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The map label for this gene is aspC [H]

Identifier: 126696065

GI number: 126696065

Start: 646711

End: 647889

Strand: Reverse

Name: aspC [H]

Synonym: P9301_07271

Alternate gene names: 126696065

Gene position: 647889-646711 (Counterclockwise)

Preceding gene: 126696069

Following gene: 126696064

Centisome position: 39.46

GC content: 32.57

Gene sequence:

>1179_bases
ATGAGTCAAGTTAATTTATCTGATCGGGCACTTTCAATTGAGCCATCTCTTACATTGCAGATAAGTGCTAAAGCAAATCA
ATTATCTGCAGAAGGAGTAGATATTTGCAATTTAAGTGCAGGTGAACCTGATTTTGATGCCCCAAAAGAAGTTATAGAGG
CTACAAGTAAAGCTATATTTGATGGATTTACAAAGTACGGGCCCGCAGCGGGGAATTTAGATCTCCGAAAAGCAATTGCA
AATAAACTTCAAATTCAAAACGATTTAAATTATGAATTTGAAAATGTAATGGTCACAAATGGTGCCAAGCAAGCAATATA
TAATCTTTTCCAAGTATTGTTAAATACTGGAGACGAAGTTATTATTCCTTCTCCATATTGGTTAAGTTATCCCCAGATGG
TTAGATTGGCGGGTGGGAAGCCAATTTTTACAAATTCTTCTGCAGAAGATGGATTCAAAATAAATATAGAAGATTTGAAG
TCTAAAATCTCTTCAAAAACTAAATTTATAATTATCAATTCTCCTAATAACCCCACTGGAAGAGTTATGTCAAAGGAAGA
ATTATTACAAATTGCCGATTTAGCTAGAGAAAATCCAAATATCAATATTCTTTCTGATGAGATTTACGAACTAATCCTTA
AAAAAGAATTTAAACACTACAGTTTATCTTCATTAGCAAATGACTTAAAAAATAGAATTTTTATAATAAATGGGTTTGCT
AAAGGATGGGCTATGACTGGCTGGAGGATAGGTTATTTAGTAGGCCCCAAAGATGTAATCAAAGCATCCTCAGCATTACA
AAGTCAAAGTACAAGTAATGTTTGCTCTTTTGTTCAAAAAGGTGCTTTAGAGGCTTTAAAAATTAATAATGAGTTTTTCT
CAATGATAAATAGCCATTATGATCAAAGAAGAAGAATTCTCTATGAGGGCCTTAACAATATAAATGGGATTTATATTGAA
GAACCTAATGGAGCATTTTACGCATTTCCAAAATTACCCAACTCCTCAATTACTTCTGTTGATTTCTGCAATAAAGCTCT
TCAAGATTACGGATTAGTTGTTGTACCTGGAAAAGCTTTTGGAGCTGATCAATGTATAAGAATATCTTGTGCAGCTTCAG
AAATTAAAATAAAAGATGGACTTCAGAGGATTGAAAAAGCAATCTCTGAATACTATTAA

Upstream 100 bases:

>100_bases
AAGAAAATGAACTAAATTAAACCATAGTGTGATAGTTTTATTTATTCTTAATTTATGCATTTGTCATTATTAAAAGTCAT
ATTTGAAAAGTCATAAGTCA

Downstream 100 bases:

>100_bases
TTTAACTAAGTTATGTTTAATTTAAAGTATTTCCTTGTAAGTTCATCTCTATTATTTTCTGTTTTTTCATCACCTGTATT
TTCAAATCCCAAAGTTTTAA

Product: aminotransferases class-I

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSQVNLSDRALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFDAPKEVIEATSKAIFDGFTKYGPAAGNLDLRKAIA
NKLQIQNDLNYEFENVMVTNGAKQAIYNLFQVLLNTGDEVIIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKINIEDLK
SKISSKTKFIIINSPNNPTGRVMSKEELLQIADLARENPNINILSDEIYELILKKEFKHYSLSSLANDLKNRIFIINGFA
KGWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHYDQRRRILYEGLNNINGIYIE
EPNGAFYAFPKLPNSSITSVDFCNKALQDYGLVVVPGKAFGADQCIRISCAASEIKIKDGLQRIEKAISEYY

Sequences:

