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The map label for this gene is dapB [H]

Identifier: 126696376

GI number: 126696376

Start: 896090

End: 896938

Strand: Reverse

Name: dapB [H]

Synonym: P9301_10381

Alternate gene names: 126696376

Gene position: 896938-896090 (Counterclockwise)

Preceding gene: 126696378

Following gene: 126696375

Centisome position: 54.63

GC content: 33.92

Gene sequence:

>849_bases
ATGATTGAAAATTCTAAAAAACCCATACCAGTACTTGTATCCGGAGCTTTAGGCAGAATGGGTAGCGAAGTTGTTAATAC
TGTATTAAATTCTAAAGATTGTGAACTTGTTGCAGCAATCGACATAAACGAAAAGAATAATGGCTCAAATATTTCTGAAT
TATTGAAGGTAAAAAATTGTGATGTTTTTGTTTCAAATGATTTTGAAGGAACTTTATGTTCTGTTAGTCAAAACTATAGA
AATGAAAATATCAAACCTGTGCTCGTTGATTTCACTCATCCTGATTCTGTATATGAAAATACCAGATCAGCTATTGCATA
TGGTGTGTCACCAGTAGTAGGAACTACAGGTCTAAGCCCTTCTCAAATACAAGATTTGTCTGTTTTTGCTCAGAAAGCAT
CTGTTGGTTGCGCAATAATTCCAAATTTTTCAGTAGGTATGGTTCTTCTTCAGCAGGCAGCATCGGTAGCTGCAAGGTTT
TACGACAATATCGAATTAATAGAGATGCACCATAATCAAAAAGCTGATTCTCCTAGTGGGACGTGTATAAAAACTGCAGA
AATGATTGAAGAATATCCAAAGAAATTTAATCAGAATCTAGTAAAAGAGTCTGAGTTATTGAAAGGTGTAAGGGGTGGGC
TTAGAGATTCTGGAATTAATATACATTCTGTACGATTACCAGGATTACTCGCTCATCAGTTAGTAATTATGGGATCTCAA
GGTGAAACTTACACAATTAAGCATGACACTATTGATAGAAAGGCATATATGCCAGGAGTTTTACAGGCTATTAAAAAAAT
TGGTAATTATGAAACTTTAGTTTACGGACTTGAAAAATTGATTTTTTAA

Upstream 100 bases:

>100_bases
ATTTTCTTTAAGTATTTCTACCAGCCTACGAATGAAAAGACGTTATTGTGTGCAATATAAATAGCGTGTAACAACCTTTA
AAAAAAAATTTTTTAAAAAA

Downstream 100 bases:

>100_bases
AATGTTAATTCCAATTAATTCAGGTCAAATTTCAAAACTTATTCCTGCAGTTGGTACAGGAAGTCAATTTAAGTACGCTT
TGGGGAATCCGAGAAAAATT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MIENSKKPIPVLVSGALGRMGSEVVNTVLNSKDCELVAAIDINEKNNGSNISELLKVKNCDVFVSNDFEGTLCSVSQNYR
NENIKPVLVDFTHPDSVYENTRSAIAYGVSPVVGTTGLSPSQIQDLSVFAQKASVGCAIIPNFSVGMVLLQQAASVAARF
YDNIELIEMHHNQKADSPSGTCIKTAEMIEEYPKKFNQNLVKESELLKGVRGGLRDSGINIHSVRLPGLLAHQLVIMGSQ
GETYTIKHDTIDRKAYMPGVLQAIKKIGNYETLVYGLEKLIF

Sequences:

>Translated_282_residues
MIENSKKPIPVLVSGALGRMGSEVVNTVLNSKDCELVAAIDINEKNNGSNISELLKVKNCDVFVSNDFEGTLCSVSQNYR
NENIKPVLVDFTHPDSVYENTRSAIAYGVSPVVGTTGLSPSQIQDLSVFAQKASVGCAIIPNFSVGMVLLQQAASVAARF
YDNIELIEMHHNQKADSPSGTCIKTAEMIEEYPKKFNQNLVKESELLKGVRGGLRDSGINIHSVRLPGLLAHQLVIMGSQ
GETYTIKHDTIDRKAYMPGVLQAIKKIGNYETLVYGLEKLIF
>Mature_282_residues
MIENSKKPIPVLVSGALGRMGSEVVNTVLNSKDCELVAAIDINEKNNGSNISELLKVKNCDVFVSNDFEGTLCSVSQNYR
NENIKPVLVDFTHPDSVYENTRSAIAYGVSPVVGTTGLSPSQIQDLSVFAQKASVGCAIIPNFSVGMVLLQQAASVAARF
YDNIELIEMHHNQKADSPSGTCIKTAEMIEEYPKKFNQNLVKESELLKGVRGGLRDSGINIHSVRLPGLLAHQLVIMGSQ
GETYTIKHDTIDRKAYMPGVLQAIKKIGNYETLVYGLEKLIF

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=279, Percent_Identity=26.1648745519713, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 30776; Mature: 30776

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIENSKKPIPVLVSGALGRMGSEVVNTVLNSKDCELVAAIDINEKNNGSNISELLKVKNC
CCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHCCC
DVFVSNDFEGTLCSVSQNYRNENIKPVLVDFTHPDSVYENTRSAIAYGVSPVVGTTGLSP
EEEEECCCCCEEEHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCH
SQIQDLSVFAQKASVGCAIIPNFSVGMVLLQQAASVAARFYDNIELIEMHHNQKADSPSG
HHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
TCIKTAEMIEEYPKKFNQNLVKESELLKGVRGGLRDSGINIHSVRLPGLLAHQLVIMGSQ
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHEEEEEECCC
GETYTIKHDTIDRKAYMPGVLQAIKKIGNYETLVYGLEKLIF
CCEEEEECCCCCHHHCCHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIENSKKPIPVLVSGALGRMGSEVVNTVLNSKDCELVAAIDINEKNNGSNISELLKVKNC
CCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHCCC
DVFVSNDFEGTLCSVSQNYRNENIKPVLVDFTHPDSVYENTRSAIAYGVSPVVGTTGLSP
EEEEECCCCCEEEHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCH
SQIQDLSVFAQKASVGCAIIPNFSVGMVLLQQAASVAARFYDNIELIEMHHNQKADSPSG
HHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
TCIKTAEMIEEYPKKFNQNLVKESELLKGVRGGLRDSGINIHSVRLPGLLAHQLVIMGSQ
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHEEEEEECCC
GETYTIKHDTIDRKAYMPGVLQAIKKIGNYETLVYGLEKLIF
CCEEEEECCCCCHHHCCHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]