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The map label for this gene is exuT [H]

Identifier: 126447435

GI number: 126447435

Start: 2266180

End: 2267505

Strand: Direct

Name: exuT [H]

Synonym: BMA10247_A2335

Alternate gene names: 126447435

Gene position: 2266180-2267505 (Clockwise)

Preceding gene: 126446972

Following gene: 126446581

Centisome position: 96.32

GC content: 71.95

Gene sequence:

>1326_bases
TTGCATATTCATCCAGCCGACGTCGACGACGGCGCGCTCGCCGCGCCCATTCCCCGTCCGTATGCGTGGACCGTGTTCGC
GCTCGCGTTCGCGCTGCTGCTGTCCGACTACATGTCGCGGCAGGTGCTCAACGCCGTGTTTCCGCTGCTCAAGGCCGCGT
GGGGCCTGTCCGACACGCGGCTCGGCTCGTTGAGCGGCATCGTCGCGCTGATGGTCGGCACGCTGACATTTCCGCTGTCG
GTGCTCGCCGACCGCTGGGGCCGCGTGCGCAGCATCACGCTGATGGCGGCGCTCTGGAGCGTCGCGACGCTCGGCTGCGC
GGCCGCGACGAGCTACGGCGAGTTGCTCGTCGCGCGCGCGTTCGTCGGCGTCGGCGAGGCCGCGTACGGCAGCGTCGGCG
TCGCGCTGATCCTCGGCCTCTTCCCGCCGCATCTGCGCTCGACGCTCACCGGCGCGTTCATGGCGGGCGGCGCGTTCGGC
TCGGTGCTCGGCATGGCACTGGGCGGCGCCGTCGCGACGCAGCTCGGCTGGCGCGCTTCGTTCGGCGCGATGGCGTGCCT
CGGCTTCGCGCTCGTCGTCTGCTTTCGGCTCGTCGTGACCGAGCGGCGCATCGCGGGCAACGGCGCGCGCGCGGCGCGCT
CGGGCCGCGAACGCGCGCCGGCACTGGCGCATGCGAGCTTGCGCACGGTGCTCGCCGAGCTGTTCTCGACGGTGTCGGTC
GTCTGCGCATATGTCGGCAGCGGGTTGCAGCTCTTCATCATGGGCGCGGTGATCGCATGGATGCCGAGCTTCCTCAATCG
CTACTACGCGCTGCCGCCCGACAAGGCCGCGGCCGCGGCCGCGGGATTCGTGCTGCTCGGCGGCTCGGGCATGATCGCGT
GCGGCATCGTCACGGACCGGCTGAGCCGTGCGTGCCCAGAGCGCAAGTGGGCAATGGCGATCGTGTACTGCGCGATTTCG
TTCGCGCTGCTCGCCATCGGCTTTCGTCTGAGCCCCGGCGCGCCGCAGCTCGGGCTACTCGCGCTCGGCATGTTCGTCGT
CGCCGGCACGTCGGGGCCCGCGGGCGCGATGGTCGCGAACCTCACGCCGCCGTCGATCCACTCGCCCGCGTTCGCGACGC
TCACGCTCGTCAACAACCTGCTCGGGCTCGCGCCCGGGCCGCTCGTCACCGGCTTCATCGCCGACCGGATCGGGCTCGTC
GGCGCGTTGCAGATCGCGCCGCTCGTCGCGCTCGCCTCGGCGTTCGCGTTCGCGGTCGGCCGCTTCCGTTACGGCGACGG
GCTGCGCCGCCTGAATCCGCTGTCGCCGTCGGCCGCCGCCGAATGA

Upstream 100 bases:

>100_bases
CGACGGCCGGCCCCCGACCCGGGCCGAGCCGAAACACGAACGGTCCCGCGCGGCGGCACGCGCGCGAGAGAACCGGCGCC
GCGAACCGGAGGAGACGATC

Downstream 100 bases:

>100_bases
ATCGCTTCAGGAGTGCTCACCGATGAATGGCCTGTCTTCCACCGTGCTGATCGTGCCGGGGCTGCGCGGCCACGTGCCGG
ATCACTGGCAGACGCTGCTC

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MHIHPADVDDGALAAPIPRPYAWTVFALAFALLLSDYMSRQVLNAVFPLLKAAWGLSDTRLGSLSGIVALMVGTLTFPLS
VLADRWGRVRSITLMAALWSVATLGCAAATSYGELLVARAFVGVGEAAYGSVGVALILGLFPPHLRSTLTGAFMAGGAFG
SVLGMALGGAVATQLGWRASFGAMACLGFALVVCFRLVVTERRIAGNGARAARSGRERAPALAHASLRTVLAELFSTVSV
VCAYVGSGLQLFIMGAVIAWMPSFLNRYYALPPDKAAAAAAGFVLLGGSGMIACGIVTDRLSRACPERKWAMAIVYCAIS
FALLAIGFRLSPGAPQLGLLALGMFVVAGTSGPAGAMVANLTPPSIHSPAFATLTLVNNLLGLAPGPLVTGFIADRIGLV
GALQIAPLVALASAFAFAVGRFRYGDGLRRLNPLSPSAAAE

