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The map label for this gene is sds [H]

Identifier: 126695982

GI number: 126695982

Start: 572995

End: 573966

Strand: Direct

Name: sds [H]

Synonym: P9301_06441

Alternate gene names: 126695982

Gene position: 572995-573966 (Clockwise)

Preceding gene: 126695981

Following gene: 126695983

Centisome position: 34.9

GC content: 35.08

Gene sequence:

>972_bases
ATGAATACAGTAACAGAGCTACTACAACCAGTTGAAAATGATCTTGATGATCTTATTCTTGAACTGAAAAATCTAATAGG
AGCTGGTCATCCAATTCTTCAAGCAGCAGCGGAACATCTATTTAGCGCTGGAGGAAAAAGACTGAGGCCGGGAATTGTTC
TGTTAATTTCAAAAGCTATATCTCCGGAATTTTGCTTGACAACCAAACATAAAAGGCTTGCTGAAATAACTGAGATGATT
CATACAGCCTCATTAGTCCATGATGATGTTGTTGATGAGGCGTCTACAAGAAGAGGAGTAGATACAGTTCATAGTAGATT
TAATACCAGAGTAGCTGTTTTGGCGGGTGACTTTTTATTTGCTCAAGCTAGTTGGCACCTAGCAAATCTTGACAATGTAA
ATGTAGTTAAATTACTTAGTAGAGTAATAATGGATTTAGCAGAAGGCGAAATTAAACAAAACTTAAATAGATTTGATTCA
GCTCAATCTTTTCCCAAATACATCAATAAAAGTTATTGTAAAACAGCATCATTAATAGCAAATAGTTGCAAAGCAGCTGG
AGTTTTGAGTGGGATTAATGACGAAAACTTAACCTCGCTTTACGATTTTGGCAAAAATATTGGTTTAGCATTCCAAGTTG
TAGATGACATTCTTGACTTTACTGGAAATGATAAACAACTTGGAAAACCTGCTGTAAGTGATCTTGCTAGTGGTTATCTT
ACCGCCCCAGTTTTATATGCCTTAGAAGAAAATAAACAATTGTCAGTTCTTATAAACAGAGAACTTGCTGAAAAAGATGA
TTTAGATAATGCTCTTAATATCATAATGAACTCTAAAGCTATTGAAAGTTCAAGAAAACTAGCTGAGGATTTTGCAATGC
TCTCTAAAGAGGCTATAGTCTGGCTTCCTGATTCAGAATATAAAAGAGCTTTAATGGCTCTTCCAGAATTTGTTCTAAGC
CGCATTTATTAG

Upstream 100 bases:

>100_bases
TTCCAATAAAGTAAAATTTTGGCTTGGAATTAATAAAGAAATTAGGGTTGTTAACCTCCGAAGTAATGTTTGATTCCTTA
ATATATAAGAGAGGTCAATC

Downstream 100 bases:

>100_bases
ATCTATTAGAAATAAATCTTTGAGCTAAATTAATATTAAAATTTTTGATAACCTTAATCTTTTCGACTAAATTTATTAAG
CATAGATTTATTTAATGACA

Product: polyprenyl synthetase; solanesyl diphosphate synthase (sds)

Products: diphosphate; all-trans-nonaprenyl diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MNTVTELLQPVENDLDDLILELKNLIGAGHPILQAAAEHLFSAGGKRLRPGIVLLISKAISPEFCLTTKHKRLAEITEMI
HTASLVHDDVVDEASTRRGVDTVHSRFNTRVAVLAGDFLFAQASWHLANLDNVNVVKLLSRVIMDLAEGEIKQNLNRFDS
AQSFPKYINKSYCKTASLIANSCKAAGVLSGINDENLTSLYDFGKNIGLAFQVVDDILDFTGNDKQLGKPAVSDLASGYL
TAPVLYALEENKQLSVLINRELAEKDDLDNALNIIMNSKAIESSRKLAEDFAMLSKEAIVWLPDSEYKRALMALPEFVLS
RIY

Sequences:

