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The map label for this gene is tqsA [H]

Identifier: 126696270

GI number: 126696270

Start: 801749

End: 802792

Strand: Reverse

Name: tqsA [H]

Synonym: P9301_09321

Alternate gene names: 126696270

Gene position: 802792-801749 (Counterclockwise)

Preceding gene: 126696271

Following gene: 126696262

Centisome position: 48.89

GC content: 26.72

Gene sequence:

>1044_bases
TTGAATAGTTTATCATATTTCAAGTTAGTAGTAATATTAATCACTTTATTAATAGTATGGACGCTAAAGGATTTTCTCCT
ACTAATAATTTGTGCTTTAGTAATTTCAAATATTGTATGTAATTTATCTAATCAAATCCAAAAAGGTTTGAAAATTCCTC
GATCGATTTCATTGTTTCTTGTCTTAGCCGCCATATCAGTAATAATATTTACTATTTTTATTATTGTATTACCTCCGTTT
ATAAAAGAATTCAATGAAATACTAGTTGAAATTCCAAATGGTTTATCAAAAATAAATACATTGATCAATACAAATCTGAA
CAAATTTAATAGCTTATTTTATGGCGAACAATCAGAAAATGTTATAGACATATTCAGTCTAATTAATAATGTAGTTACCA
TTCCAGATGTCTCAACTATTGCAAAAGCTATTCAAGAAAGTTTTAAGAATTTAATTAATATTGCGGGGAATCTAGGTTCA
GGTCTTTTGAGATTAATATTCGTATTAGCAGTGAGTTTGATGATTTCTATTGAACCAAAACAATATAAAGAAAATATACT
TCTATTAATACCAAAAAATTACCGTAATAAATTTAGAAATATTCTGGAAAAATGCAATATTGCATTAGCAAATTGGACCT
TTTCTATGGTTATAAGCTCATTATCAGTAGGTTTATTATCATTAATAGTTTTATCTATATTAGATGTCAAATACGTTGTC
TCGAATGCTTTAATAGCAATGGTTCTTAATATAATTCCGAATATAGGTCCAGTTATTAGTGGTATATTTCCAATCTCAAT
TGCACTACTAGATAATTTTTGGAAACCACTGGCAGTTTTAGGATCATATGTAATCATTCAAAATATTGAAAGCTATATCA
TAATGCCATCTATAATGAAGAAAAAAGCAAACCTACTTCCTGGTTTGACATTAATATCACAATTTGGATTTACCTTCATT
TTTGGTCCATTAGGCTTAATACTTTCTCTTCCATTAGCAGTAGTAATACAGGTTTTAATCAAAGAATCATTTAAAGATAT
TTAA

Upstream 100 bases:

>100_bases
AAGAACACACCAGACTTTGACAGATTTATGAGATTTGCAAATAGTTATGCCAAATCAAATGGATTAGGATATTCTGAAAA
GAAGTAGAAAATCATGAAAA

Downstream 100 bases:

>100_bases
AAACTACTTAATTAATTTTTTATATAAATATGGGTATGAAAAAAGTATAAAGATAGCTAAGGGATGTTTACCAATAGCAA
AATATAGAGAACTAAAAGTA

Product: permease

Products: NA

Alternate protein names: Transport of quorum-sensing signal protein [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MNSLSYFKLVVILITLLIVWTLKDFLLLIICALVISNIVCNLSNQIQKGLKIPRSISLFLVLAAISVIIFTIFIIVLPPF
IKEFNEILVEIPNGLSKINTLINTNLNKFNSLFYGEQSENVIDIFSLINNVVTIPDVSTIAKAIQESFKNLINIAGNLGS
GLLRLIFVLAVSLMISIEPKQYKENILLLIPKNYRNKFRNILEKCNIALANWTFSMVISSLSVGLLSLIVLSILDVKYVV
SNALIAMVLNIIPNIGPVISGIFPISIALLDNFWKPLAVLGSYVIIQNIESYIIMPSIMKKKANLLPGLTLISQFGFTFI
FGPLGLILSLPLAVVIQVLIKESFKDI

Sequences:

>Translated_347_residues
MNSLSYFKLVVILITLLIVWTLKDFLLLIICALVISNIVCNLSNQIQKGLKIPRSISLFLVLAAISVIIFTIFIIVLPPF
IKEFNEILVEIPNGLSKINTLINTNLNKFNSLFYGEQSENVIDIFSLINNVVTIPDVSTIAKAIQESFKNLINIAGNLGS
GLLRLIFVLAVSLMISIEPKQYKENILLLIPKNYRNKFRNILEKCNIALANWTFSMVISSLSVGLLSLIVLSILDVKYVV
SNALIAMVLNIIPNIGPVISGIFPISIALLDNFWKPLAVLGSYVIIQNIESYIIMPSIMKKKANLLPGLTLISQFGFTFI
FGPLGLILSLPLAVVIQVLIKESFKDI
>Mature_347_residues
MNSLSYFKLVVILITLLIVWTLKDFLLLIICALVISNIVCNLSNQIQKGLKIPRSISLFLVLAAISVIIFTIFIIVLPPF
IKEFNEILVEIPNGLSKINTLINTNLNKFNSLFYGEQSENVIDIFSLINNVVTIPDVSTIAKAIQESFKNLINIAGNLGS
GLLRLIFVLAVSLMISIEPKQYKENILLLIPKNYRNKFRNILEKCNIALANWTFSMVISSLSVGLLSLIVLSILDVKYVV
SNALIAMVLNIIPNIGPVISGIFPISIALLDNFWKPLAVLGSYVIIQNIESYIIMPSIMKKKANLLPGLTLISQFGFTFI
FGPLGLILSLPLAVVIQVLIKESFKDI

Specific function: Controls the transport of the quorum-sensing signal AI-2 either by enhancing its secretion or inhibiting its uptake and consequently represses biofilm formation and motility and affects the global gene expression in biofilms [H]

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1787885, Length=125, Percent_Identity=32.8, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 38489; Mature: 38489

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLSYFKLVVILITLLIVWTLKDFLLLIICALVISNIVCNLSNQIQKGLKIPRSISLFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VLAAISVIIFTIFIIVLPPFIKEFNEILVEIPNGLSKINTLINTNLNKFNSLFYGEQSEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCC
VIDIFSLINNVVTIPDVSTIAKAIQESFKNLINIAGNLGSGLLRLIFVLAVSLMISIEPK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHH
QYKENILLLIPKNYRNKFRNILEKCNIALANWTFSMVISSLSVGLLSLIVLSILDVKYVV
HHHCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNALIAMVLNIIPNIGPVISGIFPISIALLDNFWKPLAVLGSYVIIQNIESYIIMPSIMK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKANLLPGLTLISQFGFTFIFGPLGLILSLPLAVVIQVLIKESFKDI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSLSYFKLVVILITLLIVWTLKDFLLLIICALVISNIVCNLSNQIQKGLKIPRSISLFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VLAAISVIIFTIFIIVLPPFIKEFNEILVEIPNGLSKINTLINTNLNKFNSLFYGEQSEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCC
VIDIFSLINNVVTIPDVSTIAKAIQESFKNLINIAGNLGSGLLRLIFVLAVSLMISIEPK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHH
QYKENILLLIPKNYRNKFRNILEKCNIALANWTFSMVISSLSVGLLSLIVLSILDVKYVV
HHHCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNALIAMVLNIIPNIGPVISGIFPISIALLDNFWKPLAVLGSYVIIQNIESYIIMPSIMK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKANLLPGLTLISQFGFTFIFGPLGLILSLPLAVVIQVLIKESFKDI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]