAPARQVEFLAGRFAAKEAY
CEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
AKALGTGIGRHVSFQDIEIVSDEYGKPSIAARRDGEVIHLSISHSRDYAIAQVIIERFGP
HHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCC
AKPSDACHG
CCCCCCCCC
>Mature Secondary Structure
MIVGIGIDIVELERIQSLLERNRKFLDRILTPREREQFDQLAPARQVEFLAGRFAAKEAY
CEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
AKALGTGIGRHVSFQDIEIVSDEYGKPSIAARRDGEVIHLSISHSRDYAIAQVIIERFGP
HHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCC
AKPSDACHG
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA