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The map label for this gene is agaR [H]

Identifier: 262192861

GI number: 262192861

Start: 1194208

End: 1195032

Strand: Direct

Name: agaR [H]

Synonym: BMA10247_A1228

Alternate gene names: 262192861

Gene position: 1194208-1195032 (Clockwise)

Preceding gene: 126445879

Following gene: 126447623

Centisome position: 50.76

GC content: 72.24

Gene sequence:

>825_bases
ATGCACGTTTCAATTCTTGTTCATGCACGTTATACTGCGCGCATGAACGATGCCATTCCACTTGCACGACGCGACGCAAT
CGCCGGCCGGCTCGCCCTCGGGCAGCCGGTGCAAGCCGCCGCGCTCGCCGCCGAATTCCATGTCTCCGAAGACGCGATCC
GGCGCGATCTGCGCGCGCTCGCCGCCGAGGGCCGCTGCCGCCGCGTCTACGGCGGCGCGCTGCCCGTCACGCCGGCGTGC
GCGCCGATGGCGGCCCGCATCGACGCGGCACGCGAGCGCAAGGCGGCGCTCGCGCGCACGGCCGCATCGCTGATCGAGCG
CGGCGAGCTGCTGTTCCTCGATAGCGGCAGCACCGCTCTCGCGCTCGTCGAATATCTGCCCGAGGACGCCGAGCTCACCA
TCGCGACCAATTCGATCGACATCGCCGCGGCGGTGCTGCGGCGCGCCGACCTGAGCCTCATCATGATCGGCGGCGCGGTC
GACCAGGCGGTCGGCGGCTGCGTCGACGCATCCGCCGTGCAAAGCGTCGCGCGCATGAACATCGACCGCGGTTTCCTCGG
CGCGTGCGCGCTGTCGCCGCAACGCGGCCTCGCCGCATTCGGCCTCGCCGACGCGACGTTCAAGCGCGCCGTCGTCGCCG
CGAGCGCGCGCTGCGTCGTGCTCGCGACCACCGACAAGCTCGCCGCGCGCGCGCCCCACCGGGTTGCCGCGCTCGACGAG
ATCGACTGCATCGTCGTCGAGCACGATCTGCCGCGCGAGGACCGCGCGGCGCTGTCGAGCGCCGGCGCGTCGATCCTCGC
GGCGAACCCGCCCGCGCAGCCGTAA

Upstream 100 bases:

>100_bases
GCCCGCCTTGTCGCGGTCGAAACGGTTCGTCGTGGGCAGCGGCGCGCGGCGTTGCGATAACGGCGCCCCTTTCCGTAGGC
CTCGCACGAAATGCACGTTT

Downstream 100 bases:

>100_bases
CGCCCGCCCGTCATGCCTACGGAGCTCATCGACATGTCTTCCGATCGGCCGGCTACCCGGCTTGCCACCCGTCTCGCCTT
TCTCGTCGCGGGCTTCGGCG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MHVSILVHARYTARMNDAIPLARRDAIAGRLALGQPVQAAALAAEFHVSEDAIRRDLRALAAEGRCRRVYGGALPVTPAC
APMAARIDAARERKAALARTAASLIERGELLFLDSGSTALALVEYLPEDAELTIATNSIDIAAAVLRRADLSLIMIGGAV
DQAVGGCVDASAVQSVARMNIDRGFLGACALSPQRGLAAFGLADATFKRAVVAASARCVVLATTDKLAARAPHRVAALDE
IDCIVVEHDLPREDRAALSSAGASILAANPPAQP

Sequences:

>Translated_274_residues
MHVSILVHARYTARMNDAIPLARRDAIAGRLALGQPVQAAALAAEFHVSEDAIRRDLRALAAEGRCRRVYGGALPVTPAC
APMAARIDAARERKAALARTAASLIERGELLFLDSGSTALALVEYLPEDAELTIATNSIDIAAAVLRRADLSLIMIGGAV
DQAVGGCVDASAVQSVARMNIDRGFLGACALSPQRGLAAFGLADATFKRAVVAASARCVVLATTDKLAARAPHRVAALDE
IDCIVVEHDLPREDRAALSSAGASILAANPPAQP
>Mature_274_residues
MHVSILVHARYTARMNDAIPLARRDAIAGRLALGQPVQAAALAAEFHVSEDAIRRDLRALAAEGRCRRVYGGALPVTPAC
APMAARIDAARERKAALARTAASLIERGELLFLDSGSTALALVEYLPEDAELTIATNSIDIAAAVLRRADLSLIMIGGAV
DQAVGGCVDASAVQSVARMNIDRGFLGACALSPQRGLAAFGLADATFKRAVVAASARCVVLATTDKLAARAPHRVAALDE
IDCIVVEHDLPREDRAALSSAGASILAANPPAQP

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=248, Percent_Identity=28.6290322580645, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI226510968, Length=253, Percent_Identity=32.4110671936759, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789829, Length=239, Percent_Identity=26.3598326359833, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789170, Length=228, Percent_Identity=27.1929824561404, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789059, Length=249, Percent_Identity=24.8995983935743, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788069, Length=228, Percent_Identity=25.8771929824561, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=25.7510729613734, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790753, Length=177, Percent_Identity=28.8135593220339, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790635, Length=221, Percent_Identity=23.5294117647059, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28483; Mature: 28483

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVSILVHARYTARMNDAIPLARRDAIAGRLALGQPVQAAALAAEFHVSEDAIRRDLRAL
CEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
AAEGRCRRVYGGALPVTPACAPMAARIDAARERKAALARTAASLIERGELLFLDSGSTAL
HHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHH
ALVEYLPEDAELTIATNSIDIAAAVLRRADLSLIMIGGAVDQAVGGCVDASAVQSVARMN
HHHHHCCCCCEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHCCCCCHHHHHHHHHHC
IDRGFLGACALSPQRGLAAFGLADATFKRAVVAASARCVVLATTDKLAARAPHRVAALDE
CCCCCHHHEECCCCCCCCHHCCHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCEEECCC
IDCIVVEHDLPREDRAALSSAGASILAANPPAQP
CEEEEEECCCCCHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MHVSILVHARYTARMNDAIPLARRDAIAGRLALGQPVQAAALAAEFHVSEDAIRRDLRAL
CEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
AAEGRCRRVYGGALPVTPACAPMAARIDAARERKAALARTAASLIERGELLFLDSGSTAL
HHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHH
ALVEYLPEDAELTIATNSIDIAAAVLRRADLSLIMIGGAVDQAVGGCVDASAVQSVARMN
HHHHHCCCCCEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHCCCCCHHHHHHHHHHC
IDRGFLGACALSPQRGLAAFGLADATFKRAVVAASARCVVLATTDKLAARAPHRVAALDE
CCCCCHHHEECCCCCCCCHHCCHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCEEECCC
IDCIVVEHDLPREDRAALSSAGASILAANPPAQP
CEEEEEECCCCCHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]