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The map label for this gene is trpF [H]

Identifier: 126695901

GI number: 126695901

Start: 492590

End: 493246

Strand: Reverse

Name: trpF [H]

Synonym: P9301_05631

Alternate gene names: 126695901

Gene position: 493246-492590 (Counterclockwise)

Preceding gene: 126695903

Following gene: 126695894

Centisome position: 30.04

GC content: 30.29

Gene sequence:

>657_bases
ATGCCCAAGACTAATCCTTTAGTTAAAATTTGTGGACTAACTTCTGAAGAACAAGCTCTTCAAGTCGCCAAATTAGGAGC
GAATGCTATTGGCATTATTTCGGTTGAAGAATCTCCAAGGTATGTATCAGCTGAAATTAAGAAAAAAATATTTAAAACCC
TAGAAAATTTTTATCCAAAAATCGATAGAGTAACTGTTGTGCAAAATTGTCCGATAGATTTAATTATCAAAAACTTCTTA
GGCAAACCAAGCGAAACTATCATTCAATTACATGGAGATGAAGATATTGATTATTGCAAAAAAATAAGGAAATACATTCC
AAATATAGGCCTATGGAAGGCTTTCAGAATAAAAACGGAAGAGGACATAGATAAAATAAAACCTTTTGAAGATTTTATAG
ATGCGATACTACTTGATTCTTGGAATAAAGAAACTTATGGAGGTTCAGGGAAAAAAATAAATTCTATTTATCTAAAGAAT
CTGCAATTCAACAAACCATGGTGGTTAGCAGGTGGAATATCAATTGAATGGATTGATGAAATCCTTACTGAAATCAAACC
AGATGGACTAGATATTTCAAGTAGTATTGAAATATCCCCCGGTTATAAAGATATTAAAAAAACAGAAAATATTTTTAAGT
TTTTAAAAGGAATTTAA

Upstream 100 bases:

>100_bases
TTTAAAGGGAATTCCCCATATTTTAAAAATTTGCCAACTTCTCAAAAATAATCTCCGCTATATTTAGCAATAATATTAAT
CTTACATGCAGGATAATGAT

Downstream 100 bases:

>100_bases
TAATTATTAGTAGCGGACTGTTGTTTTACAAGCTCAAAAAATTCTTGTTTTAAACTTAAATCGTGTCTAAAATCGCCTCT
AACAACAGAATTAATCATGC

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MPKTNPLVKICGLTSEEQALQVAKLGANAIGIISVEESPRYVSAEIKKKIFKTLENFYPKIDRVTVVQNCPIDLIIKNFL
GKPSETIIQLHGDEDIDYCKKIRKYIPNIGLWKAFRIKTEEDIDKIKPFEDFIDAILLDSWNKETYGGSGKKINSIYLKN
LQFNKPWWLAGGISIEWIDEILTEIKPDGLDISSSIEISPGYKDIKKTENIFKFLKGI

Sequences:

>Translated_218_residues
MPKTNPLVKICGLTSEEQALQVAKLGANAIGIISVEESPRYVSAEIKKKIFKTLENFYPKIDRVTVVQNCPIDLIIKNFL
GKPSETIIQLHGDEDIDYCKKIRKYIPNIGLWKAFRIKTEEDIDKIKPFEDFIDAILLDSWNKETYGGSGKKINSIYLKN
LQFNKPWWLAGGISIEWIDEILTEIKPDGLDISSSIEISPGYKDIKKTENIFKFLKGI
>Mature_217_residues
PKTNPLVKICGLTSEEQALQVAKLGANAIGIISVEESPRYVSAEIKKKIFKTLENFYPKIDRVTVVQNCPIDLIIKNFLG
KPSETIIQLHGDEDIDYCKKIRKYIPNIGLWKAFRIKTEEDIDKIKPFEDFIDAILLDSWNKETYGGSGKKINSIYLKNL
QFNKPWWLAGGISIEWIDEILTEIKPDGLDISSSIEISPGYKDIKKTENIFKFLKGI

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=213, Percent_Identity=29.1079812206573, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 24852; Mature: 24721

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTNPLVKICGLTSEEQALQVAKLGANAIGIISVEESPRYVSAEIKKKIFKTLENFYPK
CCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
IDRVTVVQNCPIDLIIKNFLGKPSETIIQLHGDEDIDYCKKIRKYIPNIGLWKAFRIKTE
CCEEEEECCCCHHHHHHHHCCCCCHHEEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCH
EDIDKIKPFEDFIDAILLDSWNKETYGGSGKKINSIYLKNLQFNKPWWLAGGISIEWIDE
HHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEHHEEEECCCCCCCEEEECCCHHHHHHH
ILTEIKPDGLDISSSIEISPGYKDIKKTENIFKFLKGI
HHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKTNPLVKICGLTSEEQALQVAKLGANAIGIISVEESPRYVSAEIKKKIFKTLENFYPK
CCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
IDRVTVVQNCPIDLIIKNFLGKPSETIIQLHGDEDIDYCKKIRKYIPNIGLWKAFRIKTE
CCEEEEECCCCHHHHHHHHCCCCCHHEEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCH
EDIDKIKPFEDFIDAILLDSWNKETYGGSGKKINSIYLKNLQFNKPWWLAGGISIEWIDE
HHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEHHEEEECCCCCCCEEEECCCHHHHHHH
ILTEIKPDGLDISSSIEISPGYKDIKKTENIFKFLKGI
HHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA