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The map label for this gene is shiA [H]

Identifier: 126447856

GI number: 126447856

Start: 1229767

End: 1231086

Strand: Reverse

Name: shiA [H]

Synonym: BMA10247_A1267

Alternate gene names: 126447856

Gene position: 1231086-1229767 (Counterclockwise)

Preceding gene: 126445711

Following gene: 126445980

Centisome position: 52.33

GC content: 69.7

Gene sequence:

>1320_bases
TTGACCCGGGGCATCCCACCGAGCCCGCCGGCGCGCCAGCCGCGCCGCGCGGCCGGCGCCGCGTTCGTCGGCACGATGAT
CGAGTGGTACGACTTCTACATCTACGCGAACGCGGCCGCGCTCGTCTTCGGCGAGCTGTTCTTCCCGTCGCACGATCCGT
TCACGAGCACGATGGCGTCGTTCGCGACGTTCGCGGTCGGCTTCTTCGCGCGCCCGCTCGGCGGGCTCTTCTTCGGCCAT
CTCGGCGACCGGATCGGCCGCAAGAAGGCGCTGATGGCGACGCTCGCGCTGATGGGCGCGGCGACGGTCTGCGTCGGTCT
GCTGCCGACCTACGAACGCGTCGGCCTGCTCGCGCCCGTGCTGCTCGTGCTGCTGCGCATCGTTCAGGGCATCGCGGTGG
GCGGCGAGTGGGGCGGCGCGGTGCTGATGGCGGGCGAGCATGCGCCGTATGGGCGGCGCACGTTCTTCGCTTCGTTCGCG
CAGTTGGGCAGCCCGGCCGGGCTGATCCTGTCGCTCGTCGCGTTTCGCGCGGTCGCGTCGATGGAGCACGGCGCGTTCAT
GTCCTGGGGCTGGCGGCTGCCGTTTCTCGCGAGCATCGCGCTGCTCGCGGTCGGCGTGTTCGTGCGGCTGAAGGTCGACG
AATCGCCCGAGTTCGCGCATGAGAAGGCGATGTCGCGCACCGTCGCGCGGCCGCTCGCCGAGGCGCTGCGCACGTCGCGC
GCGATGCTGCTGTTCTGCCTGTGCGCGAACACGATCGGTATCGCGGGGCTGTATTTCACGAACACGTTCATGATCGCGTT
CACGACGCAGCATGTGGGCGTGACGAAATCGCTGATCCTCGATTGCCTGTTCATCGTCGCGATCATCCAGTTCGTGACGC
AGCCGATCGCCGCGTGGCTCGGCGGCAAGCTCGGCGACGCACGCTTTCTCAAGCTCGCCGCGCTGTTCGCGATGGCCTCG
CCCTATCCGATGTTCGCGCTCGTGCAGACGGGGCGGCTCGCGCCGATGGTGATCGGCATCGCGATCGCGACCGTGTTTCT
CGCCGGTTTCTACTCGGTGATCGCGGGCTTCGTGAGCGGCGCGTTCCCGACGCGCGTGCGCTATTCGGCGATCTCGATCT
CGTACCAGATGTGCGGCGCGATCGCGGGCGGGCTGACGCCGCTCGTCGGCACGTGGCTCGCGCACCGGTTCGCCGGGCAG
TGGTGGCCGCTCGCGGTGTTCTATACGTGCCTCGCGGCGCTCTCGCTCGGCGGCGTGATCGCGCTCGACGCGCGCCGCCA
TCGGCGGGCCGACGTCGCCGACGCCGTGCTCACGCGCTGA

Upstream 100 bases:

>100_bases
ACTTAGAATTTGACCGATTAATCCCGGTGCGCGATAAAACGCCCATTTGCCGAATCCGGACGATTCGGCCGGGGCGGACA
TTCGAGTGAGGAGAAACGCA

Downstream 100 bases:

>100_bases
TTCAAGAAAAGGAGGGAGATCTCGGTGTGGGAAATTGACGGTAGGCGGCTCTGGAACAGCCTGACGGAACTCGCGCGAAT
CGGCGGCACCGCGCGCGGCG

Product: major facilitator family transporter

Products: Proton [Cytoplasm]; shikimate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MTRGIPPSPPARQPRRAAGAAFVGTMIEWYDFYIYANAAALVFGELFFPSHDPFTSTMASFATFAVGFFARPLGGLFFGH
LGDRIGRKKALMATLALMGAATVCVGLLPTYERVGLLAPVLLVLLRIVQGIAVGGEWGGAVLMAGEHAPYGRRTFFASFA
QLGSPAGLILSLVAFRAVASMEHGAFMSWGWRLPFLASIALLAVGVFVRLKVDESPEFAHEKAMSRTVARPLAEALRTSR
AMLLFCLCANTIGIAGLYFTNTFMIAFTTQHVGVTKSLILDCLFIVAIIQFVTQPIAAWLGGKLGDARFLKLAALFAMAS
PYPMFALVQTGRLAPMVIGIAIATVFLAGFYSVIAGFVSGAFPTRVRYSAISISYQMCGAIAGGLTPLVGTWLAHRFAGQ
WWPLAVFYTCLAALSLGGVIALDARRHRRADVADAVLTR