>Translated_323_residues
MNTVTELLQPVENDLDDLILELKNLIGAGHPILQAAAEHLFSAGGKRLRPGIVLLISKAISPEFCLTTKHKRLAEITEMI
HTASLVHDDVVDEASTRRGVDTVHSRFNTRVAVLAGDFLFAQASWHLANLDNVNVVKLLSRVIMDLAEGEIKQNLNRFDS
AQSFPKYINKSYCKTASLIANSCKAAGVLSGINDENLTSLYDFGKNIGLAFQVVDDILDFTGNDKQLGKPAVSDLASGYL
TAPVLYALEENKQLSVLINRELAEKDDLDNALNIIMNSKAIESSRKLAEDFAMLSKEAIVWLPDSEYKRALMALPEFVLS
RIY
>Mature_323_residues
MNTVTELLQPVENDLDDLILELKNLIGAGHPILQAAAEHLFSAGGKRLRPGIVLLISKAISPEFCLTTKHKRLAEITEMI
HTASLVHDDVVDEASTRRGVDTVHSRFNTRVAVLAGDFLFAQASWHLANLDNVNVVKLLSRVIMDLAEGEIKQNLNRFDS
AQSFPKYINKSYCKTASLIANSCKAAGVLSGINDENLTSLYDFGKNIGLAFQVVDDILDFTGNDKQLGKPAVSDLASGYL
TAPVLYALEENKQLSVLINRELAEKDDLDNALNIIMNSKAIESSRKLAEDFAMLSKEAIVWLPDSEYKRALMALPEFVLS
RIY

Specific function: Possible role in synthesis of the nonaprenyl side chain of plastoquinone or in synthesis of other prenyl chains such as undekaprenyl pyrophosphate [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=294, Percent_Identity=39.7959183673469, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI169808399, Length=324, Percent_Identity=29.320987654321, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI4758430, Length=224, Percent_Identity=25.4464285714286, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI83700220, Length=224, Percent_Identity=25.4464285714286, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1789578, Length=287, Percent_Identity=33.4494773519164, Blast_Score=172, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17505681, Length=293, Percent_Identity=35.8361774744027, Blast_Score=188, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6319475, Length=298, Percent_Identity=37.9194630872483, Blast_Score=193, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24651612, Length=312, Percent_Identity=36.5384615384615, Blast_Score=211, Evalue=4e-55,
Organism=Drosophila melanogaster, GI21356309, Length=355, Percent_Identity=25.9154929577465, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR014120
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: 2.5.1.11

Molecular weight: Translated: 35615; Mature: 35615

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVTELLQPVENDLDDLILELKNLIGAGHPILQAAAEHLFSAGGKRLRPGIVLLISKAI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
SPEFCLTTKHKRLAEITEMIHTASLVHDDVVDEASTRRGVDTVHSRFNTRVAVLAGDFLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEEECHHHH
AQASWHLANLDNVNVVKLLSRVIMDLAEGEIKQNLNRFDSAQSFPKYINKSYCKTASLIA
HHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSCKAAGVLSGINDENLTSLYDFGKNIGLAFQVVDDILDFTGNDKQLGKPAVSDLASGYL
HHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCHH
TAPVLYALEENKQLSVLINRELAEKDDLDNALNIIMNSKAIESSRKLAEDFAMLSKEAIV
HHHHHHHHHCCCEEEEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
WLPDSEYKRALMALPEFVLSRIY
ECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTVTELLQPVENDLDDLILELKNLIGAGHPILQAAAEHLFSAGGKRLRPGIVLLISKAI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
SPEFCLTTKHKRLAEITEMIHTASLVHDDVVDEASTRRGVDTVHSRFNTRVAVLAGDFLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEEECHHHH
AQASWHLANLDNVNVVKLLSRVIMDLAEGEIKQNLNRFDSAQSFPKYINKSYCKTASLIA
HHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSCKAAGVLSGINDENLTSLYDFGKNIGLAFQVVDDILDFTGNDKQLGKPAVSDLASGYL
HHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCHH
TAPVLYALEENKQLSVLINRELAEKDDLDNALNIIMNSKAIESSRKLAEDFAMLSKEAIV
HHHHHHHHHCCCEEEEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
WLPDSEYKRALMALPEFVLSRIY
ECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: all-trans-octaprenyl diphosphate; isopentenyl diphosphate

Specific reaction: all-trans-octaprenyl diphosphate + isopentenyl diphosphate = diphosphate + all-trans-nonaprenyl diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]