Sequences:

>Translated_441_residues
MHIHPADVDDGALAAPIPRPYAWTVFALAFALLLSDYMSRQVLNAVFPLLKAAWGLSDTRLGSLSGIVALMVGTLTFPLS
VLADRWGRVRSITLMAALWSVATLGCAAATSYGELLVARAFVGVGEAAYGSVGVALILGLFPPHLRSTLTGAFMAGGAFG
SVLGMALGGAVATQLGWRASFGAMACLGFALVVCFRLVVTERRIAGNGARAARSGRERAPALAHASLRTVLAELFSTVSV
VCAYVGSGLQLFIMGAVIAWMPSFLNRYYALPPDKAAAAAAGFVLLGGSGMIACGIVTDRLSRACPERKWAMAIVYCAIS
FALLAIGFRLSPGAPQLGLLALGMFVVAGTSGPAGAMVANLTPPSIHSPAFATLTLVNNLLGLAPGPLVTGFIADRIGLV
GALQIAPLVALASAFAFAVGRFRYGDGLRRLNPLSPSAAAE
>Mature_441_residues
MHIHPADVDDGALAAPIPRPYAWTVFALAFALLLSDYMSRQVLNAVFPLLKAAWGLSDTRLGSLSGIVALMVGTLTFPLS
VLADRWGRVRSITLMAALWSVATLGCAAATSYGELLVARAFVGVGEAAYGSVGVALILGLFPPHLRSTLTGAFMAGGAFG
SVLGMALGGAVATQLGWRASFGAMACLGFALVVCFRLVVTERRIAGNGARAARSGRERAPALAHASLRTVLAELFSTVSV
VCAYVGSGLQLFIMGAVIAWMPSFLNRYYALPPDKAAAAAAGFVLLGGSGMIACGIVTDRLSRACPERKWAMAIVYCAIS
FALLAIGFRLSPGAPQLGLLALGMFVVAGTSGPAGAMVANLTPPSIHSPAFATLTLVNNLLGLAPGPLVTGFIADRIGLV
GALQIAPLVALASAFAFAVGRFRYGDGLRRLNPLSPSAAAE

Specific function: Aldohexuronate transport system [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI2367379, Length=386, Percent_Identity=25.9067357512953, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17557872, Length=425, Percent_Identity=25.1764705882353, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17539092, Length=402, Percent_Identity=25.6218905472637, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45364; Mature: 45364

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIHPADVDDGALAAPIPRPYAWTVFALAFALLLSDYMSRQVLNAVFPLLKAAWGLSDTR
CCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LGSLSGIVALMVGTLTFPLSVLADRWGRVRSITLMAALWSVATLGCAAATSYGELLVARA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVGVGEAAYGSVGVALILGLFPPHLRSTLTGAFMAGGAFGSVLGMALGGAVATQLGWRAS
HHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCH
FGAMACLGFALVVCFRLVVTERRIAGNGARAARSGRERAPALAHASLRTVLAELFSTVSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHH
VCAYVGSGLQLFIMGAVIAWMPSFLNRYYALPPDKAAAAAAGFVLLGGSGMIACGIVTDR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCEEEECCCCEEEHHHHHHH
LSRACPERKWAMAIVYCAISFALLAIGFRLSPGAPQLGLLALGMFVVAGTSGPAGAMVAN
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEC
LTPPSIHSPAFATLTLVNNLLGLAPGPLVTGFIADRIGLVGALQIAPLVALASAFAFAVG
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFRYGDGLRRLNPLSPSAAAE
HHHHCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MHIHPADVDDGALAAPIPRPYAWTVFALAFALLLSDYMSRQVLNAVFPLLKAAWGLSDTR
CCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LGSLSGIVALMVGTLTFPLSVLADRWGRVRSITLMAALWSVATLGCAAATSYGELLVARA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVGVGEAAYGSVGVALILGLFPPHLRSTLTGAFMAGGAFGSVLGMALGGAVATQLGWRAS
HHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCH
FGAMACLGFALVVCFRLVVTERRIAGNGARAARSGRERAPALAHASLRTVLAELFSTVSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHH
VCAYVGSGLQLFIMGAVIAWMPSFLNRYYALPPDKAAAAAAGFVLLGGSGMIACGIVTDR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCEEEECCCCEEEHHHHHHH
LSRACPERKWAMAIVYCAISFALLAIGFRLSPGAPQLGLLALGMFVVAGTSGPAGAMVAN
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEC
LTPPSIHSPAFATLTLVNNLLGLAPGPLVTGFIADRIGLVGALQIAPLVALASAFAFAVG
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFRYGDGLRRLNPLSPSAAAE
HHHHCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]