Sequences:

>Translated_439_residues
MTRGIPPSPPARQPRRAAGAAFVGTMIEWYDFYIYANAAALVFGELFFPSHDPFTSTMASFATFAVGFFARPLGGLFFGH
LGDRIGRKKALMATLALMGAATVCVGLLPTYERVGLLAPVLLVLLRIVQGIAVGGEWGGAVLMAGEHAPYGRRTFFASFA
QLGSPAGLILSLVAFRAVASMEHGAFMSWGWRLPFLASIALLAVGVFVRLKVDESPEFAHEKAMSRTVARPLAEALRTSR
AMLLFCLCANTIGIAGLYFTNTFMIAFTTQHVGVTKSLILDCLFIVAIIQFVTQPIAAWLGGKLGDARFLKLAALFAMAS
PYPMFALVQTGRLAPMVIGIAIATVFLAGFYSVIAGFVSGAFPTRVRYSAISISYQMCGAIAGGLTPLVGTWLAHRFAGQ
WWPLAVFYTCLAALSLGGVIALDARRHRRADVADAVLTR
>Mature_438_residues
TRGIPPSPPARQPRRAAGAAFVGTMIEWYDFYIYANAAALVFGELFFPSHDPFTSTMASFATFAVGFFARPLGGLFFGHL
GDRIGRKKALMATLALMGAATVCVGLLPTYERVGLLAPVLLVLLRIVQGIAVGGEWGGAVLMAGEHAPYGRRTFFASFAQ
LGSPAGLILSLVAFRAVASMEHGAFMSWGWRLPFLASIALLAVGVFVRLKVDESPEFAHEKAMSRTVARPLAEALRTSRA
MLLFCLCANTIGIAGLYFTNTFMIAFTTQHVGVTKSLILDCLFIVAIIQFVTQPIAAWLGGKLGDARFLKLAALFAMASP
YPMFALVQTGRLAPMVIGIAIATVFLAGFYSVIAGFVSGAFPTRVRYSAISISYQMCGAIAGGLTPLVGTWLAHRFAGQW
WPLAVFYTCLAALSLGGVIALDARRHRRADVADAVLTR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788292, Length=423, Percent_Identity=36.4066193853428, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1790550, Length=393, Percent_Identity=32.0610687022901, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1789941, Length=429, Percent_Identity=33.7995337995338, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1788942, Length=383, Percent_Identity=30.2872062663185, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI87082231, Length=439, Percent_Identity=22.0956719817768, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082404, Length=392, Percent_Identity=20.9183673469388, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 47024; Mature: 46893

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRGIPPSPPARQPRRAAGAAFVGTMIEWYDFYIYANAAALVFGELFFPSHDPFTSTMAS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
FATFAVGFFARPLGGLFFGHLGDRIGRKKALMATLALMGAATVCVGLLPTYERVGLLAPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LLVLLRIVQGIAVGGEWGGAVLMAGEHAPYGRRTFFASFAQLGSPAGLILSLVAFRAVAS
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MEHGAFMSWGWRLPFLASIALLAVGVFVRLKVDESPEFAHEKAMSRTVARPLAEALRTSR
HCCCCHHCCCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
AMLLFCLCANTIGIAGLYFTNTFMIAFTTQHVGVTKSLILDCLFIVAIIQFVTQPIAAWL
HHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGKLGDARFLKLAALFAMASPYPMFALVQTGRLAPMVIGIAIATVFLAGFYSVIAGFVSG
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFPTRVRYSAISISYQMCGAIAGGLTPLVGTWLAHRFAGQWWPLAVFYTCLAALSLGGVI
CCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEE
ALDARRHRRADVADAVLTR
EECCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRGIPPSPPARQPRRAAGAAFVGTMIEWYDFYIYANAAALVFGELFFPSHDPFTSTMAS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
FATFAVGFFARPLGGLFFGHLGDRIGRKKALMATLALMGAATVCVGLLPTYERVGLLAPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LLVLLRIVQGIAVGGEWGGAVLMAGEHAPYGRRTFFASFAQLGSPAGLILSLVAFRAVAS
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MEHGAFMSWGWRLPFLASIALLAVGVFVRLKVDESPEFAHEKAMSRTVARPLAEALRTSR
HCCCCHHCCCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
AMLLFCLCANTIGIAGLYFTNTFMIAFTTQHVGVTKSLILDCLFIVAIIQFVTQPIAAWL
HHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGKLGDARFLKLAALFAMASPYPMFALVQTGRLAPMVIGIAIATVFLAGFYSVIAGFVSG
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFPTRVRYSAISISYQMCGAIAGGLTPLVGTWLAHRFAGQWWPLAVFYTCLAALSLGGVI
CCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEE
ALDARRHRRADVADAVLTR
EECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; shikimate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + shikimate [Periplasm] = Proton [Cytoplasm] + shikimate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9524262; 9097040; 9278503 [H]