>Translated_392_residues
MSQVNLSDRALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFDAPKEVIEATSKAIFDGFTKYGPAAGNLDLRKAIA
NKLQIQNDLNYEFENVMVTNGAKQAIYNLFQVLLNTGDEVIIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKINIEDLK
SKISSKTKFIIINSPNNPTGRVMSKEELLQIADLARENPNINILSDEIYELILKKEFKHYSLSSLANDLKNRIFIINGFA
KGWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHYDQRRRILYEGLNNINGIYIE
EPNGAFYAFPKLPNSSITSVDFCNKALQDYGLVVVPGKAFGADQCIRISCAASEIKIKDGLQRIEKAISEYY
>Mature_391_residues
SQVNLSDRALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFDAPKEVIEATSKAIFDGFTKYGPAAGNLDLRKAIAN
KLQIQNDLNYEFENVMVTNGAKQAIYNLFQVLLNTGDEVIIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKINIEDLKS
KISSKTKFIIINSPNNPTGRVMSKEELLQIADLARENPNINILSDEIYELILKKEFKHYSLSSLANDLKNRIFIINGFAK
GWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHYDQRRRILYEGLNNINGIYIEE
PNGAFYAFPKLPNSSITSVDFCNKALQDYGLVVVPGKAFGADQCIRISCAASEIKIKDGLQRIEKAISEYY

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=391, Percent_Identity=25.8312020460358, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI169881279, Length=391, Percent_Identity=25.8312020460358, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI56713254, Length=314, Percent_Identity=30.5732484076433, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI56713256, Length=314, Percent_Identity=30.5732484076433, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=27.3209549071618, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI169881281, Length=319, Percent_Identity=23.5109717868339, Blast_Score=105, Evalue=7e-23,
Organism=Escherichia coli, GI1788627, Length=320, Percent_Identity=32.5, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1786816, Length=377, Percent_Identity=28.6472148541114, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=26.1096605744125, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1790797, Length=381, Percent_Identity=23.3595800524934, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI48994949, Length=374, Percent_Identity=23.7967914438503, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=344, Percent_Identity=28.1976744186047, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71994476, Length=283, Percent_Identity=30.3886925795053, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=283, Percent_Identity=30.3886925795053, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=326, Percent_Identity=29.4478527607362, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322401, Length=400, Percent_Identity=24.75, Blast_Score=119, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6323118, Length=340, Percent_Identity=22.9411764705882, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=311, Percent_Identity=24.7588424437299, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573069, Length=349, Percent_Identity=26.3610315186246, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646114, Length=349, Percent_Identity=26.3610315186246, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573067, Length=349, Percent_Identity=26.3610315186246, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573065, Length=349, Percent_Identity=26.3610315186246, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=22.0159151193634, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43430; Mature: 43299

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVNLSDRALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFDAPKEVIEATSKAIF
CCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
DGFTKYGPAAGNLDLRKAIANKLQIQNDLNYEFENVMVTNGAKQAIYNLFQVLLNTGDEV
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECEEEEECCHHHHHHHHHHHHHCCCCCE
IIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKINIEDLKSKISSKTKFIIINSPNNPTG
EECCCCCCCCHHHHHHCCCCEEECCCCCCCCEEEEHHHHHHHHCCCEEEEEEECCCCCCC
RVMSKEELLQIADLARENPNINILSDEIYELILKKEFKHYSLSSLANDLKNRIFIINGFA
CCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
KGWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHY
CCEECCCEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEEECHHHHHHHHHHH
DQRRRILYEGLNNINGIYIEEPNGAFYAFPKLPNSSITSVDFCNKALQDYGLVVVPGKAF
HHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHCCEEEECCCCC
GADQCIRISCAASEIKIKDGLQRIEKAISEYY
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQVNLSDRALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFDAPKEVIEATSKAIF
CCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
DGFTKYGPAAGNLDLRKAIANKLQIQNDLNYEFENVMVTNGAKQAIYNLFQVLLNTGDEV
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECEEEEECCHHHHHHHHHHHHHCCCCCE
IIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKINIEDLKSKISSKTKFIIINSPNNPTG
EECCCCCCCCHHHHHHCCCCEEECCCCCCCCEEEEHHHHHHHHCCCEEEEEEECCCCCCC
RVMSKEELLQIADLARENPNINILSDEIYELILKKEFKHYSLSSLANDLKNRIFIINGFA
CCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
KGWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHY
CCEECCCEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEEECHHHHHHHHHHH
DQRRRILYEGLNNINGIYIEEPNGAFYAFPKLPNSSITSVDFCNKALQDYGLVVVPGKAF
HHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHCCEEEECCCCC
GADQCIRISCAASEIKIKDGLQRIEKAISEYY
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]